Synthesis of Cholestan -3-One Derivatives Possessing a C-2 Spiro-Oxindole Substituent
2018 ◽
Vol 42
(1)
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pp. 15-19
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Keyword(s):
X Ray
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A series of C-2 cholestan-3-one spiro-oxindole derivatives were prepared by the 1:3 dipolar cycloaddition reaction between the cholestan-3-one substituted by a C-2 arylidene and the azomethine ylid derived from isatin and sarcosine. The dipolarophiles were efficiently obtained by a Claisen-Schmidt reaction of cholestan-3-one and aromatic aldehydes. The structures of the products were established by a combination of NMR, high-resolution mass spectrometry (HRMS) and X-ray data analysis.
2019 ◽
Vol 43
(7-8)
◽
pp. 287-292
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2019 ◽
Vol 43
(1-2)
◽
pp. 63-66
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2014 ◽
Vol 29
(1)
◽
pp. 119-127
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2020 ◽
Vol 308
◽
pp. 110180
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