scholarly journals Pathologic Process

2020 ◽  
Author(s):  
Keyword(s):  
PEDIATRICS ◽  
1952 ◽  
Vol 9 (2) ◽  
pp. 204-211
Author(s):  
HERMAN YANNET ◽  
FRANK HORTON

The relative importance of the hypotonic type of cerebral palsy among the mentally defective is stressed. This type of cerebral palsy manifests itself in either of three clinical pictures with some overlapping, namely, atonic, ataxic and athetoid. The etiology is variable in each of these groups and may be effective in either the prenatal, paranatal or postnatal periods. The severity of the mental defect, the high incidence of convulsive disorders, and the tendency toward microcephaly point towards the widespread nature of the pathologic process regardless of etiology. The syndrome of atonic diplegia, as herein described, is probably invariably associated with the more severe degrees of mental deficiency.


1998 ◽  
Vol 79 (4) ◽  
pp. 280-281
Author(s):  
R. I. Zhivoglyad

The results of the influence of the Hirudo medicinalis leeches and antibacterial therapy on homeostasis indices in patients with hormono dependent and inflammatory diseases of genital organs are analyzed. The positive effect of hirudotherapy courses on general and biochemical indices of blood changed as a result of the pathologic process progression is shown. The combined use of hirudotherapy and antibacterial treatment is recommended.


PEDIATRICS ◽  
1956 ◽  
Vol 18 (2) ◽  
pp. 318-322
Author(s):  
Robert B. Greenblatt ◽  
James W. Bennett

MANY mothers bring their young daughters to the pediatrician because they have noticed a discharge on the child's underclothing. Most of such discharges are nothing more than desquamation of the epithelial cells at perhaps a more rapid pace than usual. Such a discharge, commonly referred to as "whites," occurs normally in the adult female. No pathologic process is involved in either the child or the woman and no treatment is indicated. On the other hand, a discharge which is irritating, malodorous, and provokes an inflammatory response, has a pathologic background. By far the greater number of such cases fall into one of the following categories: (a) Nonspecific vaginitis which may be due to the presence of organisms which find their way into the vaginal canal either through insertion of the child's finger or some foreign object, or may appear for no apparent predisposing reasons. Among the organisms found are pneumococcus, streptococcus, staphylococcus, diphtheroids, colon bacillus, etc. The treatment consists primarily of removing or correcting the underlying factor and cleansing measures. Frequently, attention to the technique of cleansing the rectal area following a bowel movement, daily bathing and a pitcher douche with saline twice a day will clear up the discharge. Sulfonamides by mouth, locally, or both may be effective in some cases. In other cases, the local use of a specific antibiotic such as Terramycin® or Aureomycin® has been effective (a 50 mg. capsule may be inserted into the vaginal canal daily for 5 to 7 days). (b) Another group of cases is due to the presence of foreign bodies in the vaginal canal. Any number and type of foreign bodies have been found in the vaginal canals of small children, such as safety pins, pencils, sticks, etc. The presence of a foreign body sets up an irritant reaction and causes a discharge, in most instances with a bloody component. The diagnosis may be made by inspection or by gentle rectal examination, pressing the vaginal wall through the rectum.


1995 ◽  
Vol 76 (1) ◽  
pp. 52-54
Author(s):  
D. M. Puchinyan ◽  
M. S. Sissakian

The microcirculation state in 48 patients with unilateral and bilateral deforming coxarthrosis of IIII stages and in 34 healthy persons aged 26 to 63 is studied using biomicroscopy method of bulbar conjunctiva vessels. It is established that the pronounced microcirculating disorders depend on the disease gravity and pathologic process occurrence. The most constant signs of microhemo- circulation disorder are intravescular and vascular changes.


2018 ◽  
Vol 24 (4) ◽  
pp. 455-462 ◽  
Author(s):  
Thomas W Link ◽  
Benjamin I Rapoport ◽  
Stephanie M Paine ◽  
Hooman Kamel ◽  
Jared Knopman

Background and purpose Embolization of the middle meningeal artery (MMA) has recently been proposed as an alternative to surgery for treatment of chronic subdural hematoma (SDH), and several case reports have been published supporting its efficacy. It has been suggested that the primary pathologic process in chronic SDH is repeated microhemorrhaging into the subdural collection from fragile neovasculature within the SDH membrane that arises from distal branches of the MMA. Embolization could thus provide a means of eliminating this chronic rebleeding. Materials and methods Images were selected from MMA embolization procedures performed at our institution in order to illustrate the technique and theory behind its efficacy for treatment of chronic SDH. Results Images from MMA angiograms demonstrate the variability of MMA anatomy and help illustrate the importance of avoiding potential ophthalmic collaterals and branches supplying cranial nerves. The findings of irregular wispiness of the distal MMA vasculature, contrast outlining of the SDH membrane on angiography, and homogenous increased density within the SDH on postembolization head computed tomography are described. Conclusion MMA embolization may provide a safe alternative for treatment of chronic SDH, but careful angiographic assessment of MMA anatomy should be performed to avoid potential complications. The findings illustrated here lend support to the theory that the pathologic process of chronic SDH is repeated leakage of blood products from an inflamed, abnormal arterial neovasculature within the SDH membrane that arises from the MMA, and thus selective embolization could provide an effective treatment.


Glia ◽  
2019 ◽  
Vol 67 (12) ◽  
pp. 2343-2359 ◽  
Author(s):  
Jin Wang ◽  
Xin Ding ◽  
Xiangyu Wu ◽  
Jing Liu ◽  
Rui Zhou ◽  
...  

2009 ◽  
Vol 37 (9) ◽  
pp. 1855-1867 ◽  
Author(s):  
Jonathan D. Rees ◽  
Nicola Maffulli ◽  
Jill Cook

Overuse disorders of tendons, or tendinopathies, present a challenge to sports physicians, surgeons, and other health care professionals dealing with athletes. The Achilles, patellar, and supraspinatus tendons are particularly vulnerable to injury and often difficult to manage successfully. Inflammation was believed central to the pathologic process, but histopathologic evidence has confirmed the failed healing response nature of these conditions. Excessive or inappropriate loading of the musculotendinous unit is believed to be central to the disease process, although the exact mechanism by which this occurs remains uncertain. Additionally, the location of the lesion (for example, the midtendon or osteotendinous junction) has become increasingly recognized as influencing both the pathologic process and subsequent management. The mechanical, vascular, neural, and other theories that seek to explain the pathologic process are explored in this article. Recent developments in the nonoperative management of chronic tendon disorders are reviewed, as is the rationale for surgical intervention. Recent surgical advances, including minimally invasive tendon surgery, are reviewed. Potential future management strategies, such as stem cell therapy, growth factor treatment, and gene transfer, are also discussed.


Sign in / Sign up

Export Citation Format

Share Document