Intrinsic brainstem choroid plexus papilloma

2004 ◽  
Vol 100 (6) ◽  
pp. 1076-1078 ◽  
Author(s):  
Ashok Pillai ◽  
Kariyattil Rajeev ◽  
Sushil Chandi ◽  
Muthukuttiparambil Unnikrishnan
Keyword(s):  
Central Nervous System ◽  
Choroid Plexus ◽  
Choroid Plexus Papilloma ◽  
Residual Tumor ◽  
Brainstem Lesion ◽  
Content Type ◽  
The Central Nervous System ◽  
Choroid Plexus Papillomas ◽  
Fine Print ◽  
Plexus Papilloma

✓ The authors report an intrinsic brainstem lesion that was diagnosed initially as a pontine cavernoma, which finally proved to be a choroid plexus papilloma. Choroid plexus papillomas are rare tumors of the central nervous system and are usually intraventricular in location. The occurrence of this tumor in an intraparenchymal location is extremely rare, and its occurrence within the brainstem is previously unreported. The authors also report a trial of chemotherapy with lomustine in the management of the residual tumor.

Malignant choroid plexus papilloma with extraneural metastasis

1980 ◽  
Vol 52 (2) ◽  
pp. 251-255 ◽  
Author(s):  
Joao B. Valladares ◽  
Robert H. Perry ◽  
Ramanand M. Kalbag
Keyword(s):  
Survival Time ◽  
Choroid Plexus ◽  
Lateral Ventricle ◽  
Choroid Plexus Papilloma ◽  
Content Type ◽  
Long Survival ◽  
Extraneural Metastasis ◽  
Fine Print ◽  
Plexus Papilloma

✓ The authors describe and discuss a case of malignant choroid plexus papilloma originating in the lateral ventricle of an 11-month-old child. Unusual features include a long survival time of 9 years and the presence of an extraneural malignant deposit, probably metastatic in origin.

Diffuse craniospinal seeding from a benign fourth ventricle choroid plexus papilloma

1998 ◽  
Vol 88 (4) ◽  
pp. 757-760 ◽  
Author(s):  
Richard Leblanc ◽  
Sabah Bekhor ◽  
Denis Melanson ◽  
Stirling Carpenter
Keyword(s):  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Obstructive Hydrocephalus ◽  
Choroid Plexus Papilloma ◽  
Blurred Vision ◽  
Content Type ◽  
Biological Potential ◽  
History Of ◽  
Fine Print ◽  
Plexus Papilloma

✓ Choroid plexus papillomas can metastasize to the subarachnoid space, but extensive metastasis has only been reported when the tumors are malignant. The authors report a case of diffuse, extensive metastasis to the craniospinal leptomeninges from a benign fourth ventricular choroid plexus papilloma in an adult. This 19-year-old woman presented with a 2-year history of headache, blurred vision, diplopia, and ataxia. Magnetic resonance imaging of the brain and spinal cord revealed obstructive hydrocephalus caused by a 4-cm, partially calcified, inhomogeneously enhancing tumor of the fourth ventricle that was displacing the pons, medulla oblongata, and cerebellum. Innumerable cystic lesions of varying size were also seen in the cranial and spinal leptomeninges. Histological examination of the resected fourth ventricular tumor and of a few of the leptomeningeal lesions revealed a benign choroid plexus papilloma and leptomeningeal choroid plexus cysts. This singular case of diffuse and extensive metastasis to the craniospinal leptomeninges from a histologically benign fourth ventricular papilloma adds to the available information about the biological potential of these tumors and expands the differential diagnosis of posterior fossa lesions with subarachnoid metastasis.

Radiation therapy of a choroid plexus papilloma of the cerebellopontine angle with bone involvement

1981 ◽  
Vol 54 (2) ◽  
pp. 245-247 ◽  
Author(s):  
Mahmoud G. Naguib ◽  
Shelley N. Chou ◽  
Angeline Mastri
Keyword(s):  
Radiation Therapy ◽  
Choroid Plexus ◽  
Cerebellopontine Angle ◽  
Choroid Plexus Papilloma ◽  
Bone Destruction ◽  
Bone Involvement ◽  
Content Type ◽  
Fine Print ◽  
Plexus Papilloma

✓ A case is reported of cerebellopontine angle choroid plexus papilloma with overlying bone destruction. Its favorable response to radiation therapy following subtotal excision is described.

Inflammatory pseudotumor of the choroid plexus

1993 ◽  
Vol 79 (6) ◽  
pp. 939-942 ◽  
Author(s):  
José Pimentel ◽  
Adília Costa ◽  
Luís Távora
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Choroid Plexus ◽  
Inflammatory Pseudotumor ◽  
Pathological Examination ◽  
Intraventricular Tumor ◽  
Content Type ◽  
Left Lateral Ventricle ◽  
The Central Nervous System ◽  
Fine Print

✓ The case of an 18-year-old man with a tumor of the left lateral ventricle is reported. The mass was observed to be contiguous with the choroid plexus but could be totally removed. Pathological examination disclosed an inflammatory pseudotumor. The authors review the literature on this lesion and related disorders involving the central nervous system and stress the need for a morphological differential diagnosis. Inflammatory pseudotumor should be considered in any case of intraventricular tumor.

Adult choroid plexus papilloma of the posterior fossa mimicking a hemangioblastoma

2000 ◽  
Vol 92 (5) ◽  
pp. 870-872 ◽  
Author(s):  
Roberto García-Valtuille ◽  
Faustino Abascal ◽  
Ana I. García-Valtuille ◽  
J. Ignacio Pinto ◽  
Luis Cerezal ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Choroid Plexus ◽  
Posterior Fossa ◽  
Choroid Plexus Papilloma ◽  
Mr Images ◽  
Content Type ◽  
Tomography Imaging ◽  
Fine Print ◽  
Plexus Papilloma

✓ The authors report a case of cystic choroid plexus papilloma that originated in the posterior fossa. No connection with the ventricular system was found intraoperatively. Magnetic resonance (MR) and computerized tomography imaging did not furnish a diagnosis, but findings of pathological examinations were consistent with those of choroid plexus papilloma. The authors describe the different appearances of the tumor on MR images and discuss the differential diagnosis with other tumors of the posterior fossa.

scholarly journals Choroid plexus papillomas are induced by c-Myc overexpression in the choroid plexus via a T-cell inflammatory mechanism

2019 ◽  
Vol 21 (Supplement_4) ◽  
pp. iv9-iv10
Author(s):  
Ashirwad Merve ◽  
Xinyu Zhang ◽  
Nicola Pomella ◽  
Serena Acquati ◽  
Joerg Hoeck ◽  
...  
Keyword(s):  
T Cell ◽  
Mouse Model ◽  
Choroid Plexus ◽  
Tumour Size ◽  
Choroid Plexus Papilloma ◽  
Experimental Models ◽  
Chemotherapeutic Agents ◽  
Human Choroid Plexus ◽  
Choroid Plexus Papillomas ◽  
Plexus Papilloma

Abstract Choroid plexus tumours (CPT) account for up to 20% of brain tumours in children under 2 years of age. Histologically CPTs are classified into three categories - Choroid Plexus Papilloma (CPP), Atypical Choroid Plexus Papilloma (ACPP) and Choroid Plexus Carcinoma (CPC). Recent literature demonstrates that CPP and ACPP are molecularly distinct from CPC. Initial management for CPT include surgery followed by adjuvant therapy in selected patients. Currently there are no disease-specific chemotherapeutic agents available, possibly because of their rarity and paucity of faithful pre-clinical experimental models. In this study we show that c-Myc overexpression in the choroid plexus epithelium induces T-cell inflammation-dependent choroid plexus papillomas in a mouse model. We demonstrate that c-MYC is expressed in a substantial proportion of human choroid plexus tumours and that this subgroup of tumours is characterised by an inflammatory transcriptome and significant inflammatory infiltrates. We observed that triple transgenic compound mutant mouse model with c-Myc overexpression in an immune-suppressed background led to a decreased incidence of CPP and reduced tumour bulk. A reduced tumour size was also observed when c-Myc overexpressing mice were treated with anti-CD3 antibodies. Our data raise the possibility that benign choroid plexus tumours expressing c-MYC could be amenable to medical therapy with anti-inflammatory drugs.

Cerebral sparganosis

1990 ◽  
Vol 73 (1) ◽  
pp. 147-150 ◽  
Author(s):  
Andrew Mitchell ◽  
Bernd W. Scheithauer ◽  
Patrick J. Kelly ◽  
Glenn S. Forbes ◽  
Jon E. Rosenblatt
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Surgical Removal ◽  
Asian Countries ◽  
Content Type ◽  
Chronic Abscess ◽  
The Central Nervous System ◽  
Cerebral Sparganosis ◽  
Tapeworm Infection ◽  
Fine Print

✓ The tapeworm Spirometra mansonoides infects man worldwide, particularly in Asian countries. Rarely, the central nervous system is involved; such a case is presented here. In the total of 12 reported cases, including the case described, the worm presented clinically as a mass suspicious for neoplasm or chronic abscess cavity. Surgical removal was invariably curative in each case. Although infrequent, the possibility of tapeworm infection should be entertained in the evaluation of intracranial masses in patients who have visited exotic locales.

Third ventricular choroid plexus papilloma with psychosis

1997 ◽  
Vol 87 (1) ◽  
pp. 103-105 ◽  
Author(s):  
Benjamin S. Carson ◽  
Jon D. Weingart ◽  
Michael Guarnieri ◽  
Paul G. Fisher
Keyword(s):  
Choroid Plexus ◽  
Behavioral Problems ◽  
Third Ventricle ◽  
Choroid Plexus Papilloma ◽  
Pathological Examination ◽  
Psychiatric Evaluation ◽  
Content Type ◽  
Resected Tumor ◽  
History Of ◽  
Plexus Papilloma

✓ This 9-year-old boy with a history of behavioral problems and worsening psychosis responded initially to treatment with haloperidol. However, a magnetic resonance image obtained as part of his psychiatric evaluation revealed an anterior third ventricle tumor and mild-to-moderate hydrocephalus. The resected tumor was found on pathological examination to be a choroid plexus papilloma. The patient had an uneventful postoperative course and remained free of psychosis or mood disorder at 1-year follow-up examination.

Central nervous system mesenchymal chondrosarcoma

1984 ◽  
Vol 61 (2) ◽  
pp. 375-381 ◽  
Author(s):  
Griffith R. Harsh ◽  
Charles B. Wilson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Vascular Tumor ◽  
Mesenchymal Chondrosarcoma ◽  
Content Type ◽  
Meningeal Tumor ◽  
The Central Nervous System ◽  
Initial Resection ◽  
Mesenchymal Chondrosarcomas ◽  
Fine Print

✓ Local recurrence developed 6 years after the initial resection of an intraspinal meningeal tumor that originally was thought to be an angioblastic meningioma. Histological review of the pathology led to a change of that diagnosis to one of mesenchymal chondrosarcoma. The recurrent vascular tumor was embolized, then totally excised. Because this tumor had malignant features, the patient received irradiation and chemotherapy. No evidence of regrowth has been observed during a period of more than 4 years. Mesenchymal chondrosarcomas of the central nervous system and their treatment are reviewed.

Epidermoid and dermoid cysts

1977 ◽  
Vol 47 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Beniamino Guidetti ◽  
Franco M. Gagliardi
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Postoperative Complications ◽  
Clinical Data ◽  
Late Results ◽  
Content Type ◽  
Operating Technique ◽  
The Central Nervous System ◽  
Fine Print

✓ The authors report on the clinical data, operating technique, postoperative complications, and late results in a series of 31 epidermoid and 21 dermoid cysts of the central nervous system.

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