An Assessment of Serum Cholesterol level and BMI in Women: Study in Several Private Chambers in Mymensingh

2019 ◽  
Vol 8 (2) ◽  
pp. 4-9
Author(s):  
Nahid Bintay Ansary ◽  
Arup Ratan Paul ◽  
Md Mahamudur Rahman ◽  
Maria Hussain ◽  
Rubiat Naznin

The increased risk of cardiovascular disease associated with higher serum cholesterol levels in middle-aged persons has been established, but there have been few studies conducted regarding the issues in Mymensingh. For evaluation of serum cholesterol and BMI in women of Mymensingh, across-sectional studywas conducted in several private chambers in the districts of Mymensingh, Bangladesh during the period from January 2017 to December 2017. A total of 48 Female patients participated in the study. In the study, participants were aged between 18 to 29 years of age. The study suggested that the serum cholesterol was below 4.99 were 15(31.25%), 5.00 to 6.49 were 13(26.08%) and above 6.50 were 20 (41.67%), the Mean ± SD was 4.45 (0.76). The health status according to BMI showed that 12.50% (n=6) of the participants were underweight <18.49, majority 50.00% (n=24) of the population were from normal weight range (18.5-24.9), 16.67% (n=8) of the participants were overweight and 20.83 %( n=10) of the participants were obese >30. The Mean ± SD was 18.93± (3.68). Measurement of BMI and Serum Cholesterol levels can help doctors to treat patients properly for reducing the burden of death in our country. CBMJ 2019 July: Vol. 08 No. 02 P: 4-9

2016 ◽  
Vol 7 (2) ◽  
pp. 91
Author(s):  
Mohammad Aftabuddin ◽  
Mohammed Irfan ◽  
Omar Sadeque Khan ◽  
Khan Mohammad Amanur Rahman ◽  
Md. Rezwanul Hoque ◽  
...  

<p><strong>Background:</strong> Since the development of atherosclerosis involves dyslipidemia, we postulated that green tea may exert lowering of serum cholesterol levels. Objectives: To investigate the effects of green tea on serum cholesterol level. Methods: Total 45 rabbits (15 were fed on 1% cholesterol and green tea for 16 weeks, another 15 were fed on 1% cholesterol and plain water for 16 weeks, last batch of 15 rabbits received normal rabbit diet for 16 weeks) in the department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka from April 2011 to September 2012.They were evaluated for lipid profile and presence of atherosclerosis. Results: The mean total cholesterol in cholesterol fed rabbits with green tea after 16 weeks was 21.06 ± 5.55, LDL-C was 20.80 ± 6.16, Serum TG was 153.67 ± 33.59, HDL-C neither increased nor decreased. The mean total cholesterol in cholesterol fed rabbits with plain water after 16 weeks was 27 .53 ± 5.15, LDL-C was 32.40 ± 8.24 and TG was 290.13 ± 44.31, no effect were seen on HDL-C. These rabbits were fed on green tea for 8 weeks, cholesterol levels returned to levels at commencement of experiment. Rabbits fed on normal rabbit diet for 16 weeks had TC l9.20 ± 4.85, LDL-C was 19.20 ± 2.04 and TG was 155.06 ± 32.03 mg/dl. HDL-C remained in normal range. But there was no atheroschlerotic change in any group. Conclusion: Green tea significantly reduces serum cholesterol levels in cholesterol fed rabbits. There was no effect of green tea on HDL-C in any group.</p>


1970 ◽  
Vol 17 (1) ◽  
pp. 13-15
Author(s):  
M Samiul Hafiz ◽  
M Iqbal Arslan ◽  
Sajal Banarjee ◽  
M Obaidullah

Myocardial Infarction (MI) is the most common form of heart disease and the single most important cause of premature death in the developed and developing world. Unfortunately the incidence of the condition is increasing rapidly in many developing countries like Bangladesh. Effort should therefore be taken to minimize the risk factors of MI. Large scale randomized clinical trials have shown that lowering high cholesterol concentration mainly by drugs reduces the risk of cardiac events like MI. This study was designed to see the serum cholesterol levels in normal healthy subjects, to compare serum cholesterol levels in patients with MI and those of healthy subjects and to evaluate the association of serum cholesterol level in Bangladesh MI patients. The present study was carried out in the Department of Biochemistry, BSMMU in collaboration with Department of Cardiology, BSMMU and NICVD, Dhaka during the period of July 2001 to December 2002. A total of 50 subjects were selected, Group A (30 subjects of Control) and Group B (20 subjects of MI). The mean level of serum cholesterol in control subjects were 145.07 ± 31.39 mg/dl and in test subjects were 226.91 ± 44.38 mg/dl. This study showed that serum cholesterol level was significantly higher in patients with MI. From the present study, it is difficult to draw any definite conclusion but suggested that high serum cholesterol concentration plays a crucial role in the pathogenesis of MI.   doi: 10.3329/taj.v17i1.3483 TAJ 2004; 17(1) : 13-15


1964 ◽  
Vol 42 (2) ◽  
pp. 179-185 ◽  
Author(s):  
P. J. Lupien ◽  
B. B. Migicovsky

The serum cholesterol level and the degree of incorporation of C14-acetate and C14-mevalonate into liver cholesterol has been studied in normal and deutectomized chicks.Serum and liver cholesterol levels in normal chicks decreased rapidly between 3 days and 5 days after hatching, and at 9 days of age the quantity of cholesterol stabilized at levels comparable to those of mature birds.Deutectomy significantly lowered serum cholesterol levels of the 5-day-old chicks but did not affect liver cholesterol levels.High levels of liver cholesterol in the 3-day-old chicks did not totally depress C14-acetate incorporation. Minimal C14-acetate incorporation was obtained when the chicks were 5 days of age and maximal incorporation occurred on the 15th day following hatching. C14-mevalonate incorporation into liver cholesterol was observed to be minimal when the chicks were 3 days of age and maximal when the chicks were 12 days of age.It is suggested that the chick might prove to be of value for the study of the control mechanisms in cholesterol metabolism.


2021 ◽  
Author(s):  
Li-Tao Tong ◽  
Tianzhen Xiao ◽  
Lili Wang ◽  
Cong Lu ◽  
Liya Liu ◽  
...  

Abstract Background: Epidemiological and experimental studies have indicated that an increase of plant proteins in diets, as well as a substitution of red meat proteins or processed meat proteins with plant proteins, was closely associated with the reduction of cardio-cerebrovascular disease (CVD)-related mortality. One of the most important ways of plant proteins to reduce the incidence rate of CVD is to lowering cholesterol concentration in serum and liver. Mounting evidences have attributed this effect of plant proteins to their regulation of gut microbiota. However, it remains to be elucidated whether gut microbiota play decisive roles in modulating host cholesterol by dietary protein from diverse sources of plant or meat. This study attempted to clarify the relevant mechanisms by comparing the difference in cholesterol metabolism modulation between pea and pork proteins intake of hypercholesterolemia hamster, as well as its relationships with gut microbiome and metabolic pathway.Results: We have verified that there are significant differences in the regulations of serum and liver cholesterol levels among different proteins intake from plants (rice, oat, soybean, pea) or meat (chicken, pork, beef), and the corresponded differences in gut microbiota were also observed. The decisive roles of gut microbiota in regulating host cholesterol were illustrated by the findings that the differences in serum cholesterol level between pea protein and pork protein disappeared in the hamsters treated with antibiotics. The experimental results of cross-over intervention of pea and pork protein showed that the serum cholesterol level was reversed with dietary exchange. Most interestingly, the corresponded changes in abundance of dominant bacteria suggested that the “beneficial” microbe Muribaculaceae were responsible for the inhibitory effect of pea protein on serum cholesterol level, while the opposite effect of pork protein was due to the “harmful” microbe Erysipelotrichaceae. Moreover, dietary pea protein supplement altered cecal metabolites including changes in arginine/histidine pathway, primary bile acid biosynthesis, short chain fatty acids or other lipid-like molecules, which involved in cholesterol metabolism.Conclusion: Dietary pea protein exerted cholesterol-lowering effects through modulating the growth of selected gut microbiota in hamsters. The substitution of pork protein with pea protein could reshape the gut microbiota, affect the contents of metabolites in caecum, and thus regulate cholesterol metabolism. These findings suggest specific bacteria and metabolites can be potential therapeutic targets of hypercholesterolemia by plant protein intervention.


1960 ◽  
Vol 21 (1) ◽  
pp. 69-82 ◽  
Author(s):  
W. F. J. CUTHBERTSON ◽  
P. V. ELCOATE ◽  
D. M. IRELAND ◽  
D. C. B. MILLS ◽  
PATRICIA SHEARLEY

SUMMARY 1. Atherosclerotic lesions can be made to develop or regress in the albino rat by treatments that, respectively, elevate or depress the serum cholesterol concentration. 2. After young rats had been given a new diet for 45–72 days, the degree of atherosclerosis attained was related to the new serum cholesterol level and was independent of the previous degree and severity of atherosclerosis. 3. Regression of lesions established for about 1 month occurred if the serum cholesterol level was lowered, either by changes in the diet or by administering 3:5-diiodo-d-thyronine (DT2). The relation between serum cholesterol level and Sudan score (see p. 70) appeared to be independent of the method used for lowering the serum cholesterol level. 4. Regression of lesions established for about 6 months occurred if the serum cholesterol level was lowered either by changes in the diet or by administering DT2, but the rate of regression was slower than when the lesions had been present for a short time only. 5. When the serum cholesterol levels of rats given an atherogenic diet for 6 months had been reduced to normal values by feeding stock diet, the rats still had a high degree of atherosclerosis. When stock diet containing DT2 was then fed, there was no increase in the rate of regression of lesions over that obtained on the stock diet alone. 6. Dietary administration of different amounts of 3:5-diiodo-4(4′-hydroxy phenoxy) phenyl acetic acid (DIAC) or DT2 to groups of rats maintained on a diet containing cholesterol and cholic acid over a 9-month period resulted in a reduction of serum cholesterol levels to an extent roughly related to the dose of drug given. Liver cholesterol levels were also reduced in the older animals. Arterial atheroma was reduced by both compounds to an extent proportional to the dose administered. Both compounds, at all dose levels, increased the rate of growth of animals compared with that of controls. Both compounds depressed liver weights at all dose levels and increased the weight of the pancreas at the higher dose levels, if these weights were expressed per 100 g/body weight.


2018 ◽  
Vol 16 (1) ◽  
pp. 1 ◽  
Author(s):  
AZRUL HILDAN SAFRIZAL

<p>The pattern and lifestyle of today's society with the presence of an interner facility makes people spend more time sitting out than on exercise and increased consumption of high-fat foods may increase the risk of cardiovascular disease. An effective therapy is needed in preventing the occurrence of cardiovascular disease. Hyperbaric oxygen now starts to develop for the treatment of several diseases, which in turn can increase the gene forming antioxidant enzymes and ROS. To determine effect of hyperbaric oxygen therapy on total cholesterol levels of wistar white rats (Rattusnovergicus) induced bye high fat. The study was carried out in an expeative post test only group control of three groups. One group is given standard feed. All groups induced high-fat diet and standard feed. Of the two groups induced, one group was given hyperbaric oxygen therapy with a dose of 3 x 30 minutes for six days on day 7 at a blood test to determine total cholesterol levels<strong>. </strong>One way Anova parametric statistic test showed that p = 0.007 &lt; α proved hypothesis that hyperbaric oxygen therapy giving effect to total cholesterol level of white mice of jantangalurist rings induced by high fat diet. Total cholesterol was significantly different between K (-) and K (+) and between K (-) and P. It was found that hyperbaric oxygen therapy had an effect on total cholesterol level dose of 3x30 minutes for six days.</p>


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