scholarly journals Intralesional Steroid Injection for Primary Chalazion in Adults

2020 ◽  
Vol 5 (3) ◽  
Keyword(s):  
Triamcinolone Acetonide ◽  
Treatment Option ◽  
Granulomatous Inflammation ◽  
Meibomian Gland ◽  
Alternative Treatment Option ◽  
Vertical Incision ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Upper Lid ◽  
Gland Duct

Background: Chalazion (Meibomian cyst) a chronic lipo-granulomatous inflammation seconday to retention of sebum caused by obstruction of Meibomian gland duct of unknown cause. It is manifested by localized painless swelling in upper or lower lid usually points towards conjunctival side of lid (to be differentiated from stye). Vary in presentation from a small painless nodule self-limiting to a painful lid swelling complicated by corneal astigmatism and mechanical ptosis. Treatment option in case 2ry infection is hot compresses and topical antibiotic and if large surgery excision (vertical incision into the tarsal gland from conjunctiva surface). Injection of steroid (Triamcinolone) inside Chalazion considered as alternative treatment option with high success rate particularly in patients where incision and curette is difficult to perform due to poor patient’s cooperation. Or risk of lacrimal passage injury when the lesion located near to it... The aim of this study is to assess the effectiveness of intralesional triamcinolone acetonide (TA) injection for the treatment of primary chalazion in adults. Methods: 24 adult Patients mean age 38.6 ± 13.2 years with primary chalazion subjected to intralesional triamcinolone injection as management of primary chalazion. 0.05 to 0.15mL of triamcinolone injected into the center of the chalazion transconjunctivally in three patients the eversion of the upper lid were difficult and the injection was given transcutaneous. Result: 15 females and 9 males were included in this study. right eye was more affected than the left side14/10 respectively in all cases chalazion locate in the upper lid, mean chalazion size 0.74 ± 0.4 mm², time for complete resolution of the chalazion17.5 ± 12.0 days. There were no significant complications reported from this procedure Conclusion: Intralesional triamcinolone acetonide (TA) injection for the treatment of primary chalazion in adult was effective and without any significant complications.

scholarly journals Life-Threatening Subglottic Stenosis of Granulomatosis with Polyangiitis: A Case Report

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 423
Author(s):  
Jin An ◽  
Jae-Won Song
Keyword(s):  
Immunosuppressive Therapy ◽  
Granulomatosis With Polyangiitis ◽  
Granulomatous Inflammation ◽  
Subglottic Stenosis ◽  
Emergency Tracheostomy ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Life Threatening ◽  
Carbon Dioxide Co2 ◽  
Laryngotracheal Resection

Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by necrotizing granulomatous inflammation. Subglottic stenosis, which is defined as narrowing of the airway below the vocal cords, has a frequency of 16–23% in GPA. Herein, we present the case of a 39-year-old woman with subglottic stenosis manifesting as life-threatening GPA, which was recurrent under systemic immunosuppressive therapy. The patient underwent an emergency tracheostomy, intratracheal intervention, such as carbon dioxide (CO2) laser surgery and intralesional steroid injection via laryngomicroscopic surgery, and laryngotracheal resection with remodeling. Severe subglottic stenosis treatment requires active intratracheal intervention, surgery, and systemic immunosuppressive therapy.

scholarly journals Comparative Study of Surgical Treatment of Chalazion

2015 ◽  
Vol 9 (2) ◽  
pp. 68-69
Author(s):  
Khandaker Anowar Hossain ◽  
Md Abdur Rashid ◽  
AKM Rafiqul Islam
Keyword(s):  
Inflammatory Lesion ◽  
Skin Surface ◽  
Meibomian Gland ◽  
Medical College ◽  
Large Size ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Group A ◽  
Group B

A chalazion is chronic lipogranulomatous inflammatory lesion caused by blockage of meibomian gland orifices & stagnation of sebaceous secretion. Common practices in treatment of chalazion are intralesional steroid injection, incision & curettage and excision of chalazion. Recurrence rate is high for incision & curettage in case of large chalazion. The aim of the study is to established that excision large chalazion give better result than incision & curettage. The study was carried out at Diabetic Association Medical College & Hospital, Faridpur and General Hospital, Fadidpur. A total 100 cases were selected for study. Technique of operation were incision & curettage through conjunctival surface and excision of chalazion through skin surface. In 50 % cases we performed incision & curettage both in small (size <5mm) and large (size >5mm) chalazion. In 50 % cases of large chalazion we performed excision of chalazion. The follow up period was 3 months to 6 months. In group -A with incision & curettage through conjunctival surface, in case of small chalazion 27 out of 30 patients were cured (90%). In case of large chalazion 14 out of 20 patients were cured (70%). In group B with excision of chalazion through skin surface, in case of large chalazion 49 out of 50 patients were cured (98%). So higher success rate after excision of large chalazion through skin surface.Faridpur Med. Coll. J. 2014;9(2): 68-69

scholarly journals Comparison of Intralesional Kenacort Injection Versus Surgical Intervention for Primary Chalazion

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Narain Das, Asma Shams Beenish Khan Muhammad Nasir Bhatti
Keyword(s):  
Triamcinolone Acetonide ◽  
Complete Resolution ◽  
Surgical Intervention ◽  
Female Ratio ◽  
Medical College ◽  
Group I ◽  
Department Of Ophthalmology ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Group 2

Purpose: To compare the efficacy and safety of intralesional steroid injection versus surgical intervention (Incision and Curettage) in Primary Chalazion. Study Design: Prospective, comparative and interventional hospital based study. Place and Duration of Study: Shaheed Mohtarma Benazir Bhutto Medical College Lyari and Sindh Government Lyari General Hospital, Karachi from 15th October, 2016 to 15th April, 2017. Material and Methods: All patients diagnosed with chalazion on clinical basis from the Outpatient department of Ophthalmology were included in the study. All patients were randomly divided into two groups with 25 patients in each group. Group 1 received intralesional 0.2 ml triamcinolone acetonide while Group 2 received surgical intervention (Incision and Curettage). Results: There were 50 eyes of 50 patients between the age group of 15 to 40 years and of either gender. Mean age was 25 � 12.2 with male to female ratio of 2:1. There were 19 (76%) patients who achieved complete resolution of chalazion after intra-lesional triamcinolone acetonide in group I and there were 21 (84%) patients out of 25 who achieved complete resolution of chalazion after incision and curettage in group II. No ocular complication such as bleeding, elevation of intra ocular pressure, eye lid de-pigmentation or any loss of vision in either group was observed. Conclusion: Intralesional triamcinolone acetonide injection is nearly as effective as surgical treatment (incision and curettage) in primary chalazion. Keywords: Triamcinolone, Chalazion, Eyelid Diseases.

scholarly journals A Study on Clinical Effect of Combined Pulsed Dye Laser And Intralesional Triamcinolone Acetonide in the Treatment of Keloid

2015 ◽  
Vol 23 (2) ◽  
pp. 234-238
Author(s):  
Quazi Salim Yazdi ◽  
Abdul Latif Khan ◽  
Md Sayeed Hasan ◽  
Imranul Hasan Murad
Keyword(s):  
Clinical Trial ◽  
Triamcinolone Acetonide ◽  
Dye Laser ◽  
Pulsed Dye Laser ◽  
Military Hospital ◽  
Medical College ◽  
Type Iv ◽  
Current Usage ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection

Keloids are common and cause functional and psychological morbidity. A wide variety of treatments, all in current usage, indicate that no treatment has been shown to be markedly superior to the others. This study was done using pulsed dye laser followed by more traditional intralesional steroid injection in the treatment of keloid. The aim of this study was to determine the effectiveness of the PDL in combination with intralesional triamcinolone acetonide (TCA) in the treatment of keloid and to elucidate possible side effects and complications. A prospective clinical trial was done in the Department of Dermatology & Venereology, Combined Military Hospital, Dhaka Cantonment, Dhaka, from December 2013 to February 2014. Adult patients of both sexes (Fitzpatric skin type IV & V) aged between 15 and 50 years with varying degree of keloids were randomly selected for the study. In this single-blinded clinical trial, 50 patients were randomly assigned and was irradiated by 595-nm flashlamp-pumped pulsed-dye laser (PDL, 5-7.5 J/cm2) at the 1st,4th, and 8th weeks and Intralesional steroid was given following PDL. Lesions were assessed for vascularity, pliability, pigmentation and height. The study showed an excellent improvement in nearly all measures, Good to excellent improvements (>76% improvement) were reported by 93% patient. Vancouver scar scale (0-14) decreased from 12.17 to a post treatment value of 3.41which is an excellent achievement. Results were reported by the blinded observer as follows: in vascularity (from 2.7 to 0.61), in pliability (from 3.9 to 1.1), in hyperpigmentation (from 2.4 to 0.92), in height (from 2.87 to 0.78).J Dhaka Medical College, Vol. 23, No.2, October, 2014, Page 234-238

scholarly journals Atypical Granulomatosis with Polyangiitis Presenting with Meibomitis, Scleritis, Uveitis and Papillary Bladder Tumor: A Case Report and Literature Review

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 680
Author(s):  
Takashi Kojima ◽  
Murat Dogru ◽  
Eisuke Shimizu ◽  
Hiroyuki Yazu ◽  
Aya Takahashi ◽  
...  
Keyword(s):  
Granulomatosis With Polyangiitis ◽  
Early Stage ◽  
Topical Steroid ◽  
Granulomatous Inflammation ◽  
Oral Prednisolone ◽  
Meibomian Gland ◽  
Clinical Findings ◽  
Meibomian Gland Dysfunction ◽  
Oral Steroids ◽  
Atypical Cells

Granulomatosis with polyangiitis (GPA) presents with a variety of systemic findings, sometimes with ocular findings initially, but is often difficult to diagnose at an early stage. An 85-year-old male had complaints of ocular dryness and redness and was diagnosed with meibomian gland dysfunction with meibomitis. Despite an initial treatment with topical steroid and antibiotics, the meibomitis did not improve and the left eye developed scleritis and iridocyclitis. The patient was administered topical mydriatics and oral steroids. During follow-up, the patient developed left hearing difficulty and reported a darker urine. Urinalysis revealed microscopic hematuria. A blood test showed an elevated erythrocyte sedimentation rate, positivity for perinuclear anti-neutorophil cytoplasmic antibody, and elevations in blood urea nitrogen and serum creatinine. Nasal mucosal biopsy showed a non-necrotizing granulomatous inflammation. Renal biopsy revealed focal glomerulosclerosis. Cystoscopy and bladder wash followed by a planned transurethral resection revealed atypical cells and apical papillary tumors which were resected. Iridocyclitis and scleritis responded well to oral prednisolone with 0.1% topical betamethasone and prednisolone ointment. The patient is tumor free with no recurrences 24 months after resection. GPA may present atypically with meibomian gland dysfunction without showing representative clinical findings. Early detection and treatment are essential for visual recovery.

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