Vagal Influence on Reflexes of Somatic Musculature.

1938 ◽  
Vol 39 (1) ◽  
pp. 10-11
Author(s):  
W. Kaufman
Keyword(s):  
Somatic Musculature ◽  
Vagal Influence

scholarly journals The Alcohol Dehydrogenase Gene Is Nested in the outspread Locus of Drosophila melanogaster

Genetics ◽  
1996 ◽  
Vol 143 (2) ◽  
pp. 897-911 ◽  
Author(s):  
S McNabb ◽  
S Greig ◽  
T Davis
Keyword(s):  
Drosophila Melanogaster ◽  
Alcohol Dehydrogenase ◽  
Pcr Amplification ◽  
Transcription Unit ◽  
Adjacent Gene ◽  
Dehydrogenase Gene ◽  
Chromosomal Breakpoints ◽  
Splicing Patterns ◽  
Somatic Musculature

Abstract This report describes the structure and expression of the outspread (osp) gene of Drosophila melanogaster. Previous work showed that chromosomal breakpoints associated with mutations of the osp locus map to both sides of the alcohol dehydrogenase gene (Adh), suggesting that Adh and the adjacent gene Adh' are nested in osp. We extended a chromosomal walk and mapped additional osp mutations to define the maximum molecular limit of osp as 119 kb. We identified a 6-kb transcript that hybridizes to osp region DNA and is altered or absent in osp mutants. Accumulation of this RNA peaks during embryonic and pupal periods. The osp cDNAs comprise two distinct classes based on alternative splicing patterns. The 5′ end of the longest cDNA was extended by PCR amplification. When hybridized to the osp walk, the 5′ extension verifies that Adh and Adh' are nested in osp and shows that osp has a transcription unit of ≥74 kb. In situ hybridization shows that osp is expressed both maternally and zygotically. In the ovary, osp is transcribed in nurse cells and localized in the oocyte. In embryos, expression is most abundant in the developing visceral and somatic musculature.

P-1352 - Improvement of the link between cardiac vagal influence and delta sleep in sahs by long-term nCPAP treatment

2012 ◽  
Vol 27 ◽  
pp. 1
Author(s):  
F. Jurysta ◽  
C. Kempenaers ◽  
J.-P. Lanquart ◽  
P. Linkowski
Keyword(s):  
Delta Sleep ◽  
Vagal Influence

A new approach reveals syncytia within the visceral musculature ofDrosophila melanogaster

Development ◽  
2001 ◽  
Vol 128 (13) ◽  
pp. 2517-2524 ◽  
Author(s):  
Robert Klapper ◽  
Sandra Heuser ◽  
Thomas Strasser ◽  
Wilfried Janning
Keyword(s):  
Drosophila Melanogaster ◽  
Single Cell ◽  
Cell Transplantation ◽  
Reporter Gene ◽  
Mononuclear Cells ◽  
Single Cells ◽  
New Approach ◽  
Transplantation Technique ◽  
Somatic Musculature ◽  
Somatic Muscles

In order to reveal syncytia within the visceral musculature of Drosophila melanogaster, we have combined the GAL4/UAS system with the single-cell transplantation technique. After transplantation of single cells from UAS-GFP donor embryos into ubiquitously GAL4-expressing recipients, the expression of the reporter gene was exclusively activated in syncytia containing both donor- and recipient-derived nuclei. In the first trial, we tested the system in the larval somatic musculature, which is already known to consist of syncytia. By this means we could show that most of the larval somatic muscles are generated by clonally non-related cells. Moreover, using this approach we were able to detect syncytia within the visceral musculature – a tissue that has previously been described as consisting of mononuclear cells. Both the longitudinal visceral musculature of the midgut and the circular musculature of the hindgut consist of syncytia and persist through metamorphosis. This novel application of the transplantation technique might be a powerful tool to trace syncytia in any organism using the GAL4/UAS system.

A Preparation of Aplysia Fasciata For Intrasomatic Recording and Stimulation of Single Neurones During Locomotor Movements

1971 ◽  
Vol 54 (3) ◽  
pp. 659-676
Author(s):  
R. G. DE WEEVERS
Keyword(s):  
Ganglion Cells ◽  
Pedal Ganglion ◽  
Preliminary Results ◽  
Single Neurones ◽  
Sensory Responses ◽  
Motor Cells ◽  
Aplysia Fasciata ◽  
Pleural Ganglion ◽  
Somatic Musculature ◽  
Stimulation Of

1. Methods are described for suspending and clamping Aplysia fasciata so as to permit intrasomatic recording from neurones of the head ganglia during locomotor and other behavioural activities. 2. Sensory responses of neurones in the pedal ganglion are classified into four main types, all being distinct from those of pleural ganglion cells. 3. The pedal ganglion may well contain ‘motor cells’ for the greater part of the somatic musculature. 4. Preliminary results suggest that the pleural LGC may be involved in promoting a change from swimming to creeping behaviour.

The mutant not enough muscles (nem) reveals reduction of the Drosophila embryonic muscle pattern

1995 ◽  
Vol 108 (4) ◽  
pp. 1443-1454 ◽  
Author(s):  
S. Burchard ◽  
A. Paululat ◽  
U. Hinz ◽  
R. Renkawitz-Pohl
Keyword(s):  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Muscle Development ◽  
P Element ◽  
Dual Function ◽  
Methane Sulfonate ◽  
Visceral Mesoderm ◽  
Embryonic Muscle ◽  
Embryonic Muscle Development ◽  
Somatic Musculature

In a search for mutations affecting embryonic muscle development in Drosophila we identified a mutation caused by the insertion of a P-element, which we called not enough muscles (nem). The phenotype of the P-element mutation of the nem gene suggests that it may be required for the development of the somatic musculature and the chordotonal organs of the PNS, while it is not involved in the development of the visceral mesoderm and the dorsal vessel. Mutant embryos are characterized by partial absence of muscles, monitored by immunostainings with mesoderm-specific anti-beta 3 tubulin and anti-myosin heavy chain antibodies. Besides these muscle distortions, defects in the peripheral nervous system were found, indicating a dual function of the nem gene product. Ethyl methane sulfonate-induced alleles for the P-element mutation were created for a detailed analysis. One of these alleles is characterized by unfused myoblasts which express beta 3 tubulin and myosin heavy chain, indicating the state of cell differentiation.

scholarly journals Noninvasive muscle activity imaging using magnetography

2020 ◽  
Vol 117 (9) ◽  
pp. 4942-4947 ◽  
Author(s):  
Rodolfo R. Llinás ◽  
Mikhail Ustinin ◽  
Stanislav Rykunov ◽  
Kerry D. Walton ◽  
Guilherme M. Rabello ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Contrast Media ◽  
Electrical Activity ◽  
Real Time ◽  
Human Body ◽  
Muscle Activity ◽  
Muscular Activity ◽  
Exponential Increase ◽  
Somatic Musculature ◽  
The Magnetic Field

A spectroscopic paradigm has been developed that allows the magnetic field emissions generated by the electrical activity in the human body to be imaged in real time. The growing significance of imaging modalities in biology is evident by the almost exponential increase of their use in research, from the molecular to the ecological level. The method of analysis described here allows totally noninvasive imaging of muscular activity (heart, somatic musculature). Such imaging can be obtained without additional methodological steps such as the use of contrast media.

Regulatory peptides as modulators of vagal influence on cardiac rhythm

1995 ◽  
Vol 73 (9) ◽  
pp. 1235-1245 ◽  
Author(s):  
Vladimir M. Pokrowsky ◽  
Oleg E. Osadchiy
Keyword(s):  
Heart Rate ◽  
Vagus Nerve ◽  
Regulatory Peptides ◽  
Burst Stimulation ◽  
Different Types ◽  
Delta Sleep ◽  
Heart Contraction ◽  
The Right ◽  
Delta Sleep Inducing Peptide ◽  
Vagal Influence

When the right vagus nerve of anesthetized cats was stimulated with repetitive bursts of pulses, decelerated heart rate became synchronized to the rhythm of the vagal bursts. Each burst applied to the vagus was followed by a single heart contraction. Within defined limits an increase in the frequency of vagal bursts evoked a proportional acceleration of the heart, whereas a decreased frequency diminished the heart rate. Therefore, over the range of synchronization the heart rate was precisely controlled by changing the vagal stimulation rate. We concluded that the chronotropic effect evoked by vagal bursts was composed of two functionally different types of influence, namely, inhibitory tonic and synchronizing. The vagotropic influence of intravenously injected regulatory peptides was found to be selective for either the tonic or synchronizing component. For instance, dalargin (D-Ala2-Leu5-Arg6-enkephalin) and neokyotorphin selectively diminished the inhibitory tonic vagal influence, whereas delta sleep inducing peptide and neurotensin potentiated it. The magnitude of synchronizing vagal influence was not modified by these peptides. In contrast, secretin selectively inhibited the synchronizing vagal effect, but the tonic one was not affected. Somatostatin potentiated the synchronizing effect but diminished the tonic one. These data support the hypothesis that certain regulatory peptides can modulate the effects of repetitive vagal bursts on pacemaker activity.Key words: vagus nerve, burst stimulation, controlled bradycardia, regulatory peptides.

Heart rate at 4 s after the onset of exercise in endurance-trained men

2014 ◽  
Vol 92 (6) ◽  
pp. 476-480 ◽  
Author(s):  
Divanei Zaniqueli ◽  
Elis Aguiar Morra ◽  
Eduardo Miranda Dantas ◽  
Marcelo Perim Baldo ◽  
Luciana Carletti ◽  
...  
Keyword(s):  
Heart Rate ◽  
Frequency Spectrum ◽  
High Frequency ◽  
Sinus Node ◽  
Low Frequency ◽  
Spectral Indices ◽  
High Frequency Band ◽  
Band Ratio ◽  
Endurance Runners ◽  
Vagal Influence

It has been suggested that the increase in heart rate (HR) at the onset of exercise is caused by vagal withdrawal. In fact, endurance runners show a lower HR in maximum aerobic tests. However, it is still unknown whether endurance runners have a lower HR at 4 s after the onset of exercise (4th-sec-HR). We sought to measure the HR at the onset of the 4 s exercise test (4-sET), clarifying its relationship to heart rate variability (HRV), spectral indices, and cardiac vagal index (CVI) in endurance runners (ER) and healthy untrained controls (CON). HR at 4th-sec-HR, CVI, and percent HR increase during exercise were analyzed in the 4-sET. High frequency spectrum (HF-nu), low frequency spectrum (LF-nu), and low frequency/high frequency band ratio (LF/HF) were analyzed from the HRV. ER showed a significantly higher HF, and both a lower LF and LF/HF ratio compared with the CON. ER presented a significantly lower 4th-sec-HR, although neither CVI nor HR increases during exercise were statistically different from the CON. In conclusion, ER presented a lower 4th-sec-HR secondary to increased vagal influence over the sinus node. CVI seems to be too weak to use for discriminating individuals with respect to the magnitude of HR vagal control.

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