scholarly journals Using contrast-enhanced ultrasound to guide a successful biopsy of a splenic sarcomatoid carcinoma

Ultrasound ◽  
2019 ◽  
Vol 28 (1) ◽  
pp. 58-61
Author(s):  
Benjamin Leenknegt ◽  
Stephen Moore ◽  
Cheng Fang ◽  
Nabil Kibriya ◽  
Stephen Gregory ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Sarcomatoid Carcinoma ◽  
Contrast Enhanced Ultrasound ◽  
Diagnostic Dilemma ◽  
Core Needle ◽  
Patient Morbidity ◽  
Contrast Enhanced ◽  
Percutaneous Core Needle Biopsy

Introduction Splenic lesions are uncommon and frequently cause a diagnostic dilemma, often with non-specific findings on both ultrasound and cross-sectional imaging with histological confirmation necessary. To reduce patient morbidity, primarily from haemorrhage and to increase diagnostic yield, precise imaging and biopsy targeting are needed. Case We present a case of an indeterminate complex splenic lesion, with areas of necrosis which required histological diagnosis. Contrast-enhanced ultrasound-guided percutaneous core needle biopsy was undertaken to provide real-time imaging guidance, increasing viable lesion targeting and helping to avoid areas of necrosis. Conclusion Contrast-enhanced ultrasound guidance of the percutaneous core needle biopsy allowed increased operator confidence in lesional targeting accuracy and reduced the number of passes required for biopsy, simultaneously maximising histological yield and minimising patient morbidity.

scholarly journals Contrast-Enhanced Ultrasound Improves the Pathological Outcomes of US-Guided Core Needle Biopsy That Targets the Viable Area of Anterior Mediastinal Masses

2018 ◽  
Vol 2018 ◽  
pp. 1-9
Author(s):  
Jian-hua Zhou ◽  
Hong-bo Shan ◽  
Wei Ou ◽  
Yun-xian Mo ◽  
Jin Xiang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Contrast Enhanced Ultrasound ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Mediastinal Masses ◽  
Contrast Enhanced ◽  
Ancillary Studies

Based on the option that ultrasound-guided core needle biopsy (US-CNB) of the enhanced portion of anterior mediastinal masses (AMMs) identified by contrast-enhanced ultrasound (CEUS) would harvest viable tissue and benefit the histological diagnoses, a retrospective study was performed to elucidate the correlation between the prebiopsy CEUS and diagnostic yield of AMMs and found that CEUS potentially improved the diagnostic yield of AMMs compared with conventional US with a significant increase in the cellularity of samples. Furthermore, the marginal blood flow signals and absence of necrosis can predict the diagnostic yield of AMM. It was concluded that US-CNB of the viable part of AMMs, as verified by CEUS, was able to harvest sufficient tissue with more cellularity that could be used for ancillary studies and improve the diagnostic yield. And CEUS was recommended to those patients with AMMs undergoing repeated US-CNB, with the absence of marginal blood signals or presence of necrosis.

Accuracy of core-needle biopsy after contrast-enhanced ultrasound in soft-tissue tumours

2010 ◽  
Vol 20 (11) ◽  
pp. 2740-2748 ◽  
Author(s):  
Armanda De Marchi ◽  
◽  
Elena Maria Brach del Prever ◽  
Alessandra Linari ◽  
Simona Pozza ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Contrast Enhanced Ultrasound ◽  
Soft Tissue Tumours ◽  
Core Needle ◽  
Contrast Enhanced

scholarly journals Diagnostic yield of percutaneous core needle biopsy in suspected soft tissue lesions of extremities

2019 ◽  
Vol 47 (6) ◽  
pp. 2598-2606 ◽  
Author(s):  
Dianwen Qi ◽  
Ming Zhao ◽  
Tongyu Hu ◽  
Guochuan Zhang
Keyword(s):  
Soft Tissue ◽  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Benign Lesions ◽  
Core Needle ◽  
Soft Tissue Lesions ◽  
Percutaneous Core Needle Biopsy ◽  
Sensitivity Specificity

Objective This retrospective study was performed to investigate the diagnostic yield of percutaneous core needle biopsy (CNB) for suspected soft tissue lesions of the extremities. Methods The medical records of 139 consecutive patients who underwent percutaneous CNB for suspected soft tissue lesions of the extremities from January 2014 to December 2016 at a single institution were reviewed. The pathologic findings or clinical follow-ups were used to evaluate the performance of CNB. Alterations in the treatment regimen from pre- to post-biopsy were also analyzed. Complications, when present, were documented. Results In total, 141 biopsy procedures were performed in 139 patients. In total, 136 (96%) biopsies were successful, among which 5 were false-negative and 131 were diagnosed accurately. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CNB in the differentiation of malignant from benign lesions were 94%, 100%, 96%, 100%, and 90%, respectively. The treatment regimen was altered based on the biopsy findings in 25 cases. Two patients developed mild nerve injury but fully recovered during follow-up. Conclusions CNB is effective and safe, with high sensitivity, specificity, and accuracy for the diagnosis of soft tissue lesions, especially for differentiating malignant from benign lesions.

Role of contrast-enhanced ultrasound guidance in core-needle biopsy for diagnosis of cervical tuberculous lymphadenitis

2020 ◽  
pp. 1-9
Author(s):  
Dan Zhao ◽  
Ya-Qin Shao ◽  
Jun Hu ◽  
Dan Liu ◽  
Wei Tang ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Value ◽  
Size Group ◽  
Medium Size ◽  
Tuberculous Lymphadenitis ◽  
Contrast Enhanced Ultrasound ◽  
Diagnostic Efficacy ◽  
Core Needle ◽  
Contrast Enhanced

OBJECTIVE: To investigate the diagnostic value of core-needle biopsy (CNB) guided by contrast-enhanced ultrasound (CEUS) in cervical tuberculous lymphadenitis (CTL). METHODS: 178 patients with pathological confirmation of CTL were retrospectively enrolled. All of them had undergone CNB prior to the final surgery. According to the different ways of puncture guidance, they were divided into two groups: conventional ultrasound (US) group (n = 81) and CEUS group (n = 97). The comparison of diagnostic efficacy between two groups was compared and analyzed. RESULTS: Among the 178 patients, 146 were directly diagnosed as CTL by CNB, including 59 patients in CEUS group and 87 patients in US group. The diagnostic accuracy were 89.7% (87/97) and 72.8% (59/81), respectively (P <  0.01). For subgroup analyses, differences among diagnostic efficacy ascribed to the different guiding methods were significant in medium size group (>2.0 cm and ≤3.0 cm) and large size group (>3.0 cm), 91.7% for CEUS group vs. 69.0% for US group (P <  0.05) and 84.4% for CEUS group vs. 57.7% for US group (P <  0.05), respectively. CONCLUSIONS: In the diagnosis of CTL, compared with the US-guided CNB, CEUS-guided CNB have certain advantages, especially for larger lymph nodes.

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