Biological Challenge Agent

2020 ◽  
Author(s):  
Keyword(s):  
2017 ◽  
Vol 1 (1) ◽  
pp. 33
Author(s):  
Ratih Larasati ◽  
Lia M. Boediman ◽  
Mita Aswanti

Developmental, Individual Differences, Relationship-Based approach (DIR/Floortime) is one of the available interventions focused on increasing the quality of caregiver-child interaction. This study is aimed at investigating the effectiveness of DIR/Floortime to increase the ability to sustain attention on a 4 year-old child with Early Onset Attention-Deficit/Hyperactivity Disorder (ADHD). This is a qualitative research involving two participants, a boy diagnosed with ADHD, and the mother of the boy. This research utilized observation and interview in gathering the data, accompanying the use of observation log for duration of attention and frequency of distractedness specifically designed for this research, Functional Emotional Assessment Scale (FEAS), questionnaire and interview guideline: Observing Child’s Biological Challenge (OCBC), and Sensory Processing – Motor Planning Questionnaire (SPMPQ). The result of this study indicated that the application of DIR/Floortime principles is effective in increasing the ability to sustain attention on a 4 year-old child with Early Onset ADHD, along with the increase of the functional emotional development of both mother and child as shown with the increase of attention span, the decrease of frequency of distractibility, and score increase in the Functional Emotional Assessment Scale (FEAS).


2003 ◽  
Vol 10 (8) ◽  
pp. 887-890 ◽  
Author(s):  
Michael J Welch ◽  
Howard Halpern ◽  
Karen A Kurdziel
Keyword(s):  

2008 ◽  
Vol 33 (11) ◽  
pp. 1463-1469 ◽  
Author(s):  
Kenneth Abrams ◽  
Koen Schruers ◽  
Fiammetta Cosci ◽  
Shaun Sawtell

2019 ◽  
Vol 32 (6) ◽  
pp. e100140
Author(s):  
Donald J Robinaugh ◽  
Meredith J Ward ◽  
Emma R Toner ◽  
Mackenzie L Brown ◽  
Olivia M Losiewicz ◽  
...  

BackgroundCognitive–behavioural theories of panic disorder posit that panic attacks arise from a positive feedback loop between arousal-related bodily sensations and perceived threat. In a recently developed computational model formalising these theories of panic attacks, it was observed that the response to a simulated perturbation to arousal provided a strong indicator of vulnerability to panic attacks and panic disorder. In this review, we evaluate whether this observation is borne out in the empirical literature that has examined responses to biological challenge (eg, CO2 inhalation) and their relation to subsequent panic attacks and panic disorder.MethodWe searched PubMed, Web of Science and PsycINFO using keywords denoting provocation agents (eg, sodium lactate) and procedures (eg, infusion) combined with keywords relevant to panic disorder (eg, panic). Articles were eligible if they used response to a biological challenge paradigm to prospectively predict panic attacks or panic disorder.ResultsWe identified four eligible studies. Pooled effect sizes suggest that there is biological challenge response has a moderate prospective association with subsequent panic attacks, but no prospective relationship with panic disorder.ConclusionsThese findings provide support for the prediction derived from cognitive–behavioural theories and some preliminary evidence that response to a biological challenge may have clinical utility as a marker of vulnerability to panic attacks pending further research and development.Trial registration number135908.


2013 ◽  
Vol 25 (5) ◽  
pp. 719 ◽  
Author(s):  
Gábor Vajta

According to the analysis of papers published in major international journals, rapidly increasing application of vitrification is one of the greatest achievements in domestic animal and especially human embryology during the first decade of our century. This review highlights factors supporting or hampering this progress, summarises results achieved with vitrification and outlines future tasks to fully exploit the benefits of this amazing approach that has changed or will change many aspects of laboratory (and also clinical) embryology. Supporting factors include the simplicity, cost efficiency and convincing success of vitrification compared with other approaches in all species and developmental stages in mammalian embryology, while causes that slow down the progress are mostly of human origin: inadequate tools and solutions, superficial teaching, improper application and unjustified concerns resulting in legal restrictions. Elimination of these hindrances seems to be a slower process and more demanding task than meeting the biological challenge. A key element of future progress will be to pass the pioneer age, establish a consensus regarding biosafety requirements, outline the indispensable features of a standard approach and design fully-automated vitrification machines executing all phases of the procedure, including equilibration, cooling, warming and dilution steps.


2004 ◽  
Vol 23 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Cinzia Verde ◽  
Ennio Cocca ◽  
Donatella Pascale ◽  
Elio Parisi ◽  
Guido Frisco

2016 ◽  
Vol 4 (2) ◽  
pp. 63-69 ◽  
Author(s):  
Jonathan C.W. Edwards ◽  
Simon McGrath ◽  
Adrian Baldwin ◽  
Mark Livingstone ◽  
Andrew Kewley

2016 ◽  
Vol 30 (7) ◽  
pp. 641-653 ◽  
Author(s):  
Samantha G Farris ◽  
Michael J Zvolensky

Introduction: Although anxiety sensitivity has been reliably associated with smoking-anxiety comorbidity, there has not been a test of whether this construct moderates the effect of acute anxious arousal on actual smoking behavior. The present study utilized an experimental design to test the moderating role of anxiety sensitivity on laboratory-induced anxious arousal in terms of smoking urges and topography (puff style). Method: Participants were adult daily smokers ( n=90; Mage=43.6 SD =9.7); average 15.8 cigarettes per day). A between-subjects design was used; participants were randomly assigned to complete a biological challenge procedure consisting of either a single vital capacity inhalation of 35% carbon dioxide (CO2)-enriched air mixture or compressed room air. Smoking urges and smoking topography (puff behavior) were assessed before and after the challenge. Results: Results revealed a significant interaction between anxiety sensitivity and experimental condition ( b=−9.96, p=0.014), such that high anxiety sensitive smokers exposed to 35% CO2-enriched air reported significantly lower levels of smoking urges, relative to low anxiety sensitive smokers; the conditional effect of anxiety sensitivity was not observed for the room air condition. There were no significant interaction effects of experimental manipulation by anxiety sensitivity for any of the smoking topography outcomes. Discussion: The present results suggest for smokers with higher levels of anxiety sensitivity, the acute experience of anxious arousal is related to decreased subjective smoking urges. These data invite future research to explore the reasons for dampened smoking urges, including cardiorespiratory symptom severity.


2001 ◽  
Vol 2 (2) ◽  
pp. 118-126 ◽  
Author(s):  
Adriano Aguzzi ◽  
Fabio Montrasio ◽  
Pascal S. Kaeser
Keyword(s):  

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