scholarly journals INFLUENCE OF PIK-ANTISTRESS FODDER ADDITIVE ON THE CONTENT OF MACROELEMENTS IN BLOOD AND TISSUE OF BROILER CHICKENS OF INDUSTRIAL GROWING

2021 ◽  
Vol 248 (4) ◽  
pp. 151-155
Author(s):  
A.V. Miftahutdinov ◽  
◽  
E.R. Sayfulmulukov ◽  
Keyword(s):  
Bone Tissue ◽  
Serum Calcium ◽  
Growth And Development ◽  
Broiler Chickens ◽  
Mineral Metabolism ◽  
Ash Content ◽  
Active Part ◽  
Pectoralis Minor ◽  
Calcium Magnesium ◽  
Technological Stress

Growth and development of broiler chickens with intensive fattening, especially in the finishing period, reaches a peak in intensity. Under conditions of technological stress, mineral metabolism takes an active part in the development of the adaptation syndrome. Feeding the bird with a stress protector at a dose of 1269 g / t of feed led to a statistically significant increase in the ash content of the pectoralis minor, serum calcium, magnesium in the bone tissue and a decrease in phosphorus in the pectoralis minor; at a dose of 1693 g / t of feed, it significantly increased the ash content of the skin, the content of calcium in the blood, magnesium in the bone tissue, and reduced the level of phosphorus in the femoral muscles.

Study of Calcium, Magnesium and Phosphorus Levels among Hypothyroid Patients in Trichy, Tamil Nadu

2021 ◽  
Vol 8 (30) ◽  
pp. 2797-2803
Author(s):  
Rasheed Khan M ◽  
Thivyah Prabha A.G ◽  
Siva Kumar K
Keyword(s):  
Serum Calcium ◽  
Tamil Nadu ◽  
Mineral Metabolism ◽  
Clinical Manifestations ◽  
Research Centre ◽  
Calcium Phosphorus ◽  
Calcium Magnesium ◽  
Hypothyroid Patients ◽  
Thyroid Dysfunctions

BACKGROUND Mineral metabolism is frequently disturbed in thyroid dysfunctions. Among thyroid dysfunctions, hypothyroidism is one of the most common form resulting from the deficiency of thyroid hormones. Studies done on serum calcium, phosphorus and magnesium in hypothyroid patients earlier have conflicting results. Hence the present study has been undertaken to study the levels of serum calcium, phosphorus, and magnesium among hypothyroid patients and analyse their correlation with thyroid stimulating hormone (TSH). METHODS The case control study was conducted in the Department of Biochemistry in Trichy SRM Medical College Hospital and Research Centre for a period of 6 months from 2017 January to July 2017. The study was undertaken involving 50 hypothyroid cases and 50 healthy volunteers as controls after proper ethical clearance and informed consent of all the study subjects. Serum calcium, phosphorus and magnesium were measured along with tri-iodothyronine (FT3), tetra-iodothyronine (FT4) and TSH among all study subjects. Statistical analysis of data was done using statistical package for social sciences (SPSS) software. RESULTS The mean value of serum total calcium and total magnesium was lower among hypothyroid cases and phosphorus value was increased as compared to controls. (P < 0.001) Statistically significant negative correlation was observed between serum calcium, magnesium and TSH among hypothyroid cases. Statistically significant positive correlation was observed between serum phosphorus and TSH among hypothyroid cases. CONCLUSIONS Among hypothyroid patients the values of serum calcium, magnesium and phosphorus is significantly altered. Thyroid disorders have an important role in bone and mineral metabolism. Thus, monitoring of these minerals among hypothyroid patients in regular follow up may effectively improve the clinical manifestations in them. Hence, monitoring of mineral status of the hypothyroid patients on follow-up will be of benefit to the patients. KEYWORDS Hypothyroidism, Calcium, Phosphorus, Magnesium, Minerals

scholarly journals Deoxynivalenol in the Diet Impairs Bone Mineralization in Broiler Chickens

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 352 ◽  
Author(s):  
Marsel Keçi ◽  
Annegret Lucke ◽  
Peter Paulsen ◽  
Qendrim Zebeli ◽  
Josef Böhm ◽  
...  
Keyword(s):  
Serum Calcium ◽  
Broiler Chickens ◽  
Dry Matter ◽  
Clinical Biochemistry ◽  
Bone Mineralization ◽  
Fusarium Species ◽  
Ash Content ◽  
Gut Barrier Function ◽  
Calcium And Phosphorus ◽  
Phosphorus Intake

Deoxynivalenol (DON) is one of the most abundant and important trichothecene mycotoxins produced by Fusarium species. In chickens, DON intake causes feed refusal, impairs performance, gut barrier function, and immunity, and raises oxidative stress. To determine the effect of DON on bone mineralization and serum calcium and phosphorus, 80 newly-hatched chickens were fed 4 diets with 0, 2.5, 5, and 10 mg DON/kg feed in this pilot study. In week 5, chickens were euthanized, femur and tibiotarsus bones were separated from the meat, and after incineration ash composition, as well as serum calcium and phosphorus, were determined using clinical biochemistry. Dietary DON reduced chicken dry matter, calcium, and phosphorus intake, and subsequently body and leg weight. DON affected bone density and composition of the tibiotarsus more drastically than of the femur. However, lower mineral intake did not solely explain our observations of the quadratically lower tibiotarsus density and ash content, as well as linearly decreased Ca content in the femur and tibiotarsus with increasing DON levels. Linearly decreasing serum phosphorus concentrations with increasing DON levels further supported impaired mineral homeostasis due to DON. In conclusion, already low dietary DON contamination of 2.5 mg/kg feed can compromise bone mineralization in chickens.

The influence of nutrition and seasonal conditions on mineral status in the reindeer

1977 ◽  
Vol 55 (4) ◽  
pp. 648-655 ◽  
Author(s):  
H. Hyvärinen ◽  
T. Helle ◽  
M. Nieminen ◽  
P. Väyrynen ◽  
Raija Väyrynen
Keyword(s):  
Serum Calcium ◽  
Mineral Metabolism ◽  
Late Pregnancy ◽  
Serum Copper ◽  
Late Winter ◽  
Winter Food ◽  
Different Seasons ◽  
Zinc Concentrations ◽  
Calcium Magnesium ◽  
Food Conditions

Body weight, serum sodium, potassium, calcium, magnesium, copper, and zinc concentrations, and alkaline phosphatase (EC 3.1.3.1) activity were measured in freely grazing reindeer in Kuusamo, Finland (66°30′N), at four different seasons in the year. The same parameters were also measured in late winter in a group of artificially fed reindeer in Kuusamo and a group in Enontekiö, Finland (68°30′N), which were grazing freely in very poor conditions. Some weeks after sampling about 40% of the reindeer in this latter area died of malnutrition. Bone densities were measured in some of these animals.The reindeer in Enontekiö had suffered from severe mineral deficiency. Serum calcium, magnesium, and copper concentrations were very low. It is assumed that the final death of the animals may have been caused by a disturbance in mineral metabolism. Serum calcium concentration was also low in the freely grazing group with near normal winter food conditions in Kuusamo. It is suggested that the reindeer compensate for the poor mineral content of the winter food by using the skeleton as a mineral bank even in normal winter. A seasonal cycle was found in serum copper concentration in the hinds, values being high in late pregnancy and after parturition. Serum potassium and zinc concentrations were lowest in autumn and winter.

SERUM BIOCHEMICAL CHANGES IN KETOTIC BUFFALOES ( BUBALUS BUBALIS)

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
Usha Choudhary ◽  
Meenaxi Sareen ◽  
Anil Moolchandani
Keyword(s):  
Serum Calcium ◽  
Bubalus Bubalis ◽  
Biochemical Changes ◽  
Blood Analysis ◽  
Serum Phosphorus ◽  
Serum Minerals ◽  
Calcium Magnesium ◽  
Serum Biochemical ◽  
Calcium And Magnesium

The present study was carried out to evaluate the variations in serum minerals ( viz. calcium, magnesium and phosphorus) and transaminases in ketotic buffaloes. Results of blood analysis revealed a significant (P<0.05) reduction in serum phosphorus in ketotic buffaloes whereas nonsignificant (P>0.05) difference occur in serum calcium and magnesium in ketotic buffaloes as compared to control. At the same time significant increase in transaminases GPT, GOT and GGT have been observed .

scholarly journals INFECTIOUS STUNTING SYNDROME ASSOCIATED WITH DISTURBANCES OF MINERAL METABOLISM AND BONE DEVELOPMENT IN BROILER CHICKENS

1999 ◽  
Vol 47 (3) ◽  
pp. 361-378 ◽  
Author(s):  
Glávits ◽  
G. Sályi ◽  
R. Glávits
Keyword(s):  
Growth Retardation ◽  
Broiler Chickens ◽  
Neuronal Degeneration ◽  
Bone Development ◽  
Mineral Metabolism ◽  
Digestive Enzyme ◽  
Small Intestinal Mucosa ◽  
Vacuolar Degeneration ◽  
Leg Weakness ◽  
Small Intestinal

On a broiler farm with a rearing capacity of about 200,000 chickens, a disease characterised by growth retardation, variability in chick size, 'leg weakness', diarrhoea and increased mortality at 3 weeks of age occurred repeatedly, in several successive broiler flocks. Gross and histopathological findings were dominated by widening of the hypertrophic and ossification layers of the physes of long bones as well as by thickening, unevenness and defective calcification of the cartilage trabeculae. In the parathyroid gland, vacuolar degeneration of the cytoplasm of glandular epithelial cells, connective tissue proliferation and, here and there, cyst formation were seen. Additional findings included severe cerebellar oedema and neuronal degeneration. The pancreatic, myocardial and intestinal changes typical of infectious stunting syndrome (ISS) occurred only in a mild form. Four-week-old chickens exhibiting 'leg weakness' had significantly lower blood inorganic phosphate concentration and tibial ash content as compared to healthy chickens. The disease was successfully transmitted by oral administration of small intestinal homogenate from affected chickens. In a second experiment, however, the disease could not be transmitted with intestinal homogenate sterilized by irradiation. Large doses of vitamin D3reduced the rate of growth retardation and defective calcification of bones. The digestive enzyme activities of the pancreas and small intestinal mucosa of 'infected' chickens were decreased as is typical of ISS.

scholarly journals Normocalcemic primary hyperparathyroidism

2010 ◽  
Vol 54 (2) ◽  
pp. 106-109 ◽  
Author(s):  
John P. Bilezikian ◽  
Shonni J. Silverberg
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Serum Calcium ◽  
Kidney Stones ◽  
Bone Disease ◽  
Clinical Phenotype ◽  
Mineral Metabolism ◽  
Historical View ◽  
History Of ◽  
Excessive Secretion

Primary hyperparathyroidism is a common disorder of mineral metabolism characterized by incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands. The historical view of this disease describes two distinct entities marked by two eras. When primary hyperparathyroidism was first discovered about 80 years ago, it was always symptomatic with kidney stones, bone disease and marked hypercalcemia. With the advent of the multichannel autoanalyzer about 40 years ago, the clinical phenotype changed to a disorder characterized by mild hypercalcemia and the absence of classical other features of the disease. We may now be entering a 3rd era in the history of this disease in which patients are being discovered with normal total and ionized serum calcium concentrations but with parathyroid hormone levels that are consistently elevated. In this article, we describe this new entity, normocalcemic primary hyperparathyroidism, a forme fruste of the disease.

scholarly journals Role of reduced thyroid hormone status on bone mineral metabolism

2021 ◽  
Vol 19 (2) ◽  
pp. 26-29
Author(s):  
X Lourdes Sandy ◽  
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Hormones ◽  
Bone Mineral ◽  
Serum Calcium ◽  
Mineral Metabolism ◽  
Bone Mineral Metabolism ◽  
Hormone Status ◽  
Calcium And Phosphorus ◽  
Hypothyroid Patients

Background: The most common endocrine disorder is hypothyroidism which accounts to 11%. Thyroid hormones have a wide array of functions such as physiological growth and development of skeletal system, maintenance of basal metabolic rate and regulation of various metabolisms, including mineral metabolism. Nowadays due to its direct action on bone turn over, thyroid hormones are considered to have an important role on bone mineral metabolism. Thyroid disorders are important cause for secondary osteoporosis. So the present study was done to know the levels of bone minerals, calcium and phosphorus in hypothyroidism and its relation with thyroid hormone levels. Methods: A case-control study was conducted on 30 hypothyroid patients and 30 euthyroid healthy controls in the age group of 20-60 years. Blood samples were collected from all the study population. Serum total triiodothyronine, total thyroxine and TSH by Enzyme-Linked Immunosorbent Assay, Serum calcium by Arsenazo III method, phosphorous by ammonium molybdate method were estimated. Results: Serum calcium levels in cases was found to significantly reduced when compared to controls (p<0.001). Serum phosphorous levels also showed considerable elevation in cases when compared to controls (p<0.001). There was a significant negative correlation between TSH and serum calcium in cases. Conclusion: The present study indicated the important role of reduced thyroid hormone status on bone mineral metabolism. This study concludes that serum calcium was significantly reduced and phosphorus levels were significantly increased in hypothyroid patients when compared to euthyroid control subjects. So frequent monitoring of serum calcium and phosphorus in hypothyroid patients would reduce the burden of bone pathologies.

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