scholarly journals Utilization of Pre-Anesthetic Medications for Major Surgical Procedures at a Tertiary Care Center: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (224) ◽  
Author(s):  
Rekha Shah ◽  
Roshan Pradhan ◽  
Arbindra Shah

Introduction: Drug utilization research is an important tool to analyze the use of drugs with specialemphasis on medical, social, and economic consequences in society. This study aims to find out theutilization of pre-anesthetic medications in a major surgical procedure. Methods: A descriptive cross-sectional study was conducted from 15th April - 15th August 2019 inthe postoperative ward at Birat Medical College and Teaching Hospital. The convenience samplingmethod was used after ethical clearance from the Institutional Review Committee (IRC) of BiratMedical College and Teaching Hospital, Biratnagar, Nepal. About 400 patients were studied.The collected data were entered into a statistical package for social science version 20 for furthercalculations at 95% Confidence Interval. Results: Out of 400 patients, 215 (53.8%) of patients were underwent into different major surgeries.All patients received midazolam 2 mg except children (1 mg) and Pethidine 25 mg along with 0.2 mgglycopyrrolate 352 (88%), ondansetron 276 (69%) and others 58 (14.5%) as a preanesthetic agent. Forgeneral anesthesia propofol, 30 mg have been utilized followed by fentanyl 306 (76.5%) and others(halothane, isoflurane, etc) 115 (28.8%). In case of prophylactic drug were ceftriaxone 500 mg, 100 mgmetoclopramide 387 (96.8%), dexamethasone 251 (62.8%), tramadol 237 (59.3%), 15 mg ketorolac 368(92%), ranitidine 163 (40.8%), and pantoprazole 237 (59.3%). Conclusions: The most commonly administered pre-anesthetic drugs were midazolam, pethidine,glycopyrrolate, and ondansetron. The incidence of postoperative nausea and vomiting the patientwithin 24 hours after surgery was significantly very low.  

Author(s):  
Sangeetha Raja ◽  
Jamuna Rani R ◽  
Kala P

ABSTRACTObjective: The aim of this study was to carry out adverse drug reactions (ADRs) monitoring in various departments of a tertiary care teaching hospital.Methods: A cross-sectional study was conducted on ADRs reported in the hospital from December 2012 to May 2013 after obtaining InstitutionalEthics Committee approval.Results: A total of 40 ADRs were reported, 47.50% were males and 52.50% were females. The female adult population was 45%. The majority of ADRswere due to antimicrobial agents especially beta-lactam antibiotics (42.5%) followed by NSAIDs (7.50%). A maximum number of patients (75%)were reported with dermatological manifestations. The department of medicine reported the highest number of ADRs (37.5%). As per Naranjo’sprobability scale, 62.5% reports were assessed as probable. 62.5% reports were documented as mild according to Modified Hartwig’s criteria forseverity assessment.Conclusion: This study was done to sensitize the practicing physicians on the importance of adverse drug monitoring and reporting.Keywords: Pharmacovigilance, Adverse drug reactions, Tertiary care teaching hospital, Antimicrobial agents.


2018 ◽  
Vol 21 (2) ◽  
pp. 169-176 ◽  
Author(s):  
Annemarie Bösch ◽  
Julia Wager ◽  
Boris Zernikow ◽  
Ralf Thalemann ◽  
Heidi Frenzel ◽  
...  

Author(s):  
Shivraj More ◽  
Sujatha P. ◽  
Karthiga Karthiga

Background: Menopause is an inevitable milestone in the reproductive life of every woman. The objective is to investigate menopausal knowledge, attitude, symptoms and management among the participants, to identify the differences according to their educational status and to examine correlations of knowledge, attitude and symptoms pertaining to menopause.Methods: This cross-sectional study was conducted for a period of 10 months in postmenopausal women attending a tertiary care center in Pondicherry, India with a structured questionnaire developed on the basis of the objective of the study.Results: 330 postmenopausal women were recruited, and all were aware of their postmenopausal status. Mean age at menopause was 45.91±2.66 years. 54.5% were aware about what menopause was while 5.5% were unaware. 12.1% had proper knowledge about cause of menopause, whereas 3.6% said it is due to god’s decision / turning point. Most prevalent symptoms were tiredness (89.6%) followed by vasomotor symptoms like hot flushes (88.5%) and night sweats (80.3%). Only 2.1% had used HRT for menopausal symptoms.Conclusions: Depth of knowledge is more important when concern is about greater health disrupter which tends to be imperceptible for a long time such as bone health and cardiovascular risk profile. Thus, the government could concentrate on providing health services to women in post reproductive age group also besides women in the reproductive age.


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