In Hospital outcome of Prediction of Peripheral Arterial disease In Diabetic Tobacco User Patients

2018 ◽  
Vol 9 (2) ◽  
pp. 102-109
Author(s):  
Syed Dawood Md Taimur ◽  
Sahela Nasrin ◽  
M Maksumul Haq ◽  
Hemanta I Gomes ◽  
Farzana Islam
Keyword(s):  
Clinical Practice ◽  
Peripheral Artery Disease ◽  
Arterial Disease ◽  
User Group ◽  
Peripheral Artery ◽  
Tobacco User ◽  
Group I ◽  
Group Ii ◽  
Artery Disease ◽  
Peripheral Arterial

Background: Peripheral artery disease (PAD) is a distinct atherosclerotic disorder marked by stenosis of the arteries common in tobacco users. Here we investigate prediction of unknown peripheral arterial disease (PAD) amongst patients with diabetic tobacco user and diabetic without tobacco user.Methodology: This prospective observational study was conducted in the Department of Cardiology, Ibrahim Cardiac Hospital and Research Institute, Dhaka, Bangladesh. A total of 60 patients were enrolled in this study who were presented with chest pain associated with lower limb claudication. They were diabetic population, constituted tobacco user in group-I and without tobacco user in group-II.Results: Hypertension was the leading risk factor in both groups (76.7% vs. 80%). 80% of patients of group I and 46.7% of patients of group II had mild form of ABI value. 3.3% of patient of group II had severe form of ABI value. There was no statistical significant difference between two group of patients (p=0.053). 93.3% patients of group I and 96.7% patients of group II had coronary artery disease. Twenty three patients of tobacco user group (n=30) had peripheral artery disease, whereas ten patients of without tobacco user group (n=30) had peripheral artery disease which was statistically significant (p=0.003). Three quarters (76.7%) of group I developed PVD as compared to 33.3% of group II. The risk of developing PVD in diabetic smokers was observed to be more than 6 fold (95% CI: 2.109-20.479) higher than that in non tobacco user were diabetics. 16.7% patients of group I atherosclerosis in femoral artery and the value is 10% in case of group-II, which is statistically in significant(p=0.433).Conclusion: The awareness and implementation of ABI in general clinical practice is poor. A simple, inexpensive test like ABI can improve the diagnosis of PAD in clinical practice and thus help in preventing CAD and consequent death by a range of medical therapies.Anwer Khan Modern Medical College Journal Vol. 9, No. 2: Jul 2018, P 102-109

scholarly journals Association between Peripheral Arterial Disease and Coronary Artery Disease among Tobacco User Diabetic Patients

2017 ◽  
Vol 32 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Syed Dawood Md Taimur ◽  
M Maksumul Haq ◽  
MA Rashid ◽  
SM Keramat Ali ◽  
Md Shahjahan ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
Diabetic Patients ◽  
Peripheral Artery ◽  
Tobacco User ◽  
Group I ◽  
Artery Disease ◽  
Peripheral Arterial

Background: Peripheral arterial disease (PAD) is a marker of increased risk for cardiovascular events and of poorer prognosis in patients with coronary artery disease (CAD). The prevalence of unknown PAD amongst patients with ACS varies between studies according to the mode of diagnosis.Aims: To evaluate the prevalence of peripheral arterial disease (PAD) in diabetic ACS patients with or without tobacco user by using ankle brachial index (ABI).We also assess the probable predictors of PAD among these patients.Methodology: This prospective observational study was conducted in the Department of Cardiology, Ibrahim Cardiac Hospital and Research Institute, Dhaka, Bangladesh starting from 1st January 2016 to 30th April 2016 over a period of four months. A total of 60 patients were studied. They were grouped on the basis of their smoking habit. Diabetic patients with ACS and tobacco user (smoke and smoke less) in group I and without tobacco user in group II.Results: The mean age of the studied patients was 56.63 ± 8.95 years, range from 25-90 years. 73.30% was male and 26.70% was female. Twenty three patients of tobacco user in group-I (n=30) had peripheral artery disease and ten patients of group-II (n=30) had peripheral artery disease. It was statistically significant (p=0.003).Conclusion: There is correlation between peripheral arterial disease and coronary artery disease. Diagnosis and supervision of patients with PAD is important for preventing the local progression of the disease and effective secondary prevention of future coronary and cerebrovascular events.Bangladesh Heart Journal 2017; 32(1) : 3-9

Dobutamine stress cardiovascular magnetic resonance imaging in patients with peripheral artery disease

2011 ◽  
Vol 152 (8) ◽  
pp. 285-291 ◽  
Author(s):  
Róbert Kirschner ◽  
Zsolt Pécsvárady ◽  
J. Róbert Bedros ◽  
Levente Tóth ◽  
Krisztián Kiss ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Peripheral Artery Disease ◽  
Wall Motion ◽  
Arterial Disease ◽  
Dobutamine Stress ◽  
Cardiovascular Mri ◽  
Peripheral Artery ◽  
Target Heart Rate ◽  
Artery Disease ◽  
Peripheral Arterial

Patients with peripheral arterial disease often have coronary heart disease, as well. However, their assessment with classical noninvasive cardiology methods is often non-diagnostic or limited. The aim of this study was to analyze the feasibility and the risks of dobutamine stress cardiovascular MRI for cardiac evaluation of patients with peripheral arterial disease. 21 patients with peripheral artery disease (mean±SD age 64.3±7.7 years) were studied prospectively with dobutamine stress cardiovascular MRI. The protocol was completed by all of 21 patients. The target heart rate was attained in 95.2% of the studies. No serious adverse event occurred. The image quality scores (1-4) for all ventricular wall segments were high (median, interquartile range) (4 [4-4]). Five patients (23.8%) have inducible wall motion abnormality. Interobserver agreement was almost perfect for wall motion scores (κ = 0.87, p<0.0001). Dobutamine stress cardiovascular MRI is feasible with low risk for the cardiological assessment of patients with peripheral arterial disease. Orv. Hetil., 2011, 152, 285–291.

scholarly journals Peripheral arterial disease – an underappreciated clinical problem

Medicina ◽  
2008 ◽  
Vol 44 (4) ◽  
pp. 328
Author(s):  
Edita Mašanauskienė ◽  
Albinas Naudžiūnas
Keyword(s):  
Peripheral Arterial Disease ◽  
Peripheral Artery Disease ◽  
Ankle Brachial Index ◽  
Clinical Problem ◽  
Arterial Disease ◽  
Cardiovascular Complications ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Doctor's Office ◽  
Peripheral Arterial

Peripheral artery disease is a common vascular disorder. In contrast to coronary and cerebral artery disease, peripheral arterial disease remains an underappreciated condition that despite being serious and extremely prevalent is rarely diagnosed and even less frequently treated. Early diagnosis of peripheral artery disease and individual assessment of risk factors are important in preventing further cardiovascular complications. The ankle-brachial index is a simple, reliable tool for diagnosing peripheral artery disease. Many studies underscore the importance of using the ankle-brachial index to identify persons with peripheral artery disease, since peripheral artery disease is frequently undiagnosed or asymptomatic. Measurement of the ankle-brachial index is simple enough to be performed in any doctor’s office, and it is one of the most reliable indices of peripheral artery disease.

scholarly journals Gender Differences in the Medical Treatment of Peripheral Artery Disease

2021 ◽  
Vol 10 (13) ◽  
pp. 2855
Author(s):  
Damien Lanéelle ◽  
Gabriella Sauvet ◽  
Jérôme Guillaumat ◽  
Jean Eudes Trihan ◽  
Guillaume Mahé
Keyword(s):  
Peripheral Arterial Disease ◽  
Medical Treatment ◽  
Peripheral Artery Disease ◽  
Severe Disease ◽  
Arterial Disease ◽  
Peripheral Artery ◽  
Primary Health ◽  
Cardiovascular Morbidity And Mortality ◽  
Artery Disease ◽  
Peripheral Arterial

Background/Objectives: Peripheral arterial disease is a frequent and severe disease with high cardiovascular morbidity and mortality. However, female patients appear to be undertreated. Objectives: The primary goal was to compare the prescription of optimal medical treatment (OMT) of peripheral arterial disease between women and men in primary health care. Material and methods: An observational retrospective study was based on the data collected from general practitioners (GP) office in Brittany. Results: The study included 100 patients, aged 71 ± 10 years old, with 24% of women. Compared to men, women received the OMT less frequently (29.2% vs. 53.9%, p = 0.038), especially after 75 years old. Antiplatelet therapy was largely prescribed (100%), statins less frequently (70.8% women vs. 85.5% men), and prescription of renin-angiotensin-aldosterone system inhibitors was still not optimal in the two genders (41.7% women vs. 61.9% men). Active smoking is important for both women and men (33% and 30% respectively). Conclusion: Optimal medical treatment of peripheral artery disease is insufficiently prescribed, especially in women in this region of France.

scholarly journals Diagnosis of Peripheral Artery Disease using Cnn Classifier

2020 ◽  
Vol 8 (5) ◽  
pp. 5421-5425
Keyword(s):  
Peripheral Arterial Disease ◽  
Peripheral Artery Disease ◽  
Early Stage ◽  
Arterial Disease ◽  
Input Image ◽  
The Body ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Peripheral Arterial ◽  
Specific Symptoms

Peripheral Arterial Disease is common to all elderly peoples, which reduces the blood flow to the limbs. Due to PAD, the affected person unable to walk and gives pain while they try to walk. This PAD does not have any specific symptoms to affected persons in the earlier stage. This paper presents a solution to find the disease in which stage the person was affected. The Peripheral arterial disease is evaluated using convolution neural network classifier to identify in early stage to take treatments. The affected persons image (particular part of the body. Eg. Leg) is compared with the dataset. The dataset contains the collection of images that contains both normal and Peripheral arterial disease affected images. The CNN classifier compares with the dataset and shows that the given input image is in normal stage or it is affected by the Peripheral Artery disease. The accuracy level is high. This methodology helps to find the disease in earlier stage

scholarly journals Association Between AST to ALT Ratio and Peripheral Artery Disease in Chinese Hypertensive Population: A Cross-Sectional Study

2020 ◽  
Author(s):  
Hui Liu ◽  
Xiaoyuan Zha ◽  
Congcong Ding ◽  
Lihua Hu ◽  
Minghui Li ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Peripheral Artery Disease ◽  
Reference Group ◽  
Arterial Disease ◽  
Multivariate Logistic Regression Model ◽  
Peripheral Artery ◽  
Cross Sectional ◽  
Increased Risk ◽  
Artery Disease ◽  
Peripheral Arterial

Abstract Background: Previous studies had shown the role of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AST/ALT) in cardiovascular disease . Peripheral artery disease(PAD) is an important risk factor for cardiovascular death. However, there are fewer investigations of the correlations between the AST/ALT ratio and Peripheral artery disease (PAD). Methods: We analyzed data of 10,900 hypertensive patients from the Chinese Hypertension Registry Study. Using a multivariate logistic regression model, we examined the association between AST / ALT and peripheral arterial disease (PAD),which was defined as ABI≤ 0.9 in either leg.Results：A total of 350 patients had peripheral arterial disease and the prevalence of PAD was 3.21%. After adjusting for potential confounders, AST / ALT ratio was independently and positively associated with risk of PAD (OR: 1.31, 95% CI: 1.13 to 1.59), and a statistically significant increased risk of PAD for the third AST / ALT ratio tertile (T3) compared to the first tertile (T1) (OR:1.49, 95% CI: 1.09 to 2.04, P-trend= 0.005) was found. Moreover, when we combined T1-T2 into one group and used it as a reference group, the risk of PAD increased with the increase of AST/ALT and the risk ratio was 1.52 (95% CI :1.20 to 1.95). Conclusion: A higher AST/ALT ratio (≥1.65) was associated with PAD risk in Chinese adults with hypertension. Our results suggested that AST / ALT maybe help us highlight patients who was at high risk of vascular endpoints.Trial registration: CHICTR, CHiCTR1800017274. Registered 20 July 2018.

scholarly journals Ankle-Brachial Index predicts Coronary Artery Disease associated with Peripheral Arterial Disease

1970 ◽  
Vol 6 (1) ◽  
pp. 23-25
Author(s):  
SM Ahsan Habib ◽  
M Nazrul Islam ◽  
Kamal Pasha ◽  
Saleh Ahmed Nurul Alam ◽  
Khaled Mohsin ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Arterial Disease ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
Left Main ◽  
Group I ◽  
Group Ii ◽  
Artery Disease ◽  
Peripheral Arterial

Most common cause of Peripheral Arterial Disease (PAD) is atherosclerosis. Atherosclerosis is a generalized disease, also involving coronary and carotid arteries. Often atherosclerotic coronary artery disease (CAD) is associated with PAD. This prospective observational study was conducted in the National Institute of Cardiovascular Diseases, Dhaka, Bangladesh, during July 2004 to June 2005. Total 58 patients with PAD were included in the study. Patients were classified as group I having normal coronary artery, group II insignificant CAD (Left main <50% stenosis, others <70% stenosis) and group III, significant CAD (Left main ≥50% stenosis, others ≥70% stenosis). Ankle-brachial index was significantly low (0.75±0.25 Vs 0.37±0.40) in the patients with coronary artery disease (Group II and III) compare to non-CAD (P =0.001).This study suggests that ankle-brachial index (ABI) have significant relation with the presence of CAD. Key words: Ankle-Brachial Index; peripheral arterial disease DOI: 10.3329/uhj.v6i1.7186University Heart Journal Vol.6(1) 2010 pp.23-25

scholarly journals Peripheral Vascular Intervention: A Review

2019 ◽  
Vol 34 (1) ◽  
pp. 58-67
Author(s):  
Mohsin Ahmed ◽  
Abul Hasan Muhammed Bashar ◽  
Abdullah Al Gaddafi
Keyword(s):  
Peripheral Arterial Disease ◽  
Peripheral Artery Disease ◽  
Exercise Program ◽  
Arterial Disease ◽  
Peripheral Artery ◽  
Vascular Intervention ◽  
Long Term Outcome ◽  
Supervised Exercise ◽  
Artery Disease ◽  
Peripheral Arterial

The prevalence of peripheral artery disease (PAD) continues to increase worldwide. It is important to identify patients with PAD because of the increased risk of myocardial infarction, stroke, and cardiovascular death and impaired quality of life because of a profound limitation in exercise performance.Lower extremity PAD affects approximately 10% of population, with 30% to 40% of these patients presenting with claudication symptoms. Peripheral arterial disease is common, but the diagnosis frequently is overlooked because of subtle physical findings and lack of classic symptoms. Screening based on the ankle brachial index using doppler ultrasonography may be more useful than physical examination alone. Noninvasive modalities to locate lesions include duplex scanning, computed tomography angiogram, magnetic resonance angiography and invasive modalities peripheral angiogram is the gold standard. Major risk factors for peripheral arterial disease are cigarette smoking, diabetes mellitus, older age (older than 40 years), hypertension, hyperlipidemia, and hyperhomocystinemia. Intermittent claudication may be improved by risk-factor modification, exercise, and pharmacologic therapy. Based on available evidence, a supervised exercise program is the most effective treatment. Effective drug therapies for peripheral arterial disease include aspirin (with or without dipyridamole), clopidogrel, cilostazol, and pentoxifylline. By contrast, critical limb ischemia (CLI) is considered the most severe pattern of peripheral artery disease. It is defined by the presence of chronic ischemic rest pain, ulceration or gangrene attributable to the occlusion of peripheral arterial vessels. It is associated with a high risk of major amputation, cardiovascular events and death. The management of CLI should include an exercise program, guideline-based medical therapy to lower the cardiovascular risk. Most of the cases, revascularization is indicated to save limbs; an “endovascular first” approach and lastly surgical approach, if all measures were failed. The choice of the intervention is dependent on the anatomy of the stenotic or occlusive lesion; percutaneous interventions are appropriate when the lesion is focal and short but longer lesions must be treated with surgical revascularisation to achieve acceptable long-term outcome. Bangladesh Heart Journal 2019; 34(1) : 58-67

Anti-platelet and anti-coagulant therapy in peripheral arterial disease prior to surgical intervention

Vascular ◽  
2018 ◽  
Vol 27 (3) ◽  
pp. 299-311 ◽  
Author(s):  
Amer Harky ◽  
Perry Maskell ◽  
Mika Burgess
Keyword(s):  
Peripheral Artery Disease ◽  
Arterial Disease ◽  
Peripheral Artery ◽  
Randomized Controlled ◽  
Major Cardiovascular Events ◽  
Co Morbidity ◽  
Artery Disease ◽  
Peripheral Arterial ◽  
Meta Analyses

Objective Peripheral artery disease is a major clinical co-morbidity that can significantly affect quality of life, especially in the presence of diabetes mellitus and older age. The focus of this literature review is on medical management, through anti-platelet and anti-coagulation, of peripheral artery disease prior to undergoing surgical or endovascular management. Method Extensive electronic literature search performed in four major databases (PubMed, SCOPUD, Embase and Ovid) to identify the published randomized and non-randomized studies that compared and discussed the management of peripheral artery disease with different anti-thrombotic agents. Results A total of 17 studies were identified to meet the inclusion criteria of this review. Among them, 4 were systematic review and meta-analyses, 1 was observational study and 12 were randomized controlled trials. The reported outcomes in each study are summarized and reported separately within this review. Conclusion Peripheral artery disease is a complex and multifactorial clinical condition. The use of dual anti-platelets, such as aspirin and clopidogrel, are the key in preventing major cardiovascular events as well as stroke and death. Utilization of anti-coagulation such as direct oral anti-coagulants’ as additional parameters for the prevention of disease progression, is paramount. Eventually, the choice of either dual-antiplatelet therapy or combined anti-coagulation with anti-platelets should be carefully considered, particularly following the most recent published debatable studies.

scholarly journals Comprehensive Analysis of Invasive and Noninvasive Investigation Methods in Peripheral Artery Disease

2019 ◽  
Vol 24 (4) ◽  
pp. 37-39
Author(s):  
Oana Stoia ◽  
Ioan Manițiu ◽  
Ioan Bitea ◽  
Mihaela Racheriu ◽  
Gabriela Eminovici
Keyword(s):  
Digital Subtraction Angiography ◽  
Peripheral Artery Disease ◽  
Arterial Disease ◽  
Lower Limbs ◽  
Digital Subtraction ◽  
Peripheral Artery ◽  
Investigation Methods ◽  
Slow Progression ◽  
Artery Disease ◽  
Peripheral Arterial

Abstract Peripheral artery disease of the lower limbs is, in fact, an arterial pathology, by which the blood flow is reduced, due to the obstruction caused by the deposit of atheroma plaques.(1) This deposition occurs slowly, which leads to a slow progression of the disease, and thus, at the onset of symptomatology. The objective of the study was to make a comparison between the invasive and noninvasive paraclinical investigations performed in patients with peripheral arterial disease of the lower limbs in the E.C.C.H. Sibiu. In conclusion, between the two investigations (computed tomography angiography and digital subtraction angiography) there are no noticeable differences in the terminal aorta and iliac arteries, but in reducing the arteries calibre, the use of digital subtraction angiography is preferred, according to our study, although it is more invasive and exposed to complications.

Sign in / Sign up

Export Citation Format

Share Document