scholarly journals Morphological Pattern of Ovarian Tumour : Experience in a Tertiary Level Hospital

2018 ◽  
Vol 36 (1) ◽  
pp. 5-10
Author(s):  
Mousumi Ahmed ◽  
Nazma Afroze ◽  
Mahjabin Sabiha
Keyword(s):  
Ovarian Neoplasms ◽  
Germ Cell Tumour ◽  
Age Distribution ◽  
Cystic Teratoma ◽  
Ovarian Tumour ◽  
Common Type ◽  
Histological Diagnosis ◽  
Age Group ◽  
Morphological Pattern ◽  
Benign Tumours

Background: Ovarian tumor is a common type of gynecological neoplasm and accounts for 15-25% of all gynecological malignancies. It is associated with high mortality and an accurate histological diagnosis is essential for management of patient.Objective: The study was performed to find out the morphological pattern, nature and age distribution of ovarian tumour in our hospital.Material and methods: It was a prospective study,conducted in the Department of Histopathology and Cytopathology, BIRDEM General Hospital, Dhaka for a period of two years from Jan 2014 to Dec 2015. This study included 186 cases of ovarian tumors sent in the Department of Pathology for histopathological evaluation. Non-neoplastic lesions and tumour-like conditions were excluded from the study. Histological diagnosis, age and laterality of ovary were recorded. Morphological pattern, nature and age distribution of ovarian neoplasms were calculated.Result: 84.95% cases of ovarian tumour were benign, 1.61% cases were borderline and 13.44% cases were malignant. ORIGINAL ARTICLES Surface epithelial tumour was the commonest type of tumour (61.83%), according to the histogenesis , followed by germ cell tumour. Benign serous tumour was the most common type of benign tumor (37.98% cases), followed by mature cystic teratoma (33.55% cases). Serous cystadenocarcinoma was the most common type of malignant tumour (36.0%), followed by endometrioid carcinoma (28.0%). Benign tumours were more frequent in all age group. The incidence of malignant ovarian tumour increased with age and was most frequent in >50 years age group. Benign tumours were commonly cystic, whereas malignant tumours were commonly solid and cystic. 11.23% cases of ovarian tumours were bilateral.Conclusion: Benign ovarian neoplasms were more common than malignant ones and benign serous tumour was the commonest type of benign neoplasm whereas serous cystdenocarcinoma was the commonest type of malignant neoplasm. The pattern and age distribution of ovarian tumour of our study were quite similar with other studies with some variation.J Bangladesh Coll Phys Surg 2018; 36(1): 5-10

scholarly journals Clinicopathological Analysis of Ovarian Tumours at Birendra Military Hospital

2012 ◽  
Vol 10 (1) ◽  
pp. 26-31
Author(s):  
R Khatri
Keyword(s):  
Germ Cell ◽  
Tumour Size ◽  
Germ Cell Tumour ◽  
Cystic Teratoma ◽  
Ovarian Tumour ◽  
Benign Tumour ◽  
Military Hospital ◽  
Age Group ◽  
Ovarian Tumours ◽  
Benign Tumours

Introduction: Ovarian cancer is the second most common genital tract malignancy accounting for 25% gynaecological malignancy. This study was conducted to determine the incidence, epidemiological factors and clinical presentation of different types of ovarian tumours their correlation with histopathology. Methods: This is a descriptive study conducted in Birendra Military Hospital over a period of 2 years. The case records of all the patients with ovarian tumur was analyzed. Results: Of the total of 135 adnexal masses cases 100 (74.07%) were found to be histologically proven ovarian tumour out of which 35 were non neoplastic conditions. Benign tumours comprised of 68 (68%) and 32 (32%) were malignant and borderline.Mature cystic teratoma 28 (75%) was the commonest benign tumour, whereas serous cystadenocarcinoma 13 (64.3%) were commonest malignancy. Age varying from 2.5 yrs. To 70 yrs. Smallest tumour size was 2.5 cm. largest was 40 cm. Commonest symptom was abdominal discomfort and most common sign was abdominal lump. Malignancy usually presented with ascites especially epithelial ovarian tumours. Germ cell tumour was observed in younger age group in earlier stage. Conclusion: The commonest ovarian tumor was epithelial followed by germcell. Mature cystic teratoma was the most common benign tumour and malignant was serous cyst adenocarcinoma. Epithelial ovarian tumour prevalent in perimenopausal and postmenopausal age group whereas germ cell in earlier age. DOI: http://dx.doi.org/10.3126/mjsbh.v10i1.6446 Medical Journal of Shree Birendra Hospital Jan-June 2011 10(1) 26-31

scholarly journals Intestinal Adenocarcinoma Arising from a Mature Cystic Teratoma

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
King Man Wan ◽  
Forough Foroughi ◽  
Rajni Bansal ◽  
Martin K. Oehler
Keyword(s):  
Germ Cell ◽  
Incidence Rate ◽  
Clinical Presentation ◽  
Ovarian Neoplasms ◽  
Germ Cell Tumour ◽  
Cystic Teratoma ◽  
Squamous Cell Carcinomas ◽  
Mature Cystic Teratoma ◽  
Histopathological Diagnosis ◽  
Common Malignancy

Mature cystic teratomas are the most common ovarian germ cell tumour and account for 10–20% of all ovarian neoplasms. Malignant transformation of mature cystic teratomas is rare and has an incidence rate of less than 1%. The most common malignancy are squamous cell carcinomas. Here we present the case of an intestinal adenocarcinoma which is an exceedingly rare malignant entity arising within a mature cystic teratoma. Clinical presentation, imaging and histopathological diagnosis are discussed and previously presented cases in the literature reviewed.

scholarly journals Spectrum of ovarian tumors in a referral hospital in Nepal

2014 ◽  
Vol 4 (7) ◽  
pp. 539-543 ◽  
Author(s):  
S Vaidya ◽  
P Sharma ◽  
S KC ◽  
SA Vaidya
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumour ◽  
Age Distribution ◽  
Germ Cell Tumors ◽  
Clinical Manifestations ◽  
Cystic Teratoma ◽  
Ovarian Tumors ◽  
Serous Carcinoma ◽  
Benign Tumors ◽  
Malignant Germ Cell Tumors

Background: Ovarian tumors are common forms of neoplasia in women. Among cancers of the female genital tract, it ranks only below carcinoma of the cervix and the endometrium, but is responsible for approximately 50% of the deaths. They arise from different cell lineages and hence constitute a wide variety of neoplastic entities with diverse morphological and clinical manifestations. Materials and Methods: A descriptive study of 363 cases of ovarian tumors was carried out during a three year period from January 2011 to December 2013. Results: Of the 363 ovarian tumors, 293 (80.72%) cases were benign, 57 (15.70%) were malignant and 13 (3.58%) were borderline. Germ cell tumour was the most common class of tumour and seen in 187 (51.52%) cases, followed by surface epithelial in 158 (43.53%) cases. The age distribution of the patients ranged from 10-82 years with a median age of 33 years. Benign tumors were more common than malignant ones in all age groups. Conclusion: Most of the ovarian tumors in this study were of germ cell origin. The incidence of malignant germ cell tumors was also significantly higher than in other studies. Mature cystic teratoma was the most common benign tumour while serous carcinoma was the most common malignancy. The incidence of malignant germ cell tumors was higher compared to other studies. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10295 Journal of Pathology of Nepal (2014) Vol. 4, 539-543

scholarly journals Dermatological adverse drug reactions in tertiary care hospital: an analysis of causality and severity

2018 ◽  
Vol 7 (8) ◽  
pp. 1620
Author(s):  
Kalpana R. Bharani ◽  
Nitibhushansingh R. Chandel ◽  
Chhaya A. Goyal
Keyword(s):  
Adverse Drug Reactions ◽  
Tertiary Care ◽  
Age Distribution ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Drug Reactions ◽  
Morphological Pattern ◽  
Cross Sectional ◽  
Moderate Severity

Background: Dermatological adverse drug reactions (ADRs) are easily detected by patients and that precludes further usage of drugs. So, decided to study the pattern, causative drugs, severity of adverse drug reactions and their causality in tertiary care hospital.Methods: It was prospective non inventional cross sectional study. Patients attending OPD or admitted to IPD of all age group and both gender with suspected dermatological ADRs following drug intake were included and the ADRS were recorded on CDSCO’s Pharmacovigilance form. Collected data was analyzed for assessment of causality using WHO-UMC scale, for severity by using Modified Hartwig and Siegel. Morphological pattern, drug groups, gender and age distribution was analyzed.Results: 231 dermatological ADRs were recorded and analyzed. Maximum cases were found in 21-30 years age group (74 cases). Dermatological ADRs were found in 143 females and in 88 males. Three major classes of drugs found responsible for causing dermatological ADRs were -oral Antimicrobials-41 (17.75%) and Injectable Antimicrobials-40 (17.32%), NSAID's-40 (17.32%.) and Topical Betnovate-36 (15.58%.). Regarding the type, 95 cases were of maculopapular rashes (41.12%), steroid damaged face in 42 (18.18%) andacute urticaria in 20 (8.65%). In terms of Severity assessment, authors found 23 cases (9.95%) as Mild, 176 cases (76.19%) of moderate severity and 32 cases (13.85%) of Severe category. In terms of causality assessment: 3 cases as Certain, 68 cases as Probable and 160 cases as Possible.Conclusions: From this study, it was found maximum Dermatological ADRs of moderate severity and few cases of causality category as “Certain”.

Mature Cystic Teratoma of Ovary– a Case Report & Review of Literature

2020 ◽  
Author(s):  
Sunita Nayak ◽  
Suren Prasad Dash
Keyword(s):  
Case Report ◽  
Germ Cell ◽  
Ovarian Neoplasms ◽  
Germ Cell Tumour ◽  
Cystic Teratoma ◽  
Good Prognosis ◽  
Mature Cystic Teratoma ◽  
Review Of Literature ◽  
The Right

Abstract Mature cystic teratoma or dermoid cyst is the most common germ cell tumour of the ovary. The incidence ranges from 5 to 25% of all ovarian neoplasms out of which 13.7% are bilateral. Teratomas usually occur in the ovaries but they may be seen in other sites known as extragonadal teratomas the incidence of which is only 0.4%. Teratomas are usually benign but they may turn out to be highly malignant. Torsion is known to be the most frequent complication of ovarian teratomas followed by autoamputation. Teratomas are classified as “Mature” and “Immature” by WHO. Teratomas show good prognosis specially the mature ones. Surgery and follow up remains the standard approach. We report a case of mature cystic teratoma in the right ovary of a 28 years old nulliparous woman.

scholarly journals A Case Report of Mature Cystic Teratoma in a post-menopausal Woman, a Rare Entity.

2021 ◽  
Vol 5 (2) ◽  
pp. 891-895
Author(s):  
Ahmed Hassan Abdelmoneim ◽  
Abdelwahed Abougazia ◽  
Amal Said Mahan ◽  
Amal Alobadli ◽  
Adham Darweesh
Keyword(s):  
Cystic Teratoma ◽  
Reproductive Age ◽  
Ca 125 ◽  
Menopausal Woman ◽  
Age Group ◽  
Ovarian Tumours ◽  
Benign Tumours ◽  
Post Menopausal ◽  
Level Monitoring ◽  
Reproductive Age Group

Ovarian tumours are commonly seen in reproductive age group in women. However, when they occur at extremes of age, the suspicion of malignancy increases. The detection of dermoid cyst at 56 years of age is uncommon, hence proper imaging with CA-125 level monitoring is essential. Awareness of benign tumours or rare possibility of malignant transformation in such age is mandatory for surveillance management or planning the surgical procedure.

scholarly journals Ovarian Neoplasms: Clinicopathological Spectrum in Tribal Rajasthan, India

2021 ◽  
Author(s):  
Geeta Mukhiya ◽  
Nalini Sharma ◽  
Kruti Arvindkumar Savalia
Keyword(s):  
Germ Cell ◽  
Ovarian Neoplasms ◽  
Tertiary Care ◽  
Germ Cell Tumour ◽  
Cancer Registries ◽  
Ovarian Neoplasm ◽  
Cell Tumour ◽  
Metastatic Tumour ◽  
Tertiary Care Centre ◽  
Morphological Pattern

Introduction: Ovarian neoplasms have increased in incidence in leading sites of cancer in five old population based cancer registries on comparing first ten and last ten years data. All three germ layers are afflicted in process of ovarian neoplasm- ceolomic epithelium, germ cell and sex chord/stromal cells. Due to this, ovarian masses are spread widely over all age groups. However, a correct pathological diagnosis goes a long way in management of the disease and consequent benefit to patient. Aim: To assess the histopathological pattern, age, laterality and distribution of ovarian tumours in a tertiary care centre of tribal part of Rajasthan. Materials and Methods: Retrospective hospital based study wherein 157 ovarian specimens received in Department of Pathology of Geetanjali Medical College and Hospital, Udaipur, Rajasthan over a period of three years were studied after obtaining permission from ethical committee. Details such as age, signs and symptoms, laterality were retrieved from patient file. Only benign, borderline or malignant ovarian neoplasm specimens removed surgically were included. Physiological cysts were excluded. Descriptive statistics were used and results were expressed as percentages. Results: Out of 157 ovarian neoplasms, 42 (26.75%) were from hysterectomy specimen, 44 (28.03%) from planned cystectomy for mass, 71 (45.22%) from cytoreductive surgery or tissue obtained from Exploratory Laparotomy. A 63.06%, 33.76% and 3.18% of neoplasms were benign, malignant and borderline, respectively. Extremes of age lied between 14 to 84 years. Mean age for benign, malignant and borderline tumours respectively was 38.60 years (SD=15.21), 47.79 years (SD=14.53) and 38.4 years (SD=14.04), respectively. Unilateral tumours were clearly in abundance with 85.35%. Right-sided tumours were more (49.04%). Surface Epithelial Tumours (SET’s), Germ Cell Tumour (GCT’s) and Sex Chord Stromal Tumours (SCSCT’s) were 59.24%, 34.39% and 6.37%, respectively. Out of 10 cases, 60% were malignant (Granulosa cell tumour). No metastatic tumour was seen during the study period. Conclusion: To effectively reverse the trend in a developing country like India each and every gynaecologist should be aware and well versed with histo-morphological pattern of ovarian neoplasms specific to a region.

scholarly journals Histological Patterns of Ovarian Neoplasms – A Five Year Experience in North-East India

2018 ◽  
Vol 7 (1) ◽  
pp. 1576
Author(s):  
Saha Manasi ◽  
Banerjee Alpana ◽  
Datta Abhijit
Keyword(s):  
Ovarian Neoplasms ◽  
Age Distribution ◽  
Female Genital Tract ◽  
Mucinous Cystadenoma ◽  
Malignant Neoplasm ◽  
Cystic Teratoma ◽  
Ovarian Tumors ◽  
Mucinous Cystadenocarcinoma ◽  
Malignant Neoplasms ◽  
Epithelial Tumors

<p><strong>Background:</strong> Ovary is one of the common sites of neoplasm in females. They manifest in wide spectrum of clinical, morphological and histological features. Ovary is the second most common site of primary malignancy in female genital tract.</p><p><strong>Objectives:</strong> To study the frequency of different histological types of ovarian tumors and to analyze age distribution of these tumors.</p><p><strong>Materials and Methods:</strong> This was a retrospective study of all cases of ovarian tumors received at Pathology Department of Agartala Government Medical College during the period of 5 years from January 2012 to December 2016.</p><p><strong>Results:</strong> A total number of 242 cases were studied. Among these 189 cases (78.1%) were benign, 12 cases (4.96%) were borderline and 41 cases (16.94%) were malignant. Benign neoplasms were most commonly seen between 3<sup>rd</sup> and 5<sup>th</sup> decade of age whereas malignant neoplasms after 4<sup>th</sup> decade. Serous cystadenoma was the commonest benign tumor followed by mucinous cystadenoma and mature cystic teratoma. Among the malignant surface epithelial tumors, mucinous cystadenocarcinoma was most common, followed by serous cystadenocarcinoma.</p><p><strong>Conclusion:</strong> Benign ovarian neoplasms outnumber the malignant ones in all age groups. Surface epithelial tumors are the most common class of tumors and mucinous cystadenocarcinoma is the commonest malignant neoplasm.</p>

scholarly journals Spectrum of Childhood and Adolescent Ovarian Tumors in India: 25 Years Experience at a Single Institution

2016 ◽  
Vol 4 (4) ◽  
pp. 551-555 ◽  
Author(s):  
Ruchi Rathore ◽  
Sonal Sharma ◽  
Deepshikha Arora
Keyword(s):  
Adolescent Girls ◽  
Tertiary Care ◽  
Cystic Teratoma ◽  
Common Type ◽  
Mature Cystic Teratoma ◽  
Benign Tumour ◽  
Age Group ◽  
Adnexal Masses ◽  
Childhood Malignancies ◽  
Ovarian Tumours

BACKGROUND: Ovarian tumour in children and adolescent girls form an uncommon but important part of gynaecological malignancies. They account for 1% of all the childhood malignancies and 8% of all abdominal tumours in children. Since the ovarian cysts are thought to arise from mature follicles, these tumours were considered to be infrequent in the paediatric population.AIM: The rarity of this condition prompted us to conduct this study and share our experience on the incidence and clinicopathological features of different ovarian tumours in girls up to 20 years of age observed in last 25 years at a single tertiary care hospital.MATERIAL AND METHODS: This was a retrospective study conducted in the Department of Pathology at a tertiary hospital, Delhi. All ovarian tumours up to the age of 20 years in the past 25 years (1990-2014) were included for the purpose of studying the clinicopathological aspects of ovarian tumours in this age group. Descriptive statistics for prevalence and age-wise prevalence was done. Chi-square test, to find an association between the age, laterality and size with malignancy was performed.RESULTS: We received a total of 1102 cases of ovarian tumours over the period of 25 years  (1990 to 2014), of which 112 (10%) cases were seen in girls up to 20 years of age. The mean age of the patients was 15.3 ± 4 years. The most common presenting complaint was pain abdomen (46.4 %) There was a statistically significant correlation found between size and malignancy status of tumours in our study (p = 0.00). Of 112 cases of ovarian tumours, 39/112 (34.8%) were malignant and 73/112 (65.2%) were benign. Mature  cystic teratoma (27.6%) was the most common type of benign tumour in this age group and immature teratomas were the most common type of malignant ovarian neoplasms.CONCLUSION: Premenarchal girls with ovarian masses may have varied presentations. Abdominal pain is the most common presenting complaint of young adolescent girls with adnexal masses. So the index of suspicion should be kept high and prompt investigations like ultrasound must be performed early to rule out such adnexal masses. Immature Teratoma was the most common malignant and mature cystic teratoma was the most common benign tumour in our study.

Incidence of Cerebral Hemorrhage in Traumatic Patients using Computed Tomography in Tabuk City, Saudi Arabia

2020 ◽  
Vol 5 (10) ◽  
pp. 460-463
Author(s):  
Amna Mohamed Ahmed ◽  
Towmader Awad ◽  
Hajer Yousif ◽  
Reem Nahari ◽  
Omnia Abdelrhman ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Saudi Arabia ◽  
Head Trauma ◽  
Subdural Hematoma ◽  
Cerebral Hemorrhage ◽  
Imaging Modality ◽  
Common Type ◽  
Radiology Department ◽  
Age Group ◽  
Ct Finding

Computed Tomography (CT) is the most commonly used imaging modality in the evaluation of cerebral hemorrhage in the head trauma patients. Objective: To study the incidence of a cerebral hemorrhage in traumatic patients using computed tomography. Method: This retrospective study was conducted at King Khalid hospital in Tabuk city, Saudi Arabia, in the radiology department, in the period from September 2018 to April 2020. The study was done by collecting 471 CT reports of patients all of them were exposed to head trauma with deferent reasons. The data were analyzed by Statistical Package for the Social Sciences (SPSS) program (ver. 20) and presented in tables and graphs according to the checklist which includes: patient age, gender, type of trauma, CT finding, and type of hemorrhage. Results: The most age group suffered from head trauma was less than 20 years percentage (55%), The male patients more exposed to head trauma than female patients with percentage (84.5%), the road traffic accident (RTA) is the most common type of trauma by percentage (63.5%), according to the CT finding; the cerebral hemorrhage represented (15.5%) with the highest percentage in a subdural hematoma (31.2%), the fracture represented (2.8%) while the normal appearance represented (81.7%) as the highest percentage. Conclusion: Most of the traumatic brain injury in patients caused cerebral hemorrhage and the CT scan reports show that: the common type of cerebral hemorrhage is subdural hematoma and it is common in males which exposed to (RTA) in the age group (21 - 40) years old.

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