Intrasellar epidermoid cyst

1983 ◽  
Vol 58 (3) ◽  
pp. 411-415 ◽  
Author(s):  
James E. Boggan ◽  
Richard L. Davis ◽  
Greg Zorman ◽  
Charles B. Wilson
Keyword(s):  
Pituitary Adenoma ◽  
Epidermoid Cyst ◽  
Cystic Lesions ◽  
Sellar Region ◽  
Content Type ◽  
Fine Print

✓ The authors report the uncomplicated removal of an intrasellar epidermoid cyst that on presentation mimicked a pituitary adenoma. Current controversies regarding the differentiation of this cyst from other cystic lesions of the sellar region are reviewed.

Intrasellar chordomas mimicking pituitary adenoma

2000 ◽  
Vol 92 (6) ◽  
pp. 976-982 ◽  
Author(s):  
Eleni Thodou ◽  
George Kontogeorgos ◽  
Bernd W. Scheithauer ◽  
Ioanna Lekka ◽  
Spyros Tzanis ◽  
...  
Keyword(s):  
Pituitary Adenoma ◽  
Dna Analysis ◽  
Sellar Region ◽  
Limited Extent ◽  
Pituitary Fossa ◽  
Content Type ◽  
Favorable Prognosis ◽  
Clinicopathological Study ◽  
Proper Diagnosis ◽  
Fine Print

Object. Whereas chordomas involving the sellar region are uncommon, largely or entirely intrasellar examples are rare. The goal in this study was to present examples of these rare tumors as a guide to their proper diagnosis and treatment.Methods. The authors report three cases in which the chordomas filled the pituitary fossa and presented as nonfunctioning pituitary adenomas. All lesions exhibited the typical histological patterns and immunophenotype of chordoma. One tumor, studied ultrastructurally and subjected to DNA analysis, was shown to have a diploid histogram. The authors present a clinicopathological study of these three cases and review the literature on intrasellar chordomas.Conclusions. Although these tumors are easily misdiagnosed and therefore may not receive optimal treatment, aggressive surgical resection can yield a favorable prognosis in lesions with a limited extent.

Pituitary adenoma producing growth hormone and adrenocorticotropin: a histological, immunocytochemical, electron microscopic, and in situ hybridization study

1998 ◽  
Vol 88 (6) ◽  
pp. 1111-1115 ◽  
Author(s):  
Kalman Kovacs ◽  
Eva Horvath ◽  
Lucia Stefaneanu ◽  
Juan Bilbao ◽  
William Singer ◽  
...  
Keyword(s):  
Growth Hormone ◽  
In Situ Hybridization ◽  
Pituitary Adenoma ◽  
Immunoelectron Microscopy ◽  
Secretory Granules ◽  
Cell Types ◽  
Content Type ◽  
Separate Cell ◽  
Fine Print

✓ The authors report on the morphological features of a pituitary adenoma that produced growth hormone (GH) and adrenocorticotropic hormone (ACTH). This hormone combination produced by a single adenoma is extremely rare; a review of the available literature showed that only one previous case has been published. The tumor, which was removed from a 62-year-old man with acromegaly, was studied by histological and immunocytochemical analyses, transmission electron microscopy, immunoelectron microscopy, and in situ hybridization. When the authors used light microscopy, the tumor appeared to be a bimorphous mixed pituitary adenoma composed of two separate cell types: one cell population synthesized GH and the other ACTH. The cytogenesis of pituitary adenomas that produce more than one hormone is obscure. It may be that two separate cells—one somatotroph and one corticotroph—transformed into neoplastic cells, or that the adenoma arose in a common stem cell that differentiated into two separate cell types. In this case immunoelectron microscopy conclusively demonstrated ACTH in the secretory granules of several somatotrophs. This was associated with a change in the morphological characteristics of secretory granules. Thus it is possible that the tumor was originally a somatotropic adenoma that began to produce ACTH as a result of mutations that occurred during tumor progression.

Intradiploic epidermoid cyst of the occipital bone with torcular obstruction

1978 ◽  
Vol 48 (3) ◽  
pp. 475-478 ◽  
Author(s):  
Setti Rengachary ◽  
Pulla R. S. Kishore ◽  
Itaru Watanabe
Keyword(s):  
Posterior Fossa ◽  
Epidermoid Cyst ◽  
Occipital Bone ◽  
Content Type ◽  
Fine Print

✓ The authors describe a patient with a giant occipital intradiploic epidermoid cyst with compression of the torcular and other posterior fossa structures.

Cushing's disease with pituitary apoplexy leading to hypopituitarism, empty sella, and spontaneous fracture of the dorsum sellae

1979 ◽  
Vol 51 (6) ◽  
pp. 866-869 ◽  
Author(s):  
Philip H. Gutin ◽  
William G. Cushard ◽  
Charles B. Wilson
Keyword(s):  
Pituitary Adenoma ◽  
Cushing’S Disease ◽  
Plasma Cortisol ◽  
Pituitary Apoplexy ◽  
Empty Sella ◽  
Cushing's Disease ◽  
Content Type ◽  
Urinary Levels ◽  
Fine Print ◽  
Transsphenoidal Resection

✓ A patient with a pituitary adenoma secreting adrenocorticotropin hormone manifested panhypopituitarism after an episode of pituitary apoplexy. The previously elevated urinary levels of 17-ketogenic steroids dropped sharply, and plasma cortisol became undetectable. The apoplexy also resulted in a partially empty sella on which the dorsum sellae collapsed. Recurrent Cushing's disease developed and was cured by transsphenoidal resection of a microadenoma.

Cerebellar metastasis from a prolactinoma during treatment with bromocriptine

1981 ◽  
Vol 55 (4) ◽  
pp. 615-619 ◽  
Author(s):  
Neil A. Martin ◽  
Martha Hales ◽  
Charles B. Wilson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pituitary Adenoma ◽  
Pituitary Tumors ◽  
Metastatic Tumor ◽  
Metastatic Spread ◽  
Content Type ◽  
The Central Nervous System ◽  
Cerebellar Metastasis ◽  
Fine Print

✓ A 31-year-old woman developed a cerebellar metastasis from an invasive prolactin-secreting pituitary adenoma while undergoing treatment with bromocriptine. The metastatic tumor was totally excised. Metastatic spread of pituitary tumors within the central nervous system is reviewed briefly.

Intracranial and intraspinal dissemination from a growth hormone-secreting pituitary tumor

1986 ◽  
Vol 64 (1) ◽  
pp. 140-144 ◽  
Author(s):  
Nobuo Hashimoto ◽  
Hajime Handa ◽  
Shogo Nishi
Keyword(s):  
Growth Hormone ◽  
Cerebrospinal Fluid ◽  
Radiation Therapy ◽  
Pituitary Adenoma ◽  
Pituitary Tumor ◽  
Invasive Growth ◽  
Metastatic Tumors ◽  
Content Type ◽  
Fine Print

✓ A 48-year-old woman developed multiple intracranial and intraspinal metastases from an invasive growth hormone-secreting pituitary adenoma after surgery and radiation therapy. This is the first reported case to show that the cells in the metastatic tumors and in the cerebrospinal fluid contained growth hormone.

Long-term control of recurrent cyst of the conus medullaris

1977 ◽  
Vol 47 (6) ◽  
pp. 953-954 ◽  
Author(s):  
Harold J. Hoffman ◽  
Renn O. Holness ◽  
Norman R. Flett
Keyword(s):  
Epidermoid Cyst ◽  
Conus Medullaris ◽  
Ommaya Reservoir ◽  
Content Type ◽  
Recurrent Cyst ◽  
Intermittent Drainage ◽  
Fine Print

✓ The authors report a case in which decompression of an intramedullary epidermoid cyst was maintained by intermittent drainage via an implanted subcutaneous Ommaya reservoir.

Rathke cleft cyst intracystic nodule: a characteristic magnetic resonance imaging finding

2005 ◽  
Vol 103 (5) ◽  
pp. 837-840 ◽  
Author(s):  
Mandy J. Binning ◽  
Oren N. Gottfried ◽  
Anne G. Osborn ◽  
William T. Couldwell
Keyword(s):  
Magnetic Resonance ◽  
Signal Intensity ◽  
Imaging Finding ◽  
Magnetic Resonance Imaging Finding ◽  
High Signal ◽  
Cystic Lesions ◽  
Mr Images ◽  
Content Type ◽  
Imaging Characteristics ◽  
Fine Print

Object. The fluid content of Rathke cleft cysts (RCCs) displays variable appearances on magnetic resonance (MR) images and can appear indistinguishable from other intrasellar or suprasellar cystic lesions. Intracystic nodules associated with individual RCCs have been noted, but to date their significance has not been fully explored. Methods. The authors retrospectively reviewed MR imaging studies obtained in patients harboring intrasellar or suprasellar lesions that were consistent with RCCs to identify the presence and imaging characteristics of intracystic nodules. An intracystic nodule was present in nine (45%) of 20 patients with an RCC. All intracystic nodules were clearly visible and displayed a characteristic low signal intensity on T2-weighted MR images. The nodule was only visualized on T1-weighted images in four cases, in which it exhibited a consistent high signal intensity similar to that of the cyst fluid. The nodules did not enhance following the intravenous administration of a contrast agent. Conclusions. Although it is difficult to differentiate RCCs from other sellar cystic lesions because of the variable signal intensities displayed on MR images, the intensity of the intracystic nodule seems consistent on T1- and T2-weighted images, and the nodule is always clearly visible on T2-weighted images. With a nonenhancing cystic lesion that does not cause significant symptoms in the patient, the identification of an intracystic nodule with a characteristic signal intensity will aid in the diagnosis of RCC and the selection of conservative management.

Intrasellar persistent trigeminal artery associated with a pituitary adenoma

1989 ◽  
Vol 70 (2) ◽  
pp. 271-273 ◽  
Author(s):  
K. Stuart Lee ◽  
David L. Kelly
Keyword(s):  
Pituitary Adenoma ◽  
Sella Turcica ◽  
Preoperative Imaging ◽  
Persistent Trigeminal Artery ◽  
Pituitary Macroadenoma ◽  
Trigeminal Artery ◽  
Imaging Studies ◽  
Content Type ◽  
Fine Print ◽  
Transsphenoidal Resection

✓ The case of a patient with Cushing's disease and a pituitary macroadenoma, who also had a persistent trigeminal artery coursing through the sella turcica on preoperative imaging studies, is presented. The patient was treated by transsphenoidal resection of the tumor.

Unusual CT-dense posterior fossa epidermoid cyst

1981 ◽  
Vol 55 (4) ◽  
pp. 654-656 ◽  
Author(s):  
Robert C. Dunn ◽  
Carol A. Archer ◽  
Richard L. Rapport ◽  
L. M. Looi
Keyword(s):  
Posterior Fossa ◽  
Epidermoid Cyst ◽  
Unusual Case ◽  
Content Type ◽  
Radiological Features ◽  
Fine Print

✓ A posterior fossa epidermoid cyst with high computerized tomographic attenuation is reported. The pathological and radiological features of this unusual case are presented.

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