Radiographic and clinical outcomes in one- and two-level transforaminal lumbar interbody fusions: a comparison of bullet versus banana cages

2021 ◽  
pp. 1-10
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Transforaminal Lumbar Interbody Fusion ◽  
Reciprocal Relationship ◽  
Adjacent Segment ◽  
Disc Space ◽  
Patient Reported ◽  
Index Level ◽  
Segmental Lordosis ◽  
Reoperation Rates

OBJECTIVE The aim of this study was to determine whether cage morphology influences clinical and radiographic outcomes following short-segment transforaminal lumbar interbody fusion (TLIF) procedures. METHODS The authors retrospectively reviewed one- and two-level TLIFs at a single tertiary care center between August 2012 and November 2019 with a minimum 1-year radiographic and clinical follow-up. Two cohorts were compared based on interbody cage morphology: steerable “banana” cage or straight “bullet” cage. Patient-reported outcome measures (PROMs), radiographs, and complications were analyzed. RESULTS A total of 135 patients with 177 interbody levels were identified; 45 patients had 52 straight cages and 90 patients had 125 steerable cages. Segmental lordosis increased with steerable cages, while it decreased with straight cages (+3.8 ± 4.6 vs −1.9 ± 4.3, p < 0.001). Conversely, the mean segmental lordosis of adjacent lumbar levels decreased in the former group, while it increased in the latter group (−0.52 ± 1.9 vs +0.52 ± 2.1, p = 0.004). This reciprocal relationship results in global sagittal parameters, including pelvic incidence minus lumbar lordosis and lumbar distribution index, which did not change after surgery with either cage morphology. Multivariate analysis confirmed that steerable cage morphology, anterior cage positioning, and less preoperative index-level segmental lordosis were associated with greater improvement in index-level segmental lordosis. PROMs were improved after surgery with both cage types, and the degree of improvement did not differ between cohorts (p > 0.05). Perioperative and radiographic complications were similar between cohorts (p > 0.05). Overall reoperation rates, as well as reoperation rates for adjacent-segment disease within 2 years of surgery, were not significantly different between cohorts. CONCLUSIONS Steerable cages are more likely to lie within the anterior disc space, thus increasing index-level segmental lordosis, which is accompanied by a reciprocal change in segmental alignment at the adjacent lumbar levels. The converse relationship occurs for straight cages, with a kyphotic change at the index levels and reciprocal lordosis occurring at adjacent levels.

scholarly journals A Comparison of Revision Rates and Patient-Reported Outcomes for a 2-Level Posterolateral Fusion Augmented With Single Versus 2-Level Transforaminal Lumbar Interbody Fusion

2019 ◽  
Vol 10 (8) ◽  
pp. 958-963
Author(s):  
I. David Kaye ◽  
Terry Fang ◽  
Scott C. Wagner ◽  
Joseph S. Butler ◽  
Arjun Sebastian ◽  
...  
Keyword(s):  
Interbody Fusion ◽  
Transforaminal Lumbar Interbody Fusion ◽  
Adjacent Segment Disease ◽  
Posterolateral Fusion ◽  
Adjacent Segment ◽  
Lumbar Interbody Fusion ◽  
Control Series ◽  
Patient Reported ◽  
Reoperation Rates ◽  
Level Group

Study Design: Retrospective, single institution, multisurgeon case control series. Objective: To determine whether there are differences in reoperation rates or outcomes for patients undergoing 2-level posterolateral fusion (PLF) augmented by a transforaminal lumbar interbody fusion (TLIF) at only one of the levels or at both. Methods: A total of 416 patients were identified who underwent 2-level PLF with a TLIF at either one of those levels (n = 183) or at both (n = 233) with greater than 1-year follow-up. Demographic, surgical, radiographic, and clinical data was reviewed for each patient. These included age, sex, race, body mass index, smoking status, Charleston Comorbidity Index, operative time, estimated blood loss, length of stay, and patient-reported outcome measures. Results: Each cohort underwent 24 reoperations. Although the number of overall reoperations was not significantly different ( P > .05), among the reoperation types, there were significantly more reoperations for adjacent segment disease in the 2-level group compared to the 1-level group (19 vs 12, P = .04). There was no difference in reoperation for pseudarthrosis between the groups ( P > .05). Although both groups experienced significant improvements in Oswestry Disability Index ( P < .001) and Short Form–12 health questionnaire ( P < .001), there were no differences between improvements for 1- versus 2-level cohorts. Conclusions: For patients undergoing 2-level PLF in the setting of a TLIF, using a TLIF at one versus both levels does not seem to influence reoperation rates or outcomes. However, reoperation rates for adjacent segment disease are increased in the setting of a 2-level PLF augmented by a 2-level TLIF.

scholarly journals Minimally invasive transforaminal lumbar interbody fusion with expandable versus static interbody devices: radiographic assessment of sagittal segmental and pelvic parameters

2017 ◽  
Vol 43 (2) ◽  
pp. E10 ◽  
Author(s):  
Ammar H. Hawasli ◽  
Jawad M. Khalifeh ◽  
Ajay Chatrath ◽  
Chester K. Yarbrough ◽  
Wilson Z. Ray
Keyword(s):  
Lumbar Lordosis ◽  
Pelvic Incidence ◽  
Transforaminal Lumbar Interbody Fusion ◽  
Disc Height ◽  
Disc Space ◽  
Pelvic Parameters ◽  
Radiographic Measurements ◽  
Index Level ◽  
Segmental Lordosis ◽  
Foraminal Height

OBJECTIVEMinimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has been adopted as an alternative technique to hasten recovery and minimize postoperative morbidity. Advances in instrumentation technologies and operative techniques have evolved to maximize patient outcomes as well as radiographic results. The development of expandable interbody devices allows a surgeon to perform MIS-TLIF with minimal tissue disruption. However, sagittal segmental and pelvic radiographic outcomes after MIS-TLIF with expandable interbody devices are not well characterized. The object of this study is to evaluate the radiographic sagittal lumbar segmental and pelvic parameter outcomes of MIS-TLIF performed using an expandable interbody device.METHODSA retrospective review of MIS-TLIFs performed between 2014 and 2016 at a high-volume center was performed. Radiographic measurements were performed on lateral radiographs before and after MIS-TLIF with static or expandable interbody devices. Radiographic measurements included disc height, foraminal height, fused disc angle, lumbar lordosis, pelvic incidence, sacral slope, and pelvic tilt. Mismatch between pelvic incidence and lumbar lordosis were calculated for each radiograph.RESULTSA total of 48 MIS-TLIFs were performed, predominantly at the L4–5 level, in 44 patients. MIS-TLIF with an expandable interbody device led to a greater and more sustained increase in disc height when compared with static interbody devices. Foraminal height increased after MIS-TLIF with expandable but not with static interbody devices. MIS-TLIF with expandable interbody devices increased index-level segmental lordosis more than with static interbody devices. The increase in segmental lordosis was sustained in the patients with expandable interbody devices but not in patients with static interbody devices. For patients with a collapsed disc space, MIS-TLIF with an expandable interbody device provided superior and longer-lasting increases in disc height, foraminal height, and index-level segmental lordosis than in comparison with patients with static interbody devices. Using an expandable interbody device improved the Oswestry Disability Index scores more than using a static interbody device, and both disc height and segmental lordosis were correlated with improved clinical outcome. Lumbar MIS-TLIF with expandable or static interbody devices had no effect on overall lumbar lordosis, pelvic parameters, or pelvic incidence–lumbar lordosis mismatch.CONCLUSIONSPerforming MIS-TLIF with an expandable interbody device led to a greater and longer-lasting restoration of disc height, foraminal height, and index-level segmental lordosis than MIS-TLIF with a static interbody device, especially for patients with a collapsed disc space. However, neither technique had any effect on radiographic pelvic parameters.

scholarly journals Suicidal risk and resilience in juvenile fibromyalgia syndrome: a cross-sectional cohort study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sabrina Gmuca ◽  
Maitry Sonagra ◽  
Rui Xiao ◽  
Kimberly S. Miller ◽  
Nina H. Thomas ◽  
...  
Keyword(s):  
Cohort Study ◽  
Suicidal Ideation ◽  
Fibromyalgia Syndrome ◽  
Care Center ◽  
Tertiary Care ◽  
Pain Clinic ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
Juvenile Fibromyalgia ◽  
Patient Reported

Abstract Background To characterize suicidality among youth with juvenile fibromyalgia syndrome (JFMS) receiving treatment from pediatric rheumatologists at a tertiary care center in order to determine the prevalence of suicidality in JFMS and to explore risk factors for persistent suicidal ideation. Methods We performed a cross-sectional cohort study of children 12–17 years old with JFMS seen in a specialty pediatric rheumatology pain clinic from 7/2017–9/2019. All subjects completed patient-reported outcomes measures, complemented by retrospective chart review. Subjects who endorsed item 8 on the Children’s Depression Inventory, 2nd Edition (CDI-2) were categorized as endorsing suicidal ideation. We assessed for differences between the suicidal and non-suicidal patients using Wilcoxon-rank sum test. Logistic regression modeling was performed to identify psychosocial factors associated with suicidality. Results Of the 31 subjects, more than one-quarter endorsed suicidality. Nearly 90% of teens with suicidal ideation were established in outpatient counseling. In bivariate analyses, suicidality was associated with lower resilience and greater depression and anxiety (all p < 0.05). Pain intensity trended towards a statistically significant positive association (OR: 1.16 [0.99–1.37]; p = 0.06). Lower resilience was independently associated with suicidality (OR: 0.90 [95% CI: 0.82–0.98]; p < 0.02). Conclusions Suicidality was prevalent among youth with JFMS and persistent despite concurrent receipt of mental health services. Higher patient-level resilience was independently associated with a reduced odds of suicidality. Future work should examine the role of resilience training on reducing psychological distress and mitigating the risk of suicidality in JFMS.

Feasibility of Endoscopic Transforaminal Lumbar Interbody Fusion(eTLIF) through the Posterior Paraspinal Approach: Technical Note and Preliminary Result

2020 ◽  
Author(s):  
Hyeun-Sung Kim ◽  
Harshavardhan Dilip Raorane ◽  
Pang Hung Wu ◽  
Dong Hwa Heo ◽  
Yeon Jin Yi ◽  
...  
Keyword(s):  
Lumbar Lordosis ◽  
Interbody Fusion ◽  
Plain Radiograph ◽  
Transforaminal Lumbar Interbody Fusion ◽  
Disc Height ◽  
Lumbar Interbody Fusion ◽  
Disc Space ◽  
Paraspinal Approach ◽  
Segmental Lordosis

Abstract Background: Implementation of endoscopic spine surgery in the management of degenerative lumbar diseases has significantly reduced the need for fusion surgeries. The performance of a MIS-TLIF using an endoscope offers some distinct advantages, such as allowing better visualization the disc space, enhanced endplate preparation and contralateral decompression. The objective of this study was to analyze the preliminary clinical and radiological outcomes of the technique of endoscopic transforaminal lumbar interbody fusion (eTLIF).Materials and Methods: eighteen consecutive patients with degenerative lumbar disease underwent eTLIF through a conventional paraspinal approach. Their clinical outcomes were evaluated with visual analog scale(VAS) leg pain score, Oswestry Disability Index(ODI) and the MacNab's criteria; radiological outcome measured with segmental lordosis, global lumbar lordosis, disc height on plain radiograph and percentage of potential fusion mass on CT scan at pre-operative, post-operative and final follow up period. Intra operative and post-operative complications were noted.Results: Mean age was 63. 71 years and Mean follow-up periods was 7.78 months. In the X-ray result, mean segmental lordosis angle(SLA) improved in pre-operative/post-operative/follow-up period 9.87±2.74 degree/ 11.79±3.74 degree/ 10.56±3.69 degree (p > 0.01); mean lumbar lordosis angle(LLA) improved 37.1±7.04 degree/ 39.2±7.13 degree/ 35.7±7.25 degree (p > 0.01). Mean preoperative disc height(DH) improved from 8.97±1.49 mm/ 12.34±1.39 mm/ 11.44±1.98 mm (p < 0.01). In the CT result, Average percentage of fusion mass was 42.61%. VAS was improved significantly, 7.67±1.13 / 3.39±1.38 / 2.5±1.34 and ODI was improved significantly, 74.9±8.03/ 34.56±8.80 / 27.76±8.64 by each preoperative / postoperative / final follow-up. In the clinical result, excellent was 5 cases and good was 13 cases. Conclusion: According to the results of this study, endoscopic TLIF was feasible procedure with an advantage of better visualization and preservation of endplate, minimal blood loss and minimal post-operative pain with early mobilization. In addition, the fusion volume as measured on post-operative CT scans, occupied 40% to 50% of disc space along with the use of 3D printed cages expected to give higher fusion rates. In conclusion, our preliminary results show that endoscopic TLIF is considered to be a viable surgical procedure with further long-term follow-up warranted.

scholarly journals CHANGES IN THE LUMBAR VERTEBRAL SEGMENT RELATED TO THE CAGE POSITION IN TLIF TECHNIQUE

2020 ◽  
Vol 28 (2) ◽  
pp. 92-96
Author(s):  
THIAGO DANTAS MATOS ◽  
RODRIGO BARRA CAIADO FLEURY ◽  
KELSEN DE OLIVEIRA TEIXEIRA ◽  
VALÉRIA ROMERO ◽  
HELTON LUIZ APARECIDO DEFINO
Keyword(s):  
Interbody Fusion ◽  
Morphological Changes ◽  
Anterior Part ◽  
Transforaminal Lumbar Interbody Fusion ◽  
Intervertebral Foramen ◽  
Level Of Evidence ◽  
Disc Space ◽  
Therapeutic Study ◽  
Segmental Lordosis ◽  
Vertebral Segment

ABSTRACT Objective: To evaluate the morphological changes on the intervertebral foramen and segmental lordosis related to the transforaminal lumbar interbody fusion (TLIF) positioning. Methods: PEEK cages were placed in the disc space (L1-S1) of a polyurethane anatomical model. Cages of different heights (8 mm, 10 mm, 12 mm and 14 mm) were positioned in the posterior, medial or anterior part of the vertebral body surface, and the intervertebral foramen and segmental lordosis heights were measured after their insertion. Results: The vertebral foramen height decreased in all positions and heights of the cages in relation to the control. The cage posterior positioning induced a smaller reduction in the vertebral foramen height. Vertebral lordosis tended to increase in relation to the control, and the greatest increase occurred with the cage posterior positioning. Conclusion: Cage positioning induces changes in the intervertebral foramen height and in the vertebral segment lordosis. Cage posterior positioning induces a smaller reduction of the intervertebral foramen height and increases the vertebral segment lordosis. Level of evidence III, Therapeutic study.

The Impact of Laryngopharyngeal Reflux on Patient-reported Measures of Chronic Rhinosinusitis

2020 ◽  
Vol 129 (9) ◽  
pp. 886-893 ◽  
Author(s):  
Hannah J. Brown ◽  
Hannah N. Kuhar ◽  
Max A. Plitt ◽  
Inna Husain ◽  
Pete S. Batra ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Laryngopharyngeal Reflux ◽  
Care Center ◽  
Tertiary Care ◽  
Retrospective Chart Review ◽  
Reflux Symptom Index ◽  
Symptom Index ◽  
Patient Reported ◽  
The Impact ◽  
Snot 22

Objective: This study explored the impact of laryngopharyngeal reflux (LPR) on quality-of-life outcomes captured by Sino-Nasal Outcome Test (SNOT-22) and Reflux Symptom Index (RSI) in patients with chronic rhinosinusitis (CRS) and patients with symptoms of LPR. Methods: In a retrospective chart review, SNOT-22 and RSI scores were analyzed in patients seen at a tertiary care center with CRS, LPR, or both CRS and LPR. SNOT-22 items were grouped into sleep, nasal, otologic, and emotional symptom subdomains. Results: A total of 138 patients (36 with CRS alone, 60 with LPR alone, and 42 with both CRS and LPR) were included. Compared to patients with CRS alone, those with CRS and LPR (CRS+LPR) had higher SNOT-22 total (50.54 ± 19.53 vs 35.31 ± 20.20, P < .001), sleep (19.61 ± 9.31 vs 14.42 ± 10.34, P < .022), nasal (17.38 ± 7.49 vs 11.11 ± 8.52, P < .001), otologic subdomains (9.17 ± 5.07 vs 5.53 ± 5.14, P < .002), and RSI (22.06 ± 9.42 vs 10.75 ± 8.43, P < .003). Patients with LPR alone had higher RSI compared to those with CRS (18.48 ± 9.77 vs 10.75 ± 8.43, P < .037). RSI and SNOT-22 scores were positively correlated irrespective of patient group (R = 0.289, P = .003). Conclusion: Compared to patients with CRS or LPR alone, those with CRS+LPR demonstrated higher RSI and total and subdomain SNOT-22 scores. Patients with LPR alone had elevated SNOT-22 despite absent endoscopic evidence of sinusitis.

Preoperative Patient-Reported Outcomes May Help Predict Discharge Disposition after Total Hip Arthroplasty

2019 ◽  
Vol 03 (03) ◽  
pp. 136-141
Author(s):  
Raj Karia ◽  
David Novikov ◽  
Matthew Gotlin ◽  
James E. Feng ◽  
Afshin A. Anoushiravani ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Functional Status ◽  
Hip Arthroplasty ◽  
Care Center ◽  
Tertiary Care ◽  
Care Facility ◽  
Total Hip ◽  
Discharge Disposition ◽  
Lower Baseline ◽  
Patient Reported

AbstractPatient-reported outcome (PRO) instruments are measures that allow for a standardized assessment of a patient's functional status, symptoms, and quality of life (QoL) through self-reported questionnaires. The purpose of this study was to assess the relationship between PRO scores, which measure patients' preoperative pain and functional status, and discharge disposition in the total hip arthroplasty (THA) population. The authors conducted a retrospective review of patients with a primary diagnosis of osteoarthritis who underwent THA at a single, urban, tertiary care center between September 2013 and August 2016. Patient demographics and preoperative PRO scores (Hip Disability and Osteoarthritis Outcome Score [HOOS] and EuroQol 5-Dimension [EQ-5D] questionnaire) were collected, and discharge disposition was categorized into the following two cohorts: THA recipients discharged to home and those discharged to a postacute care facility. When comparing PRO scores between the two groups, patients discharged home were found to have significantly higher average preoperative global EQ-5D, EQ-5D-QoL, HOOS activities of daily living (ADL), HOOS pain, HOOS sports, and HOOS symptoms scores. Patients discharged home trended toward higher HOOS QoL scores (28.1 vs. 22.6%), but this did not achieve significance (p < 0.08). The authors found a significant relationship between patients' baseline PRO scores and discharge disposition following THA. Patients discharged home had significantly higher preoperative PRO scores as measured by EQ-5D and HOOS. This demonstrates that patients with lower baseline PRO scores, indicating lower baseline function, may require additional care following surgery. These scores provide surgeons with an objective parameter that can assist in the planning and coordination of postoperative care. This study was a level III retrospective cohort.

Pediatric-Onset Postural Orthostatic Tachycardia Syndrome in a Single Tertiary Care Center

2020 ◽  
Vol 35 (8) ◽  
pp. 526-535 ◽  
Author(s):  
Anthony Staples ◽  
Nicolas R. Thompson ◽  
Manikum Moodley
Keyword(s):  
Heart Rate ◽  
Orthostatic Intolerance ◽  
Care Center ◽  
Tertiary Care ◽  
Categorical Variables ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Presenting Symptoms ◽  
Unexplained Pain ◽  
Patient Reported ◽  
Pediatric Onset

Aim: We characterize the pediatric postural orthostatic tachycardia syndrome (POTS) population seen at a single tertiary care referral center. Method: Retrospective chart review of all pediatric POTS patients seen in our center between 2015 and 2017. Pediatric POTS was defined as chronic, at least 3 months, symptoms of orthostatic intolerance associated with excessive orthostatic tachycardia as determined by tilt table testing with orthostatic heart rate increment of ≥40 bpm within 5 minutes of head-up tilt or absolute orthostatic heart rate ≥130 bpm for patients 13 years old and younger and ≥120 bpm for those 14 years and older. We looked at demographics, presenting symptoms, comorbidities, examination findings, investigation findings, treatment, and patient reported outcomes. Outcome measures were separated by patient report and group comparisons were made using 2-sample t tests or Mann-Whitney U tests for continuous variables and Fisher exact tests for categorical variables. Results: One hundred thirty-four patients with pediatric onset POTS were identified. The mean age was 15 years. Seventy-nine percent of patients were female and 90% were white. The most common presenting symptoms included dizziness/lightheadedness (88%), syncope (54%), and palpitations (40%). Many patients had significant comorbidities attributable to numerous bodily systems, most commonly headache syndromes (migraine 43%, nonspecific headache 22%, chronic daily headache 14%, and new daily persistent headache 5%) and chronic fatigue (60%). Low vitamin D and insufficient iron stores were commonly seen. The majority of patients improved or had resolution of symptoms following treatment (70%). When separated by outcome, statistically significant differences were found for glucose (patients whose symptoms resolved had higher median glucose), palpitations (patients whose symptoms resolved were less likely to have palpitations), constipation (patients whose symptoms were stable/worsened were more likely to have constipation), and unexplained pain (patients whose symptoms were stable/worsened were more likely to have unexplained pain). Conclusions: Pediatric POTS is a chronic condition with a fairly good prognosis following appropriate treatment. It is associated with numerous comorbidities that necessitate multidisciplinary expert care.

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