scholarly journals The challenge in diagnosing Crohn’s disease in TB endemic region – A case report with review of literature

2018 ◽  
Vol 17 (4) ◽  
pp. 688-690
Author(s):  
S Suban Mohammed Gouse ◽  
Hemalatha Ganapathy ◽  
Bhuvanamha Devi ◽  
G Bheema Rao ◽  
BO Parijatham

The challenge in diagnosing the regional ileitis existed since 1932 when Crohn, Ginzberg and Oppenheimer first reported their case1. Many Indian researchers accepted that during last decade there was considerable increase in the incidence of Crohn’s disease (CD) in India which poses great challenge in diagnosing it, due to high prevalence of tuberculosis2. In this perspective we report a case which made a stimulus to review the literature. The purpose of this manuscript is 1. To document the occurrence of an additional case of CD in India, 2. To report that CD can rarely present as post operative enterocutaneous fistula, 3. To discuss the criteria in diagnosing the CD in Tuberculosis (TB) endemic area.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.688-690

Chirurgia ◽  
2017 ◽  
Vol 30 (4) ◽  
Author(s):  
Donatella Pisaniello ◽  
Nicola Della Valle ◽  
Nicola Crucinio ◽  
Anna Carretta ◽  
Giovanni Di Gioia ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Pamathy Gnanaselvam ◽  
Dhanushka N. Weerakoon ◽  
W. A. M. Wijayasuriya ◽  
Vishva Samidi Mohottala ◽  
B. M. E. S. Sinhakumara ◽  
...  

The isolated appendiceal Crohn’s disease without preceding bowel symptoms is a rare phenomenon, especially in older patients. In this case report, we present a 60-year-old female with isolated appendiceal Crohn’s disease presenting with acute appendicitis. She presented with classical features of appendicitis with elevated inflammatory markers. She underwent an appendectomy which showed an excessively swollen, oedematous, and reddish appendix with swelling extending to the base of the caecum. Histological evaluation was suggestive of Crohn’s disease, and subsequent colonoscopy was unremarkable. Following appendectomy, she was asymptomatic without any recurrence of disease. The atypical morphological appearance of the appendix should raise suspicion of Crohn’s disease. This case highlights the importance of histopathological analysis of the specimen, especially in abnormal clinical findings. The prognosis of such patients seems to be good, and additional treatment is rarely needed.


1990 ◽  
Vol 4 (2) ◽  
pp. 59-63 ◽  
Author(s):  
Robert Prokopetz ◽  
J Barrie Ross ◽  
Peter Smith ◽  
Joseph J Sidorov

A patient presented with skin lesions at sites not contiguous with Crohn's disease of the bowel and with specific histological features of Crohn's disease occurring two weeks from the onset of bowel symptoms. Currently a number of nonspecific skin conditions such as erythema nodosum, pyoderma gangrenosum and erythema multiforme are accepted as being the most common skin manifestations of Crohn's disease. It is likely, however, that specific lesions of Crohn's disease in the skin have been underdiagnosed either because of lack of biopsy or misinterpretation of the histology. Twenty-three cases with specific Crohn's disease in the skin have been recorded in the past 25 years, since the condition has been recognized. Sarcoidosis has been a common misdiagnosis. The literature relating to multicentric Crohn's disease is reviewed and attention drawn to its protean and masquerading features. An argument is made for the use of the term 'multicentric' rather than 'metastatic' in relation to cutaneous Crohn's disease.


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