System of antioxidant protection of the body of piglets under the action of feed additive “Sylimevit”

One of the conditions for obtaining high-quality pig products is the use of feed additives, which contain all the necessary biologically active substances, eliminating their deficiency in feed and acting as catalysts for metabolic processes in pigs. That is why the aim of the study was to study the effect of feed additive “Sylimevit” on the enzymatic and non-enzymatic parts of the antioxidant system of piglets after weaning. Two groups of piglets were formed – control and experimental, in the amount of 10 individuals in each group, selected on the principle of analogues – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. Feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. Feeding piglets Silimevit feed enhances their antioxidant status. The use of this feed additive in piglets contributed to the activation of both enzymatic and non-enzymatic parts of the antioxidant defense system of piglets after weaning, as indicated by an increase in blood 35-day-old piglets superoxide dismutase activity by 26.9 % (P < 0.001), catalase – 41.1 % (P < 0.001), glutathione peroxidase – by 52.7 % (P < 0.05), glutathione reductase – by 53.5 % (P < 0.05), the content of reduced glutathione – by 75 % (P < 0.001). This is due to the fact that silimevit contains active substances such as milk thistle and vitamins, which are strong direct-acting antioxidants and directly interact with free radicals and reactive oxygen species.

The level of products of lipid peroxidation in the blood of piglets at the action feed additive “Sylimevit”

Intensive pig breeding has been reported in the literature to suggest that early weaning of piglets from sows is an extreme stimulus that reduces the protective and adaptive responses of piglets. That is why the aim of the study was to study the effect of the feed additive “Sylimevit” on the level of lipid peroxidation products of piglets after weaning. Two groups of piglets were formed – control and experimental in the amount of 10 individuals in each group, selected on the principle of analogs – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. While feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. The technological stress of weaning piglets from sows is accompanied by a gradual probable intensification of lipid peroxidation processes. Feeding Sylimevit feed to piglets after weaning helped to reduce the content of intermediate and final products of lipid peroxidation: lipid hydroperoxides – by 52 % (P < 0.001) and TBA-active products – by 22.5 % (P < 0.01). Thus, feeding the piglets of the experimental group of the feed additive “Sylimevit” helped to suppress the processes of lipid peroxidation in animals. Thus, the results of the use of feed additive “Sylimevit” in weaned piglets showed a pronounced antioxidant effect. The components of the feed additive directly interacted with reactive oxygen species and free radicals, preventing the development of oxidative stress.

Influence of the heat transfer coefficient on the level of residual stress after heat treatment of the VVER-1000 reactor baffle

Background. Improvement of the methodology for the computational analysis of residual stresses in the structural elements of the reactor is an integral part of the work when extending the service life of NPP power units. Objective. Determine the value of residual technological stress arising in the baffle of a VVER-1000 reactor during welding and postweld heat treatment according to the austenitizing mode. To evaluate the effect of considering the dependence of the heat transfer coefficient on the temperature of the baffle surface at cooling in air during heat treatment. Methods. Numerical modeling of the stress-strain state of the baffle during welding and postweld heat treatment was carried out using the finite element method. Results. It was determined that in the process of heat treatment according to the austenitizing mode, the residual welding stress in the baffle are almost completely relaxed. Due to the high temperature gradient during rapid cooling in air after heating in the process of austenitization, new rather high residual stresses are formed in the zones of the baffle with the greatest metal thickness. Conclusions. Based on the results of the investigation, a high level of residual technological stress was determined, which should be considered when calculating the justification for extending the service life of the VVER-1000 reactor baffle.

INFLUENCE OF PIK-ANTISTRESS FODDER ADDITIVE ON THE CONTENT OF MACROELEMENTS IN BLOOD AND TISSUE OF BROILER CHICKENS OF INDUSTRIAL GROWING

Growth and development of broiler chickens with intensive fattening, especially in the finishing period, reaches a peak in intensity. Under conditions of technological stress, mineral metabolism takes an active part in the development of the adaptation syndrome. Feeding the bird with a stress protector at a dose of 1269 g / t of feed led to a statistically significant increase in the ash content of the pectoralis minor, serum calcium, magnesium in the bone tissue and a decrease in phosphorus in the pectoralis minor; at a dose of 1693 g / t of feed, it significantly increased the ash content of the skin, the content of calcium in the blood, magnesium in the bone tissue, and reduced the level of phosphorus in the femoral muscles.

The Influence of Technological Stress on the Protective Properties of Pig Skin Depending on Age

The skin performs the most important physiological functions of the body. The protective function is the main among them. This article presents the results of studies of how the technological stress affects the protective properties of pig skin depending on the animals’ age. The parameters of the skin, characterizing the epidermis, the main protective skin barrier, were studied in domestic Poltava Meat Breed pigs of different ages. The skin epidermis in animals of all studied age groups is actively involved in the performance of protective functions. Upon reaching the live weight of 100 kg, the young boars of the breed experience a great technological load, which causes tension in the skin protective systems and, thus, activation of these systems. This results in greater values of the epidermis thickness comparing to adult boars (by 17.22% (p⩽0.05)) due to an increase in its inner (underlying) layers (by 33.05% (p⩽0.001)). The stratum corneum of the young boars’ epidermis is thinner but more dense, with pronounced sudanophilia. With pigs reaching their adulthood, the tension in their protective factors decreases and stabilizes. In adult boars, the stratum corneum is thicker (a significant difference is 6.82 μm or 28.14%), but it is more susceptible to keratinization, is looser and has pronounced fibrillation. These changes probably mark the already developed adaptation to the existing natural and technological conditions.

INTEGRAL HEMATOLOGICAL INDICES OF NON-SPECIFIC RESISTANCE OF PIGS AS A CRITERION OF THEIR PRODUCTIVE QUALITIES UNDER THE INFLUENCE OF TECHNOLOGICAL STRESS FACTORS

The research was carried out on a purebred livestock of the main sows of the Poltava meat breed. In the blood, the amount of leukocyte formula was determined and, on the basis of the primary data, integral leukocyte indices were calculated, characterizing the nonspecific resistance of the organism. Approximate reference values of blood indices were established in the population of healthy sows of the Poltava meat breed, in which technological stress led to the development of the stage of resistance. The main load under the action of technological stress in pigs is experienced by the agranulocytic link in the blood, especially monocytes. No reliable interrelationships between blood indices and productivity indicators were established, however, a direct dependence of some indices on other links of the body's resistance was revealed.

System of antioxidant protection of the body of piglets under the action of feed additive “Butaselmevit-plus”

The aim of the study was to investigate the effect of the feed additive “Butaselmevit-plus” on the state of the antioxidant defense system of piglets during weaning. The experiments were conducted on the basis of the LTD “KOSHET” Mukachevo district of Zakarpattia region. Two groups of piglets were formed – control and experimental, in the amount of 10 individuals in each group, selected on the principle of analogs – age, breed and body weight. Animals were fed according to the norms for this age of pigs. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests for further maintenance during fattening and rearing with a change in the structure of the diet, which served as technological stress for the animal's body. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed additive “Butaselmevit-plus” at a dose of 100 mg/kg body weight per day. The material for the study was blood, which was taken in the morning before feeding the animals by puncture of the cranial vena cava for 20 days of life (the period before weaning), for 25 days of life (the period before weaning), for 30 days of life (2 days after weaning), for 35 days of life (7 days after weaning), 40 days of life (12 days after weaning). It is proved that feeding piglets feed additive “Butaselmevit-plus” enhanced the antioxidant status of piglets after weaning. It was found that under conditions of technological stress, the use of feed additive “Butaselmevit-plus” in the amount of 100 mg/kg body weight per day improves the antioxidant defense of the body, as evidenced by an increase in blood 35-day-old piglets superoxide dismutase activity by 26.7 % (P < 0.001), catalase – by 39.5 % (P < 0.001), glutathione peroxidase – by 51.7 % (P < 0.05), glutathione reductase – by 52.9 % (P < 0.05), the content of reduced glutathione – at 58.3 % (P < 0.001). These results confirm the effectiveness of the use of milk thistle, methionine, selenium, and vitamins A, E, and D3 in the feed additive “Butaselmevit-plus” to piglets in the period before and after weaning to activate the protective systems of their body.

Fear, Stress, Resilience and Coping Strategies during COVID-19 in Spanish University Students

COVID-19 (2019 coronavirus pandemic) and the resulting confinement has had an impact on mental health and the educational environment, affecting the stress, concerns, fear, and life quality of the university population. This study aimed to examine the correlation between fear of COVID-19, stress with COVID-19, and technological stress in university students, and their resilience, self-esteem, and coping strategies. The final sample comprised 180 Spanish university students, with an average age of 20.76 years (SD = 4.59). The above-mentioned effects were administered a series of self-report scales. We found statistically significant associations between fear of COVID-19 and stress with COVID-19, technological stress (total score), overload, and complexity (subdimensions of technological stress). Likewise, we found inverse relationships between the students’ fear of COVID-19 and the use of the coping strategy, cognitive restructuring. Ascertaining the factors that influence the coping strategies of undergraduate university students and their fears, psychological stress, and resilience provides valuable information for the development of educational interventions. This research has relevant implications for the diagnosis, orientation, and design of psycho-educational and clinical interventions that can improve students’ well-being and training for effective coping strategies for daily stress and this pandemic situation.

CORRECTION OF TECHNOLOGICAL STRESS BY LOW-INTENSITY LASER RADIATION

Intensive industrial technologies in animal husbandry lead to an increase in cases of stress and metabolic disorders, which affects the quality of dairy and meat products. It is important to increase the resistance of animals to environmental factors by non-drug methods. The aim of the work is to study the effect of technological stress and low-intensity laser radiation at the cell level.