Advancements in data analysis and visualisation techniques to support multiple single-subject analyses: an assessment of movement coordination and coordination variability

Author(s):  
R Needham ◽  
R Naemi ◽  
N Chockalingam

Vector coding is a data analysis technique that quantifies inter-segmental coordination and coordination variability of human movement. The usual reporting of vector coding time-series data can be difficult to interpret when multiple trials are superimposed on the same figure. This study describes and presents novel data visualisations for displaying data from vector coding that supports multiple single- subject analyses. The dataset used in this study describes the lumbar-pelvis coordination in the transverse plane during a gait cycle. The data visualisation techniques presented in this study consists of the use of colour and data bars to map and profile coordination pattern and coordination variability data. The use of colour mapping provides the option to classify commonalities and differences in patterns of coordination between segment couplings and between individuals across a big dataset. Data bars display segmental dominancy data that can provide an intuitive summary on coupling angle distribution over time. The data visualisation in this study may provide further insight on how people with adolescent idiopathic scoliosis perform goal-orientated movements following an intervention, which would support clinical management strategies.

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Takuya Ibara ◽  
Masaya Anan ◽  
Ryosuke Karashima ◽  
Kiyotaka Hada ◽  
Koichi Shinkoda ◽  
...  

There are limited reports on segment movement and their coordination pattern during gait in patients with hip osteoarthritis. To avoid the excessive stress toward the hip and relevant joints, it is important to investigate the coordination pattern between these segment movements, focusing on the time series data. This study aimed to quantify the coordination pattern of lumbar, pelvic, and thigh movements during gait in patients with hip osteoarthritis and in a control group. An inertial measurement unit was used to measure the lumbar, pelvic, and thigh angular velocities during gait of 11 patients with hip osteoarthritis and 11 controls. The vector coding technique was applied, and the coupling angle and the appearance rate of coordination pattern in each direction were calculated and compared with the control group. Compared with the control group, with respect to the lumbar/pelvic segment movements, the patients with hip osteoarthritis spent more rates in anti-phase and lower rates in in-phase lateral tilt movement. With respect to the pelvic/thigh segment movements, the patients with hip osteoarthritis spent more rates within the proximal- and in-phases for lateral tilt movement. Furthermore, patients with osteoarthritis spent lower rates in the distal-phase for anterior/posterior tilt and rotational movement. Patients with hip osteoarthritis could not move their pelvic and thigh segments separately, which indicates the stiffness of the hip joint. The rotational movement and lateral tilt movements, especially, were limited, which is known as Duchenne limp. To maintain the gait ability, it seems important to pay attention to these directional movements.


2013 ◽  
Author(s):  
Stephen J. Tueller ◽  
Richard A. Van Dorn ◽  
Georgiy Bobashev ◽  
Barry Eggleston

2021 ◽  
Vol 83 (3) ◽  
Author(s):  
Maria-Veronica Ciocanel ◽  
Riley Juenemann ◽  
Adriana T. Dawes ◽  
Scott A. McKinley

AbstractIn developmental biology as well as in other biological systems, emerging structure and organization can be captured using time-series data of protein locations. In analyzing this time-dependent data, it is a common challenge not only to determine whether topological features emerge, but also to identify the timing of their formation. For instance, in most cells, actin filaments interact with myosin motor proteins and organize into polymer networks and higher-order structures. Ring channels are examples of such structures that maintain constant diameters over time and play key roles in processes such as cell division, development, and wound healing. Given the limitations in studying interactions of actin with myosin in vivo, we generate time-series data of protein polymer interactions in cells using complex agent-based models. Since the data has a filamentous structure, we propose sampling along the actin filaments and analyzing the topological structure of the resulting point cloud at each time. Building on existing tools from persistent homology, we develop a topological data analysis (TDA) method that assesses effective ring generation in this dynamic data. This method connects topological features through time in a path that corresponds to emergence of organization in the data. In this work, we also propose methods for assessing whether the topological features of interest are significant and thus whether they contribute to the formation of an emerging hole (ring channel) in the simulated protein interactions. In particular, we use the MEDYAN simulation platform to show that this technique can distinguish between the actin cytoskeleton organization resulting from distinct motor protein binding parameters.


2020 ◽  
Author(s):  
Raul Bardaji ◽  
Jaume Piera ◽  
Juanjo Dañobeitia ◽  
Ivan Rodero

<p>In marine sciences, the way in which many research groups work is changing as scientists use published data to complement their field campaign data online, thanks to the large increase in the number of open access observations. Many institutions are making great efforts to provide the data following FAIR principles (findability, accessibility, interoperability, and reusability) and are bringing together interdisciplinary teams of data scientists and data engineers.</p><p>There are different platforms for downloading marine and oceanographic data and many libraries to analyze data. However, the reality is that scientists continue to have difficulty finding the data they need. On many occasions, data platforms provide information about the metadata, but they do not show any underlying graph of the data that can be downloaded. Sometimes, scientists cannot download only the data parameters of interest and have to download huge amounts of data with other not useful parameters for their studies. On other occasions, the platform allows to download the data parameters of interest but offers the time-series data as many files, and it is the scientist who has to join the pieces of data into a single dataset to be analyzed correctly. EMSO ERIC is developing a data service that helps reduce the burden of scientists to search and acquire data as much as possible.</p><p> </p><p>We present the EMSO ERIC DataLab web application, which provides users with capabilities to preview harmonized data from the EMSO ERIC observatories, perform some basic data analyses, create or modify datasets, and download them. Use case scenarios of the DataLab include the creation of a NetCDF file with time-series information across EMSO ERIC observatories.</p><p>The DataLab has been developed using engineering best practices and trend technologies for big data management, including specialized Python libraries for web environments and oceanographic data analysis, such as Plotly, Dash, Flask, and the Module for Ocean Observatory Data Analysis (MOODA).</p>


2021 ◽  
Author(s):  
Tetsuya Yamada ◽  
Shoi Shi

Comprehensive and evidence-based countermeasures against emerging infectious diseases have become increasingly important in recent years. COVID-19 and many other infectious diseases are spread by human movement and contact, but complex transportation networks in 21 century make it difficult to predict disease spread in rapidly changing situations. It is especially challenging to estimate the network of infection transmission in the countries that the traffic and human movement data infrastructure is not yet developed. In this study, we devised a method to estimate the network of transmission of COVID-19 from the time series data of its infection and applied it to determine its spread across areas in Japan. We incorporated the effects of soft lockdowns, such as the declaration of a state of emergency, and changes in the infection network due to government-sponsored travel promotion, and predicted the spread of infection using the Tokyo Olympics as a model. The models used in this study are available online, and our data-driven infection network models are scalable, whether it be at the level of a city, town, country, or continent, and applicable anywhere in the world, as long as the time-series data of infections per region is available. These estimations of effective distance and the depiction of infectious disease networks based on actual infection data are expected to be useful in devising data-driven countermeasures against emerging infectious diseases worldwide.


2009 ◽  
Vol 10 (1) ◽  
pp. 65-88
Author(s):  
Nandita Dasgupta

The objective of this paper is to examine the effects of international trade and investment related macro economic variables, namely, exports, imports and FDI inflows on the outflows of FDI from India over 1970 through 2005. Using time series data analysis, the empirical part of the paper finds unidirectional Granger Causality from export and import to FDI outflows but no such causality exists from FDI inflows to the corresponding outflows from India. Results confirm the assumption that lagged imports and exports are a driving force of ing front.


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