scholarly journals Effect of Dietary Phosphorus and Zinc Levels on Hematocrit Value, Plasma Mineral Content and Plasma Alkaline Phosphatase Activity of Fingerling Rainbow Trout, Oncorhynchus mykiss

2013 ◽  
Vol 20 (1-2) ◽  
pp. 183-192 ◽  
Author(s):  
MSA Sarker ◽  
S Satoh
Keyword(s):  
Alkaline Phosphatase ◽  
Rainbow Trout ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Zinc Supplementation ◽  
Plasma Zinc ◽  
Dietary Phosphorus ◽  
Significant Difference ◽  
Plasma Alkaline Phosphatase ◽  
Zinc Levels

A laboratory based 2 × 2 factorial experiment was conducted to investigate the effects of dietary phosphorus and zinc levels on hematocrit value, plasma alkaline phosphatase activity and plasma mineral contents of rainbow trout fingerling for 21 weeks. Two levels of phosphorus (19 and 30 mg/g) and two levels of zinc (55 and 100 µg/g) in the dry diets were tested. Duplicate tanks of 30 rainbow trout (average weight 1.56 ± 0.24g) per 60L glass tank were fed experimental diets three times a day to satiation level in 15 to 24oC water temperature. Zinc supplementation in the practical diets significantly increased the hematocrit value, plasma alkaline phosphatase activity and plasma zinc contents in rainbow trout fingerling. On the other hand, addition of phosphorus did not show any significant difference among the treatments. The result of the present study demonstrated that additional zinc significantly (P<0.05) influenced the hematocrit value, plasma alkaline phosphatase activity and plasma zinc contents in rainbow trout. Hence, it can be concluded that zinc supplementation is necessary in fingerling rainbow trout feed. Further studies in this area with different size and age of rainbow trout are needed broadly.DOI: http://dx.doi.org/10.3329/pa.v20i1-2.16870 Progress. Agric. 20(1 & 2): 183 – 192, 2009

scholarly journals Influence of Dietary Phosphorus and Zinc Levels on Whole Body Mineral, Liver Mineral, and Liver Vitamin-C Contents of Fingerling Rainbow Trout, Oncorhynchus mykiss

1970 ◽  
pp. 135-142
Author(s):  
MS Alam Sarker ◽  
Shuichi Satoh
Keyword(s):  
Rainbow Trout ◽  
Vitamin C ◽  
Zinc Supplementation ◽  
Whole Body ◽  
Average Weight ◽  
Liver Copper ◽  
Dietary Phosphorus ◽  
Significant Difference ◽  
Zinc Levels ◽  
Liver Vitamin

A laboratory based 2 × 2 factorial experiment was conducted to investigate the influence of dietary phosphorus and zinc levels on whole body mineral, liver mineral, and liver vitamin-C contents of fingerling rainbow trout for 21 weeks. Two levels of phosphorus (19 and 30 mg g-1) and two levels of zinc (55 and 100 μ g g-1) in the dry diets were tested. Duplicate tanks of 30 rainbow trout (average weight 1.56 ± 0.24 g) per 60L glass tank were fed experimental diets three times a day to satiation level in 15 to 24oC water temperature. The result of the present study demonstrated that dietary zinc supplementation significantly influenced the whole body zinc and liver copper contents in fingerling rainbow trout where as additional phosphorus did not show any significant difference. Zinc supplementation significantly influenced the liver vitamin-C contents of the fish. Hence it is clear that zinc supplementation is necessary in fingerling rainbow trout feed. Further studies in this area are needed broadly. Key words: Phosphorus, zinc, whole body, liver mineral, liver vitamin-C, rainbow trout DOI = 10.3329/jard.v5i1.1470 J Agric Rural Dev 5(1&2), 135-142, June 2007

scholarly journals Role and effects of zinc supplementation in HIV-infected patients with immunovirological discordance: A randomized, double blind, case control study

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0244823
Author(s):  
Macarena Silva ◽  
Carmen G. Montes ◽  
Andrea Canals ◽  
Maria J. Mackenna ◽  
Marcelo Wolff
Keyword(s):  
Zinc Supplementation ◽  
Group Versus ◽  
Cd4 Count ◽  
Control Group ◽  
Immune Recovery ◽  
Plasma Zinc ◽  
Absolute Increase ◽  
Number Of Patients ◽  
Significant Difference ◽  
Zinc Levels

Introduction It has been estimated that between 15% and 18% of patients who start antiretroviral therapy (ART) do not achieve a successful immune recovery despite complete virological suppression. In the literature this phenomenom is known as poor immune recovery or immunovirological discordance (IVD). Zinc has an immunomodulatory role associated with T lymphocytes and its supplementation could enhance immune recovery. Objective To determine if zinc supplementation on IVD patients prevents immune failure after 12 months of supplementation. Secondary objectives were to determine serum zinc levels in HIV patients with and without IVD and the frequency of hypozincemia in discordant patients. Method We reviewed the historical record of patients under care at Arriarán Foundation. Following inclusion criteria were defined: 1) age ≥ 18 years, 2) standard ART (three effective drugs) for at least 18 months, 3) virologically suppressed for 12 months, 3) persistence of CD4 count ≤200 cells/mm3 and/or increase ≤ 80 cells/mm3 after one year of viral undetectability. A control group was assigned paired 1:1 by sex, age (± 2 years) that did achieved an increase of CD4> 350 cells/ mm3. In both groups plasma zinc levels were determined. In a later phase, patients with IVD were randomized to receive zinc (15 mg daily) versus placebo. Patients were followed for 12 months with CD4 count, viral load and zinc levels determinations every 4–6 months. Results A total of 80 patients, 40 patients with IVD criteria and 40 controls were included. 92.5% were men, and age average was 47.5 years. The median baseline CD4 was 189 cells/mm3 (71–258) in the cases vs. 552.5 cells/ mm3 (317–400) in the control group with a median increase at the end of the study of 39 cell/mm3 and 19 cell/mm3 respectively. There was no difference in baseline plasma zinc levels between both groups (81.7 + 18.1 in cases versus 86.2 + 11.0 in controls). In the 40 patients with IVD, the median absolute increase in CD4 after annual zinc supplementation was 31.5 cells/mm3 in the treated group versus 50 cells/mm3 in the placebo group, this difference being statistically not significant (p = 0.382). Conclusions Patients with IVD have plasma zinc levels similar to those who achieve adequate immune recovery. Zinc supplementation in IVD patients showed a statistically non-significant difference in in CD4 levels between cases and controls. The results warrant a comparative study with a larger number of patients.

RICKETS, DEFICIENCY OF "ALKALINE" PHOSPHATASE ACTIVITY AND PREMATURE LOSS OF TEETH IN CHILDHOOD

PEDIATRICS ◽  
1953 ◽  
Vol 11 (4) ◽  
pp. 309-322
Author(s):  
EDNA H. SOBEL ◽  
LELAND C. CLARK ◽  
R. PHYLLIS FOX ◽  
MEINHARD ROBINOW
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Enzyme Treatment ◽  
Deciduous Teeth ◽  
Local Factor ◽  
Plasma Alkaline Phosphatase ◽  
Serum Inorganic Phosphate ◽  
Genetically Determined

A child, studied between the ages of 1½ and 3½ years, presented an abnormally low plasma alkaline phosphatase activity (0.8-1.64 Bessey-Lowry u.), a deformed skeleton and the loss of most of her deciduous teeth. The serum Ca was normal; the serum inorganic phosphate remained at the normal relatively high levels of infancy as the child grew older Roentgenograms demonstrated deficient mineralization of the skeleton and teeth. Biopsies of the liver and the costochondral junction displayed a deficiency of tissue alkaline phosphatase activity. The architecture of the rib was consistent with rickets. There was no evidence for the presence of an inhibitor of alkaline phosphatase, such as beryllium, or for an excessive excretion of the enzyme. Treatment with purified growth hormone, ascorbic acid and thiamin chloride had no effect, while vitamin D 500 thousand u. caused little change in the enzyme activity in a 10 day period. The father had low plasma alkaline phosphatase activity and a number of similar patients are mentioned, for whom there was also evidence that the deficiency in alkaline phosphatase activity may be genetically determined. While the precise role of alkaline phosphatase activity in the metabolism of bone is not clear, the findings in this patient suggest that growing bone may require the presence of alkaline phosphatase for normal calcification, and that the skeletal disorder, which could not be distinguished from rickets, may be related to a disturbance in the local factor.

scholarly journals Effect of starvation and sampling time on plasma alkaline phosphatase activity and calcium homeostasis in the rat

1989 ◽  
Vol 23 (1) ◽  
pp. 53-58 ◽  
Author(s):  
C. S. Thompson ◽  
D. P. Mikhailidis ◽  
D. S. Gill ◽  
J. Y. Jeremy ◽  
J. L. Bell ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Whole Blood ◽  
Calcium Concentration ◽  
Sampling Time ◽  
Ionized Calcium ◽  
Plasma Calcium Concentration ◽  
Plasma Alkaline Phosphatase ◽  
25 Oh Vitamin D

The effect of starvation and sampling time on plasma alkaline phosphatase activity, total plasma calcium concentration and whole blood ionized calcium concentration was determined in the rat. Starvation caused a significant fall in total and ionized calcium concentrations as well as in alkaline phosphatase activity. These changes were accompanied by a fall in whole blood pH and an increase in the anion gap and a decrease in urinary excretion of calcium. These indices were restored to normal following refeeding. There was no change in serum 25-OH vitamin D concentrations following starvation for 3 days. Alkaline phosphatase activity showed a pattern compatible with the presence of a circadian rhythm when sampling took place between 0800 and 1800 h. Total and ionized calcium concentrations did not show such a rhythm when animals were fed the present diet.

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