Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resection

2003 ◽  
Vol 15 (5) ◽  
pp. 1-7 ◽  
Author(s):  
James K. Liu ◽  
Ronald I. Apfelbaum ◽  
Bennie W. Chiles ◽  
Meic H. Schmidt
Keyword(s):  
Cervical Spine ◽  
Spinal Metastasis ◽  
Posterior Instrumentation ◽  
Tumor Resection ◽  
Spinal Metastases ◽  
Metastatic Tumor ◽  
Subaxial Cervical Spine ◽  
Bone Autograft ◽  
Anterior Reconstruction ◽  
Anterior Cervical Corpectomy

Object In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods Reconstruction and stabilization of the cervical spine after vertebral body (VB) resection for metastatic tumor is an important goal in the surgical management of spinal metastasis. Generally, the VB defect is reconstructed with bone autograft or allograft, polymethylmethacrylate (PMMA), interbody spacers, and/or cages. In cases of PMMA-assisted reconstruction, internal devices are used to augment the fixation of PMMA. Stabilization is then achieved with anterior instrumentation, usually an anterior cervical locking plate. In some cases, posterior instrumentation may be necessary to supplement the anterior construct. Conclusions Anterior cervical corpectomy followed by reconstruction and stabilization is an effective strategy in the management of spinal metastases in patients.

scholarly journals Treatment of Injuries to the Subaxial Cervical Spine: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)

2018 ◽  
Vol 8 (2_suppl) ◽  
pp. 25S-33S ◽  
Author(s):  
Philipp Schleicher ◽  
Philipp Kobbe ◽  
Frank Kandziora ◽  
Matti Scholz ◽  
Andreas Badke ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cervical Spine ◽  
Facet Joint ◽  
Posterior Instrumentation ◽  
Pedicle Screws ◽  
German Society ◽  
Vertebral Body Replacement ◽  
Cervical Spine Injuries ◽  
Subaxial Cervical Spine ◽  
Spine Injuries

Study Design: Expert consensus. Objectives: To establish treatment recommendations for subaxial cervical spine injuries based on current literature and the knowledge of the Spine Section of the German Society for Orthopaedics and Trauma. Methods: This recommendation summarizes the knowledge of the Spine Section of the German Society for Orthopaedics and Trauma. Results: Therapeutic goals are a stable, painless cervical spine and protection against secondary neurologic damage while retaining maximum possible motion and spinal profile. The AOSpine classification for subaxial cervical injuries is recommended. The Canadian C-Spine Rule is recommended to decide on the need for imaging. Computed tomography is the favoured modality. Conventional x-ray is preserved for cases lacking a “dangerous mechanism of injury.” Magnetic resonance imaging is recommended in case of unexplained neurologic deficit, prior to closed reduction and to exclude disco-ligamentous injuries. Computed tomography angiography is recommended in high-grade facet joint injuries or in the presence of vertebra-basilar symptoms. A0-, A1- and A2-injuries are treated conservatively, but have to be monitored for progressive kyphosis. A3 injuries are operated in the majority of cases. A4- and B- and C-type injuries are treated surgically. Most injuries can be treated with anterior plate stabilization and interbody support; A4 fractures need vertebral body replacement. In certain cases, additive or pure posterior instrumentation is needed. Usually, lateral mass screws suffice. A navigation system is advised for pedicle screws from C3 to C6. Conclusions: These recommendations provide a framework for the treatment of subaxial cervical spine Injuries. They give advice about diagnostic measures and the therapeutic strategy.

Single-stage posterior vertebrectomy and replacement combined with posterior instrumentation for spinal metastasis

1996 ◽  
Vol 85 (2) ◽  
pp. 211-220 ◽  
Author(s):  
Edward W. Akeyson ◽  
Ian E. McCutcheon
Keyword(s):  
Vertebral Body ◽  
Spinal Metastasis ◽  
Posterior Instrumentation ◽  
Thoracolumbar Spine ◽  
Spinal Metastases ◽  
Radical Resection ◽  
Single Stage ◽  
Surgical Approaches ◽  
Graft Material ◽  
Content Type

✓ The authors present a series of 25 patients who underwent single-stage complete spondylectomy, vertebral body reconstruction, and posterior segmental spinal stabilization for malignant metastatic disease involving multiple columns of the thoracolumbar spine. Patients were selected for this approach primarily because they were poor candidates for a transcavitary or lateral extracavitary approach or because the tumor involved both anterior and posterior columns of the spine. The operative approach used combines radical local resection of tumor via a bilateral transpedicular route, methylmethacrylate vertebral body reconstruction, and Luque rectangle stabilization in a single operation. Following surgery, the majority of patients experienced improvement in their neurological status, reduction in pain, or both. Most patients were functionally improved, or at least no worse, and spinal alignment was maintained in all. There was one local recurrence in a long-term survivor. Complications included cerebrospinal fluid fistulas, migrating graft material, and wound healing problems. The authors conclude that this surgical approach is safe and feasible for the radical resection of vertebral metastasis when combined with reconstruction and stabilization. This technique represents a useful alternative to other commonly used surgical approaches for the treatment of spinal metastases, and it should aid surgeons in selecting the optimum approach for individual patients.

Titanium Cage-assisted Polymethylmethacrylate Reconstruction for Cervical Spinal Metastasis: Technical Note

2005 ◽  
Vol 56 (suppl_1) ◽  
pp. ONS-E207-ONS-E207 ◽  
Author(s):  
James K. Liu ◽  
William S. Rosenberg ◽  
Meic H. Schmidt
Keyword(s):  
Cervical Spine ◽  
Spinal Metastasis ◽  
Plate Fixation ◽  
Body Height ◽  
Tumor Resection ◽  
Reconstruction Technique ◽  
Titanium Cage ◽  
Postoperative Hematoma ◽  
Cervical Plate ◽  
Anterior Cervical Plate

Abstract OBJECTIVE: Reconstruction and stabilization of the cervical spine after vertebrectomy is an important goal in the surgical management of spinal metastasis. The authors describe their reconstruction technique using a titanium cage-Silastic tube construct injected with polymethylmethacrylate (PMMA) augmented by an anterior cervical plate. The surgical results using this technique are reviewed. METHODS: Six patients ranging from 43 to 70 years of age underwent resection of metastatic tumor in the cervical spine followed by cage-assisted PMMA reconstruction of the anterior spinal column. The following reconstruction technique was performed. A Silastic tube is incised longitudinally and placed circumferentially around a titanium cage with the opening facing anteriorly. The cage-Silastic tube construct is carefully tapped into the corpectomy defect and filled with PMMA. The final construct is then augmented with anterior cervical plate fixation. RESULTS: Two patients required additional posterior stabilization with lateral mass screws and rods. All patients achieved immediate stabilization, restoration of vertebral body height and normal lordosis, and preservation of the ability to walk independently. Five patients experienced significant palliation of biomechanical neck pain. There were no complications of neurological worsening, postoperative hematoma, wound infection, subsidence, graft dislodgement, or construct failure during a follow-up period of 1 to 19 months (mean, 6.8 mo). CONCLUSION: Titanium cage-assisted PMMA reconstruction augmented with an anterior cervical plate is an effective means of reconstruction after tumor resection in patients with cervical spinal metastasis. The Silastic tube holds the PMMA within the cage and protects the spinal cord from potential thermal injury.

scholarly journals Cortical bone facet spacers for cervical spine decompression: effects on intervertebral kinetics and foraminal area

2016 ◽  
Vol 24 (1) ◽  
pp. 69-76 ◽  
Author(s):  
Christopher M. Maulucci ◽  
Charles A. Sansur ◽  
Vaneet Singh ◽  
Alexandra Cholewczynski ◽  
Snehal S. Shetye ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Cortical Bone ◽  
Posterior Instrumentation ◽  
Principal Component ◽  
Biomechanical Study ◽  
Nerve Roots ◽  
En Bloc ◽  
Cross Sectional ◽  
Subaxial Cervical Spine ◽  
Foraminal Area

OBJECT Nerve root decompression to relieve pain and radiculopathy remains one of the main goals of fusion-promoting procedures in the subaxial cervical spine. The use of allograft facet spacers has been suggested as a potential alternative for performing foraminotomies to increase the space available for the cervical nerve roots while providing segmental stiffening. Therefore, the goal of this cadaveric biomechanical study was to determine the acute changes in kinetics and foraminal area after the insertion of cortical bone facet spacers into the subaxial cervical spine. METHODS Allograft spacers (2 mm in height) were placed bilaterally into cadaveric cervical spine specimens (C2-T1, age of donors 57.5 ± 9.5 years, n = 7) at 1 (C4–5) and 3 (C3–6) levels with and without laminectomies and posterior lateral mass screw fixation. Standard stereophotogrammetry under pure moment loading was used to assess spinal kinetics. In addition, the authors performed 3D principal component analysis of CT scans to determine changes in foraminal cross-sectional area (FCSA) available for the spinal nerve roots. RESULTS Generally, the introduction of 2-mm-height facet spacers to the cervical spine produced mild, statistically insignificant reductions in motion with particular exceptions at the levels of implantation. No significant adjacent-level motion effects in any bending plane were observed. The addition of the posterior instrumentation (PI) to the intact spines resulted in statistically significant reductions in motion at all cervical levels and bending planes. The same kinetic results were obtained when PI was added to spines that also had facet spacers at 3 levels and spines that had been destabilized by en bloc laminectomy. The addition of 2-mm facet spacers at C3–4, C4–5, and C5–6 did produce statistically significant increases in FCSA at those levels. CONCLUSIONS The addition of allograft cervical facet spacers should be considered a potential option to accomplish indirect foraminal decompression as measured in this cadaveric biomechanical study. However, 2-mm spacers without supplemental instrumentation do not provide significantly increased spinal segmental stability.

scholarly journals Transthoracic vertebrectomy for metastatic spinal tumors

1998 ◽  
Vol 5 (2) ◽  
pp. E2 ◽  
Author(s):  
Ziya L. Gokaslan ◽  
Julie E. York ◽  
Garrett L. Walsh ◽  
Ian E. McCutcheon ◽  
Frederick F. Lang ◽  
...  
Keyword(s):  
Spinal Metastasis ◽  
Posterior Instrumentation ◽  
Spinal Metastases ◽  
Neurological Dysfunction ◽  
Spinal Tumors ◽  
Cancer Center ◽  
Primary Tumors ◽  
Entire Study ◽  
Lower Extremity Weakness ◽  
Presenting Symptoms

Anterior approaches to the spine for the treatment of spinal tumors have gained acceptance; however, in most published reports, patients with primary, metastatic, or chest wall tumors involving cervical, thoracic, or lumbar regions of the spine are combined. The purpose of this study was to provide a clear perspective of results that can be expected in patients who undergo anterior vertebral body resection, reconstruction, and stabilization for spinal metastases that are limited to the thoracic region. Outcome is presented for 72 patients with metastatic spinal tumors who were treated by transthoracic vertebrectomy at The University of Texas M. D. Anderson Cancer Center. The predominant primary tumors included renal cancer in 19 patients, breast cancer in 10, melanoma or sarcoma in 10, and lung cancer in nine patients. The most common presenting symptoms were back pain, which occurred in 90% of patients, and lower-extremity weakness, which occurred in 64% of patients. All patients underwent transthoracic vertebrectomy, decompression, reconstruction with methylmethacrylate, and anterior fixation with locking plate and screw constructs. Supplemental posterior instrumentation was required in seven patients with disease involving the cervicothoracic or thoracolumbar junction, which was causing severe kyphosis. After surgery, pain improved in 60 of 65 patients. This improvement was found to be statistically significant (p < 0.001) based on visual analog scales and narcotic analgesic medication use. Thirty-five of the 46 patients who presented with neurological dysfunction improved significantly (p < 0.001) following the procedure. Thirty-three patients had weakness but could ambulate preoperatively. Seventeen of these 33 regained normal strength, 15 patients continued to have weakness, and one patient was neurologically worse postoperatively. Of the 13 preoperatively nonambulatory patients, 10 could walk after surgery and three were still unable to walk but showed improved motor function. Twenty-one patients had complications ranging from minor atelectasis to pulmonary embolism. The 30-day mortality rate was 3%. The 1-year survival rate for the entire study population was 62%. These results suggest that transthoracic vertebrectomy and spinal stabilization can improve the quality of life considerably in cancer patients with spinal metastasis by restoring or preserving ambulation and by controlling intractable spinal pain with acceptable rates of morbidity and mortality.

Intradural tumor recurrence after resection of extradural metastasis: a rare but potential complication of intraoperative durotomy

2014 ◽  
Vol 20 (6) ◽  
pp. 734-739 ◽  
Author(s):  
Manish K. Kasliwal ◽  
Lee A. Tan ◽  
John E. O'Toole
Keyword(s):  
Tumor Recurrence ◽  
Spinal Metastasis ◽  
Spinal Metastases ◽  
Intramedullary Tumor ◽  
Local Tumor ◽  
Local Tumor Recurrence ◽  
Tumor Dissemination ◽  
Intradural Tumor ◽  
Clinical Consequences ◽  
Clinical Awareness

Spinal metastases are the most common of spinal neoplasms and occur predominantly in an extradural location. Their appearance in an intradural location is uncommon and is associated with a poor prognosis. Cerebrospinal fluid dissemination accounts for a significant number of intradural spinal metastases mostly manifesting as leptomeningeal carcinomatoses or drop metastases from intracranial tumors. The occurrence of local tumor dissemination intradurally following surgery for an extradural spinal metastasis has not been reported previously. The authors describe 2 cases in which local intradural and intramedullary tumor recurrences occurred following resection of extradural metastases that were complicated by unintended durotomy. To heighten clinical awareness of this unusual form of local tumor recurrence, the authors discuss the possible etiology and clinical consequences of this entity.

A 3D-Printed Model-Assisted Cervical Spine Instrumentation after Tumor Resection in a 4-Year-Old Child: A Case Report

2021 ◽  
pp. 1-7
Author(s):  
Marko Jug
Keyword(s):  
Cervical Spine ◽  
3D Model ◽  
Intraoperative Complications ◽  
Tumor Resection ◽  
Upper Cervical Spine ◽  
Spine Instrumentation ◽  
Cord Injury ◽  
Spinal Navigation ◽  
Upper Cervical ◽  
3D Printed

<b><i>Introduction:</i></b> In the case of tumor resection in the upper cervical spine, a multilevel laminectomy with instrumented fixation is required to prevent kyphotic deformity and myelopathy. Nevertheless, instrumentation of the cervical spine in children under the age of 8 years is challenging due to anatomical considerations and unavailability of specific instrumentation. <b><i>Case Presentation:</i></b> We present a case of 3D-printed model-assisted cervical spine instrumentation in a 4-year-old child with post-laminectomy kyphotic decompensation of the cervical spine and spinal cord injury 1 year after medulloblastoma metastasis resection in the upper cervical spine. Due to unavailability of specific instrumentation, 3D virtual planning was used to assess and plan posterior cervical fixation. Fixation with 3.5 mm lateral mass and isthmic screws was suggested and the feasibility of fixation was confirmed “in vitro” in a 3D-printed model preoperatively to reduce the possibility of intraoperative implant-spine mismatch. Intraoperative conditions completely resembled the preoperative plan and 3.5 mm polyaxial screws were successfully used as planned. Postoperatively the child made a complete neurological recovery and 2 years after the instrumented fusion is still disease free with no signs of spinal decompensation. <b><i>Discussion/Conclusion:</i></b> Our case shows that posterior cervical fixation with the conventional screw-rod technique in a 4-year-old child is feasible, but we suggest that suitability and positioning of the chosen implants are preoperatively assessed in a printed 3D model. In addition, a printed 3D model offers the possibility to better visualize and sense spinal anatomy “in vivo,” thereby helping screw placement and reducing the chance for intraoperative complications, especially in the absence of intraoperative spinal navigation.

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