scholarly journals Antioxidant activities of dithiol alpha-lipoic acid

1970 ◽  
Vol 8 (3) ◽  
pp. 46-51 ◽  
Author(s):  
Mohammad Toowhidul Islam

Alpha-lipoic acid, a dithiol compound derived from octanoic acid, which acts as a coenzyme for several redox reactions in almost all the tissue of the body. It retains its protective functions in both oxidized and reduced forms. Alpha-lipoic acid reduces oxidative stress by redox generation of other antioxidants such as vitamin C, E and increasing the intracellular glutathione. Exogenous alpha-lipoic acid has been shown to increase ATP production due to its role in the oxidation of pyruvate and alpha-ketoglutarate in the mitochondria. Alpha-lipoic acid administration has been shown to be effective in preventing pathology in various experimental models in which reactive oxygen species have been implicated. Key words: Antioxidant, free radical, alpha-lipoic acid   DOI: 10.3329/bjms.v8i3.3982 Bangladesh Journal of Medical Sciences Vol.8(3) 2009 p46-51

2021 ◽  
Author(s):  
triplebloodbalance not provided

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This can be advantageous in directing your circulatory strain and keeping your heart sound. It even keeps your blood cholesterol kept up with and forestalls cardiovascular issues. This may likewise permit you to have more prominent energy holds and keep you lively. It works with the progression of blood to the mind and the body and advances in general wellbeing. It can reinforce your resistant framework and make you more grounded from within. Normal Ingredients Incorporated to Make Triple Blood Balance Triple Blood Balance is an altogether natural enhancement that just includes the utilization of normal fixings. Here is a finished rundown of the normal fixings fused to make this enhancement A few Vitamins and Minerals: This enhancement includes a mix of supplements like Vitamin C, Vitamin E, Biotin, Magnesium, Manganese, Chromium, and Zinc too. L-Taurine: It is an astounding amino corrosive that aides in dealing with your glucose levels normally. It tends to be valuable in managing your cholesterol and helps in supporting your heart wellbeing. White Mulberry: These magnificent berries are wealthy in regular cancer prevention agents and in this manner detoxifies the body. It likewise animates your circulatory strain and holds your diabetic condition under tight restraints for more prominent in general wellbeing. Juniper: These are some different berries that are loaded with powerful antidiabetic, cancer prevention agents, and mitigating properties. It can even be useful in giving you every one of the fundamental supplements also. Triple Blood Balance fixings >>Click Here For Visit Official Website Order and Price Details << Unpleasant Melon: This is observed to be a notable solution for diabteic patients and along these lines deals with your glucose. It essentially behaves like insulin and thus gives viable outcomes significantly. 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The suggested utilization of this medical services supplement conveys different advantages. Interestingly, unnecessary admission might guide you to experience antagonistic incidental effects also. This is the reason ingesting too much of this regular enhancement should be limited and ought not be worked out. Any Possible Side Effects Involved with Triple Blood Balance It is framed of normally happening fixings and clear of any corrupted components too. These components might be counterfeit tones, fillers, or unforgiving additives and are risky to your body. They are known to build the degrees of poisons in your body and can create genuine side outcomes. They are even seen to unfavorably affect your general wellbeing. Finishing Thoughts Triple Blood Balance is a 100% regular enhancement that is successful at fostering your blood sythesis. This enhancement is planned by making the utilization of a few normal fixings, for example, Several Vitamins and Minerals, L-Taurine, White Mulberry, Juniper, Bitter Melon, Cayenne, Licorice, Yarrow, Cinnamon, Gymnema Sylvestre, Alpha-lipoic Acid, Guggul, and Banaba. These fixings are totally secure and clear from any incidental effects. These fixings cooperate and help in controlling your general blood measurements. It then, at that point, drives you to have a better body and broadened life range too. This is the main normal solution for supporting improved blood details and carrying on with a better life. NOTICE: We don't take any sort of liability regarding the items mentioned through different sellers or sources. Be that as it may, we are just responsible for the items requested through this specific site. This keeps you shielded from any potential tricks or web cheats also. 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2020 ◽  
Vol 13 (2) ◽  
pp. 157-162
Author(s):  
Boris Yushkov ◽  
Alexey Sarapultsev ◽  
German Sarapultsev

The search for preventive and treatment methods for adhesions of the abdominal cavity and adhesive disease is one of the most important tasks of pharmaceutical and medical sciences; and the solution is based on experimental research studies involving animals. However, the varietyof adhesion modeling techniques, as well as specific features of experimental animals imply considerable difficulties to such research. The aim of the review was to describe and systematize experimental models of the adhesive process in the peritoneum applicable to small laboratory animals. The authors identify major models of adhesion induction, emphasizing the species differences of small laboratory animals that could affect the interpretation and extrapolation of the data obtained. The authors have proven that since adhesion is a complete product of the body inflammatory response to tissue damage, the treatment of adhesions should be solely based on surgical techniques, while therapeutic approaches might only prevent, slow down or reduce the intensity of adhesion processes.


2003 ◽  
Vol 61 (3B) ◽  
pp. 738-745 ◽  
Author(s):  
Otoni Cardoso do Vale ◽  
Daniel Sá Roriz Fonteles ◽  
Francisco Romero Cabral ◽  
Manassés Claudino Fonteles

Oxidative stress causes metabolic and structural abnormalities during reperfusion. In an animal model of electrophysiological evaluation of cerebral ischemia-reperfusion, alpha-lipoic acid effect on the oxidative stress was studied by mean absolute amplitude of EEG spectra evaluation. The left carotideal infusion of 3.03 mM alpha-lipoic acid in Wistar rats after cerebral ischemia and reperfusion caused initial reduction and partial final recuperation of the various EEG spectral frequency mean absolute amplitudes (p<0.05). The left intracarotideal infusion of 6.06 mM alpha-lipoic acid significantly reverted the induced depression of mean absolute amplitude of theta and delta spectra. Nevertheless there was an increasing pattern of ischemia demonstrated by mean absolute amplitude depression of almost all EEG spectra with 60.6 mM alpha-lipoic acid infusion. These observations suggest that, depending on the administered concentration, alpha-lipoic acid may act in a dual way, protecting from ischemia at lower concentrations and worsening this process at higher doses.


2010 ◽  
Vol 34 (8) ◽  
pp. S14-S14
Author(s):  
Yi Yang ◽  
Wei‑Ping Wang ◽  
Yi‑Nan Liu ◽  
Ting Guo ◽  
Ping Chen ◽  
...  

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
A Uzunovic ◽  
S Hadzidedic ◽  
A Elezovic ◽  
S Pilipovic ◽  
A Sapcanin

2008 ◽  
Vol 46 (05) ◽  
Author(s):  
E Székely ◽  
K Szentmihályi ◽  
M Bor ◽  
Á Pusztai ◽  
T Kurucz ◽  
...  

Diabetes ◽  
1997 ◽  
Vol 46 (9) ◽  
pp. 1481-1490 ◽  
Author(s):  
A. Bierhaus ◽  
S. Chevion ◽  
M. Chevion ◽  
M. Hofmann ◽  
P. Quehenberger ◽  
...  

2017 ◽  
Vol 23 (1-2) ◽  
pp. 9-14
Author(s):  
E.H. Zaremba ◽  
◽  
O.V. Smalyukh ◽  
O.V. Zaremba-Fedchyshyn ◽  
O.V. Zaremba ◽  
...  

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