scholarly journals Comparing the Quality of Life in Patients With Multiple Sclerosis Consuming Fingolimod and Cinnovex

2019 ◽  
Vol 5 (4) ◽  
pp. 151-160
Author(s):  
Alia Saberi ◽  
◽  
Hamidreza Hatamian ◽  
Amirreza Ghayeghran ◽  
Fatemeh Mola Hosseini ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Cross Sectional Study ◽  
Analysis Of Covariance ◽  
Life Questionnaire ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference ◽  
Chi Square Test

Background: Multiple Sclerosis (MS) is a chronic demyelinating, inflammatory, and degenerative disease of the central nervous system. MS gradually limits and deteriorates the patients’ quality of life. Objectives: This study aimed to evaluate and compare the quality of life in patients with MS consuming Fingolimod and Cinnovex. Materials & Methods: In an analytical cross-sectional study, 106 patients with Relapsing-Remitting MS (RRMS) referred to specialized neurology clinics of Guilan University of Medical Sciences were selected for the study using a convenience sampling method (52 patients consuming Fingolimod and 54 patients consuming Cinnovex). Then, we collected their demographic information and medical profile. The patients were assessed by the Hamburg quality of life questionnaire in MS. The obtained data were analyzed in SPSS V. 22 using the Chi-square test, independent t-test, Mann-Whitney U, one-way and multivariate analysis of covariance. Results: There was a significant difference between the two groups in terms of age, number of attacks in the last 6 months, and educational level (P<0.05). After controlling confounding variables, it was found that consumers of Fingolimod had a better quality of life. At the subscales level, this difference was significant only in the mood dimension (F=6.931, P=0.011, η=0.12). Conclusion: Patients consuming Fingolimod reported a better quality of life compared to consumers of Cinnovex. This improvement was mainly found in mood scores.

scholarly journals Does Locomotive Syndrome, Associated with Sarcopenia or otherwise, Influence Quality of Life in Individuals Aged over 80 years? Third Wave of the LOCOMOV Project

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Patrícia De Castro Rodrigues ◽  
Julia Carvalho Galiano ◽  
Virginia Fernandes Moça Trevizani ◽  
Fania Cristina Santos
Keyword(s):  
Quality Of Life ◽  
Oldest Old ◽  
Epidemiological Survey ◽  
Cross Sectional Study ◽  
P Value ◽  
Locomotive Syndrome ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

Introduction: Locomotion is a determinant of intrinsic capacity ofolder people and can be limited by dysfunction in locomotory organs,characterizing Locomotive Syndrome (LoS). Knowledge on locomotiveproblems and sarcopenia, and their interface with quality of life, in theoldest old in the literature is scarce.Objective: To evaluate the correlation between LoS and sarcopenia andtheir influence on quality of life in oldest old.Methods: A cross-sectional study of an observational, descriptive andanalytical epidemiological survey in independent older adults aged 80and over from São Paulo, Brazil and who participated in the third waveof the LOCOMOV Project, was carried out. Sociodemographic data,comorbidities, functioning in activities of daily living, physical functioning,quality of life, and presence of sarcopenia and LoS were assessed. Thestatistical analyses included the Test-for-Comparing-Two-Proportions,Pearson's Correlation Coefficient, the chi-Square test and Student´s t-test.Results: Thirty oldest old with a mean age of 89.1 years were evaluated.The prevalence of LoS was high (53.3%) and correlated significantly withchronic pain (p-value 0.024), worse performance on the SPPB and Gaitspeed (p-value <0.001). Sarcopenia was not correlated with LoS, but worsequality of life on the physical domain was significantly associated with LoS(p-value <0.001) regardless of the presence of sarcopenia.Conclusions: LoS was highly prevalent among the oldest old studied andnegatively impacted their quality of life, regardless of the presence ofsarcopenia. 

scholarly journals Determinants of quality of life among COVID-19 patients in Southwestern region of Bangladesh

2021 ◽  
Vol 0 ◽  
pp. 1-8
Author(s):  
Md. Injamul Haq Methun ◽  
M. Sheikh Giash Uddin ◽  
Iqramul Haq ◽  
Md. Asaduzzaman Noor ◽  
Md. Jakaria Habib ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Logistic Regression ◽  
Cross Sectional Study ◽  
Health Condition ◽  
Chi Square ◽  
Cross Sectional ◽  
Health Crisis ◽  
Value Set ◽  
Chi Square Test

Objectives: The outbreak of COVID-19 has caused an unprecedented health crisis and dramatically changed human lives. This study aims to identify risk factors related to health-related quality of life (HRQoL) among COVID-19 patients who were discharged from the hospital. Material and Methods: A total of 557 COVID-19 patients of Jhenaidah district of Bangladesh who had tested positive before February 1 of 2021 were selected for this cross-sectional study. The EuroQol 5-dimensional-5 level questionnaire was used to measure the HRQoL. Thai value set was used to assess the full health status. Chi-square test was used to find out the association of HRQoL with sociodemographic and clinical factors. Finally, logistic regression was used to find out the predictors of the dimensions of HRQoL. Results: Using the Thai value set, it is observed that 57.27% of participants had reported that they had experienced moderate or severe health problems. About 40.57% of the respondent reported anxiety or depression, whereas 39.14% of the participants had experienced moderate or severe pain or discomfort. The result of the logistic regression showed that age, gender, occupation, place of care, heart problems, and diabetes significantly affect various dimensions of the HRQoL. Conclusion: The COVID-19 significantly depletes the health condition of the patients in both mental and physical aspects. Therefore, the policy-makers and government should need to come with comprehensive strategies to reduce the psychological and physical health woe of COVID-19 patients.

scholarly journals Horizontal (vs. Vertical) Closure of the Neo-pharynx is Associated with Superior Postoperative Swallowing after Total Laryngectomy

2018 ◽  
Vol 97 (4-5) ◽  
pp. E31-E35 ◽  
Author(s):  
Giannis Thrasyvoulou ◽  
Petros V. Vlastarakos ◽  
Michael Thrasyvoulou ◽  
Aristides Sismanis
Keyword(s):  
Quality Of Life ◽  
Treatment Modality ◽  
Total Laryngectomy ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Swallowing Function ◽  
Cross Sectional ◽  
Surgical Closure ◽  
Significant Difference

We conducted a cross-sectional study to compare the horizontal and vertical methods used in the surgical closure of the neo-pharynx after total laryngectomy in terms of their effect on swallowing function, swallowing-related quality of life ( QOL), and overall QOL. We also assessed the potential influence of age (≤64 vs. ≥65 yr) and the type of treatment modality (primary, salvage, or total laryngectomy with radiotherapy) on outcomes. Our final study population was made up of 34 patients—31 men and 3 women, aged 49 to 89 years (mean: 66.8)— who had undergone a total laryngectomy. One year after surgery, all patients were asked to complete the M.D. Anderson dysphagia inventory (MDADI), which quantifies swallowing function and swallowing-related QOL, and the University of Washington quality-of-life questionnaire (UW-QOL), which quantifies overall QOL. Of the 34 patients, 16 had undergone a horizontal surgical closure of their neo-pharynx and 18 a vertical closure. According to the MDADI, patients in the horizontal group experienced significantly better swallowing function/QOL; the mean composite MDADI scores were 91.5 in the horizontal group and 68.3 in the vertical group (p = 0.005). We found no significant difference in terms of overall QOL, as the respective mean UW-QOL scores were 81.0 and 80.8 (p = 0.93). The population correlation coefficient was positive in both groups, but more so in the horizontal group (ρhorizontal = 0.876 and ρvertical = 0.676). Neither age nor the type of treatment modality employed influenced swallowing function/QOL (page = 0.10, ptreatment modality = 0.78) or overall QOL (page = 0.08, ptreatment modality = 0.59). We conclude that horizontal closure of the neo-pharynx is superior to vertical closure in terms postoperative swallowing function/QOL but not overall QOL.

scholarly journals Kepatuhan Diet dengan Kualitas Hidup Pasien Hemodialisa di RSUP Dr. Soeradji Tirtonegoro: Korelasi Studi

2020 ◽  
Vol 10 (2) ◽  
pp. 78-83
Author(s):  
Heru Ginanjar Triyono ◽  
Dian Novita K ◽  
Sugiarto Sugiarto ◽  
Tengku Isni Yuli ◽  
Winda Rofiyati
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
The Body ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Chi Square Test

Abstract Kidney is one the organs that has an important function in the body. These functions include regulating the concentration of salt in the blood, and regulating the balance of acid base and the excretion of excess salt.Design Of this study was analytic with total Random Sampling. Research that uses descriptive quantitative type using cross sectional. This researcher only observed and measured variables without giving treatment. Cross sectional design or cross-sectional study, researchers only make observations and measure variables at one time. The Sampling in this study. The sampling in this study were 30 respondents who underwent hemodialysis. The amount was obtained based on data on the number of patients. The results of the analysis of the relationship of diet adherence with the quality of life of hemodialysis patients at Hospital using the chi square test. From table 4.4 the chi suare correlation test results obtained sig (2-tailed) values ​​with the results of 0.003 p value <0.05 to 0.003 <0.05 showed a relationship between diet compliance with quality of life. Data generated from the bivariate analysis of respondents who comply with good quality of life were 14 respondents (66.7%), while respondents who were not compliant and with less quality of life were 4 respondents (44.4%). Key word: Diet, Kidney Failure, Quality Of Life, Hemodialysis  

Picture quality comparison between panoptic ophthalmoscope and non-mydriatic fundus camera

2020 ◽  
Vol 13 (4) ◽  
pp. 159-162
Author(s):  
Faisal Mehmood ◽  
Ahsan Mehmood ◽  
Awais Afzal ◽  
Abdullah Irfan ◽  
Muhammad Moin ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Fundus Photography ◽  
Picture Quality ◽  
High Definition ◽  
Chi Square ◽  
Cross Sectional ◽  
Fundus Camera ◽  
Significant Difference ◽  
Chi Square Test

ABSTRACT Background: Non-mydriatic fundus photography has been shown to be a potential alternative to direct ophthalmoscopy in the emergency department. Panoptic ophthalmoscope is a newer handheld alternative to non-mydriatic fundus camera. Its advantages include greater portability and lower price. Panoptic Ophthalmoscope compatibly utilizes mobile phone’s camera to capture high definition fundus photographs, however lower in quality in comparison with a fundus camera. This study compares the picture quality between panoptic ophthalmoscope (POO) and non-mydriatic fundus camera (NMFC). Patients and Methods: This comparative cross-sectional study was conducted in Lahore General Hospital, Lahore. Three twenty three (323) fundus pictures were taken from two different cameras. One hundred sixty pictures (160) were taken with NMFC and one hundred sixty three (163) with POO. Quality of each picture was assessed by two consultant ophthalmologists independently. The data was computed and analyzed by SPSS version 21. Chi square test was applied to the data. Confidence interval of 0.95 with α of 0.05 was taken. Results: There was statistically significant difference in picture quality of disc, macula, superior and inferior vascular arcades (p<0.001).  Total 122 out of 160 pictures taken by NMFC and 48 out of 163 pictures taken by POO were considered ideal by first ophthalmologist whereas 96 of 160 pictures taken by NMFC and none taken by POO were considered ideal by second ophthalmologist. Conclusion: Quality of images taken with NMFC is significantly better as compared to POO.

scholarly journals Evaluation of Malnutrition and Quality of Life in Patients Treated for Oral and Oropharyngeal Cancer

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Shruthi Pingili ◽  
Junaid Ahmed ◽  
Nanditha Sujir ◽  
Nandita Shenoy ◽  
Ravikiran Ongole
Keyword(s):  
Quality Of Life ◽  
Oropharyngeal Cancer ◽  
Cross Sectional Study ◽  
High Morbidity ◽  
Life Questionnaire ◽  
Chi Square ◽  
Cross Sectional ◽  
European Organization ◽  
Oral And Oropharyngeal Cancer

Background. Oral and oropharyngeal cancer is a debilitating disease with high morbidity and mortality. Depending on the site and extent of the involvement of the cancer and the type of treatment modality, these patients can develop pain, trismus, xerostomia, dysphagia, and taste disturbances, compromising them socially and nutritionally. The aim of the study was to evaluate malnutrition and quality of life in patients treated for oral and oropharyngeal cancer. Methodology. A cross-sectional study was conducted which included 97 patients treated for oral and oropharyngeal cancer. The quality of life of the selected patients was assessed by using a validated European Organization for the Research and Treatment of Cancer’s Quality of Life Questionnaire, Head and Neck and Mandibular Function Impairment Questionnaire. Pre- and posttreatment weight of the patients were assessed, and weight loss of ≥10% of pretreatment weight was considered as malnutrition. The chi-square test was used to correlate the symptoms with the quality of life. A paired t test was used to assess the differences in weight before and after treatment, and a p value of <0.005 was considered as significant. Results. The most commonly reported symptoms were xerostomia (93.81%), pain (81.44%), and dysphagia (76.3%). A total of 40.2% of the individuals in the study had malnutrition. Malnutrition was comparatively lower in the group who had nutritional supplements. Conclusion. The quality of life in patients treated for oral and oropharyngeal cancer deteriorates immediately after the treatment; however, it significantly improves over time.

scholarly journals The quality of life of disease-free Brazilian breast cancer survivors

2013 ◽  
Vol 47 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Priscila Bernardina Miranda Soares ◽  
Jair Almeida Carneiro ◽  
Leandro Augusto Rocha ◽  
Renata Cristina Ribeiro Gonçalves ◽  
Daniella Reis Barbosa Martelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Breast Cancer Survivors ◽  
Linear Models ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Multivariate Linear Models

The objective of this study was to compare the quality of life of women who survived breast cancer and women who have not had the disease, and to identify associated factors. It is cross-sectional study in which the comparison group includes survivors of breast cancer aged between 40 and 69 years. One hundred and fifty-four women were included, 70 with breast cancer and 84 without the disease. The SF-36 was used to evaluate quality of life. The chi-square test and multivariate linear models were used to compare the groups. The estimated mean physical and mental components were significantly better for the group who survived the disease (51.10 and 52.25, respectively) compared to the group without cancer (47.26 and 47.93, respectively). The study indicates that survivors of breast cancer had a better quality of life compared to women without the disease.

scholarly journals QUALITY OF LIFE EVALUATION AND ASSOCIATED FACTORSIN ASTHMATIC CHILDREN AND ADOLESCENTS ATTENDED IN A SPECIALIZED OUTPATIENT CLINIC

2020 ◽  
Vol 38 ◽  
Author(s):  
Fernanda Chedid de Souza Fontan ◽  
Sérgio Wilson Duwe ◽  
Karoliny dos Santos ◽  
Jane da Silva
Keyword(s):  
Quality Of Life ◽  
Disease Control ◽  
Children And Adolescents ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Adherence To Treatment ◽  
Chi Square ◽  
Cross Sectional

ABSTRACT Objective: To evaluate the quality of life and its association with disease control, severity, allergic comorbidities and adherence to treatment in children and adolescents with asthma. Methods: A cross-sectional study that included children and adolescents aged seven to 17. The Paediatric Asthma Quality of Life Questionnaire (PAQLQ) was used to assess their quality of life. Sociodemographic and clinical data were obtained from the chart and from a questionnaire. Descriptive statistics were performed and chi-square or Fisher’s exact tests were used to verify the existence of associations between quality of life and disease control, severity, comorbidities and adherence to treatment. The level of statistical significance was set at p<0.05. Results: 101 children/adolescents were evaluated (62.4% boys), with a mean age of 10.1 years. On average, the PAQLQ score was ≤5.9 points, indicating moderate / severe quality of life impairment. Higher levels of control, as well as higher disease severity, were associated with higher quality of life impairment, both in total PAQLQ score and domains (p<0.05). The presence of comorbidities was also associated with higher quality of life impairment (p=0.01), except in the emotional function domain. Adherence to treatment showed no association with quality of life. Conclusions: Children and adolescents with asthma present impairment in their quality of life, and this is related to poorer control and severity of the disease, as well as to the presence of allergic comorbidities.

scholarly journals Assessment of Different Areas of Perforation While Performing RCT

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 233-238
Author(s):  
Keerthiga Nagarajan ◽  
Iffat Nasim ◽  
Arthi B
Keyword(s):  
Root Canal ◽  
Root Surface ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference ◽  
Chi Square Test ◽  
Root Canal System ◽  
Level Of Significance

Root perforation is defined as an iatrogenic or pathological communication between the root canal system and the external tooth/root surface. They may be pathologic or iatrogenic in etiology. Iatrogenic perforations during root canal therapy account for a large portion of endodontic failures and may necessitate the need for extraction. Assessing the sites commonly perforated helps anticipate such complications and thereby formulate means to improve the quality of treatment offered. This study aims to assess the different areas of perforation while performing root canal treatment. A retrospective cross-sectional study was conducted using the patient records from the OPD of Saveetha Dental College, Chennai from June 2019 to April 2020, and patients above the age of 18 years who underwent perforation management were selected by non-probability sampling. Data was collected and then subjected to statistical analysis using Statistical Package for Social Science for Windows (version 20.0, SPSS Inc., Chicago Ill., USA). Chi-square test was employed with a level of significance set at p<0.05. It was found that the most common site of perforation was the furcation area (50%), followed by crown perforations (44.1%). There were more males (52.9%) who experienced perforations than females and the most common age group was 35-55 years (50%). There was a significant difference between the site of perforation and tooth involved (p=0.032). There also was a significant difference between the perforation site and the arch involved (p=0.044). The most commonly perforated tooth was found to be mandibular molars.

scholarly journals Diabetes knowledge, risk perception, and quality of life among South Asian caregivers in young adulthood

2020 ◽  
Vol 8 (2) ◽  
pp. e001268
Author(s):  
Angela Koipuram ◽  
Sandra Carroll ◽  
Zubin Punthakee ◽  
Diana Sherifali
Keyword(s):  
Quality Of Life ◽  
Risk Perception ◽  
South Asian ◽  
Online Survey ◽  
Educational Interventions ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Design And Methods

IntroductionPersons of South Asian descent have a higher prevalence of type 2 diabetes mellitus (T2DM). The management of T2DM in the South Asian community has required the support of adult children, potentially impacting the quality of life, diabetes-related knowledge, and risk perception among these caregivers.Research design and methodsTo investigate diabetes-related knowledge, quality of life, risk perception, and actual risk of developing diabetes among South Asian young adults whose parents are living with T2DM. A cross-sectional study was conducted (n=150). An online survey was administered. Data were analyzed with descriptive and inferential statistics.ResultsThere was a statistically significant difference in diabetes-related knowledge between males and females (p<0.001). Males (in comparison to females) had a lower risk perception of developing diabetes (p=0.06). Further, risk perception and diabetes-related knowledge were positively associated with caregiver’s physical health (p=0.002).ConclusionFindings highlight the importance of providing gender-specific and culturally tailored diabetes educational interventions.

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