Role of contrast-enhanced ultrasound guidance in core-needle biopsy for diagnosis of cervical tuberculous lymphadenitis

Author(s):  
Dan Zhao ◽  
Ya-Qin Shao ◽  
Jun Hu ◽  
Dan Liu ◽  
Wei Tang ◽  
...  

OBJECTIVE: To investigate the diagnostic value of core-needle biopsy (CNB) guided by contrast-enhanced ultrasound (CEUS) in cervical tuberculous lymphadenitis (CTL). METHODS: 178 patients with pathological confirmation of CTL were retrospectively enrolled. All of them had undergone CNB prior to the final surgery. According to the different ways of puncture guidance, they were divided into two groups: conventional ultrasound (US) group (n = 81) and CEUS group (n = 97). The comparison of diagnostic efficacy between two groups was compared and analyzed. RESULTS: Among the 178 patients, 146 were directly diagnosed as CTL by CNB, including 59 patients in CEUS group and 87 patients in US group. The diagnostic accuracy were 89.7% (87/97) and 72.8% (59/81), respectively (P <  0.01). For subgroup analyses, differences among diagnostic efficacy ascribed to the different guiding methods were significant in medium size group (>2.0 cm and ≤3.0 cm) and large size group (>3.0 cm), 91.7% for CEUS group vs. 69.0% for US group (P <  0.05) and 84.4% for CEUS group vs. 57.7% for US group (P <  0.05), respectively. CONCLUSIONS: In the diagnosis of CTL, compared with the US-guided CNB, CEUS-guided CNB have certain advantages, especially for larger lymph nodes.

2018 ◽  
Vol 2018 ◽  
pp. 1-9
Author(s):  
Jian-hua Zhou ◽  
Hong-bo Shan ◽  
Wei Ou ◽  
Yun-xian Mo ◽  
Jin Xiang ◽  
...  

Based on the option that ultrasound-guided core needle biopsy (US-CNB) of the enhanced portion of anterior mediastinal masses (AMMs) identified by contrast-enhanced ultrasound (CEUS) would harvest viable tissue and benefit the histological diagnoses, a retrospective study was performed to elucidate the correlation between the prebiopsy CEUS and diagnostic yield of AMMs and found that CEUS potentially improved the diagnostic yield of AMMs compared with conventional US with a significant increase in the cellularity of samples. Furthermore, the marginal blood flow signals and absence of necrosis can predict the diagnostic yield of AMM. It was concluded that US-CNB of the viable part of AMMs, as verified by CEUS, was able to harvest sufficient tissue with more cellularity that could be used for ancillary studies and improve the diagnostic yield. And CEUS was recommended to those patients with AMMs undergoing repeated US-CNB, with the absence of marginal blood signals or presence of necrosis.


2010 ◽  
Vol 20 (11) ◽  
pp. 2740-2748 ◽  
Author(s):  
Armanda De Marchi ◽  
◽  
Elena Maria Brach del Prever ◽  
Alessandra Linari ◽  
Simona Pozza ◽  
...  

Ultrasound ◽  
2019 ◽  
Vol 28 (1) ◽  
pp. 58-61
Author(s):  
Benjamin Leenknegt ◽  
Stephen Moore ◽  
Cheng Fang ◽  
Nabil Kibriya ◽  
Stephen Gregory ◽  
...  

Introduction Splenic lesions are uncommon and frequently cause a diagnostic dilemma, often with non-specific findings on both ultrasound and cross-sectional imaging with histological confirmation necessary. To reduce patient morbidity, primarily from haemorrhage and to increase diagnostic yield, precise imaging and biopsy targeting are needed. Case We present a case of an indeterminate complex splenic lesion, with areas of necrosis which required histological diagnosis. Contrast-enhanced ultrasound-guided percutaneous core needle biopsy was undertaken to provide real-time imaging guidance, increasing viable lesion targeting and helping to avoid areas of necrosis. Conclusion Contrast-enhanced ultrasound guidance of the percutaneous core needle biopsy allowed increased operator confidence in lesional targeting accuracy and reduced the number of passes required for biopsy, simultaneously maximising histological yield and minimising patient morbidity.


2019 ◽  
Vol 57 (08) ◽  
pp. 945-951
Author(s):  
Corinna Trenker ◽  
Christoph F. Dietrich ◽  
Elena Ziegler ◽  
Albrecht Neesse ◽  
Christian Görg

Abstract Introduction Little is known about the imaging of omental pathologies. The aim of the current study was to determine the value of B-mode ultrasound (B-US), contrast-enhanced ultrasound (CEUS), and ultrasound-guided core needle biopsy for the differential diagnosis of benign and malignant omental pathologies. Patients and methods A retrospective evaluation (2008–2017) was performed in 44 patients (median 65,5 years, mean 64 years [47–83], 27 male, 17 female) with histological (40/44 [91 %]) or cytological (4/44 [9 %]) proven omental lesions. Clinical signs and final diagnosis, size, B-US and CEUS findings, and complications were analyzed. Results Omental thickening was in n = 36 (81.8 %) of the cases malignant (mOL) and in n = 8 (18.2 %) benign (bOL). Twenty-six (59.1 %) patients had ascites (n = 24 [66.7 %] mOL, n = 2 [25 %] bOL). The average tumor thickness was 23 mm (24 mm in mOL, 20 mm in bOL). Interventional complications were not observed. Discussion The majority of omental lesions are malignant. The differentiation between a malignant or benign cause of thickening is not possible by any imaging method. CEUS is helpful to determine vital tissue before biopsy. Ultrasound-guided core-needle biopsy allows final diagnosis of omental thickening if > 10 mm and should be performed prior to the more invasive and complicative diagnostic laparoscopy.


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