Assessment of Posterior Capsular Opacification of Korean Using Straylight and Glare Sensitivity Meter

2015 ◽  
Vol 56 (7) ◽  
pp. 998 ◽  
Author(s):  
Seung Yong Choi ◽  
Yu Li Park ◽  
Hyun Seung Kim
Biomolecules ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1150
Author(s):  
Dixa Gautam ◽  
Michelle G. Pedler ◽  
Devatha P. Nair ◽  
Jonathan Mark Petrash

Cataracts are a leading cause of blindness worldwide. Surgical removal of cataracts is a safe and effective procedure to restore vision. However, a large number of patients later develop vision loss due to regrowth of lens cells and subsequent degradation of the visual axis leading to visual disability. This postsurgical complication, known as posterior capsular opacification (PCO), occurs in up to 30% of cataract patients and has no clinically proven pharmacological means of prevention. Despite the availability of many compounds capable of preventing early steps in PCO development, there is currently no effective means to deliver such therapies into the eye for a suitable duration. To model a solution to this unmet medical need, we fabricated acrylic substrates as intraocular lens (IOL) mimics scaled to place into the capsular bag of the mouse lens following a mock-cataract surgery. Substrates were coated with a hydrophilic crosslinked acrylate nanogel designed to elute Sorbinil, an aldose reductase inhibitor previously shown to suppress PCO. Insertion of the Sorbinil-eluting device into the lens capsule at the time of cataract surgery resulted in substantial prevention of cellular changes associated with PCO development. This model demonstrates that a cataract inhibitor can be delivered into the postsurgical lens capsule at therapeutic levels.


Nanomedicine ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. 1415-1428 ◽  
Author(s):  
Rajdeep Guha ◽  
Sushovan Chowdhury ◽  
Himangshu Palui ◽  
Akhilesh Mishra ◽  
Samar Basak ◽  
...  

2003 ◽  
Vol 86 (3) ◽  
pp. 157-172 ◽  
Author(s):  
Mark A. Babizhayev ◽  
Anatoly I. Deyev ◽  
Valentina N. Yermakova ◽  
Nina G. Davydova ◽  
Natarya I. Kurysheva ◽  
...  

2007 ◽  
Vol 22 (3) ◽  
pp. 502 ◽  
Author(s):  
Hyeon Il Lee ◽  
Mee Kum Kim ◽  
Jung Hwa Ko ◽  
Hyun Ju Lee ◽  
Won Ryang Wee ◽  
...  

2016 ◽  
Vol 57 (10) ◽  
pp. 1555
Author(s):  
Yun Hyup Na ◽  
Joo Youn Shin ◽  
Jong Hyun Lee ◽  
Jin Hyoung Kim ◽  
Do Hyung Lee

Author(s):  
Pratima Sahu ◽  
Amit Kumar Mishra

Background: Posterior capsular opacification (PCO) which is also known as “after cataract” or “secondary cataract”, is the most common complication of cataract surgery, with an incidence of 20-50%. The current study was conducted in a tertiary hospital of Odisha with an objective to find out the determinants of PCO among patients with defective vision attending the outdoor patient department of Ophthalmology.Methods: A hospital based descriptive study was conducted among the patients attending the ophthalmology out patient department of a tertiary hospital of Odisha. The detail history regarding the type of surgical procedure used for cataract extraction and the type of Intra Ocular Lens (IOL) implanted, duration of post-operative period was collected from the available documents and ophthalmic examination of the participants.Results: In the present study, 184 participants were included and examined. Fifty percent of the participants had undergone conventional extra capsular cataract extraction procedure. In 86.95% participants, the IOL used was Poly Methyl Methacrylate lens (PMMA). In 26.08% of the participants the development of PCO was within 12 to 36 months of cataract surgery. The average duration of PCO development recorded for participants <20 years was 3 months.Conclusions: Most of the participants included in the study with PCO had undergone conventional ECCE surgery, implanted PMMA lens, IOL with round edge and had a duration of 12-36 months between cataract surgery and PCO development. The average duration of PCO development is less among younger participants which gradually increases with increase in age.


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