scholarly journals Comparison of Intralesional Kenacort Injection Versus Surgical Intervention for Primary Chalazion

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Narain Das, Asma Shams Beenish Khan Muhammad Nasir Bhatti
Keyword(s):  
Triamcinolone Acetonide ◽  
Complete Resolution ◽  
Surgical Intervention ◽  
Female Ratio ◽  
Medical College ◽  
Group I ◽  
Department Of Ophthalmology ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Group 2

Purpose: To compare the efficacy and safety of intralesional steroid injection versus surgical intervention (Incision and Curettage) in Primary Chalazion. Study Design: Prospective, comparative and interventional hospital based study. Place and Duration of Study: Shaheed Mohtarma Benazir Bhutto Medical College Lyari and Sindh Government Lyari General Hospital, Karachi from 15th October, 2016 to 15th April, 2017. Material and Methods: All patients diagnosed with chalazion on clinical basis from the Outpatient department of Ophthalmology were included in the study. All patients were randomly divided into two groups with 25 patients in each group. Group 1 received intralesional 0.2 ml triamcinolone acetonide while Group 2 received surgical intervention (Incision and Curettage). Results: There were 50 eyes of 50 patients between the age group of 15 to 40 years and of either gender. Mean age was 25 � 12.2 with male to female ratio of 2:1. There were 19 (76%) patients who achieved complete resolution of chalazion after intra-lesional triamcinolone acetonide in group I and there were 21 (84%) patients out of 25 who achieved complete resolution of chalazion after incision and curettage in group II. No ocular complication such as bleeding, elevation of intra ocular pressure, eye lid de-pigmentation or any loss of vision in either group was observed. Conclusion: Intralesional triamcinolone acetonide injection is nearly as effective as surgical treatment (incision and curettage) in primary chalazion. Keywords: Triamcinolone, Chalazion, Eyelid Diseases.

scholarly journals To compare the efficacy and safety of intralesional kenacort injection vs surgical intervention (Incision and Curettage) in primary Chalazion

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
ND Pagarani Lohana
Keyword(s):  
General Hospital ◽  
Triamcinolone Acetonide ◽  
Complete Resolution ◽  
Surgical Intervention ◽  
Sampling Technique ◽  
Efficacy And Safety ◽  
Female Ratio ◽  
Medical College ◽  
Group I ◽  
Department Of Ophthalmology

ABSTRACT                                                                                                                 PURPOSE To compare the efficacy and safety of intralesional steroid injection versus surgical intervention (Incision and Curettage) in Primary Chalazion.   STUDY DESIGN A six months prospective, comparative and interventional hospital based study. PLACE AND DURATION OF STUDY Study was done at Shaheed Mohtarma Benazir Bhutto Medical College Lyari and Sindh Government Lyari General Hospital, Karachi. Duration of study was six months from 15th October, 2016 to 15th April, 2017.   MATERAILS AND METHODS   This was a Prospective, Comparative, Interventional study with the use of probability sampling technique. The Study was conducted at Shaheed Mohtarma Benazir Bhutto Medical College Lyari and Sindh Government Lyari General Hospital, Karachi for duration of six months from 15th October, 2016 to 15th April, 2017.   50 eyes of 50 patients between the age group of 15 to 40 years and of either gender diagnosed with chalazion on clinical basis from the Out patients department of Ophthalmology of Shaheed Mohtarma Benazir Bhutto Medical College Lyari were included in the study. All patients were randomly divided into two groups with 25 patients in each group. Group 1 received intralesional 0.2 ml triamcinolone acetonide while Group 2 received surgical intervention (Incision and Curettage).   RESULTS In a total of 50 patients the mean age was 25±12.2 with male to female ratio of 2:1. 19 (76%) patients achieved complete resolution of chalazion after intra lesional triamcinolone acetonide in group I and 21 (84%) patients out of 25 achieved complete resolution of chalazion after incision and curettage in group II. No ocular complication such as bleeding, elevation of intra ocular pressure, eye lid de-pigmentation or any loss of vision in either group was observed.   CONCLUSION Intra lesional triamcinolone acetonide injection is equally effective as incision and curettage in primary chalazion. It means it is a good alternative first line treatment in cases where diagnosis is straight forward.   KEYWORDS Intra Lesional Triamcinolone Acetonide, Surgical Intervention

scholarly journals A Study on Clinical Effect of Combined Pulsed Dye Laser And Intralesional Triamcinolone Acetonide in the Treatment of Keloid

2015 ◽  
Vol 23 (2) ◽  
pp. 234-238
Author(s):  
Quazi Salim Yazdi ◽  
Abdul Latif Khan ◽  
Md Sayeed Hasan ◽  
Imranul Hasan Murad
Keyword(s):  
Clinical Trial ◽  
Triamcinolone Acetonide ◽  
Dye Laser ◽  
Pulsed Dye Laser ◽  
Military Hospital ◽  
Medical College ◽  
Type Iv ◽  
Current Usage ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection

Keloids are common and cause functional and psychological morbidity. A wide variety of treatments, all in current usage, indicate that no treatment has been shown to be markedly superior to the others. This study was done using pulsed dye laser followed by more traditional intralesional steroid injection in the treatment of keloid. The aim of this study was to determine the effectiveness of the PDL in combination with intralesional triamcinolone acetonide (TCA) in the treatment of keloid and to elucidate possible side effects and complications. A prospective clinical trial was done in the Department of Dermatology & Venereology, Combined Military Hospital, Dhaka Cantonment, Dhaka, from December 2013 to February 2014. Adult patients of both sexes (Fitzpatric skin type IV & V) aged between 15 and 50 years with varying degree of keloids were randomly selected for the study. In this single-blinded clinical trial, 50 patients were randomly assigned and was irradiated by 595-nm flashlamp-pumped pulsed-dye laser (PDL, 5-7.5 J/cm2) at the 1st,4th, and 8th weeks and Intralesional steroid was given following PDL. Lesions were assessed for vascularity, pliability, pigmentation and height. The study showed an excellent improvement in nearly all measures, Good to excellent improvements (>76% improvement) were reported by 93% patient. Vancouver scar scale (0-14) decreased from 12.17 to a post treatment value of 3.41which is an excellent achievement. Results were reported by the blinded observer as follows: in vascularity (from 2.7 to 0.61), in pliability (from 3.9 to 1.1), in hyperpigmentation (from 2.4 to 0.92), in height (from 2.87 to 0.78).J Dhaka Medical College, Vol. 23, No.2, October, 2014, Page 234-238

scholarly journals Treatment of Chalazian: a Comparative Cross-sectional Study

2019 ◽  
Vol 1 (1) ◽  
pp. 5-9
Author(s):  
Binita Bhattarai ◽  
Koshal Shrestha ◽  
Sushila Patel ◽  
Laxmi Devi Manandhar ◽  
Rosy Karki ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Complete Resolution ◽  
Cross Sectional Study ◽  
Meibomian Gland ◽  
Intralesional Injection ◽  
Cross Sectional ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Eye Symptoms

Background: Chalazion is a common eyelid disease caused by plugged meibomian glands and chronic lipogranulomatous inflammation. It can affect individuals of all ages and may cause local eye symptoms such as irritation and inflammation and cosmetic disfigurement. There are mainly three methods of treating chalazion: Intralesional Triamcinolone Acetonide (0.1-0.3 ml of 40mg/ml), Incision and Curettage and Conservative Treatment (hot compression +lid hygiene + antibiotic ointment) to the affected eyelid. To comparing which method is the best this study has been carried out Methodology: Patients with chalazion presenting to OPD from 15 March to 15 July 2017 were included in the study. They underwent any of the three procedures according to their choice. Follow up visit was done at two weeks to determine effectiveness in terms of reduction of size or complete resolution of the chalazion. Results: Out of 112 patients enrolled in study 65(58%) were females and 47(42%) were male with a male: female ratio of (0.7:1). The mean age of involvement was 25.7years (SD 10.3). At 2 weeks follow up there was complete resolution in incision and curettage (I and C) group 77 %( 41/53) and in Triamcinolone Acetonide (TA) injection group 63 %( 20/32). Pearsons correlations showed that I and C were superior to any other forms of intervention for any size of chalazion followed by intralesional injection of TA. Conclusion: Among the three methods, Incision and Curettage remained the best choice for treatment of chalazion followed by triamcinolone acetonide injection but may need multiple injections. Keywords: Chalazion, Intralesional Triamcinolone, Incision and Curettage, Meibomian Gland

scholarly journals Comparative Study of Surgical Treatment of Chalazion

2015 ◽  
Vol 9 (2) ◽  
pp. 68-69
Author(s):  
Khandaker Anowar Hossain ◽  
Md Abdur Rashid ◽  
AKM Rafiqul Islam
Keyword(s):  
Inflammatory Lesion ◽  
Skin Surface ◽  
Meibomian Gland ◽  
Medical College ◽  
Large Size ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Group A ◽  
Group B

A chalazion is chronic lipogranulomatous inflammatory lesion caused by blockage of meibomian gland orifices & stagnation of sebaceous secretion. Common practices in treatment of chalazion are intralesional steroid injection, incision & curettage and excision of chalazion. Recurrence rate is high for incision & curettage in case of large chalazion. The aim of the study is to established that excision large chalazion give better result than incision & curettage. The study was carried out at Diabetic Association Medical College & Hospital, Faridpur and General Hospital, Fadidpur. A total 100 cases were selected for study. Technique of operation were incision & curettage through conjunctival surface and excision of chalazion through skin surface. In 50 % cases we performed incision & curettage both in small (size <5mm) and large (size >5mm) chalazion. In 50 % cases of large chalazion we performed excision of chalazion. The follow up period was 3 months to 6 months. In group -A with incision & curettage through conjunctival surface, in case of small chalazion 27 out of 30 patients were cured (90%). In case of large chalazion 14 out of 20 patients were cured (70%). In group B with excision of chalazion through skin surface, in case of large chalazion 49 out of 50 patients were cured (98%). So higher success rate after excision of large chalazion through skin surface.Faridpur Med. Coll. J. 2014;9(2): 68-69

scholarly journals Intralesional Steroid Injection for Primary Chalazion in Adults

2020 ◽  
Vol 5 (3) ◽  
Keyword(s):  
Triamcinolone Acetonide ◽  
Treatment Option ◽  
Granulomatous Inflammation ◽  
Meibomian Gland ◽  
Alternative Treatment Option ◽  
Vertical Incision ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Upper Lid ◽  
Gland Duct

Background: Chalazion (Meibomian cyst) a chronic lipo-granulomatous inflammation seconday to retention of sebum caused by obstruction of Meibomian gland duct of unknown cause. It is manifested by localized painless swelling in upper or lower lid usually points towards conjunctival side of lid (to be differentiated from stye). Vary in presentation from a small painless nodule self-limiting to a painful lid swelling complicated by corneal astigmatism and mechanical ptosis. Treatment option in case 2ry infection is hot compresses and topical antibiotic and if large surgery excision (vertical incision into the tarsal gland from conjunctiva surface). Injection of steroid (Triamcinolone) inside Chalazion considered as alternative treatment option with high success rate particularly in patients where incision and curette is difficult to perform due to poor patient’s cooperation. Or risk of lacrimal passage injury when the lesion located near to it... The aim of this study is to assess the effectiveness of intralesional triamcinolone acetonide (TA) injection for the treatment of primary chalazion in adults. Methods: 24 adult Patients mean age 38.6 ± 13.2 years with primary chalazion subjected to intralesional triamcinolone injection as management of primary chalazion. 0.05 to 0.15mL of triamcinolone injected into the center of the chalazion transconjunctivally in three patients the eversion of the upper lid were difficult and the injection was given transcutaneous. Result: 15 females and 9 males were included in this study. right eye was more affected than the left side14/10 respectively in all cases chalazion locate in the upper lid, mean chalazion size 0.74 ± 0.4 mm², time for complete resolution of the chalazion17.5 ± 12.0 days. There were no significant complications reported from this procedure Conclusion: Intralesional triamcinolone acetonide (TA) injection for the treatment of primary chalazion in adult was effective and without any significant complications.

scholarly journals Comparison of efficacy between intrathecal nalbuphine and fentanyl as adjuvant to hyperbaric bupivacaine for perianal surgery

2021 ◽  
Vol 53 (1-2) ◽  
pp. 27-30
Author(s):  
Moslema Parvin ◽  
Anjuman Ara ◽  
Kazi Nurjahan ◽  
Lipika Roy ◽  
Lailatunnessa
Keyword(s):  
Side Effects ◽  
Motor Block ◽  
Hyperbaric Bupivacaine ◽  
Duration Of Action ◽  
Female Ratio ◽  
Medical College ◽  
Group I ◽  
Duration Of Surgery ◽  
Group Ii ◽  
American Society

Background: Intrathecal opioids enhance the duration of action of local anasthetic drugs. Both nalpuphine and fentanyl enhance the action of hyperbaric bupivacaine when introduced intrathecally as adjuvant with bupivacaine. Objective: Our study was aimed to compare the clinical efficiency of nalbuphine and fentanyl as adjuvant to hyperbaric bupivacaine for anal and perianal surgery. Methods: In this prospective randomized clinical trial patients were included from January 2007 to June 2008 at Khulna Medical College & some private clinics in Khulna. Patients were ASA (American Society of Anaesthesiology) status I & II of both gender aged 18-70 years and was randomized into two groups. Each group received either nalbuphine, (Group I) or fentanyl (Group-II) with bupivacaine. After intrathecal use every patient was examined for sensory and motor block, drug related side effects like hypotension pruritus, nausea, vomiting respiratory depression for three hours and were recorded. Results: Among two hundred study patients mean age was 49.5 and 5.2 in respective group I & II. Male female ratio was 16:14 in group I, whereas in group II it was 65:35. Mean duration of surgery was 46 and 43 minutes respectively in group I & II. Onset and cephalic extension of block was almost same in both groups. Time to recovery of sensory and motor block were significantly prolonged in Group 1. Duration of analgesia was also extended in group I. No significant drug related side effects were observed in either group. Conclusion: Nalbuphine as adjuvant to bupivacaine was clinically more efficient than fentanyl for post--operative analgesia and duration of sensory and motor block in SAB (Sub Aracnoid Block) for anal and perianal surgery. Bang Med J Khulna 2020: 53 : 27-30

EFFICACY OF 1% TOPICAL VORICONAZOLE IN THE TREATMENT OF MYCOTIC CORNEAL ULCER : A CLINICAL STUDY

2021 ◽  
pp. 66-68
Author(s):  
Urvashi Singh ◽  
Gopal prasad singh ◽  
Alka Jha
Keyword(s):  
Complete Resolution ◽  
Corneal Ulcer ◽  
Tertiary Care Hospital ◽  
Topical Therapy ◽  
Tertiary Care ◽  
Care Hospital ◽  
Single Centre ◽  
Medical College ◽  
Department Of Ophthalmology ◽  
One Year

Aim:To evaluate the efcacy of topical Voriconazole in the treatment of fungal corneal ulcer. Materials and methods: It was a single centre prospective tertiary care hospital based study conducted in the Upgraded Department of Ophthalmology at DARBHANGA MEDICAL COLLEGE AND HOSPITAL, Laheriasarai. It included 25 corneal ulcer patients of all demographic and socioeconomic status attending outdoor and/or indoor of Department of Ophthalmology, from April 2019 to April 2020, for a period of one year. Result: Majority of the patients were females.The decrease in ulcer size and improvement in visual acuity post treatment with topical Voriconazole was found to be statistically signicant. Conclusion: Topical therapy with 1% Voriconazole (w/v) served to be an economical mode of treating fungal corneal ulcer. It helped in the early and complete resolution of the ulcer with no adverse effects.

Efficacy of Supratarsal Triamcinolone Injection versus Dexamethasone in Recalcitrant Vernal Keratoconjunctivitis

2021 ◽  
Vol 15 (10) ◽  
pp. 2590-2592
Author(s):  
Muhammad Amin ◽  
Abdul Bari Kakar ◽  
Chakar Tajwidi ◽  
Nesr Farooq ◽  
Hafiz Waqar Ahmad Ghauri ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Randomized Study ◽  
High Rate ◽  
Vernal Keratoconjunctivitis ◽  
Conjunctival Hyperemia ◽  
Medical College ◽  
Group I ◽  
Department Of Ophthalmology ◽  
Triamcinolone Injection ◽  
Group Ii

Aim: To determine the effectiveness of supratarsal triamcinolone injection versus dexamethasone in recalcitrant vernal keratoconjunctivitis. Study Design: Prospective/randomized study Place and Duration of Study: Department of Ophthalmology, Lorallai Medical College, Loralai from 1st October 2020 to 31st March 2021. Methods: Fifty patients (100 eyes) of both genders and age between 12-40 years were enrolled. Detailed demographics of enrolled cases age, sex and body mass index were recorded after taking informed written consent. All patients had recalcitrant vernal keratoconjunctivitis. Patients were equally divided into 2-groups. Group I had 25 patients and received 20mg of supratarsal triamcinolone injection in both eyes and group II with 25 patients received 2mg of dexamethasone in their eyes. Postoperative effectiveness, complications and recurrence of disease was observed and compared among both groups. Results: There were 15 (60%) males and 10 (40%) females in group I with mean age 18.14±6.34 years while in group II, 15 (60%) males and 10 (40%) females with mean age was 17.68±4.54 years. Palprebral vernal keratoconjunctivitis was found in 36 eyes (10 patients of group I and 8 patients of group II) and Mixed vernal keratoconjunctivitis in 64 eyes (15 patients of group I and 17 patients of group II). Symptoms were itching,photophobia, lacrimation and pain. Conjunctival hyperemia, giant papillae and limbal infiltrate were the most common signs observed. Post operatively effectiveness among group I and II was (100% vs 92%) without any complication. Recurrence rate of vernal keratoconjunctivitis in group I was lower 4% as compared to group II 10%. Conclusion: The use of supratarsal triamcinolone injection in patients of recalcitrant vernal keratoconjunctivitis was effective and safest method as compared to dexamethasone in terms of less recurrence and high rate of efficacy. Keywords: Supratarsal triamcinolone, Dexamethasone, Vernal keratoconjunctivitis, Effectiveness, Recurrence

Acute poisoning in southern part of Bangladesh – The case load is decreasing

1970 ◽  
Vol 37 (2) ◽  
pp. 61-65 ◽  
Author(s):  
FR Chowdhury ◽  
AU Rahman ◽  
FR Mohammed ◽  
A Chowdhury ◽  
HAMN Ahasan ◽  
...  
Keyword(s):  
Copper Sulphate ◽  
Tertiary Hospital ◽  
Acute Poisoning ◽  
Age Group ◽  
Toxic Agent ◽  
Female Ratio ◽  
Medical College ◽  
Group I ◽  
Unknown Substance ◽  
Puffer Fish

This retrospective study was carried out in the Medicine Department of Khulna Medical College, the biggest tertiary hospital in the southern part of Bangladesh to observe the trends of poisoning in southern part of Bangladesh over four years including age and sex variation, mode of poisoning, type of poison used and outcome of poisoning. The hospital medical records of all patients, aged 10 years and above with history of acute poisoning from January, 2003 to December, 2006 were enrolled. Patients were categorized into four age group including Group (Gr.) I, Gr. II, Gr. III & Gr. IV having age range of 10-20, 21-30, 31-40 & >40 respectively. Underlying causes of poisoning were also observed totally and individually in different mode with male, female ratio and the percentage. Death cases according to mode of poisoning with demographic alignment were also observed. Statistical analysis were done using epi-info version 3.5.1 and measures were presented as proportion and percentage. Among 1903 cases, 1012 (53.1%) were male and 891 (46.8%) female with a ratio of 1.4: 1. The year wise total number of cases were progressively decreased from 627 (2003) to 353 (2006). Most commonly found toxic agent was Organo-Phosphate compound (526; 27.64%) with a very little sexual variation & this trend remained same in all study years. Poisoning with unknown substance was the second leading cause (16.03%) followed by Copper-sulphate (14.03%), Sedative (13.35%), Snakebite (12.93%) etc. Incidence of unknown poisoning, sedatives, snake-bite and corrosives were found to be gradually decreased over the study years. Male were found mostly affected in majority type of poisoning except Copper-sulphate, kerosene, puffer fish, paracetamol and other drugs category. Age group II (710; 37.3%) was the most vulnerable group with male (57.89%) preponderance followed by group I (643; 33.7%), III (329; 17.2%) and IV (221; 11.6%) respectively. Highest 1308 (68.7%) cases were suicidal in mode followed by 304 (15.9%) accidental and 291 (15.2%) homicidal. Out of 1903, 140 (7.3%) patients died. Death rate was highest in OPC poisoning (52.1%) followed by unknown substance (13.5%), snakebite and copper-sulphate (11.4%) etc. In an agro-based country like Bangladesh, it’s very difficult to reduce the poisoning cases and mortality. Prospectively designed multi-centered studies are needed to reflect the epidemiological properties of poisonings throughout Bangladesh, and would be very valuable for the determination of preventive measures. DOI: http://dx.doi.org/10.3329/bmrcb.v37i2.8436 BMRCB 2011; 37(2): 61-65

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