scholarly journals Effects of Hibiscus Rosasinensis on the Hematology of the Swiss Albino Mice: An In-Vivo Study

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Blood Cell ◽  
Research Study ◽  
Chemical Constituents ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Medicinal Uses ◽  
Swiss Albino Mice ◽  
Plant Parts ◽  
Albino Mice

The present research/study was conducted on the heamtology of the Swiss albino mice irrespective of sex and experiment was done by using the aqueous extract of Hibiscus rosasinensis. Nature has become a vital source of medicine nowadays and people are also becoming very much dependent on the herbal drugs. Hibiscus rosasinensis is a very common and renowned plant having a variety of medicinal uses. This plant parts (flower, leaf and shrub etc.) possesses many phytochemicals which have different medicinal values. But these chemical constituents whether affect the hematological parameters (Red Blood Cell, White Blood Cell, Hemoglobin Concentration and Packed Cell Volume) is yet to know. For the sake of this purpose the experiment was done. Hence, it is concluded that the use of Hibiscus rosasinensis whereas may not cause any adverse effect on the hematology of the rather it elevates the hematological parameters of Swiss albino mice.

scholarly journals Vitamin-C Treated Haematology Assessment of Swiss Albino Mice (Mus musculus)

2020 ◽  
Vol 11 (2) ◽  
pp. 9044-9050
Keyword(s):  
Vitamin C ◽  
Blood Cell ◽  
Cell Count ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
The Body ◽  
Blood Cell Count ◽  
Swiss Albino Mice ◽  
Positive Effects ◽  
Albino Mice

Vitamin C is an essential dietary supplement that plays a vital role in battling health conditions. The antioxidant has positive effects on the functioning of the body. The purpose of this study is to investigate the outcome of varying concentrations of Vitamin C on the hematological parameters of Swiss Albino mice. Four albino mice were separated and accommodated in similar caging conditions. Three of them were orally administered with 250mg/kg, 500mg/kg, and 1000mg/kg Vitamin C powder, along with their diet. The fourth one was kept as control, in order to provide a standard value for future comparison. After 30 days of administration of the Vitamin C, the red blood cell count, the white blood cell count, the hemoglobin concentration, the platelet cell count, and the packed cell volume of the blood samples were tested.

Effects of 10-GHz Microwaves on Hematological Parameters in Swiss Albino Mice and Their Modulation by Prunus avium

2013 ◽  
Vol 32 (3) ◽  
pp. 205-217
Author(s):  
Rashmi Sisodia ◽  
Faiza Rifat ◽  
Archana Sharma ◽  
Preeti Srivastava ◽  
K. V. Sharma
Keyword(s):  
Prunus Avium ◽  
Hematological Parameters ◽  
Swiss Albino Mice ◽  
Albino Mice

DNA damage and repair after exposure to sevoflurane in vivo, evaluated in Swiss albino mice by the alkaline comet assay and micronucleus test

2010 ◽  
Vol 51 (1) ◽  
pp. 79-86 ◽  
Author(s):  
G. Brozovic ◽  
N. Orsolic ◽  
R. Rozgaj ◽  
V. Kasuba ◽  
F. Knezevic ◽  
...  
Keyword(s):  
Dna Damage ◽  
Comet Assay ◽  
Micronucleus Test ◽  
Alkaline Comet Assay ◽  
Dna Damage And Repair ◽  
Swiss Albino Mice ◽  
Albino Mice

scholarly journals In vivo antiplasmodial properties of fractions and flavonoids of Pseudarthria hooheri Wight & Arn. (Fabaceae)

2022 ◽  
Author(s):  
Joseph Tchamgoue ◽  
Amelework N. Eyado ◽  
Boniface P. Kamdem Kamdem ◽  
Yvan Anderson T. Ngandjui Ngandjui ◽  
Jean Claude Tchouankeu ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Malaria Treatment ◽  
Antiplasmodial Activity ◽  
Swiss Albino Mice ◽  
Treatment Situation ◽  
Healthy Female ◽  
Etoac Fraction ◽  
Albino Mice ◽  
Main Components

Malaria is regarded as one of the most lethal diseases. Resistance to artemisinin and its derivatives jeopardises effective malaria treatment. Finding novel antimalarial chemicals is critical given the existing treatment situation. This work aimed to examine the antiplasmodial capabilities of <i>Pseudarthria hookeri</i> fractions and flavonoids in vivo. The fractions and compounds antiplasmodial activity were evaluated on male Swiss albino mice infected with <i>Plasmodium berghei</i>, and on healthy female Swiss albino mice, the crude extract's acute toxicity was assessed. The EtOAc fraction had significant antiplasmodial activity (32.53 percent suppression at 500 mg/kg BW) and considerably prolonged the survival period of infected mice (9.8 days) compared to control mice (7.8 days). Parasitaemia was dramatically reduced (85.01, 59.41, and 70.39 percent), and the mean survival time extended (11.33, 10.00, and 9.33 days) with 15, 20 and 35 mg/kg of quercetin (<b>1</b>), 7-O-benzyl-6-prenylpinocembrin (<b>6</b>) and 6,8-diprenyleriodictyol (<b>11</b>) (isolates of the EtOAc fraction), respectively. BW loss and PCV reduction were also averted. Moreover, at 2500 mg/kg, the crude extract of <i>P. hookeri</i> showed no acute toxicity in mice. LC-MS analysis of the EtOAc fraction enabled the identification of nine flavonoids, with <b>8</b> and <b>11</b> being the main components. The present investigation confirmed <i>P. hookeri</i>'s antiplasmodial action, substantiating its ethnomedicinal application for malaria treatment.

scholarly journals In vivo glucose-6-phosphatase inhibitory, toxicity and antidiabetic potentials of 2-picolylamine thioureas in Swiss albino mice

2020 ◽  
Vol 27 (12) ◽  
pp. 3267-3273
Author(s):  
Sumaira Naz ◽  
Muhammad Zahoor ◽  
Muhammad Naveed Umar ◽  
Fatmah S. AlQahtany ◽  
Yousif M. Elnahas ◽  
...  
Keyword(s):  
Swiss Albino Mice ◽  
Albino Mice

Boric acid enhances in vivo Ehrlich ascites carcinoma cell proliferation in Swiss albino mice

Toxicology ◽  
2001 ◽  
Vol 165 (1) ◽  
pp. 1-11 ◽  
Author(s):  
S Qureshi ◽  
O.A Al-Shabanah ◽  
M.M Al-Harbi ◽  
A.M Al-Bekairi ◽  
M Raza
Keyword(s):  
Cell Proliferation ◽  
Boric Acid ◽  
Carcinoma Cell ◽  
Ehrlich Ascites Carcinoma ◽  
Ehrlich Ascites Carcinoma Cell ◽  
Swiss Albino Mice ◽  
Ehrlich Ascites ◽  
Albino Mice

scholarly journals Dinuclear ruthenium(II) Schiff base complex: a first in vivo study in Swiss albino mice

2019 ◽  
Vol 120 (01) ◽  
pp. 26-34 ◽  
Author(s):  
V. Muzika ◽  
S. Custovic ◽  
S. Alicelebic ◽  
E. Cosovic ◽  
A. Zahirovic ◽  
...  
Keyword(s):  
Schiff Base ◽  
Schiff Base Complex ◽  
In Vivo Study ◽  
Swiss Albino Mice ◽  
Base Complex ◽  
Dinuclear Ruthenium ◽  
Albino Mice
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