scholarly journals Associação entre vírus respiratórios e asma em crianças e adolescentes: uma revisão de escopo

2022 ◽  
Vol 11 (1) ◽  
pp. e3511124297
Author(s):  
Giselmo Pinheiro Lopes ◽  
Rose Daiana Cunha dos Santos ◽  
João Victor Ferreira Araújo ◽  
Vanessa Graziela da Cunha Medeiros ◽  
Alessandra Gomes Mesquita ◽  
...  
Keyword(s):  
Respiratory Virus

A asma é uma doença inflamatória crônica que acomete as vias aéreas e causa sintomas como dispneia, sibilos e tosse. Estima-se que existam cerca de 339 milhões de pessoas convivendo com asma no mundo e que a influência de microrganismos seja considerada um fator de risco para o aparecimento de asma na infância. Diante disso, esta revisão teve por objetivo analisar a relação entre a exposição a vírus respiratórios e a ocorrência de asma em crianças e adolescentes. Para tal metodologia, fora realizada buscas nas bases de dados Pubmed e Science Direct por artigos em inglês utilizando a estratégia de pesquisa respiratory virus AND (children OR adolescence) AND (wheezing OR asthma). Dos 2.717 artigos encontrados, apenas 17 foram incluídos na revisão com base nos critérios de inclusão e exclusão considerados. Os resultados mostraram que o Rinovírus e o Vírus Sincicial Respiratório foram os mais prevalentes nos artigos. Adicionalmente, ocorreram detecções para Adenovírus, Coronavírus, Enterovírus, Bocavírus, Influenza, Metapneumovírus e Parainfluenza, além da presença de coinfecção entre os vírus destacados e com bactérias. Os achados nesta revisão poderão auxiliar na elaboração de estratégias em saúde pública para se prevenir exacerbações de doenças respiratórias induzidas por vírus, tendo em vista que muitas das infecções causadas por esses agentes têm caráter sazonal.

Characteristics of Respiratory Virus Infection During the Outbreak of 2019 Novel Coronavirus in Beijing

2020 ◽  
Author(s):  
Yan Li ◽  
Jiangshan Wang ◽  
Chunting Wang ◽  
Qiwen Yang ◽  
Yingchun Xu ◽  
...  
Keyword(s):  
Virus Infection ◽  
Respiratory Virus ◽  
Respiratory Virus Infection ◽  
Novel Coronavirus

Immunizations and vaccines: a decade of successes and reversals, and a call for ‘vaccine diplomacy’

2019 ◽  
Vol 11 (5) ◽  
pp. 331-333 ◽  
Author(s):  
Peter J Hotez
Keyword(s):  
Respiratory Virus ◽  
Neglected Tropical Diseases ◽  
Tropical Diseases ◽  
Virus Infections ◽  
Vaccination Programs ◽  
Vaccine Preventable Diseases ◽  
Health Gains ◽  
Potential Development ◽  
Respiratory Virus Infections ◽  
New Vaccines

Abstract Over the last decade we have seen extraordinary public health gains due to expansions in global vaccination programs led by United Nations (UN) agencies, including Gavi, the Vaccine Alliance, UNICEF and the WHO. These initiatives have reduced childhood deaths from measles, tetanus and other vaccine-preventable diseases by almost one half. There is additional excitement over the potential development and introduction of new vaccines to prevent highly lethal respiratory virus infections, as well as tuberculosis, malaria, HIV/AIDS and several neglected tropical diseases. However, these successes are under threat due to political instability, conflict and an accelerating antivaccine movement. New initiatives in vaccine diplomacy will be required to combat these challenges.

Respiratory viral testing and antibacterial treatment in patients hospitalized with community-acquired pneumonia

2020 ◽  
pp. 1-9
Author(s):  
Michael Klompas ◽  
Peter B. Imrey ◽  
Pei-Chun Yu ◽  
Chanu Rhee ◽  
Abhishek Deshpande ◽  
...  
Keyword(s):  
Retrospective Cohort ◽  
Respiratory Virus ◽  
Respiratory Viruses ◽  
Community Acquired Pneumonia ◽  
Blood Cultures ◽  
Antibacterial Treatment ◽  
Viral Pathogens ◽  
Antimicrobial Utilization ◽  
Viral Testing ◽  
Virus Testing

Abstract Objective: Viruses are more common than bacteria in patients hospitalized with community-acquired pneumonia. Little is known, however, about the frequency of respiratory viral testing and its associations with antimicrobial utilization. Design: Retrospective cohort study. Setting: The study included 179 US hospitals. Patients: Adults admitted with pneumonia between July 2010 and June 2015. Methods: We assessed the frequency of respiratory virus testing and compared antimicrobial utilization, mortality, length of stay, and costs between tested versus untested patients, and between virus-positive versus virus-negative patients. Results: Among 166,273 patients with pneumonia on admission, 40,787 patients (24.5%) were tested for respiratory viruses, 94.8% were tested for influenza, and 20.7% were tested for other viruses. Viral assays were positive in 5,133 of 40,787 tested patients (12.6%), typically for influenza and rhinovirus. Tested patients were younger and had fewer comorbidities than untested patients, but patients with positive viral assays were older and had more comorbidities than those with negative assays. Blood cultures were positive for bacterial pathogens in 2.7% of patients with positive viral assays versus 5.3% of patients with negative viral tests (P < .001). Antibacterial courses were shorter for virus-positive versus -negative patients overall (mean 5.5 vs 6.4 days; P < .001) but varied by bacterial testing: 8.1 versus 8.0 days (P = .60) if bacterial tests were positive; 5.3 versus 6.1 days (P < .001) if bacterial tests were negative; and 3.3 versus 5.2 days (P < .001) if bacterial tests were not obtained (interaction P < .001). Conclusions: A minority of patients hospitalized with pneumonia were tested for respiratory viruses; only a fraction of potential viral pathogens were assayed; and patients with positive viral tests often received long antibacterial courses.

scholarly journals Microfluidic sample preparation for respiratory virus detection: A review

2021 ◽  
Vol 15 (1) ◽  
pp. 011503
Author(s):  
Ryan Zenhausern ◽  
Chia-Hung Chen ◽  
Jeong-Yeol Yoon
Keyword(s):  
Sample Preparation ◽  
Respiratory Virus ◽  
Virus Detection

scholarly journals Histological evidence of pulmonary micro-thrombosis and vasculitis in life-threatening respiratory virus diseases

2020 ◽  
Author(s):  
Heather W Dolby ◽  
Philippe M D Potey ◽  
Annika Wilder-Smith ◽  
Sara Clohisey ◽  
Jonathan E Millar ◽  
...  
Keyword(s):  
Respiratory Virus ◽  
Virus Infections ◽  
Virus Diseases ◽  
Histological Evidence ◽  
Life Threatening ◽  
Respiratory Virus Infections

Abstract Pulmonary micro-thrombosis and vasculitis occur in fatal COVID-19. To determine if these processes occur in other life-threatening respiratory virus infections we identified autopsy studies of fatal influenza(n=455 patients), SARS(n=37), MERS(n=2), adenovirus(n=34) and RSV(n=30). Histological evidence of thrombosis was frequently present in adults with fatal influenza and SARS, with vasculitis also reported.

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