scholarly journals Study of anemia among hemophilia patients

2018 ◽  
Vol 17 (4) ◽  
pp. 573-575
Author(s):  
Rafiqul Haque ◽  
Dannish Arefin Biswas ◽  
Shafiul Alam Quraishi

Background: Almost all hemophilia patients are treated with fresh frozen plasma and other alternatives regardless of anemic status, so it is important to identify the patients who are chronically anemic and thereby those cases to be treated accordingly. As no previous work and research regarding study of anemia among hemophilia patients were done in our country and abroad as far as I know, so data regarding this study from online source could not be compiled here.Objective: The objective of the study was to evaluate the degree of anemic status among hemophilia patients who were receiving FFP for long time.Materials and Method: It was a prospective type of observational study. The study was carried out in the Department of Transfusion Medicine, BSMMU, Dhaka, Bangladesh. This study was conducted from July 2011 to June 2012 for a period of one (1) year. 60 patients with hemophilia were selected from patients attending at day care unit of Transfusion Medicine dept. of BSMMU.Results: Among 60 patients, according to degree of anemia majority cases are moderately anemic which were 35(58.33%) cases followed by mildly anemic which were 15(25.00%) cases, Severely anemic were 2(3.33%).Non anemic cases were 10(16.67%).Bangladesh Journal of Medical Science Vol.17(4) 2018 p.573-575

2019 ◽  
Vol 19 (1) ◽  
pp. 148-151
Author(s):  
Md Rafiqul Haque ◽  
Dannish Arefin Biswas ◽  
Razia Akhter ◽  
Farhana Jaya Chowdhury ◽  
Zia Uddin Ahmed

Background: Almost all hemophilia patients are treated with fresh frozen plasma and other alternatives. As they are on multiple transfusion of FFP, majority of the patient experience adverse reaction to FFP transfusion. There are various types of adverse events occur that are documented in national and international data. My research activity targeted to explore commonly encountered adverse events among Bangladeshi population. This helps the physician to plan a management protocol. Objective: The objective of the study was to evaluate the adverse events of FFP transfusion who are receiving FFP for long time. Materials and Method: It was a prospective type of observational study. The study was carried out in the Department of Transfusion Medicine, BSMMU, Dhaka, Bangladesh. This study was conducted from July 2011 to June 2012 for a period of one (1) year. 60 patients with hemophilia were selected from patients attending at day care unit of Transfusion Medicine dept. of BSMMU. Results: Among 60 patients, 53.33% patients develop itching 36.67% patients developed urticaria, 6.67% patients develops fever and rigor and 3.33 patients developed nausea. Conclusion: In this study it was found that majority of the patients developed itching following transfusion of FFP. Adverese events like urticaria, fever and nausea ranked as 2nd, 3rd and 4th position respectively. Bangladesh Journal of Medical Science Vol.19(1) 2020 p.148-151


2014 ◽  
Vol 58 (1) ◽  
pp. 29-30
Author(s):  
Pierre Pasquier ◽  
Etienne Gayat ◽  
Thibaut Rackelboom ◽  
Julien La Rosa ◽  
Abeer Tashkandi ◽  
...  

2017 ◽  
Vol 119 (3) ◽  
pp. 422-434 ◽  
Author(s):  
P.W. Collins ◽  
R. Cannings-John ◽  
D. Bruynseels ◽  
S. Mallaiah ◽  
J. Dick ◽  
...  

2014 ◽  
Vol 34 (1) ◽  
pp. 33
Author(s):  
P. Pasquier ◽  
E. Gayat ◽  
T. Rackelboom ◽  
J. La Rosa ◽  
A. Tashkandi ◽  
...  

2013 ◽  
Vol 116 (1) ◽  
pp. 155-161 ◽  
Author(s):  
Pierre Pasquier ◽  
Etienne Gayat ◽  
Thibaut Rackelboom ◽  
Julien La Rosa ◽  
Abeer Tashkandi ◽  
...  

1970 ◽  
Vol 18 (2) ◽  
pp. 132-135
Author(s):  
SD Adnan ◽  
J Biswas ◽  
HA Begum ◽  
MM Hoque ◽  
FS Chowdhury

This cross sectional study was carried out at Bangabandhu Sheikh Mujib Medical University, Dhaka during the period of November 2008 to April 2009 on patients who received fresh frozen plasma. Relevant information of those patients was noted from the records kept at the Department of Transfusion Medicine. The collected data was statistically analyzed.In this study it was observed that 939 units of FFP were required in BSMMU during study period. 289 patients required these units of FFP. The age of the patients that required FFP ranged from 1 day to 75 years. Among them highest 99 (34.25%) were in the age group1 day to. 10 years. There were178 (61.59%) males and 111 (38.41%) females. Out of 289 patients 111 (38.41%) was B+ve, 86 (29.76%) was O+ve, 66 (22.84%) was A+ve and 26 (08.99%) was AB+ve. According to Rh typing maximum unit 930 (99.04) units were Rh D +ve, 9 units (00.96%) were Rh D-ve. Highest number of FFP Unit 329 (35.04%) was used in day care center in transfusion medicine department. Followed by Gastro-enterology 188 (20.02%), Burn & Plastic surgery 140(14.91%), Paediatrics & allied 106 (11.29%), Rest 176 units by other departments.According to clinical indication highest number of FFP Unit 271 (28.86%) was used for Hemophilia A, followed by CLD 210 (22.36%), Burn140 (14.91%). Distribution of the units of FFP according to rational use it was found that a large number of unit 386 (41%) use was not clinically justified. Study shows 60 (20.77%) patients was not supplied with correct documentation. According to requirement Transfusion Medicine alone uses 35%, other dept of university uses 46%, 19% of unit is supplied to other medical centers. Key words: Fresh frozen plasma; Transfusion; Clinical audit. DOI: 10.3329/jdmc.v18i2.6273 J Dhaka Med Coll. 2009; 18(2) : 132-135


1999 ◽  
Vol 123 (6) ◽  
pp. 492-495 ◽  
Author(s):  
Barbara Alving ◽  
Kirsten Alcorn

Abstract As transfusion medicine becomes more complex, cooperative strategies are gaining increasing importance in relaying information to the treating physician and in incorporating the treating physician into the education and quality control processes. The broad domain of transfusion medicine is illustrated by the variety of disciplines involved in defining the use of products such as fresh frozen plasma and the newly released solvent-detergent–treated plasma, fibrin glue and highly purified fibrin sealant, and leukoreduced and irradiated blood products. Cooperative efforts among physicians and other personnel of multiple disciplines are essential to ensure appropriate use and continuous evaluation of blood products.


Author(s):  
S. Nagulan ◽  
A. Hariharan ◽  
I. Sureshkumar ◽  
S. Chitra

Aim: To study the efficacy of Fresh Frozen Plasma (FFP) transfusion practice in patients with coagulation abnormalities varies in clinical practice. Study Design: A retrospective study. Place and Duration of Study: This study was conducted in Department of Transfusion Medicine, SMCH, Chennai, between the period of 2019-2020. Methodology: The medical records of each patient receiving FFP transfusions that occurred in patients with coagulation abnormalities were reviewed and the data were collected based on pre-and post transfusion PT (>12 sec), APTT (>70sec) and INR (>1.5) and then analysed statistically. Patients with normal coagulation parameters were excluded from study. Results: A total of 1259 units of fresh frozen plasma were transfused to 315 patients between the year 2019-2020. Of the 1259 units transfused 1133 units where transfused to 283 patients with coagulation abnormalities. Apparently 32 patients were excluded from the study as they had normal coagulation profile. Among 251 patients, 37 patients PT were greater than 12 seconds before FFP transfusion out of which the PT was corrected for 14 patients (37.8%) after FFP transfusion. In 228 patients APTT was greater than 70 seconds before FFP transfusion, out of which APTT was corrected in 18 patients (8%) after transfusion. INR values for all 251 patients were greater than1.5 before FFP transfusion, out of which INR was corrected in 84 patients (29%) after transfusion. Conclusion: We conclude that FFP transfusions in patients with coagulation abnormalities maycorrects the defect only in less percentage of patient population, as in our study it corrects only an average of 31% of patient population.


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