scholarly journals Prevalence of morbidity and mortality of diabetes mellitus in a rural community cohort

2021 ◽  
Vol 15 (1) ◽  
pp. 31-36
Author(s):  
M Abu Sayeed ◽  
Parvin Akter Khanam ◽  
Akhter Banu ◽  
Khandaker Abul Ahsan ◽  
Fazlul Haq
Keyword(s):  
Diabetes Mellitus ◽  
Renal Disease ◽  
Rural Community ◽  
End Stage Renal Disease ◽  
Morbidity And Mortality ◽  
Past Century ◽  
Study Cohort ◽  
Double Burden ◽  
Stage Renal Disease ◽  
End Stage

Background and objectives: The developing countries are facing the double burden of the communicable (CD) and non-communicable (NCD) diseases. The initiation of primary health care (PHC) adopted in the past century, which included sanitation and immunization, remarkably reduced the load of CDs in the least developing nations. The burden of NCDs remained the same or showed an increasing trend. Of the NCDs, diabetes has become a serious threat to human health and the related morbidity and mortalities are affecting the younger people. As a consequence, the disease complications render huge number of people to disabilities and unusual enormous health expenditures. Very few studies addressed the prevalence of complications among the diabetes patients in a rural community.  This study aimed to determine the prevalence of sequels (morbidity and mortality) among the diabetic cases eight years after the initial diagnosis of diabetes in a rural community cohort Subjects and Methods: A rural community survey in 10 villages was conducted in 1993. The survey screened 1319 (797 men, 522 women) for diabetes mellitus (DM) and impaired glucose tolerance (IGT). Those who were diagnosed DM and IGT referred to a referral center (BIRDEM) for registration. A retrospective cohort was designed in 2001. The addresses of the patients were retrieved from the BIRDEM registry. These registered patients, both survivors and non-survivors, were traced in ten villages. The survivors were investigated (anthropometry, glycemia, fundoscopy, urine protein etc.). A verbal autopsy was performed to determine the cause(s) of death in the non-survivors. Results: Of the188 registered cases, 79 were found and located (survivors 43 (54.4%, non-survivors 36 (45.6%). Of the survivors, 44.2% developed complications. The observed complications were sensory neuropathy 16.3%, CAD 9.3%, retinopathy 7% and nephropathy 4.7%. Among the non-survivors, 19.4% were found to have nephropathy leading to end-stage renal disease. Conclusions: The study cohort revealed that more than one-third of the people with diabetes died in less than ten years after being diagnosed. The cohort also revealed that diabetic nephropathy (end-stage renal disease) and dearth of dialysis facilities contributed to early death in the rural community. Among the complications, most frequent incidence was neuropathy and neuro-psychiatric disorders. Ibrahim Med. Coll. J. 2021; 15(1): 31-36

The effect of diabetes mellitus and end-stage renal disease on the number of CD34+ cells in the blood

2013 ◽  
Vol 92 (9) ◽  
pp. 1189-1194 ◽  
Author(s):  
Cigdem Pala ◽  
Ilker Altun ◽  
Yavuz Koker ◽  
Fatih Kurnaz ◽  
Serdar Sivgin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Cd34 Cells ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Association between End-Stage Renal Disease and Incident Diabetes Mellitus—A Nationwide Population-Based Cohort Study

2018 ◽  
Vol 7 (10) ◽  
pp. 343 ◽  
Author(s):  
Pin-Pin Wu ◽  
Chew-Teng Kor ◽  
Ming-Chia Hsieh ◽  
Yao-Peng Hsieh
Keyword(s):  
Diabetes Mellitus ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Lower Risk ◽  
Incident Diabetes ◽  
P Value ◽  
Comparison Cohort ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: Glucose is one of the constituents in hemodialysates and peritoneal dialysates. How the dialysis associates with the incident diabetes mellitus (DM) remains to be assessed. Methods: The claim data of end-stage renal disease (ESRD) patients who initiated dialysis from and a cohort of matched non-dialysis individuals from 2000 to 2013 were retrieved from the Taiwan National Health Insurance Research Database to examine the risk of incident DM among patients on hemodialysis (HD) and peritoneal dialysis (PD). Predictors of incident DM were determined for HD and PD patients using Fine and Gray models to treat death as a competing event, respectively. Results: A total of 2228 patients on dialysis (2092 HD and 136 PD) and 8912 non-dialysis individuals were the study population. The PD and HD patients had 12 and 97 new-onset of DM (incidence rates of 15.98 and 8.69 per 1000 patient-years, respectively), while the comparison cohort had 869 DM events with the incidence rate of 15.88 per 1000 patient-years. The multivariable-adjusted Cox models of Fine and Gray method showed that the dialysis cohort was associated with an adjusted hazard ratio (HR) of 0.49 (95% CI 0.39–0.61, p value < 0.0001) for incident DM compared with the comparison cohort. The adjusted HR of incident DM was 0.46 (95% CI 0.37–0.58, p value < 0.0001) for HD and 0.84 (95% CI 0.47–1.51, p value = 0.56) for PD. Conclusions: ESRD patients were associated with a lower risk of incident DM. HD was associated with a lower risk of incident DM, whereas PD was not.

Effects of two different dialytic treatments on inflammatory markers in people with end-stage renal disease with and without type 2 diabetes mellitus

Cytokine ◽  
2017 ◽  
Vol 92 ◽  
pp. 75-79 ◽  
Author(s):  
Giuseppe Derosa ◽  
Carmelo Libetta ◽  
Pasquale Esposito ◽  
Ilaria Borettaz ◽  
Carmine Tinelli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Inflammatory Markers ◽  
Stage Renal Disease ◽  
End Stage

Clinical Considerations in Hemodialysis Access Intervention

2018 ◽  
pp. 594-614
Author(s):  
Eric K. Hoffer
Keyword(s):  
Renal Disease ◽  
Arteriovenous Fistula ◽  
End Stage Renal Disease ◽  
Morbidity And Mortality ◽  
Dialysis Access ◽  
Hemodialysis Access ◽  
National Kidney Foundation ◽  
Clinical Considerations ◽  
Stage Renal Disease ◽  
End Stage

Interventional radiologists developed and refined the endovascular approaches to maintenance of the permanent arteriovenous vascular accesses that are integral to the provision of hemodialysis for patients with end stage renal disease. As methods of percutaneous arteriovenous fistula creation expand the scope of IR, this chapter reviews the clinical indications and preferences pertinent to dialysis access creation with respect to National Kidney Foundation Recommendations. Accesses remain imperfect, plagued by the development of flow-limiting intimal hyperplastic stenoses, and require monitoring and maintenance to minimize complications, morbidity and mortality. The measures of dialysis access function used in the surveillance of vascular accesses that indicate potential stenosis, and the utility of pre-occlusion recanalization of these stenoses are discussed. Complications specific to dialysis access interventions are also addressed.

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