scholarly journals Medicazione a base d’argento nella gestione dell’emergenza cutanea

2021 ◽  
Vol 33 ◽  
pp. 99-101
Author(s):  
Walter Lunardi ◽  
Sonia Bianchi
Keyword(s):  
Infectious Complication ◽  
Treatment Strategies ◽  
Silver Ions ◽  
Complete Recovery ◽  
Drop Out ◽  
Exit Site ◽  
Preventive Efficacy ◽  
Subcutaneous Tunnel ◽  
True Infection

Introduction: Exit-site (ES) and tunnel infections are the main infectious complication in peritoneal dialysis (PD); they also are risk factors for the development of peritonitis, for catheter removal and for dialysis drop-out. Up to now, besides the recommendations of the Guidelines there is no uniformity, nor on the classification, nor on the treatment strategies of the infected ES. Recent experiences are reported with alternative types of dressings that aim to reduce the incidence of ES infection and consequently of the subcutaneous tunnel. Methods: The Tuscan group conducted a retrospective observational study of 10 patients on PD who, showing signs of a suspected but not ascertained infection (negative microbiological culture), such as redness, edema, secretion, scab, had been medicated with silver-ions releasing Exit-Pad Ag. The aim was to evaluate and classify the evolution of ES lesions, in order to confirm the preventive efficacy of the silver-ions releasing dressing compared to the traditional ones. Results: After 4 weeks of treatment with Exit Pad Ag maintained in situ for 72 h, 6 patients no longer had any signs of inflammation. In 2 cases, several weeks of treatment were necessary to achieve a complete recovery, while in 2 other cases the signs of inflammation became negative in less time (2 weeks, 1 week). Conclusions: With the utilization of an alternative dressing such as Exit-Pad Ag on PD patients showing early signs of inflammation, the onset of a true infection can be prevented, with a progressive improvement of the ES.

The retrograde tunnel: a method for the fixation of central venous catheters in the military environment

1991 ◽  
Vol 77 (2) ◽  
pp. 75-77
Author(s):  
R. A. Wheeler ◽  
T. J. W. Spalding ◽  
J. A. Thomas ◽  
G. A. Carss
Keyword(s):  
Central Venous Line ◽  
Central Venous Catheters ◽  
Patient Transfer ◽  
Central Venous ◽  
Medical Facilities ◽  
Subcutaneous Tunnel ◽  
Paediatric Practice ◽  
The Military

AbstractCentral venous catheters (CVCs) are prone to accidental removal during patient transportation. Of the casualties who require transfer between medical facilities, those with CVC in situ require additional vigilance to prevent loss of the CVC, which continues to occur despite various methods of fixation. The fashioning of a subcutaneous tunnel has become an integral part of the placement of central venous catheters. Several methods have been described, but the long-term CVCs in paediatric practice pose special problems, particularly that of the patients continually testing the CVCs fixation. Using a new polyurethane CVC, a retrograde tunnelling technique has been developed which affords immediate and secure fixation. We propose that this CVC, together with the technique of retrograde tunnelling, is the solution to inadvertent central venous line removal during patient transfer.

Effect of Phasic Activation on Endplate Potential in Rat Diaphragm

1999 ◽  
Vol 82 (6) ◽  
pp. 3030-3040 ◽  
Author(s):  
Michelle Moyer ◽  
Erik van Lunteren
Keyword(s):  
Time Course ◽  
Complete Recovery ◽  
Stimulation Frequency ◽  
Drop Out ◽  
Rat Diaphragm ◽  
Continuous Stimulation ◽  
Intermittent Stimulation ◽  
Rate Of Decline ◽  
Phasic Activation

Neuromuscular junction endplate potentials (EPPs) decrease quickly and to a large extent during continuous stimulation. The present study examined the hypothesis that EPP rundown recovers rapidly, thereby substantially preserving neurotransmission during intermittent compared with continuous stimulation. Studies were performed in vitro on rat diaphragm, using μ-conotoxin to allow recording of normal-sized EPPs from intact fibers. During continuous 5- to 100-Hz stimulation, EPP amplitude declined with a biphasic time course. The initial fast rate of decline was modulated substantially by stimulation frequency, whereas the subsequent slow rate of decline was relatively frequency independent. During intermittent 5- to 100-Hz stimulation (duty cycle 0.33), EPP amplitude declined rapidly during each train, but recovered substantially by the onset of the following train. The intra-train declines were substantially greater than the inter-train declines in EPP amplitude. Intra-train reductions in EPP amplitude were stimulation frequency dependent, based on both the total decline and rate constant of EPP decline. In contrast, the degree of recovery from train to train was independent of stimulation frequency, indicating low frequency dependence of inter-train rundown. The substantial recovery of EPP amplitude in between trains resulted in greater cumulative EPP size during intermittent compared with continuous stimulation. During continuous stimulation, EPP drop-out was only seen during 100-Hz stimulation; this was completed mitigated during intermittent stimulation. Miniature EPP size was unaffected by either continuous or intermittent stimulation. The pattern of rapid intra-train rundown and slow inter-train rundown of EPP size during intermittent stimulation is therefore due to rapid changes in the magnitude of neurotransmitter release rather than to axonal block or postsynaptic receptor desensitization. These findings indicate considerable rundown of EPP amplitudes within a stimulus train, with near complete recovery by the onset of the next train. This substantially attenuates the decrement in EPP amplitude during intermittent compared with continuous stimulation, thereby preserving the integrity of neurotransmission during phasic activation.

Silver Ions Release from Antibacterial Chitosan Films Containing in Situ Generated Silver Nanoparticles

2012 ◽  
Vol 61 (1) ◽  
pp. 260-267 ◽  
Author(s):  
Gracia López-Carballo ◽  
Laura Higueras ◽  
Rafael Gavara ◽  
Pilar Hernández-Muñoz
Keyword(s):  
Silver Nanoparticles ◽  
Silver Ions ◽  
Chitosan Films

scholarly journals Enhanced Antibacterial Activity of Silver Doped Titanium Dioxide-Chitosan Composites under Visible Light

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1403 ◽  
Author(s):  
Jie Li ◽  
Bing Xie ◽  
Kai Xia ◽  
Yingchun Li ◽  
Jing Han ◽  
...  
Keyword(s):  
Particle Size ◽  
Antibacterial Activity ◽  
Titanium Dioxide ◽  
Visible Light ◽  
Silver Ions ◽  
Antibacterial Activities ◽  
Nano Tio2 ◽  
Inverse Emulsion ◽  
Potential Applications

Nano titanium dioxide (TiO2) with photocatalytic activity was firstly modified by diethanolamine, and it was then doped with broad spectrum antibacterial silver (Ag) by in situ method. Further, both Ag doped TiO2-chitosan (STC) and TiO2-chitosan (TC) composites were prepared by the inverse emulsion cross-linking reaction. The antibacterial activities of STC composites were studied and their antibacterial mechanisms under visible light were investigated. The results show that in situ doping and inverse emulsion method led to good dispersion of Ag and TiO2 nanoparticles on the cross-linked chitosan microsphere. The STC with regular particle size of 1–10 μm exhibited excellent antibacterial activity against E. coli, P. aeruginosa and S. aureus under visible light. It is believed that STC with particle size of 1–10 μm has large specific surface area to contact with bacterial cell wall. The increased antibacterial activity was attributed to the enhancement of both electron-hole separations at the surface of nano-TiO2 by the silver ions under the visible light, and the synergetic and sustained release of strong oxidizing hydroxyl radicals of nano-TiO2, together with silver ions against bacteria. Thus, STC composites have great potential applications as antibacterial agents in the water treatment field.

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