Brain CT Scan in Stroke

In patients came with suspicious cerebrovascular accidents, CT scan can play a major roll for diagnosis and treatment planning. In these patients we can do non contrast enhanced CT scan followed by perfusion CT scan and CT angiography. This three step CT scanning can be called multimodal CT. This strategy can help us to roll out hemorrhage and other differential diagnosis, it is useful to detect the site of vascular occlusion, the infarcted zone and the at risk salvageable tissue, also we can assess collateral circulation. This multimodal CT scan take about 10 to 15minuts.

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A novel nonsense mutation in ARMC5 causes primary bilateral macronodular adrenocortical hyperplasia

BMC Medical Genomics ◽

10.1186/s12920-021-00896-0 ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Wen-Tao He ◽

Xiong Wang ◽

Wen Song ◽

Xiao-Dong Song ◽

Yan-Jun Lu ◽

...

Keyword(s):

Genetic Testing ◽

Nonsense Mutation ◽

Hormone Replacement ◽

Ct Scanning ◽

Related Family ◽

Contrast Enhanced Ct ◽

Severe Diabetes ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Adrenocortical Hyperplasia

Abstract Background Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) is a rare form of adrenal Cushing’s syndrome. The slowly progressing expansion of bilateral adrenal tissues usually persists for dozens of years, leading to delayed onset with severe conditions due to chronic mild hypercortisolism. About 20–50% cases were found to be caused by inactivating mutation of armadillo repeat-containing protein 5 (ARMC5) gene. Case presentation A 51-year-old man was admitted for severe diabetes mellitus, resistant hypertension, centripedal obesity and edema. PBMAH was diagnosed after determination of adrenocorticotropic hormone and cortisol levels, dexamethasone suppression tests and abdominal contrast-enhanced CT scanning. The metabolic disorders of the patient remarkably improved after sequentially bilateral laparoscopic adrenalectomy combined with hormone replacement. Sanger sequencing showed germline nonsense mutation of ARMC5 c.967C>T (p.Gln323Ter). The second somatic missense mutation of ARMC5 was detected in one out of two resected nodules, reflecting the second-hit model of tumorigenesis. Routine genetic testing in his apparently healthy offspring showed one of two daughters and one son harbored the germline mutation. Conclusions In conclusion, our case report highlight the importance of genetic testing in the molecular diagnosis of PBMAH. Genetic screening in related family members will find out asymptomatic variant carriers to guide life-long follow-up.

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The contrast-enhanced CT scan in the diagnosis of isodense subdural hematoma

Journal of Neurosurgery ◽

10.3171/jns.1979.50.1.0064 ◽

1979 ◽

Vol 50 (1) ◽

pp. 64-69 ◽

Cited By ~ 22

Author(s):

Fong Y. Tsai ◽

James E. Huprich ◽

Hervey D. Segall ◽

James S. Teal

Keyword(s):

Cerebral Cortex ◽

Ct Scan ◽

Subdural Hematoma ◽

Correct Diagnosis ◽

Content Type ◽

Subdural Hematomas ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Fine Print

✓ The authors review 29 cases of surgically-proven isodense subdural hematomas examined by non-contrast and contrast-enhanced computerized tomography scans. Three types of isodense collections were noted: homogeneous isodense collections, mixed-density collections, and gravitational layering within subdural collections. Contrast enhancement within the cerebral cortex, cortical vessels, and subdural membranes led to the correct diagnosis in each case. Contrast-enhanced scans are essential for the evaluation of isodense subdural hematomas.

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Abdominal case of the day. Focal liver enhancement on contrast-enhanced CT scan caused by obstruction of the superior vena cava (SVC).

American Journal of Roentgenology ◽

10.2214/ajr.169.1.9207535 ◽

1997 ◽

Vol 169 (1) ◽

pp. 250-250 ◽

Cited By ~ 2

Author(s):

T E Herbener ◽

V Basile ◽

D Nakamoto ◽

H E Butler ◽

S P Pickering

Keyword(s):

Ct Scan ◽

Superior Vena Cava ◽

Superior Vena ◽

Vena Cava ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct

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Is CT Angiogram of the Abdominal Vessels Needed following the Diagnosis of Ischemic Colitis? A Multicenter Community Study

ISRN Gastroenterology ◽

10.1155/2014/756926 ◽

2014 ◽

Vol 2014 ◽

pp. 1-8 ◽

Cited By ~ 4

Author(s):

Muhammed Sherid ◽

Salih Samo ◽

Samian Sulaiman ◽

Husein Husein ◽

Sankara N. Sethuraman ◽

...

Keyword(s):

Ct Scan ◽

Ischemic Colitis ◽

Celiac Trunk ◽

Ct Angiogram ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Group 3 ◽

Group 5 ◽

Atherosclerotic Changes

Background. CT angiogram is frequently obtained after diagnosis of ischemic colitis (IC). Aims. To investigate the vascular findings of CT angiogram as compared to contrast-enhanced CT scan and whether this modality changes the management or prognosis of IC. Methods. We conducted a retrospective analysis of patients with IC from 2007 to 2013. Results. CT angiogram was performed in 34 patients (28.81%), whereas contrast-enhanced CT scan was performed in 54 patients (45.76%). In CT angiogram group, 8 patients (23.5%) had atherosclerotic changes. Stenosis was found in 12 patients (35.3%) (9: celiac trunk, 3: SMA). Among this group, one patient underwent colectomy and another underwent angioplasty of the celiac trunk who died within 30 days. Among contrast-enhanced CT scan group, 5 patients (9.3%) had atherosclerotic changes. Stenosis was found in 5 patients (9.3%) (3: celiac trunk, 1: SMA, and 1: IMA). Among this group, 3 patients had colectomy and one died within 30 days. There was no statistical difference between both groups in all vascular findings except the stenosis which was higher in CT angiogram group (P=0.0025). Neither the need for surgery nor all-cause mortality was different between both groups. Conclusion. CT angiogram did not provide any useful findings that altered the management or the prognosis of IC.

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A Comparison of Cobalt (57Co) Bleomycin Scanning and Contrast-Enhanced CT Scanning for Assessment of the Mediastinum in Lung Cancer

CHEST Journal ◽

10.1378/chest.97.5.1148 ◽

1990 ◽

Vol 97 (5) ◽

pp. 1148-1151 ◽

Cited By ~ 1

Author(s):

Christopher G. Wathen ◽

Keith M. Kerr ◽

William Reid ◽

Arthur J.A. Wightman ◽

Jonathan J.K. Best ◽

...

Keyword(s):

Lung Cancer ◽

Ct Scanning ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct

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Contrast enhanced CT scan 1-year after admission. The bifurcated surgical graft of the abdominal aorta with visceral sidegrafts is seen

ASVIDE ◽

10.21037/asvide.2018.292 ◽

2018 ◽

Vol 5 ◽

pp. 292-292

Author(s):

Paul Schoenhagen

Keyword(s):

Ct Scan ◽

Abdominal Aorta ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct

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Delayed response to proton beam treatment of hepatocellular carcinoma

BJR|case reports ◽

10.1259/bjrcr.20180125 ◽

2020 ◽

Vol 6 (1) ◽

pp. 20180125

Author(s):

Chee-Wai Cheng ◽

Mitchell Machtay ◽

Jennifer Dorth ◽

Olga Sergeeva ◽

Hangsheng Xia ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Ct Scan ◽

Proton Beam ◽

Arterial Phase ◽

Delayed Response ◽

Data Set ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Imaging Response

Hepatocellular carcinoma (HCC) has become one of the leading causes of cancer death worldwide. There has been anecdotal report regarding the effectiveness of proton beam treatment for HCC. In this pre-clinical investigation, the woodchuck model of viral hepatitis infection-induced HCC was used for proton beam treatment experiment. The radiopaque fiducial markers that are biodegradable were injected around the tumor under ultrasound guidance to facilitate positioning in sequential treatments. An α cradle mode was used to ensure reproducibility of animal positioning on the treatment couch. A CT scan was performed first for contouring by a radiation oncologist. The CT data set with contours was then exported for dose planning. Three fractionations, each 750 CcGyE, were applied every other day with a Mevion S250 passive scattering proton therapy system. Multiphase contrast-enhanced CT scans were performed after the treatment and at later times for follow-ups. 3 weeks post-treatment, shrinking of the HCC nodule was detected and constituted to a partial response (30% reduction along the long axis). By week nine after treatment, the nodule disappeared during the arterial phase of multiphase contrast-enhanced CT scan. Pathological evaluation corroborated with this imaging response. A delayed, but complete imaging response to proton beam treatment applied to HCC was achieved with this unique and clinically relevant animal model of HCC.

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Ruptured aneurysm of the hepatic artery: a mismatching diagnosis

Italian Journal of Medicine ◽

10.4081/itjm.2009.175 ◽

2013 ◽

pp. 175-178

Author(s):

Vincenzo Bua ◽

Lorenzo Marsigli ◽

Roberto Nardi ◽

Anna Maria Trivella ◽

Salvatore Isceri ◽

...

Keyword(s):

Hepatic Artery ◽

Ct Scanning ◽

Gelatin Sponge ◽

Contrast Enhanced Ct ◽

Life Saving ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Threatening Condition ◽

Life Threatening ◽

Intraabdominal Hemorrhage

Background: Hepatic aneurysms are extremely rare with very few cases reported, and most have been source of misdiagnosis and clinical pitfalls in emergency medicine. Presentation with intraabdominal hemorrhage is associated with a high mortality rate. Case report: We report the case of an adult male, referred for a severe acute pain in the left lower chest-upper quadrant abdomen pain. We present multislice contrast-enhanced CT-scanning and angiographic findings, and a life-saving emergency trancatheter embolization, using fragments of absorbable gelatin sponge. Emergency doctors should consider ruptured hepatic artery aneurysms in the differential diagnosis of acute abdominal pain and promptly cooperate with endovascular specialists to treat this life-threatening condition.

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