scholarly journals Colonic Transit Time Evaluation in Patients with Functional Constipation

2013 ◽  
Vol 1 (2) ◽  
pp. 48-52
Author(s):  
Masoud Taheri ◽  
Rahmatollah Rafiei ◽  
Zahra Torabi ◽  
Ali Toghiani ◽  
Sina Taherzadeh
Keyword(s):  
Transit Time ◽  
Gastrointestinal Symptoms ◽  
Functional Constipation ◽  
Colonic Transit ◽  
Colonic Transit Time ◽  
P Value ◽  
Cross Sectional ◽  
Colon Transit Time ◽  
Significant Difference ◽  
Colon Transit

Introduction: Functional constipation is one of the most common gastrointestinal symptoms which could affect patients’ quality of life. The colonic transit time test could be used for determining functional constipation subtypes. The aim of our study was to determine the abnormalities of the subtypes of functional constipation using CTT. Methods and Materials: This cross-sectional study was performed on 85 patients in 2011 in Shariaaty Hospital, Isfahan. All the patients received 60 radio-opaque markers, and they underwent radiological evaluation 5 days afterwards. Functional constipation was determined according to the distribution of the markers in the colon. Result: The samples consisted of 24 males and 61 females at a mean age of 42.7 ± 16.28 years. The colonic transit time results showed that 71 patients had normal transit time, 6 had a composite type, 5 had slow transit, and 3 had pelvic delay. There was no significant difference between sex and colon transit time types (P value =0.32). The mean colon transit time in our study was 51.8 ± 16.3 hours. Conclusion: Functional constipation patients should undergo CTT, especially those who use maneuvers for defecation and those who need more time for defecation.[GMJ. 2012;1(2):48-52]

scholarly journals Prediction of Inadequate Bowel Preparation Using Total and Segmental Colon Transit Time in Patients with Chronic Constipation: Some Different Outcomes

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Chunying Zhai ◽  
Qiyang Huang ◽  
Ningli Chai ◽  
Wengang Zhang ◽  
Enqiang Linghu
Keyword(s):  
Transit Time ◽  
Bowel Preparation ◽  
Multivariate Logistic Regression Analysis ◽  
Functional Constipation ◽  
Colonic Transit ◽  
Slow Transit Constipation ◽  
Roc Curve Analysis ◽  
Colon Transit Time ◽  
Inadequate Bowel Preparation ◽  
Colon Transit

Aims. Radio-opaque markers have been widely used in the study of colon motility in patients with chronic functional constipation (FC). Here, we evaluate the relationship between the colon transit time (CTT) and the Boston Bowel Preparation Scale (BBPS) to determine whether CTT is a sufficient predictor of bowel preparation in patients with chronic functional constipation. Methods. A total of fifty-six patients with constipation and fifty-two healthy controls (HC) were enrolled in this study. All subjects underwent the colonic transit study using radio-opaque markers and were given a follow-up colonoscopy examination on day 3 to 7 to determine BBPS. The correlation between total and segmental CTT and BBPS was evaluated, and risk factors for predicting inadequate bowel preparation were determined. Results. In our study, we found some distinct outcomes compared with previous studies. The mean total CTT (TCTT) was determined to be 43.37±18.82 h in the FC group and 23.08±10.18 h in the HC group. This difference was found to be significant for both the total and segmental CTTs between the two groups (P<0.05). Further, TCTT was negatively correlated with BBPS both in the FC (r=−0.899, 95% CI -0.748 to -0.925, P<0.001) and the HC (r=−0.978, 95% CI -0.854 to -1.003, P=0.004) groups, as was segmental CTTs and segmental BBPS (P<0.05). In the case of patients with slow transit constipation, multivariate logistic regression analysis indicated that prolonged TCTT (OR 0.722, 95% CI 0.589-0.885, P=0.002) was independently associated with poor bowel preparation. The total and right to left CTTs were found to predict inadequate bowel preparation and exhibited the best sensitivity and specificity at 48.0 h, 15.5 h, 17.5 h, and 19.0 h, based on ROC curve analysis. Conclusions. The CTT test represents a valuable method for predicting the level of bowel preparation prior to a colonoscopy examination. That is, both total and segmental CTTs can be considered an objective predictor of bowel preparation prior to colonoscopy. The present study demonstrates some distinct results relative to previous studies, including STC subtype proportion in FC, the proportion of inadequate bowel preparation in the STC subtype, and the cut-off value of TCTT for predicting inadequate bowel preparation.

scholarly journals Longer colonic transit time is associated with laxative and drug use, lifestyle factors, and symptoms of constipation

2018 ◽  
Vol 7 (10) ◽  
pp. 205846011880723 ◽  
Author(s):  
Johan Bohlin ◽  
Erik Dahlin ◽  
Julia Dreja ◽  
Bodil Roth ◽  
Olle Ekberg ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Drug Use ◽  
Transit Time ◽  
Gastrointestinal Symptoms ◽  
Coffee Consumption ◽  
Lifestyle Factors ◽  
Colonic Transit ◽  
Stool Frequency ◽  
Colonic Transit Time ◽  
Female Sex

Background Gastrointestinal symptoms and changes in colonic transit time (CTT) are common in the population. Purpose To evaluate consecutive patients who had been examined for CTT, along with completion of a diary about laxative and drug use, lifestyle factors, and gastrointestinal symptoms, to identify possible associations with longer or prolonged CTT. Material and Methods A total of 610 consecutive patients had undergone the radiopaque marker method with an abdominal X-ray for clinical purposes. The patients had completed a diary regarding medical treatment, lifestyle factors, stool habits, and their perceived constipation and abdominal pain during the examination period. The associations between CTT and laxative use, lifestyle factors, stool habits, and symptoms were calculated by logistic regression. Results Women had longer CTT (2.5 [1.6–3.9] vs. 1.7 [1.1–3.0] days, P < 0.001), lower weekly stool frequency (6 [3–10] vs. 8 [5–12], P = 0.001), and perceived more constipation ( P = 0.025) and abdominal pain ( P = 0.001) than men. High coffee consumption ( P = 0.045), bulk-forming ( P = 0.007) and osmotic ( P = 0.001) laxatives, and lower stool frequency, shaped stool, and perceived constipation ( P for trend < 0.001) were associated with longer CTT. In total, 382 patients (63%) were treated with drugs affecting motility. In the 228 patients without drug treatment, longer CTT was associated with female sex and smoking, and lower frequency of symptoms and prolonged CTT were observed compared to patients using drugs. Tea, alcohol, and abdominal pain did not associate with CTT. Conclusions Female sex, coffee, smoking, drug use, infrequent stools, shaped stool, and perception of constipation are associated with longer or prolonged CTT.

Assessment of stool frequency and colonic transit time in Indian children with functional constipation and healthy controls

2018 ◽  
Vol 37 (5) ◽  
pp. 410-415 ◽  
Author(s):  
Upender Shava ◽  
Surender Kumar Yachha ◽  
Anshu Srivastava ◽  
Ujjal Poddar ◽  
Moinak Sen Sarma
Keyword(s):  
Transit Time ◽  
Functional Constipation ◽  
Colonic Transit ◽  
Stool Frequency ◽  
Colonic Transit Time ◽  
Healthy Controls ◽  
Indian Children

scholarly journals Rectal Hyposensitivity Is Associated With a Defecatory Disorder But Not Delayed Colon Transit Time in a Functional Constipation Population

Medicine ◽  
2016 ◽  
Vol 95 (19) ◽  
pp. e3667 ◽  
Author(s):  
Ting Yu ◽  
Dong Qian ◽  
Yongping Zheng ◽  
Ya Jiang ◽  
Ping Wu ◽  
...  
Keyword(s):  
Transit Time ◽  
Functional Constipation ◽  
Colon Transit Time ◽  
Rectal Hyposensitivity ◽  
Colon Transit

DA-9701 improves colonic transit time and symptoms in patients with functional constipation: A prospective study

2017 ◽  
Vol 32 (12) ◽  
pp. 1943-1948 ◽  
Author(s):  
Su Young Kim ◽  
Hyun Sun Woo ◽  
Kyoung Oh Kim ◽  
Sung Han Choi ◽  
Kwang An Kwon ◽  
...  
Keyword(s):  
Prospective Study ◽  
Transit Time ◽  
Functional Constipation ◽  
Colonic Transit ◽  
Colonic Transit Time ◽  
A Prospective Study

scholarly journals Effects of rice-based and wheat-based diets on bowel movements in young Korean women with functional constipation

2020 ◽  
Vol 74 (11) ◽  
pp. 1565-1575
Author(s):  
Su-Jin Jung ◽  
Mi-Ra Oh ◽  
Soo-Hyun Park ◽  
Soo-Wan Chae
Keyword(s):  
Fatty Acid Content ◽  
Brown Rice ◽  
Functional Constipation ◽  
Bowel Function ◽  
Colon Transit Time ◽  
Dietary Fiber Intake ◽  
Significant Difference ◽  
Before And After ◽  
Bowel Movements ◽  
Colon Transit

Abstract Background Although several studies have reported the effects that dietary fiber intake from different types of grains and fiber components have on bowel movements, insufficient attention has been paid to comparing and evaluating the effects of rice-based and wheat-based diets. This study compared and evaluated the effects of ingesting rice-based (brown rice-based diet: BRD; white rice-based diet: WRD) and wheat-based diet (WD) on the bowel movements of young women with functional constipation. Method Based on an open, randomized, controlled, and parallel design, 39 subjects were assigned to BRD, WRD, and WD groups (13 in each group). Each participant had received three types of experimental diets over the course of 4 weeks and we recommended that the subjects eat only the test diet provided during the study. Primary outcomes (total colon transit time TCTT) and secondary outcomes (bowel movements, short-chain fatty acid content, and fecal enzyme activity) were compared before and after the 4-week intervention period. Results After the 4-week study, the rice-based diet (BRD and WRD) groups and the WD group had a statistically significant difference in TCTT (p = 0.028). The TCTT of the BRD group was significantly reduced (p = 0.028) compared with the WRD group (−16.5 ± 8.1 vs +6.8 ± 2.1), and the TCTT of the WD group was also significantly reduced (p = 0.022) compared with that of the WRD group (−17.1 ± 11.9 vs +6.8 ± 2.1). Conclusion Among women with functional constipation, the BRD and WD both improved bowel function by reducing TCTT and increasing the number of bowel movements compared with the WRD group.

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