scholarly journals SEROPREVALENCE OF EQUINE BRUCELLOSIS: FIRST REPORT IN BANGLADESH

2018 ◽  
Vol 16 (1) ◽  
pp. 103-106
Author(s):  
M. K. S. A. Millat ◽  
N. M. Shafy ◽  
S. T. Sharmy ◽  
F. Yeasmin ◽  
M. F. Karim ◽  
...  
Keyword(s):  
High Risk ◽  
Rose Bengal ◽  
Control Strategies ◽  
First Report ◽  
Brucella Infection ◽  
Rose Bengal Test ◽  
Positive Reactor ◽  
And Control ◽  
The Rose

Despite the endemicity of brucellosis, there is no report on the equine brucellosis in Bangladesh. The Rose Bengal Test (RBT) was used to determine the seroprevalence of Brucella antibodies amongst 112 horses from different areas of Bangladesh. The overall seroprevalence of equine brucellosis was 1.79%.The prevalence recorded in Ghatail area was 3.45% and there was no positive reactor in Shakipur and Savar areas. Sex wise prevalence showed that the prevalence was 3.08%in female and 0.00% in male horse. Only the adult (>3 years of old) horses showed the positive RBT reaction (2.35%), whereas young (<3 years of old) horses did not showed positive RBT reaction. The present study reports the first serological prevalence of Brucella infection in horses in Bangladesh. There is need for the inclusion of horses in brucellosis surveillance and control strategies in Bangladesh to safeguard people from high risk.

scholarly journals The Rose Bengal Test in Human Brucellosis: A Neglected Test for the Diagnosis of a Neglected Disease

2011 ◽  
Vol 5 (4) ◽  
pp. e950 ◽  
Author(s):  
Ramón Díaz ◽  
Aurora Casanova ◽  
Javier Ariza ◽  
Ignacio Moriyón
Keyword(s):  
Rose Bengal ◽  
Human Brucellosis ◽  
Neglected Disease ◽  
Rose Bengal Test ◽  
The Rose

The Rose Bengal Test of Liver Function

1933 ◽  
Vol 3 (1) ◽  
pp. 55-60 ◽  
Author(s):  
W. Parker Stowe ◽  
G. D. Delprat ◽  
Alanson Weeks
Keyword(s):  
Liver Function ◽  
Rose Bengal ◽  
Rose Bengal Test ◽  
The Rose

scholarly journals The measurement and control of high-risk host cell proteins for polysorbate degradation in biologics formulation

2022 ◽  
Author(s):  
Xuanwen Li ◽  
Fengqiang Wang ◽  
Hong Li ◽  
Douglas D Richardson ◽  
David J Roush
Keyword(s):  
High Risk ◽  
Host Cell ◽  
Method Development ◽  
Control Strategies ◽  
Ionic Surfactant ◽  
Formulation Development ◽  
High Concentration ◽  
Host Cell Proteins ◽  
And Control ◽  
Measurement And Control

Abstract Non-ionic surfactant polysorbates (PS), including PS-80 and PS-20, are commonly used in the formulation of biotherapeutic products for both preventing surface adsorption and acting as stabilizer against protein aggregation. Trace levels of residual host cell proteins (HCPs) with lipase or esterase enzymatic activity have been shown to degrade polysorbates in biologics formulation. The measurement and control of these low-abundance, high-risk HCPs for polysorbate degradation is an industry-wide challenge to achieve desired shelf-life of biopharmaceuticals in liquid formulation, especially for high-concentration formulation product development. Here, we reviewed the challenges, recent advances and future opportunities of analytical method development, risk assessment and control strategies for polysorbate degradation during formulation development with a focus on enzymatic degradation. Continued efforts to advance our understanding of polysorbate degradation in biologics formulation will help develop high-quality medicines for patients.

scholarly journals Effects of the proportion of high-risk patients and control strategies on the prevalence of methicillin-resistant Staphylococcus aureus in an intensive care unit

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Farida Chamchod ◽  
Prasit Palittapongarnpim
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
High Risk ◽  
Risk Group ◽  
Control Strategies ◽  
High Risk Group ◽  
High Risk Patients ◽  
Risk Patients ◽  
Mrsa Infection ◽  
And Control

Abstract Background The presence of nosocomial pathogens in many intensive care units poses a threat to patients and public health worldwide. Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen endemic in many hospital settings. Patients who are colonized with MRSA may develop an infection that can complicate their prior illness. Methods A mathematical model to describe transmission dynamics of MRSA among high-risk and low-risk patients in an intensive care unit (ICU) via hands of health care workers is developed. We aim to explore the effects of the proportion of high-risk patients, the admission proportions of colonized and infected patients, the probability of developing an MRSA infection, and control strategies on MRSA prevalence among patients. Results The increasing proportion of colonized and infected patients at admission, along with the higher proportion of high-risk patients in an ICU, may significantly increase MRSA prevalence. In addition, the prevalence becomes higher if patients in the high-risk group are more likely to develop an MRSA infection. Our results also suggest that additional infection prevention and control measures targeting high-risk patients may considerably help reduce MRSA prevalence as compared to those targeting low-risk patients. Conclusions The proportion of high-risk patients and the proportion of colonized and infected patients in the high-risk group at admission may play an important role on MRSA prevalence. Control strategies targeting high-risk patients may help reduce MRSA prevalence.

The first report and control strategies ofTuta absolutain Iran

EPPO Bulletin ◽  
2012 ◽  
Vol 42 (2) ◽  
pp. 322-324 ◽  
Author(s):  
V. Baniameri ◽  
A. Cheraghian
Keyword(s):  
Control Strategies ◽  
First Report ◽  
And Control

scholarly journals Rose Bengal plate agglutination and counterimmunoelectrophoresis tests on spinal fluid in the diagnosis of Brucella meningitis

1978 ◽  
Vol 7 (2) ◽  
pp. 236-237
Author(s):  
R Díaz ◽  
E Maraví-Poma ◽  
G Delgado ◽  
A Rivero
Keyword(s):  
Cerebrospinal Fluid ◽  
Rose Bengal ◽  
Immunoglobulin G ◽  
Rapid Diagnosis ◽  
Spinal Fluid ◽  
Rose Bengal Test ◽  
The Rose

Rose Bengal and counterimmunoelectrophoresis, two tests that detect antibodies against different structural antigens, when carried out on spinal fluid permitted rapid diagnosis of human Brucella meningitis. The Rose Bengal test was positive in five out of five patients studied, and counterimmunoelectrophoresis was positive in all but one. The Brucella meningitis was characterized by an increase of immunoglobulin G in the cerebrospinal fluid.

scholarly journals The Use Of Alternative Stain In Rose Bengal Test Antigen Preparation Which Specific For Brucellosis.

2006 ◽  
Vol 30 (2) ◽  
pp. 56-64
Author(s):  
Erada A .J . Saeed
Keyword(s):  
Serum Sample ◽  
Rose Bengal ◽  
Screening Test ◽  
Serum Samples ◽  
Antigen Preparation ◽  
Specific Antibodies ◽  
Rose Bengal Test ◽  
The Rose ◽  
Food Colours ◽  
Standard Tests

The Rose Bengal test is one of the famous diagnostic test of Brucellosisspecially as a screening test in order to detect the infection in limited area.Rose Bengal standard stain which producd by specific companies was used inpreparation of the test special antigen , The stain gives the known pink colourfor the antigen during the test that make the agglutination in positive cases morevisible due to the reaction between antigen and the specific antibodies ofBrucella which found in the serum sample of human and different animals.Antigen for the Rose Bengal test in this study is prepared by using alternativestain easily found in local supermarkets using for food colours and notexpensive like standard stain. All standard tests were down for the stain like thecolour ,pH, stability are same for two stains until the date of expire of antigen.The antigen prepared with alternative stain was used in comparative with theantigen prepared with standard stain for testing serum samples of human anddifferent animals, the results deal no significant different statistically betweenthem that means as a result we can prepare antigen more easily and notexpensive.

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