Effect of Donor Variables on Platelet Yield Among Donor Undergoing Plateletpheresis at Transfusion Medicine Department, Dhaka Medical College Hospital (Experience of 350 Procedures)

2021 ◽  
Vol 28 (2) ◽  
pp. 179-183
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Kashfia Islam ◽  
ABM Al Mamun
Keyword(s):  
Platelet Count ◽  
Statistical Significance ◽  
Haemoglobin Concentration ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Platelet Recovery ◽  
Medicine Department ◽  
Medical College ◽  
Donor Factors

Background: The platelet transfusions help in prevention of bleeding related complications and thus prevents morbidity and mortality in thrombocytopenic patients. Platelet transfusion plays an important role in the treatment of haematological, oncological, surgical, and transplant patients. Platelets are transfused by two methods i) by fractionation of whole blood and ii) by platelet apheresis. Over the last decade there has been a trend towards the use of SDPs rather than pooled random donor platelets in thrombocytopenic patients. Optimization of platelet yield is an emerging issue to identify factors which may help in selecting donors to obtain higher platelet yields in shorter time and consequently better clinical outcome. Objective: The quality of single donor platelets (SDP) in terms of yield influences the platelet recovery in the recipient. The aim was to identify the SDP donor factors that influence platelet yield. Methods: The study was undertaken at transfusion medicine department, DMCH from 1st January 2017 to 31st December 2017. The study included 350 plateletpheresis procedures. All procedures were performed according to manufacturer’s manual and standard operating procedure. Results: During the period of study, 350 platelet pheresis donors were studied. All of the donors were male. Platelet yield showed high statistical significance with pre donation platelet count and its indices. (p=0.000). Statistical significant negative correlation was seen between pre donation Hb concentration and the platelet yield. (p =0.005). No statistical significance was seen height (p=0.933), weight (p=0.760) of donor on platelet yield. Conclusion: Platelet recovery in the patient is influenced by the transfused dose of platelets, which in turn is dependent on the quality of the platelet product in terms of yield. Various donor factors such as pre donation platelet count and haemoglobin concentration may affect platelet yield. J Dhaka Medical College, Vol. 28, No.2, October, 2019, Page 179-183

scholarly journals Study on ABO & Rhesus Blood Groups in Rajshahi Medical College Hospital

1970 ◽  
Vol 17 (1) ◽  
pp. 38-40
Author(s):  
MM Hossain ◽  
SFM Khyirul Ataturk ◽  
ARM Saifuddin Ekram ◽  
M Abul Kalam
Keyword(s):  
Blood Transfusion ◽  
Blood Groups ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
Group A ◽  
Group B

About fifty two thousand admitted patients in different wards & cabins of Rajshahi Medical College Hospital are grouped in the Transfusion Medicine Department for the purpose of blood transfusion during the period of July/ 1997 to June/2000. It is found that out of 51966 patients, 16928 (32.38%) are group B, 16704(32.15%) are group O 13005 (25.02%) are group A, & 5329 (10.25%) are group AB, Among those patients, 50141 (96.51%) are Rh D positive, 1828(3.49%) are negative.   doi: 10.3329/taj.v17i1.3488 TAJ 2004; 17(1) : 38-40

scholarly journals Incidence of ABO and Rh D blood group among the people attending in Transfusion Medicine Department of Dhaka Medical College Hospital

2013 ◽  
Vol 21 (1) ◽  
pp. 37-40
Author(s):  
FS Chowdhury ◽  
HA Begum ◽  
HA Begum ◽  
Z Nazreen ◽  
MAE Siddiqui ◽  
...  
Keyword(s):  
Blood Group ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
The People

DOI: http://dx.doi.org/10.3329/jdmc.v21i1.13236 J. Dhaka Med. Coll. 2012; 21(1): 37-40

scholarly journals Adverse Donor Reaction During and Immediately After Venesection

1970 ◽  
Vol 20 (1) ◽  
pp. 39-47
Author(s):  
M Mahbub-ul-Alam ◽  
M Shamim Hyder ◽  
MB Karim Khan ◽  
M Answarul Islam
Keyword(s):  
Whole Blood ◽  
Blood Donation ◽  
Transfusion Medicine ◽  
Good Tool ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
Female Donor ◽  
First Time

There are no reports in the transfusion medicine literature that describe adverse donor reactions after whole-blood donation based on solicited information. A descriptive study was done in the Transfusion Medicine Department, Dhaka Medical College Hospital during the period of July 2000 to December 2001. The present study solicited adverse donor reaction and donor reaction information from 14,413 randomly selected whole-blood donors approximately immediately or within 30 minutes after the whole-blood donation. From this study, percentage of adverse donor reaction was 4.98%. The number of prior donations was inversely proportional to the risk of reaction; It was found that, first-time donors have a higher frequency of reactions (5.04%) than do repeat donors (4.96%).The value for first-time or repeated donor were significant (p<0.0001).Female donors are more vulnerable to adverse donor reaction than male donors (5.97%) (4.94%) (p<0.001). In this study it was also found that, fainting or vasovagal attack was more common in female donors (0.77 %) than male donors (0.35 %). It was also found incidence were more in first time donor (1.08%) than repeated donor (0.0%) in case of female donor. Adverse donor reaction after donation and complaints may be more common than previously thought. The post donation follow-up and interview is a good tool for defining the blood donor's experience. It can also be used to evaluate and potentially improve blood donor safety and comfort.   doi: 10.3329/taj.v20i1.3088 TAJ 2007; 20(1): 39-47

scholarly journals The Distribution of Abo and Rhesus Blood Groups Among Blood Donor Attending Transfusion Medicine Department of Dhaka Medical College Hospital in 2014

2016 ◽  
Vol 24 (1) ◽  
pp. 53-56
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Hussne Ara Begum ◽  
Syeda Masooma Rahman ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Groups ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Cross Sectional ◽  
Medicine Department ◽  
Medical College

Objective: This study was aimed to identify the distribution patterns of ABO and Rh-D blood group among the blood donor attending at transfusion medicine department DMCHin order to promote social awareness and safe blood transfusion among the population.Method: It was a cross sectional study conducted in the Department of Transfusion Medicine, Dhaka Medical College Hospital, Dhaka, from January to December 2014. After proper ethical consideration, a total of 39,512 blood donors were included in this study. They were selected irrespective of age and sex by systematic random sampling. ABO and Rh-D blood groups were determined by the antigen antibody agglutination test in our blood bank by standard tile techniques.Results: Among 39,512 blood donors male blood donors were 31,602(79.98%), female blood donors were 7,910(20.01%).14,817(37.5%) blood donor were identified as having blood group B, while 12,565 (31.8%) were blood group O, 8614( 21.80%) and3516( 8.9% )were blood group A and AB respectively. Rh-D positive were 38,247(96.79%) and Rh-D negative were 1,265(3.2%).J Dhaka Medical College, Vol. 24, No.1, April, 2015, Page 53-56

scholarly journals Clinical Presentation of the Epileptic Patients at People Medical College Hospital, Nawabshah, Pakistan

2021 ◽  
pp. 267-273
Author(s):  
Jeando Khan Daidano ◽  
Haresh Kumar Makheja ◽  
Moti Ram Bhatia ◽  
Waseem Raja Memon ◽  
Anwar Ali Jamali ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Medical College Hospital ◽  
Chi Square ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
Epileptic Patients ◽  
Minimum Age ◽  
The Mean

Objective: study will determine clinical presentation, risk, and type of seizures in epileptic patients.  Methodology: This observational study was conducted in Medicine department People Medical College Hospital (PMCH) Nawabshah from January 2020 to December 2020. 110 patients were included for study after informed permission of the patient or their relative. Male and female were selected. Known epileptic patients were included in the study, patients with false seizures were excluded from the study. Statically analysis was done by software SSPS 22 version. Results: Age ranged 18 to 60 years. All the patients included in the study epilepsy was noted. The mean age of patients was 37.40 SD 8.71 years. The minimum age was 28 years while maximum 60 years. Pearson Chi-Square Value 105.000a  Asymp. Sig. (2-sided) .000, Likelihood Ratio Value 135.012  Asymp. Sig. (2-sided) .000, Linear-by-Linear Association Value 16.297 Asymp. Sig. (2-sided) .000 which were statistically significant. Conclusion: Epilepsy is treatable common neurological disease in Pakistan. quality of life can be improved by Education of the patients and their relatives, without socioeconomically  burden.

scholarly journals Incidence of Vasovagal Reaction among the Blood Donors Attending at Transfusion Medicine Department of Dhaka Medical College Hospital

2013 ◽  
Vol 22 (2) ◽  
pp. 47-50
Author(s):  
FS Chowdhury ◽  
MAE Siddiqui ◽  
KGM Rahman ◽  
HA Begum ◽  
HA Begum ◽  
...  
Keyword(s):  
Blood Donors ◽  
Adverse Reactions ◽  
Blood Donation ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
Vasovagal Reactions ◽  
New Donors

Introduction: Without blood there may be no blood transfusion. Without donors there may not any blood. During vasovagal reaction there is chance of accidental fall and injury to blood donor. So improving the safety of the blood donation experience will reduce the donor injuries and increase the blood donation, donation frequency and donor satisfaction. Objective: This study was done to find out the incidence of blood donor reaction- vasovagal reactions among the blood donors attending at transfusion medicine department of Dhaka Medical College Hospital and to improve the donor’s safety. Methodology: This study was done at Transfusion Medicine Department of Dhaka Medical College Hospital in the period between January 2010 to December 2010. Total 21815 donors of 18 to 55 years of both sexes were selected after reviewing the questionnaire, physical and medical examination and written consent. Donors were observed for 30 minutes after donation. The needle site was covered with a bandage and the donor was directed to keep the bandage on for several hours. Result: In this study, out of 21815 donors 163(8.7%) developed reaction. In163 reactions, 72(44.18%) were in male and 91 (55.82%) were in female donors. Within 20179 male donors, adverse reactions occurred in 72 (0.35%) and within 1636 female donors, adverse reactions occurred in 91 (5.56%) The symptoms were agitation 23 (14.12%), pallor 31 (19.02%), sweating 29 (17.79%), nausea 21 (12.88%), vomiting 38 (23.21%), cold feeling 12(7.36%), loss of consciousness 9(5.52%),i.e. severe reactions were 9(5.53%) and mild to moderate reactions were154 (94.47%). Among the reactions 127 (0.89%) occurred in new donors, 32 (0.49%) occurred in occasional donors and 4 (0.37%) in periodic donors. Conclusion: Vasovagal reactions are more common in female and new donors. DOI: http://dx.doi.org/10.3329/bjmed.v22i2.13589 Bangladesh J Medicine 2011; 22: 47-50

scholarly journals Colchicine in the Treatment of Recurrent Oral Aphthous Ulcer -Open Clinical Trial in Bangladesh

1970 ◽  
Vol 39 (3) ◽  
Author(s):  
A Hassan ◽  
Z Ahmed ◽  
R Ali ◽  
F Ara ◽  
N Ahmed ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Oral Mucosa ◽  
Colchicine Treatment ◽  
Aphthous Ulcer ◽  
College Hospital ◽  
Medical College ◽  
Aphthous Ulceration ◽  
Benign Nature ◽  
Medical University

Background: Recurrent aphthous Ulceration (RAU) is characterized by necrotizing ulcers of the oral mucosa that persist, remit, and recur for variable periods of time. Despite the benign nature of the disease, RAU frequently affects quality of life as a result of long lasting and recurrent episodes of burning pain.Aim and objective: the aim of the study was to determine the efficacy of colchicine in treatment of recurrent oral aphthous ulcer.Methods: A clinical trial was conducted among 30 samples in the department of dermatology and venereology of Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka. Study was performed among those who fulfilled the inclusion criteria. Data was collected from 1st September 2007 to 29th February. 2008 and enrolled data was analyzed by using statistical SPSS win 13.Results: Among 30 patients, 24 (80%) were male and 6(20%) were female. Mean age of the patients was 26.20 (±6.65) years. 26(87.7%) patients found ulcer in oral mucosa and 4(13.3%)in tongue, but previous family history was present in only 20% cases out of 30 patients. All patients experienced a marked decrease in symptoms during colchicine treatment in where; mean aphthae count was 3.27 (±1.05) before treatment and 0.43 (±0.68) during treatment. Pain score also reduced during treatment from 6.80 (±2.12) to 1.13 (±.1.11) which was statistically highly significant.Conclusions: Colchicine may be a promising modality of treatment in the therapeutic armamentarium for RAU.DOI: http://dx.doi.org/10.3329/bmj.v39i3.9948 BMJ 2010; 39(3)

Haemolysis due to active venous drainage during cardiopulmonary bypass: comparison of two different techniques

Perfusion ◽  
2001 ◽  
Vol 16 (4) ◽  
pp. 313-318 ◽  
Author(s):  
Silvia Cirri ◽  
Luca Negri ◽  
Marco Babbini ◽  
Giorgio Latis ◽  
Boutros Khlat ◽  
...  
Keyword(s):  
Platelet Count ◽  
Cardiopulmonary Bypass ◽  
Centrifugal Pump ◽  
Statistical Significance ◽  
Postoperative Bleeding ◽  
Haemoglobin Concentration ◽  
Venous Drainage ◽  
Valvular Surgery ◽  
Group A ◽  
Group B

To facilitate mini-access for cardiac surgery, two different methods of active venous drainage are used: vacuum assisted drainage and centrifugal pump aspiration on the venous line. The aim of this study was to compare the haemolysis produced using these two techniques. From June to December 1999, 50 consecutive patients were operated on using a ministernotomy. All of these patients had valvular surgery for either valve repair or valve replacement (9 MVRepair, 11 MVR, 29 AVR, 1 AVR+MVR). They were randomized into two groups: Group A, 25 patients who underwent surgery where vacuum assisted drainage was used, and Group B, 25 patients where kinetic asssisted venous drainage with centrifugal pump venous aspiration was used. Patient characteristics of both groups were similar for age, gender, body weight, body surface area, height, cardiopulmonary bypass (CPB) time, aortic crossclamp time, priming volume, cardioplegia volume, haemoglobin concentration, haematocrit, serum creatinine, bilirubin, lactate dehydrogenase (LDH), serum glutamic oxaloacetic transaminase (sGOT), serum glutamic pyruvic transaminase (sGPT), aptoglobin, reticulocytes, and platelet count. We checked all these laboratory parameters preoperatively, at the end of CPB, and 2 and 24 h after operation. We also checked haemoglobinuria at these same time points. We assessed blood loss at 6, 12, and 24 h after the operation and calculated total postoperative bleeding. There was a tendency towards a greater increase in LDH, sGOT and sGPT in Group A more than in Group B, but these data did not reach statistical significance. Platelet count was always lower in Group A and aptoglobin increased in Group A more than in Group B. More patients in Group A had haemoglobinuria. These findings indicate that haemolysis is increased more in patients treated with vacuum assisted drainage, when compared to the rise in haemolysis in those treated with centrifugal pump venous drainage. Total bleeding is also greater in Group A.

scholarly journals Sociodemography and Clinical Profile of COVID 19 Positive Physicians at a Tertiary Level Hospital, Dhaka

2020 ◽  
pp. 56-60
Author(s):  
Mohammad Rafiqul Islam ◽  
Khondaker Abul Bashar ◽  
Shariful Matin ◽  
Tahmid Tanveer ◽  
Atiqur Rahman ◽  
...  
Keyword(s):  
College Hospital ◽  
Personal Protection Equipment ◽  
Medicine Department ◽  
Medical College ◽  
First Case ◽  
Care Workers ◽  
High Infection ◽  
Epidemiological Characteristics ◽  
First Time ◽  
Body Ache

Introduction: On 11th March, 2020 COVID19 was declared as a pandemic and it currently involves 210 countries worldwide. Bangladesh declared its first case on 8th March 2020. Currently, the highest case detection of COVID is in the Dhaka district. Due to a lack of quality PPE (personal protection equipment) and proper knowledge of donning, doffing and transmission dynamics of COVID 19 thought to be high infection rate among physicians. Material and Methods: A pretested questionnaire was set and distributed among COVID 19 infected physicians working at Shaheed Suhrawardy Medical College Hospital through internet to know about the clinical and epidemiological characteristics. Results: 65.3% of the respondents were male and had a mean age were 35.7 years. Among all the respondents, the highest number of physicians involved were from medicine department (26.9%). Lethargy, body ache and fever were observed in 57.69%, 50% and 30.7% patients respectively. Among 52 infected physicians, first time RT-PCR for COVID 19 yield 78.8% positive results. Prophylactic dose of hydroxychloroquine taken by 15.3% patients before being infected with COVID19. Conclusion: Health care workers are getting infected in a alarming number but fortunately at Shaheed Suhrawardy Medical college all the cases were in mild form. J Bangladesh Coll Phys Surg 2020; 38(0): 56-60

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