scholarly journals A Convolutional Neural Network Classifier VGG-19 Architecture for Lesion Detection and Grading in Diabetic Retinopathy Based on Deep Learning

2020 ◽  
Vol 66 (1) ◽  
pp. 827-842
Author(s):  
V. Sudha ◽  
Dr. T. R. Ganeshbabu
Entropy ◽  
2021 ◽  
Vol 23 (7) ◽  
pp. 816
Author(s):  
Pingping Liu ◽  
Xiaokang Yang ◽  
Baixin Jin ◽  
Qiuzhan Zhou

Diabetic retinopathy (DR) is a common complication of diabetes mellitus (DM), and it is necessary to diagnose DR in the early stages of treatment. With the rapid development of convolutional neural networks in the field of image processing, deep learning methods have achieved great success in the field of medical image processing. Various medical lesion detection systems have been proposed to detect fundus lesions. At present, in the image classification process of diabetic retinopathy, the fine-grained properties of the diseased image are ignored and most of the retinopathy image data sets have serious uneven distribution problems, which limits the ability of the network to predict the classification of lesions to a large extent. We propose a new non-homologous bilinear pooling convolutional neural network model and combine it with the attention mechanism to further improve the network’s ability to extract specific features of the image. The experimental results show that, compared with the most popular fundus image classification models, the network model we proposed can greatly improve the prediction accuracy of the network while maintaining computational efficiency.


2021 ◽  
Vol 8 (3) ◽  
pp. 619
Author(s):  
Candra Dewi ◽  
Andri Santoso ◽  
Indriati Indriati ◽  
Nadia Artha Dewi ◽  
Yoke Kusuma Arbawa

<p>Semakin meningkatnya jumlah penderita diabetes menjadi salah satu faktor penyebab semakin tingginya penderita penyakit <em>diabetic retinophaty</em>. Salah satu citra yang digunakan oleh dokter mata untuk mengidentifikasi <em>diabetic retinophaty</em> adalah foto retina. Dalam penelitian ini dilakukan pengenalan penyakit diabetic retinophaty secara otomatis menggunakan citra <em>fundus</em> retina dan algoritme <em>Convolutional Neural Network</em> (CNN) yang merupakan variasi dari algoritme Deep Learning. Kendala yang ditemukan dalam proses pengenalan adalah warna retina yang cenderung merah kekuningan sehingga ruang warna RGB tidak menghasilkan akurasi yang optimal. Oleh karena itu, dalam penelitian ini dilakukan pengujian pada berbagai ruang warna untuk mendapatkan hasil yang lebih baik. Dari hasil uji coba menggunakan 1000 data pada ruang warna RGB, HSI, YUV dan L*a*b* memberikan hasil yang kurang optimal pada data seimbang dimana akurasi terbaik masih dibawah 50%. Namun pada data tidak seimbang menghasilkan akurasi yang cukup tinggi yaitu 83,53% pada ruang warna YUV dengan pengujian pada data latih dan akurasi 74,40% dengan data uji pada semua ruang warna.</p><p> </p><p><em><strong>Abstract</strong></em></p><p class="Abstract"><em>Increasing the number of people with diabetes is one of the factors causing the high number of people with diabetic retinopathy. One of the images used by ophthalmologists to identify diabetic retinopathy is a retinal photo. In this research, the identification of diabetic retinopathy is done automatically using retinal fundus images and the Convolutional Neural Network (CNN) algorithm, which is a variation of the Deep Learning algorithm. The obstacle found in the recognition process is the color of the retina which tends to be yellowish red so that the RGB color space does not produce optimal accuracy. Therefore, in this research, various color spaces were tested to get better results. From the results of trials using 1000 images data in the color space of RGB, HSI, YUV and L * a * b * give suboptimal results on balanced data where the best accuracy is still below 50%. However, the unbalanced data gives a fairly high accuracy of 83.53% with training data on the YUV color space and 74,40% with testing data on all color spaces.</em></p><p><em><strong><br /></strong></em></p>


2021 ◽  
Vol 11 (1) ◽  
pp. 480-490
Author(s):  
Asha Gnana Priya Henry ◽  
Anitha Jude

Abstract Retinal image analysis is one of the important diagnosis methods in modern ophthalmology because eye information is present in the retina. The image acquisition process may have some effects and can affect the quality of the image. This can be improved by better image enhancement techniques combined with the computer-aided diagnosis system. Deep learning is one of the important computational application techniques used for a medical imaging application. The main aim of this article is to find the best enhancement techniques for the identification of diabetic retinopathy (DR) and are tested with the commonly used deep learning techniques, and the performances are measured. In this article, the input image is taken from the Indian-based database named as Indian Diabetic Retinopathy Image Dataset, and 13 filters are used including smoothing and sharpening filters for enhancing the images. Then, the quality of the enhancement techniques is compared using performance metrics and better results are obtained for Median, Gaussian, Bilateral, Wiener, and partial differential equation filters and are combined for improving the enhancement of images. The output images from all the enhanced filters are given as the convolutional neural network input and the results are compared to find the better enhancement method.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Shu-I Pao ◽  
Hong-Zin Lin ◽  
Ke-Hung Chien ◽  
Ming-Cheng Tai ◽  
Jiann-Torng Chen ◽  
...  

Deep learning of fundus photograph has emerged as a practical and cost-effective technique for automatic screening and diagnosis of severer diabetic retinopathy (DR). The entropy image of luminance of fundus photograph has been demonstrated to increase the detection performance for referable DR using a convolutional neural network- (CNN-) based system. In this paper, the entropy image computed by using the green component of fundus photograph is proposed. In addition, image enhancement by unsharp masking (UM) is utilized for preprocessing before calculating the entropy images. The bichannel CNN incorporating the features of both the entropy images of the gray level and the green component preprocessed by UM is also proposed to improve the detection performance of referable DR by deep learning.


Author(s):  
Alejandro Lopez-Rincon ◽  
Alberto Tonda ◽  
Lucero Mendoza-Maldonado ◽  
Daphne G.J.C. Mulders ◽  
Richard Molenkamp ◽  
...  

ABSTRACTIn this paper, deep learning is coupled with explainable artificial intelligence techniques for the discovery of representative genomic sequences in SARS-CoV-2. A convolutional neural network classifier is first trained on 553 sequences from available repositories, separating the genome of different virus strains from the Coronavirus family with considerable accuracy. The network’s behavior is then analyzed, to discover sequences used by the model to identify SARS-CoV-2, ultimately uncovering sequences exclusive to it. The discovered sequences are first validated on samples from other repositories, and proven able to separate SARS-CoV-2 from different virus strains with near-perfect accuracy. Next, one of the sequences is selected to generate a primer set, and tested against other state-of-the-art primer sets on existing datasets, obtaining competitive results. Finally, the primer is synthesized and tested on patient samples (n=6 previously tested positive), delivering a sensibility similar to routine diagnostic methods, and 100% specificity. In this paper, deep learning is coupled with explainable artificial intelligence techniques for the discovery of representative genomic sequences in SARS-CoV-2. A convolutional neural network classifier is first trained on 553 sequences from NGDC, separating the genome of different virus strains from the Coronavirus family with accuracy 98.73%. The network’s behavior is then analyzed, to discover sequences used by the model to identify SARS-CoV-2, ultimately uncovering sequences exclusive to it. The discovered sequences are validated on samples from NCBI and GISAID, and proven able to separate SARS-CoV-2 from different virus strains with near-perfect accuracy. Next, one of the sequences is selected to generate a primer set, and tested against other state-of-the-art primer sets, obtaining competitive results. Finally, the primer is synthesized and tested on patient samples (n=6 previously tested positive), delivering a sensibility similar to routine diagnostic methods, and 100% specificity. The proposed methodology has a substantial added value over existing methods, as it is able to both identify promising primer sets for a virus from a limited amount of data, and deliver effective results in a minimal amount of time. Considering the possibility of future pandemics, these characteristics are invaluable to promptly create specific detection methods for diagnostics.


2019 ◽  
Vol 29 (7) ◽  
pp. 3338-3347 ◽  
Author(s):  
Charlie A. Hamm ◽  
Clinton J. Wang ◽  
Lynn J. Savic ◽  
Marc Ferrante ◽  
Isabel Schobert ◽  
...  

2021 ◽  
Author(s):  
Abdelali ELMOUFIDI ◽  
Hind Amoun

Abstract Classification of the stages of diabetic retinopathy (DR) is considered a key step in the assessment and management of diabetic retinopathy. Due to the damage caused by high blood sugar to the retinal blood vessels, different microscopic structures can be occupied in the retinal area, such as micro-aneurysms, hard exudate and neovascularization. The convolutional neural network (CNN) based on deep learning has become a promising method for the analysis of biomedical images. In this work, representative images of diabetic retinopathy (DR) are divided into five categories according to the professional knowledge of ophthalmologists. This article focuses on the use of convolutional neural networks to classify background images of DR according to disease severity and on the application of pooling, Softmax Activation to achieve greater accuracy. The aptos2019-blindness-detection database makes it possible to verify the performance of the proposed algorithm.


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