scholarly journals Regulation of inflammation, antioxidant production, and methyl-carbon metabolism during methionine supplementation in lipopolysaccharide-challenged neonatal bovine hepatocytes

2017 ◽  
Vol 100 (10) ◽  
pp. 8565-8577 ◽  
Author(s):  
Qian Zhang ◽  
Heather M. White
2010 ◽  
Vol 80 (45) ◽  
pp. 319-329 ◽  
Author(s):  
Allyson A. West ◽  
Marie A. Caudill

Folate and choline are water-soluble micronutrients that serve as methyl donors in the conversion of homocysteine to methionine. Inadequacy of these nutrients can disturb one-carbon metabolism as evidenced by alterations in circulating folate and/or plasma homocysteine. Among common genetic variants that reside in genes regulating folate absorptive and metabolic processes, homozygosity for the MTHFR 677C > T variant has consistently been shown to have robust effects on status markers. This paper will review the impact of genetic variants in folate-metabolizing genes on folate and choline bioefficacy. Nutrient-gene and gene-gene interactions will be considered along with the need to account for these genetic variants when updating dietary folate and choline recommendations.


1994 ◽  
Vol 111 ◽  
pp. 245-255 ◽  
Author(s):  
E Kristensen ◽  
GM King ◽  
M Holmer ◽  
GT Banta ◽  
MH Jensen ◽  
...  

1959 ◽  
Vol 18 (3) ◽  
pp. 1053-1058 ◽  
Author(s):  
D. C. Acker ◽  
D. V. Catron ◽  
V. W. Hays

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