scholarly journals Adverse Donor Reaction During and Immediately After Venesection

1970 ◽  
Vol 20 (1) ◽  
pp. 39-47
Author(s):  
M Mahbub-ul-Alam ◽  
M Shamim Hyder ◽  
MB Karim Khan ◽  
M Answarul Islam

There are no reports in the transfusion medicine literature that describe adverse donor reactions after whole-blood donation based on solicited information. A descriptive study was done in the Transfusion Medicine Department, Dhaka Medical College Hospital during the period of July 2000 to December 2001. The present study solicited adverse donor reaction and donor reaction information from 14,413 randomly selected whole-blood donors approximately immediately or within 30 minutes after the whole-blood donation. From this study, percentage of adverse donor reaction was 4.98%. The number of prior donations was inversely proportional to the risk of reaction; It was found that, first-time donors have a higher frequency of reactions (5.04%) than do repeat donors (4.96%).The value for first-time or repeated donor were significant (p<0.0001).Female donors are more vulnerable to adverse donor reaction than male donors (5.97%) (4.94%) (p<0.001). In this study it was also found that, fainting or vasovagal attack was more common in female donors (0.77 %) than male donors (0.35 %). It was also found incidence were more in first time donor (1.08%) than repeated donor (0.0%) in case of female donor. Adverse donor reaction after donation and complaints may be more common than previously thought. The post donation follow-up and interview is a good tool for defining the blood donor's experience. It can also be used to evaluate and potentially improve blood donor safety and comfort.   doi: 10.3329/taj.v20i1.3088 TAJ 2007; 20(1): 39-47

2013 ◽  
Vol 22 (2) ◽  
pp. 47-50
Author(s):  
FS Chowdhury ◽  
MAE Siddiqui ◽  
KGM Rahman ◽  
HA Begum ◽  
HA Begum ◽  
...  

Introduction: Without blood there may be no blood transfusion. Without donors there may not any blood. During vasovagal reaction there is chance of accidental fall and injury to blood donor. So improving the safety of the blood donation experience will reduce the donor injuries and increase the blood donation, donation frequency and donor satisfaction. Objective: This study was done to find out the incidence of blood donor reaction- vasovagal reactions among the blood donors attending at transfusion medicine department of Dhaka Medical College Hospital and to improve the donor’s safety. Methodology: This study was done at Transfusion Medicine Department of Dhaka Medical College Hospital in the period between January 2010 to December 2010. Total 21815 donors of 18 to 55 years of both sexes were selected after reviewing the questionnaire, physical and medical examination and written consent. Donors were observed for 30 minutes after donation. The needle site was covered with a bandage and the donor was directed to keep the bandage on for several hours. Result: In this study, out of 21815 donors 163(8.7%) developed reaction. In163 reactions, 72(44.18%) were in male and 91 (55.82%) were in female donors. Within 20179 male donors, adverse reactions occurred in 72 (0.35%) and within 1636 female donors, adverse reactions occurred in 91 (5.56%) The symptoms were agitation 23 (14.12%), pallor 31 (19.02%), sweating 29 (17.79%), nausea 21 (12.88%), vomiting 38 (23.21%), cold feeling 12(7.36%), loss of consciousness 9(5.52%),i.e. severe reactions were 9(5.53%) and mild to moderate reactions were154 (94.47%). Among the reactions 127 (0.89%) occurred in new donors, 32 (0.49%) occurred in occasional donors and 4 (0.37%) in periodic donors. Conclusion: Vasovagal reactions are more common in female and new donors. DOI: http://dx.doi.org/10.3329/bjmed.v22i2.13589 Bangladesh J Medicine 2011; 22: 47-50


2021 ◽  
Vol 28 (2) ◽  
pp. 179-183
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Kashfia Islam ◽  
ABM Al Mamun

Background: The platelet transfusions help in prevention of bleeding related complications and thus prevents morbidity and mortality in thrombocytopenic patients. Platelet transfusion plays an important role in the treatment of haematological, oncological, surgical, and transplant patients. Platelets are transfused by two methods i) by fractionation of whole blood and ii) by platelet apheresis. Over the last decade there has been a trend towards the use of SDPs rather than pooled random donor platelets in thrombocytopenic patients. Optimization of platelet yield is an emerging issue to identify factors which may help in selecting donors to obtain higher platelet yields in shorter time and consequently better clinical outcome. Objective: The quality of single donor platelets (SDP) in terms of yield influences the platelet recovery in the recipient. The aim was to identify the SDP donor factors that influence platelet yield. Methods: The study was undertaken at transfusion medicine department, DMCH from 1st January 2017 to 31st December 2017. The study included 350 plateletpheresis procedures. All procedures were performed according to manufacturer’s manual and standard operating procedure. Results: During the period of study, 350 platelet pheresis donors were studied. All of the donors were male. Platelet yield showed high statistical significance with pre donation platelet count and its indices. (p=0.000). Statistical significant negative correlation was seen between pre donation Hb concentration and the platelet yield. (p =0.005). No statistical significance was seen height (p=0.933), weight (p=0.760) of donor on platelet yield. Conclusion: Platelet recovery in the patient is influenced by the transfused dose of platelets, which in turn is dependent on the quality of the platelet product in terms of yield. Various donor factors such as pre donation platelet count and haemoglobin concentration may affect platelet yield. J Dhaka Medical College, Vol. 28, No.2, October, 2019, Page 179-183


Author(s):  
Mohammad Rafiqul Islam ◽  
Khondaker Abul Bashar ◽  
Shariful Matin ◽  
Tahmid Tanveer ◽  
Atiqur Rahman ◽  
...  

Introduction: On 11th March, 2020 COVID19 was declared as a pandemic and it currently involves 210 countries worldwide. Bangladesh declared its first case on 8th March 2020. Currently, the highest case detection of COVID is in the Dhaka district. Due to a lack of quality PPE (personal protection equipment) and proper knowledge of donning, doffing and transmission dynamics of COVID 19 thought to be high infection rate among physicians. Material and Methods: A pretested questionnaire was set and distributed among COVID 19 infected physicians working at Shaheed Suhrawardy Medical College Hospital through internet to know about the clinical and epidemiological characteristics. Results: 65.3% of the respondents were male and had a mean age were 35.7 years. Among all the respondents, the highest number of physicians involved were from medicine department (26.9%). Lethargy, body ache and fever were observed in 57.69%, 50% and 30.7% patients respectively. Among 52 infected physicians, first time RT-PCR for COVID 19 yield 78.8% positive results. Prophylactic dose of hydroxychloroquine taken by 15.3% patients before being infected with COVID19. Conclusion: Health care workers are getting infected in a alarming number but fortunately at Shaheed Suhrawardy Medical college all the cases were in mild form. J Bangladesh Coll Phys Surg 2020; 38(0): 56-60


1970 ◽  
Vol 17 (1) ◽  
pp. 38-40
Author(s):  
MM Hossain ◽  
SFM Khyirul Ataturk ◽  
ARM Saifuddin Ekram ◽  
M Abul Kalam

About fifty two thousand admitted patients in different wards & cabins of Rajshahi Medical College Hospital are grouped in the Transfusion Medicine Department for the purpose of blood transfusion during the period of July/ 1997 to June/2000. It is found that out of 51966 patients, 16928 (32.38%) are group B, 16704(32.15%) are group O 13005 (25.02%) are group A, & 5329 (10.25%) are group AB, Among those patients, 50141 (96.51%) are Rh D positive, 1828(3.49%) are negative.   doi: 10.3329/taj.v17i1.3488 TAJ 2004; 17(1) : 38-40


2013 ◽  
Vol 21 (1) ◽  
pp. 37-40
Author(s):  
FS Chowdhury ◽  
HA Begum ◽  
HA Begum ◽  
Z Nazreen ◽  
MAE Siddiqui ◽  
...  

DOI: http://dx.doi.org/10.3329/jdmc.v21i1.13236 J. Dhaka Med. Coll. 2012; 21(1): 37-40


2016 ◽  
Vol 24 (1) ◽  
pp. 53-56
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Hussne Ara Begum ◽  
Syeda Masooma Rahman ◽  
...  

Objective: This study was aimed to identify the distribution patterns of ABO and Rh-D blood group among the blood donor attending at transfusion medicine department DMCHin order to promote social awareness and safe blood transfusion among the population.Method: It was a cross sectional study conducted in the Department of Transfusion Medicine, Dhaka Medical College Hospital, Dhaka, from January to December 2014. After proper ethical consideration, a total of 39,512 blood donors were included in this study. They were selected irrespective of age and sex by systematic random sampling. ABO and Rh-D blood groups were determined by the antigen antibody agglutination test in our blood bank by standard tile techniques.Results: Among 39,512 blood donors male blood donors were 31,602(79.98%), female blood donors were 7,910(20.01%).14,817(37.5%) blood donor were identified as having blood group B, while 12,565 (31.8%) were blood group O, 8614( 21.80%) and3516( 8.9% )were blood group A and AB respectively. Rh-D positive were 38,247(96.79%) and Rh-D negative were 1,265(3.2%).J Dhaka Medical College, Vol. 24, No.1, April, 2015, Page 53-56


2021 ◽  
Vol 16 (1) ◽  
pp. 8-11
Author(s):  
Md Jahangir Alam ◽  
Md Monir Hossain ◽  
Mohammad Neamat Hossain ◽  
Ahmmed Manadir Hossain ◽  
Lipika Sanjowal

Efficient blood transfusion facility in the casualty wards is essential to minimize the morbidity and mortality of the injured patients. Proper knowledge of blood transfusion demand in a facility can help forecast future demands and facilitate the planning of existing resources allocation for best injury care. This cross-sectional study was conducted at the causality wards of Dhaka Medical College Hospital from July 2018 to December 2018. During this period, patients who attended the casualty wards and needed whole blood transfusion were selected as the study population. Relevant information regarding the required blood units, blood group, and blood collection source were recorded and analyzed. During our study period, 1619 units of whole blood were required by 896 patients. Most of the study population were from the age group of 31-40 years. Male group was the predominant at a 3.9:1 male-female ratio. Majority of the patients (55.13%) required only one unit of blood, and 28.57% of the patients required two units. O+ve blood group was the most demanded (34.65%) followed by B+ve, A+ve, AB+ve, O-ve, B-ve and A-ve (31.87%, 23.72%, 7.6%, 1.42%, 0.49% and 0.25%, respectively). The patients' relatives donated around 85% of blood, and the rest were from voluntary donors. The average daily and weekly requirement of whole blood for the causality departments of Dhaka Medical College Hospital was around 9 and 62 units respectively. Evidence-based expert guideline for the use of whole blood in the casualty management and social awareness for blood donation may save thousands of valuable lives. Faridpur Med. Coll. J. 2021;16(1):8-11


2020 ◽  
Vol 20 (2) ◽  
pp. 61-64
Author(s):  
Mohammad Mahfuzur Rahman Chowdhury ◽  
Rifat Zaman ◽  
Md Amanur Rasul ◽  
Akm Shahadat Hossain ◽  
Shafiqul Alam Chowdhury ◽  
...  

Introduction and objectives: Congenital ureteropelvic junction obstruction (UPJO) is the most common cause of hydronephrosis. Management protocols are based on the presence of symptoms and when the patient is asymptomatic the function of the affected kidney determines the line of treatment. Percutaneous nephrostomy (PCN) became a widely accepted procedure in children in the 1990s. The aim of the study was to evaluate the results of performing percutaneous nephrostomy (PCN) in all patients with UPJO and split renal function (SRF) of less than 10% in the affected kidney, because the management of such cases is still under debate. Methods:This prospective clinical trial was carried out at Dhaka Medical College Hospital from January 2014 to December 2016. Eighteen consecutive patients who underwent PCN for the treatment of unilateral UPJO were evaluated prospectively. In these children, ultrasonography was used for puncture and catheter insertion. Local anesthesia with sedation or general anesthesia was used for puncture. Pig tail catheters were employed. The PCN remained in situ for at least 4 weeks, during which patients received low-dose cephalosporin prophylaxis. Repeat renography was done after 4 weeks. When there was no significant improvement in split renal function (10% or greater) and PCN drainage (greater than 200 ml per day) then nephrectomies were performed otherwise pyeloplasties were performed. The patients were followed up after pyeloplasty with renograms at 3 months and 6 months post operatively. Results: All the patients had severe hydronephrosis during diagnosis and 14 patients with unilateral UPJO were improved after PCN drainage and underwent pyeloplasty. The rest four patients that did not show improvement in the SRF and total volume of urine output underwent nephrectomy. In the patients with unilateral UPJO who improved after PCN drainage, the SRF was increased to 26.4% ±8.6% (mean± SD) after four weeks and pyeloplasty was performed. At three and six months follow-up, SRF value was 29.2% ±8.5% and 30.8.2% ±8.8% respectively. Conclusion: Before planning of nephrectomy in poorly functioning kidneys (SRF < 10%) due to congenital UPJO, PCN drainage should be done to asses improvement of renal function. Bangladesh Journal of Urology, Vol. 20, No. 2, July 2017 p.61-64


2020 ◽  
Vol 22 (2) ◽  
pp. 89-94
Author(s):  
Nasir Uddin Mahmud ◽  
ABM Khurshid Alam ◽  
Mohammad Altaf Hossain Chawdhury ◽  
Mohammad Abul Khair

Background : Pilonidal sinus was first described by Dr. A.W. Anderson in 1847 and is often seen in the intergluteal region. It is a disease of mainly younger male and rarely affects after 40. Main causes for the formation of this sinus are hirsutism, sweating in the area, repeated maceration due to trauma, leading to breakage of the skin barrier, attracting hair inside which initiates a foreign body reaction leading to infection with abscess or sinus formation. Most common embarrassing situation is discharging sinus. The diagnosis is mainly on clinical ground. Though there are a lot of modalities of treatment but recurrence is still a challenge. We have adopted Limberg flap technique since 2012 with a least recurrent chance. Objectives : To prove that this procedure will be end up with lower morbidity & least chance of recurrence Methods : This prospective study was done jointly by the Department of Surgery of Central Medical College and Comilla Medical College Hospital. In this series 50 patients were selected from July 2012 to June 2017. Results : Out of 50 patients operated by Limberg flap technique 42(84%) were males and 8(16%) were females. Mean age was 27.3 years (range 18–37years). Of them,12(24%) were driver, 6(12%) police, 6(12%) teacher, 6(12%) student, 5(10%) worker, 4(8%) millitary army, 4(8%) housewife, 4 (8%)service holder, 2(4%) computer operator, 1(2%) doctor and 1(2%) were barber. In our study most common mode of presentation were chronic discharging sinuses 15(30%), beside this 12(24%) had multiple sinuses, 10(20%) had multiple pits,7(14%) had acute abscess and 6(12%) had unpleasant smell. Associated hirsutism were present in 30(60%) and absent in 20(40%) patients. One (2%) male patient had wound gap & discharge and six(12%) patients had flap edema. We have found no recurrence in follow up period. Conclusion : Pilonidal sinus is a notoriously recurrent disease, so treatment by this flap technique is the only hope of cure with lower morbidity. Journal of Surgical Sciences (2018) Vol. 22 (2) : 89-94


2019 ◽  
Vol 6 (2) ◽  
pp. 73-76
Author(s):  
Mohammad Ibrahim Khalil ◽  
Md Ashiqur Rahman ◽  
Adnan Ahmed ◽  
Samia Shihab Uddin ◽  
Mohammad Alauddin ◽  
...  

Background: Haemorroid stapler becomes easier and safe to deal multiple and prolapsed haemorrhoid at a time. Objectives: The purpose of the present study was to evaluate the outcome of suture haemorrhoidopexy for secondary position haemorrhoids in addition to haemorrhoidectomy for primary haemorrhoids (multiple). Methodology: This prospective interventional study was performed in Dhaka Medical College Hospital, Dhaka, Bangladesh and in a private hospital in Gazipur, Bangladesh for over five (05) years from January 2012 to December 2016. Patients who were presented with secondary position haemorrhoids in addition to primary position haemorrhoids (multiple haemorrhoids) were included in this study. Open haemorrhoidectomy (Milligan-Morgan) followed by suture haemorrhoidopexy was done. All patients were followed up after 1, 2, 4, 8 weeks, 6 months and 1 yearly. Result: Total 18 patients were operated. Among those immediate complications were encountered in patients in the form of per rectal bleeding 1(5.55%), pain 3(visual pain scale 4)16.66%, mucosal oedema 6(33.33%), no patient developed early postoperative prolapse. No patient developed bowel incontinence. Late complications experienced as prolapse at 1 year follow up which was treated by conservative measures. No patient developed anal stenosis. Mean operating time was 25 minutes and duration of hospital stay was 1 day. Conclusion: Stapled haemorrhoidopexy is a safe procedure for circumferential excision of mucosa and submucosa dealing all haemorrhoids and prolapse simultaneously. Journal of Current and Advance Medical Research 2019;6(2): 73-76


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