scholarly journals Spectrum of MDP Bone Scan in Paediatric Patients - Experience at NINMAS

2018 ◽  
Vol 19 (1) ◽  
pp. 28-31
Author(s):  
Pupree Mutsuddy ◽  
Shamim MF Begum ◽  
Nasreen Sultana ◽  
Rahima Parveen ◽  
Nabeel Fahmi Ali ◽  
...  
Keyword(s):  
Bone Scan ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Imaging Modality ◽  
Bone Tumour ◽  
Bone Diseases ◽  
Skeletal Survey ◽  
Clinical Indications ◽  
Paediatric Patients ◽  
Clinical Records

Objective: To assess the clinical indications and spectrum of MDP bone scan findings in paediatric patients referred to the National Institute of Nuclear Medicine and Allied Sciences (NINMAS).Materials and Methods: Paediatric patients, age ranged from 2-18 years referred to NINMAS from January 2014 to November 2015 for bone scintigraphy were included in this study. All patients had 99mTc MDP bone scan for various clinical indications. The spectrum of clinical indications and bone scan findings were recorded and analyzed.Results: Total 2323 bone scans with 99mTc MDP were done in NINMAS in the above mentioned period. Among them 91 (3.917%) cases were in paediatric age group. Of which 82 (90.11%) patients with known malignancy were referred for radionuclide skeletal survey. The most common clinical indications were osteosarcoma 30 (32.96%) cases and Ewing’s sarcoma 25 (27.47%) cases followed by five neuroblastoma (5.49%), four (4.39%) rhabdomyosarcoma, three (3.29%) Langerhans cell histocytosis and rest others. Bone scan was positive in 58 (63.7%) cases and normal in 33 (36.3%) cases. Out of 58 cases 38 had features of primary bony lesion, 10 cases had multiple metastases, four cases had primary bone tumour of Ewing’s sarcoma as well as metastases.Conclusion: Bone scan is a popular imaging modality for skeletal survey of paediatric patients in malignancy, both primary and metastatic bone diseases. Bone scanning in paediatric patients contributes a major role in detecting the cause and localizing the pathology of bone. High quality imaging, interpreted by physicians familiar with paediatric diseases, correlation with clinical records and other imaging are mandatory to maximize the benefit.Bangladesh J. Nuclear Med. 19(1): 28-31, January 2016

scholarly journals Ewing's sarcoma of rib

2018 ◽  
Vol 50 (1-2) ◽  
pp. 41-43
Author(s):  
Sk Moazzem Hossain ◽  
Farjana Kabir ◽  
SM Kamal ◽  
Debasish Kumar Ghosh
Keyword(s):  
Pleural Effusion ◽  
Chest Wall ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Bone Tumour ◽  
Mass Lesion ◽  
College Hospital ◽  
X Ray ◽  
Medical College ◽  
First Rib

Ewing's sarcoma is an uncommon malignant bone tumour occuring in children, adolescents and young adults. We report a case of a 13 year old male admitted to Khulna Medical College Hospital with history of pain and swelling in chest wall for two weeks. Earlier chest X-ray showed a mass lesion in the left upper part of chest wall and erosion of first rib. Subsequent X-ray revealed left sided massive pleural effusion. CT scan revealed a mass lesion in the left upper part of chest wall originated from left first rib and left sided pleural effusion. FNAC from the mass lesion revealed features suggestive of Ewing's sarcoma. Patient was treated with chemotherapy and after first cycle there was significant improvement of all the signs and symptoms.Bang Med J (Khulna) 2017; 50 : 41-43

Brain and bone scans in primary Ewing's sarcoma of the petrous bone

1976 ◽  
Vol 44 (5) ◽  
pp. 608-612 ◽  
Author(s):  
Pete M. Fitzer ◽  
William R. Steffey
Keyword(s):  
Bone Scan ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Petrous Bone ◽  
Diagnosis And Treatment ◽  
Content Type ◽  
Brain Scan ◽  
Bone Scans ◽  
The Right ◽  
Fine Print

✓ The authors present a case in which primary Ewing's sarcoma of the right petrous pyramid in a 9-year-old girl showed no uptake on a 99mTc-pertechnetate nuclide angiogram. Intense uptake was present on a 99mTc-polyphosphate bone scan, but a static brain scan was only minimally abnormal. The diagnosis and treatment of Ewing's sarcoma are reviewed.

Prognostic features of Ewing's sarcoma on radionuclide bone scan after initial treatment

1994 ◽  
Vol 19 (1) ◽  
pp. 1-6 ◽  
Author(s):  
William R. Reinus ◽  
Louis A. Gilula ◽  
Sarah S. Donaldson ◽  
Jonathan Shuster ◽  
Teresa Vietti
Keyword(s):  
Initial Treatment ◽  
Bone Scan ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Prognostic Features

scholarly journals Pelvic Ewing's Sarcoma: A Review from Scottish Bone Tumour Registry

2008 ◽  
Vol 16 (3) ◽  
pp. 333-338 ◽  
Author(s):  
S Bhagat ◽  
H Sharma ◽  
DS Pillai ◽  
MJ Jane
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Bone Tumour

scholarly journals Primary Ewing’s Sarcoma of the Spine in a Two-Year-Old Boy

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Ali J. Electricwala ◽  
Jaffer T. Electricwala
Keyword(s):  
Spinal Canal ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Cauda Equina ◽  
Bone Tumour ◽  
Tracer Uptake ◽  
Tumour Mass ◽  
Gene Testing ◽  
Bone Sarcomas ◽  
Good Improvement

Ewing’s Sarcoma (ES) is a highly malignant bone tumour. It may involve any part of the skeleton but the most frequent parts are the ilium and diaphysis of femur and tibia (Alfeeli et al., 2005; Zhu et al., 2012). Primary ES of the spine is extremely rare (Yan et al., 2011). It accounts for only 3.5 to 14.9 percent of all primary bone sarcomas. The age of presentation ranges from 12 to 24 years (median 21 years) (Ferguson, 1999; Sharafuddin et al., 1992; Klimo Jr. et al., 2009). We report an unusual case of primary ES of the spine in a two-year-old boy, who presented to us with paraparesis and features of cauda equina syndrome. MRI scan showed a tumour mass arising from the pedicle of L4 vertebra invading the spinal canal. Tc-99 bone scan showed increased tracer uptake in L4 vertebra and normal tracer uptake elsewhere in the skeleton. After reaching the diagnosis of a space occupying lesion invading the lumber spinal canal, we performed a decompressive laminectomy and a biopsy was sent which confirmed the diagnosis of ES. Immunohistochemistry showed tumour cells staining positive for CD-99 (specific stain for ES). Gene testing showed an EWS-FLI 1 chimera. Surgery was followed by good improvement in motor signs. The child was then referred to a specialized oncotherapy centre for further treatment, radiation, and chemotherapy. To the best of our knowledge, we are the first to report primary ES of the spine at the age of two years.

scholarly journals Primary renal Ewing’s sarcoma in an adult: an enigma

2021 ◽  
Vol 5 (3-4) ◽  
pp. 111-113
Author(s):  
Suvraraj Das ◽  
Gaurav Aggarwal ◽  
Sujoy Gupta ◽  
Divya Midha
Keyword(s):  
Renal Vein ◽  
Radical Nephrectomy ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Imaging Modality ◽  
Therapeutic Option ◽  
Left Renal Vein ◽  
In Situ Hybridisation ◽  
Imaging Features ◽  
Ultrasound Evaluation

AbstractObjectivesExtraskeletal Ewing’s sarcoma is a rarity, with a renal primary in an adult, being even rarer. There is no consensus on the optimal imaging modality, as well as best therapeutic option, making them an enigma for clinicians.Case presentationWe report the case of a 34-year-old lady, a known case of invasive lobular carcinoma of the left breast (ER,PR positive, Her2neu negative), having completed treatment in 2017, wherein, on an ultrasound evaluation for left flank pain, was incidentally found to have a left renal mass. A CT scan corroborated with the ultrasound, with an additional Level 1, left renal vein thrombus. She underwent an open left radical nephrectomy with renal vein thrombectomy. Histopathology of the resected tumor revealed features of Ewing’s sarcoma of the kidney, confirmed by Fluorescent In Situ Hybridisation (FISH) and Immunohistochemistry (IHC).ConclusionPrimary renal Ewing’s sarcoma in an adult is a rare occurrence, with no characteristic imaging features, and no universally accepted guideline based management protocols. Akin with standard Ewings sarcoma treatment strategies, a margin negative- radical nephrectomy with adjuvant chemotherapy, seems the most apt treatment strategy.

scholarly journals Ewing’s sarcoma of fifth metacarpal with lung metastasis in a child: an unusual presentation

2017 ◽  
Vol 4 (5) ◽  
pp. 1903
Author(s):  
Nidhi N. Singh ◽  
V. Gupta ◽  
Ashutosh K. Singh
Keyword(s):  
Local Recurrence ◽  
Lung Metastasis ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Bone Tumour ◽  
Long Bones ◽  
Primary Surgery ◽  
Ewings Sarcoma ◽  
Poorly Differentiated ◽  
Small Bones

Ewing’s sarcoma is the second most common bone tumour second only to osteosarcoma which represents a family of malignancies of neuroendothelial origin, which are highly aggressive and poorly differentiated. The most frequent sites involved are shaft of long bones such as femur, tibia and flat bones such as pelvis and vertebra. Ewing’s sarcoma of small bones of hands is very rare and distant metastasis with hands as the primary is even rarer. Here we describe the course of a 11-year-old male who presented with ewings sarcoma of fifth metacarpal who presented with lung metastasis without local recurrence of the disease after primary surgery and later succumbed to his illness.

scholarly journals Primary Ewing’s sarcoma of the temporal bone: a rare entity and review of the literature

2019 ◽  
Vol 12 (10) ◽  
pp. e230768
Author(s):  
Jeewan Ram Vishnoi ◽  
Vijay Kumar ◽  
Kirti Srivastava ◽  
Sanjeev Misra
Keyword(s):  
Temporal Bone ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Bone Tumour ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Radiological Features ◽  
Primary Bone Tumour ◽  
Primary Bone ◽  
Multiagent Chemotherapy

Ewing’s sarcoma (ES) is the second most common malignant primary bone tumour in children and adolescents. It primarily affects the diaphysis of long bones and pelvis. ES arising from temporal bone is extremely rare. To date, 43 such cases have been described in the literature. Clinical and radiological features are non-specific. Diagnosis is based mainly on immunohistochemistry. The present article presents an extremely rare case of ES of the temporal bone in a 20-year young man, and he was successfully treated with multiagent chemotherapy and radiotherapy.

scholarly journals Extraskeletal Ewing’s Sarcoma Arising from the Sciatic Nerve: A Diagnostic Challenge

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Aadhar Sharma ◽  
Kate Brown ◽  
John Skinner ◽  
Jeremy Whelan ◽  
Michael Fox
Keyword(s):  
Sciatic Nerve ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Bone Tumour ◽  
Excision Biopsy ◽  
Diagnostic Challenge ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Extraskeletal Ewing’S Sarcoma ◽  
Extraosseous Ewing’S Sarcoma

Ewing’s sarcoma is a common bone tumour of childhood but is a rare occurrence in individuals over 20 years of age. Few cases are reported as originating from peripheral nerves. We present an unusual case of extraosseous Ewing’s sarcoma originating from the sciatic nerve in a 66-year-old patient which had the clinical hallmarks of a benign nerve sheath tumour. Following discussion at a multidisciplinary meeting, excision biopsy of the suspected benign nerve sheath tumour was planned. At operation, the mass had malignant features. Histology confirmed the presence of Ewing’s sarcoma. Due to the morbidity of nerve resection, radiotherapy and chemotherapy were commenced. Ewing’s sarcoma is known to mimic benign pathologies. In this case there were subtle signs of a malignant process in the form of unremitting pain. It is vital to keep in mind the less common tumours that can affect the peripheral nervous system in such cases.

scholarly journals The Use of Cone Beam Computed Tomographic Imaging in a Paediatric Dentistry Department

Oral ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 45-55
Author(s):  
Claudy Henein ◽  
Shannu K Bhatia ◽  
Nicholas Drage
Keyword(s):  
Root Resorption ◽  
Imaging Modality ◽  
Treatment Plan ◽  
Service Evaluation ◽  
Paediatric Dentistry ◽  
Cone Beam ◽  
Definitive Treatment ◽  
Or Management ◽  
Paediatric Patients ◽  
Clinical Records

Cone beam computed tomography (CBCT) is an emerging radiographic imaging modality. The diagnostic benefit must exceed the individual detriment that its generally higher radiation exposure may cause. Since limited studies exist on the use and impact of CBCT in paediatric dentistry, a service evaluation was carried out to explore the reasons for CBCT referral and to identify its impact on the treatment plan and/or management in a paediatric dentistry department. Clinical records for all paediatric patients who underwent a CBCT were reviewed, to identify the reason for referral and its influence on diagnosis or management, by comparing the provisional treatment plan with the definitive treatment plan, post-CBCT. A total of 130 paediatric patients underwent CBCT in a 12-month period, of which 52 satisfied the inclusion criteria. CBCTs were most commonly requested for the localisation of unerupted/impacted teeth 14/52 (27%), assessment of supernumerary teeth 12/52 (23%), and to investigate root resorption 9/52 (17%). All CBCTs provided additional information that assisted treatment planning, diagnosis, or management and, most significantly, 16/52 (31%) of treatment plans were changed based on CBCT findings. All CBCTs requested in this study were justified and confirmed or influenced the management of paediatric patients, ultimately reducing the risk of complications and further treatment.

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