Selective radionecrosis of the choroid plexus for control of experimental hydrocephalus

1972 ◽  
Vol 36 (3) ◽  
pp. 270-275 ◽  
Author(s):  
Martin H. Weiss ◽  
Frank E. Nulsen ◽  
Benjamin Kaufman
Keyword(s):  
Cerebrospinal Fluid ◽  
Choroid Plexus ◽  
Intraventricular Pressure ◽  
Pathological Changes ◽  
Content Type ◽  
Cerebrospinal Fluid Flow ◽  
Experimental Hydrocephalus ◽  
Gamma Scanning ◽  
Diffuse Distribution ◽  
Fine Print

✓ Hydrocephalic dogs treated with intraventricular radioactive colloidal gold showed a sustained decrease in cerebrospinal fluid flow and intraventricular pressure associated with a reversal of progressive hydrocephalus. Gamma scanning and isotopic sampling, however, indicated a more diffuse distribution of the isotope than previously thought, although pathological changes up to 7 weeks post-instillation of the radioactive colloid appeared confined to the choroid plexus.

Surgical removal of bilateral papillomas of the choroid plexus of the lateral ventricles with resolution of hydrocephalus

1979 ◽  
Vol 50 (5) ◽  
pp. 677-681 ◽  
Author(s):  
Steven K. Gudeman ◽  
Humbert G. Sullivan ◽  
Michael J. Rosner ◽  
Donald P. Becker
Keyword(s):  
Cerebrospinal Fluid ◽  
Choroid Plexus ◽  
Large Volume ◽  
Surgical Removal ◽  
Tumor Removal ◽  
Content Type ◽  
Lateral Ventricles ◽  
Csf Diversion ◽  
Csf Production ◽  
Fine Print

✓ The authors report a patient with bilateral papillomas of the choroid plexus of the lateral ventricles with documentation of cerebrospinal fluid (CSF) hypersecretion causing hydrocephalus. Special attention is given to the large volume of CSF produced by these tumors (removal of one tumor reduced CSF outflow by one-half) and to the fact that CSF diversion was not required after both tumors were removed. Since tumor removal alone was sufficient to stop the progression of hydrocephalus, we feel that this case supports the concept that elevated CSF production by itself is sufficient to cause hydrocephalus in patients with papillomas of the choroid plexus.

Management of proximal shunt obstruction

1988 ◽  
Vol 68 (5) ◽  
pp. 817-819 ◽  
Author(s):  
Charles C. Duncan
Keyword(s):  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Intracranial Pressure ◽  
Signs And Symptoms ◽  
Ventricular Catheter ◽  
Shunt Failure ◽  
Content Type ◽  
Cerebrospinal Fluid Flow ◽  
Shunt Obstruction ◽  
Fine Print

✓ Proximal shunt obstruction or obstruction of the ventricular catheter may present with signs and symptoms of shunt failure with either no cerebrospinal fluid flow or a falsely low intracranial pressure (ICP) upon shunt tap. The author reports a technique for lowering the ICP and for measuring the pressure in patients with such obstruction by cannulation of the reservoir and ventricular catheter to penetrate into the ventricle with a 3½-in. No. 22 spinal needle. The findings in 20 cases in which this approach was utilized are summarized.

Primary spinal syringomyelia

2005 ◽  
Vol 3 (6) ◽  
pp. 429-435 ◽  
Author(s):  
Ulrich Batzdorf
Keyword(s):  
Spinal Cord ◽  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Craniovertebral Junction ◽  
Arachnoid Cysts ◽  
Spinal Cord Tumors ◽  
Content Type ◽  
Cerebrospinal Fluid Flow ◽  
Different Types ◽  
Fine Print

✓ In the present review the author describes the different types of syringomyelia that originate from abnormalities at the level of the spinal cord rather than at the craniovertebral junction. These include posttraumatic and postinflammatory syringomyelia, as well as syringomyelia associated with arachnoid cysts and spinal cord tumors. The diagnosis and the principles of managing these lesions are discussed, notably resection of the entity restricting cerebrospinal fluid flow. Placement of a shunt into the syrinx cavity is reserved for patients in whom other procedures have failed or who are not candidates for other procedures.

Formation of cerebrospinal fluid

1975 ◽  
Vol 42 (6) ◽  
pp. 665-673 ◽  
Author(s):  
Michael Pollay
Keyword(s):  
Cerebrospinal Fluid ◽  
Choroid Plexus ◽  
Water Flow ◽  
Structural Basis ◽  
Content Type ◽  
Flux Chambers ◽  
Fine Print

✓ After a brief summary of current views on the origin of cerebrospinal fluid (CSF) and the processes underlying its elaboration, the author discusses studies of isolated choroid plexus in extracorporeal perfusion systems and flux chambers. The results suggest that transependymal water flow is secondary to the electrically silent pumping of sodium. The author presents evidence in support of the standing gradient hypothesis as the structural basis of CSF secretion.

Audible cerebrospinal fluid flow through a ventriculoperitoneal shunt

1987 ◽  
Vol 67 (3) ◽  
pp. 460-462 ◽  
Author(s):  
Joe I. Ordia ◽  
Ronald W. Mortara ◽  
Edward L. Spatz
Keyword(s):  
Cerebrospinal Fluid ◽  
Fluid Flow ◽  
Ventriculoperitoneal Shunt ◽  
Content Type ◽  
Cerebrospinal Fluid Flow ◽  
Ventriculoperitoneal Shunting ◽  
Flow Through ◽  
Fine Print

✓ An audible, noisy cerebrospinal fluid flow is an uncommon sequela of ventriculoperitoneal shunting. Two cases presenting this phenomenon are described.

Hydrocephalus due to villous hypertrophy of the choroid plexus in the lateral ventricles

1994 ◽  
Vol 80 (2) ◽  
pp. 321-323 ◽  
Author(s):  
Hirofumi Hirano ◽  
Kazuho Hirahara ◽  
Tetsuhiko Asakura ◽  
Tetsuro Shimozuru ◽  
Koki Kadota ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Mental Retardation ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Choroid Plexus ◽  
Ventriculoperitoneal Shunt ◽  
Rare Case ◽  
Content Type ◽  
Lateral Ventricles ◽  
Fine Print

✓ A case is reported of hydrocephalus due to overproduction of cerebrospinal fluid (CSF) caused by villous hypertrophy of the choroid plexus in the lateral ventricles. A 7-year-old girl with mental retardation developed gait disturbance; hydrocephalus and a Dandy-Walker cyst were detected on computerized tomography. She was initially treated with a ventriculoperitoneal shunt; however, shunting failed to control the hydrocephalus. The excessive outflow of CSF suggested choroid plexus abnormality, and magnetic resonance (MR) imaging revealed enlargement of the choroid plexus in both lateral ventricles. The patient was therefore diagnosed as having hydrocephalus induced by overproduction of CSF, which was controlled by resection of the choroid plexus. Histological examination showed the structure typical of normal choroid plexus. This is a rare case of villous hypertrophy of the choroid plexus in which MR imaging assisted in the diagnosis.

The relationship of compensated to decompensated hydrocephalus in the cat

1973 ◽  
Vol 39 (6) ◽  
pp. 694-697 ◽  
Author(s):  
Gerald M. Hochwald ◽  
Fred Epstein ◽  
Chaman Malhan ◽  
Joseph Ransohoff
Keyword(s):  
Cerebrospinal Fluid ◽  
Steady State ◽  
Ventricular Volume ◽  
Content Type ◽  
Experimental Hydrocephalus ◽  
Intracisternal Injection ◽  
Adult Cats ◽  
Relationship Of ◽  
The Relationship ◽  
Fine Print

✓ The effects of removal of the calvaria and excision of the dura on the development of hydrocephalus was studied in adult cats made hydrocephalic by an intracisternal injection of kaolin. In some animals, the calvaria was removed prior to the induction of experimental hydrocephalus, and in others when the hydrocephalus was compensated. In both groups of cats, the results were similar. Ventricular dilatation was massive, often leaving a cortical mantle less than 1 mm thick. A mean ventricular volume measured in 17 cats was 16.9 ml. Cerebrospinal fluid turnover measured during steady-state ventricular perfusion showed significant increases in formation and decreases in absorption of spinal fluid when compared to that in hydrocephalic cats with intact skulls.

Variations of intraventricular pressure during pneumoencephalography

1974 ◽  
Vol 40 (1) ◽  
pp. 101-106 ◽  
Author(s):  
Jacques Philippon ◽  
Bernard George ◽  
Jean Metzger
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Hypertension ◽  
Normal Pressure Hydrocephalus ◽  
Initial Pressure ◽  
Normal Pressure ◽  
Intraventricular Pressure ◽  
Csf Dynamics ◽  
Content Type ◽  
Fine Print

✓ Intraventricular pressure was studied in eight patients during and after diagnostic pneumoencephalography. In cases with normal initial pressure and normal cerebrospinal fluid (CSF) dynamics, variations in pressure were moderate, immediate, and disappeared at the end of the examination. In cases of normal-pressure hydrocephalus, there was a slow but relatively important elevation that continued for at least 24 hours. In cases with intracranial hypertension, there was a rapid significant increase; return to normal depended principally upon the flow from a large CSF compartment.

Hydrocephalus secondary to diffuse villous hyperplasia of the choroid plexus

1996 ◽  
Vol 85 (4) ◽  
pp. 689-691 ◽  
Author(s):  
Gavin W. Britz ◽  
D. Kyle Kim ◽  
John D. Loeser
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebrospinal Fluid ◽  
Choroid Plexus ◽  
Resonance Imaging ◽  
Ventriculoatrial Shunt ◽  
Content Type ◽  
Tomography Scanning ◽  
Csf Production ◽  
Choroid Plexus Papillomas ◽  
Fine Print

✓ Diffuse villous hyperplasia of the choroid plexus, which is distinct from bilateral choroid plexus papillomas, is extremely rare and is often associated with hydrocephalus due to the overproduction of cerebrospinal fluid (CSF). The authors describe an infant with hydrocephalus, diagnosed by computerized tomography scanning, who developed ascites following placement of a ventriculoperitoneal shunt and, subsequently, demonstrated excessive CSF production when the shunt was externalized. The patient was later successfully treated by placement of a ventriculoatrial shunt. Magnetic resonance imaging demonstrated diffuse villous hyperplasia of the choroid plexus as the cause of the patient's hydrocephalus. The literature on diffuse villous hyperplasia of the choroid plexus is reviewed.

Intracranial pressure and conductance to outflow of cerebrospinal fluid in normal-pressure hydrocephalus

1979 ◽  
Vol 50 (4) ◽  
pp. 489-493 ◽  
Author(s):  
Svend Erik Børgesen ◽  
Flemming Gjerris ◽  
Søren Claus Sørensen
Keyword(s):  
Cerebrospinal Fluid ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Intraventricular Pressure ◽  
Content Type ◽  
Normal Limits ◽  
Selection Of Patients ◽  
Selection Of ◽  
Fine Print ◽  
High Conductance

✓ Forty patients with clinical evidence of normal-pressure hydrocephalus were studied by monitoring intraventricular pressure during a 24-hour period, and by a lumboventricular perfusion test for measurement of the conductance to outflow of cerebrospinal fluid (CSF). The purpose of the study was to investigate whether there is a relationship between intraventricular pressure and conductance to outflow of CSF, and whether it is possible to use the results from pressure monitoring in the selection of patients who may be expected to benefit from shunting therapy. The conductance to outflow was used as an evaluation factor in the selection of patients to be treated by a shunt. The conductance to CSF outflow differed by twelvefold between the lowest and highest values. The level of resting intraventricular pressure was within normal limits in all patients. Accordingly, there was no evidence of a relationship between conductance to outflow and intraventricular pressure. So-called B-waves were seen more frequently in patients with decreased conductance to outflow, but were also present in patients with high conductance to outflow. Therefore, the presence of B-waves does not imply a low conductance to outflow of CSF.

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