Cardiac MRI and Transthoracic Echocardiography of Left Ventricular Myocardial Noncompaction in A Patient with Congestive Heart Failure: A Case Report

The objective of this report is to present a case of Graves’ thyrotoxicosis-induced cardiomyopathy. This is a case of a 26 year old woman that presented with severe symptomatic congestive heart failure and was subsequently diagnosed with dilated cardiomyopathy secondary to Graves’ disease. Despite an initial left ventricular systolic ejection fraction of 20% on echocardiography, treatment with anti-thyroid agents led to rapid improvement of her clinical status and normalization of her ejection fraction. The proposed mechanisms underlying the development of systolic dysfunction in thyrotoxicosis are discussed and the literature on similar cases previously reported is highlighted. Cardiomyopathy should be considered even in young patients with Graves’ thyrotoxicosis.

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Reverse takotsubo cardiomyopathy caused by patent foramen ovale-related cryptogenic stroke: a case report

European Heart Journal - Case Reports ◽

10.1093/ehjcr/ytaa407 ◽

2020 ◽

Author(s):

Hiroya Takafuji ◽

Junya Arai ◽

Kuniyasu Saigusa ◽

Kotaro Obunai

Keyword(s):

Heart Failure ◽

Case Report ◽

Acute Heart Failure ◽

Takotsubo Cardiomyopathy ◽

Transthoracic Echocardiography ◽

Patent Foramen Ovale ◽

Cryptogenic Stroke ◽

Left Ventricular ◽

Heart Team ◽

Foramen Ovale

Abstract Background Reverse takotsubo cardiomyopathy (rTTC) is recognized as an atypical type of TTC. It has been suggested that neurological events are typical trigger of rTTC, especially in young individuals. Case summary In this case report, we describe a 16-year-girl who presented with neurological deficits due to embolic stroke and acute heart failure. Transthoracic echocardiography on admission revealed a severely reduced left ventricular (LV) function with akinesis of basal to mid LV, but normal contraction in apex. Coronary computed tomography angiography confirmed unobstructed coronary arteries. Two weeks later, her LV wall motion and ejection fraction were completely normalized. Transthoracic echocardiography and transoesophageal echocardiography demonstrated no evidence of intracardiac thrombus but showed a patent foramen ovale (PFO) with large shunt. After thorough work-up and brain–heart team discussion, we concluded that the patient developed rTTC due to cryptogenic stroke related with her PFO. She underwent percutaneous PFO closure for secondary prevention with good clinical course. Discussion Reverse TTC is a rare condition. It should be considered in stroke patients with acute heart failure. Quick diagnosis and management with brain–heart team is crucial for better prognosis.

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A Case Report of Isolated Left Ventricular Non-Compaction Presenting with Congestive Heart Failure and Intramural Thrombus

Yangtze Medicine ◽

10.4236/ym.2019.31007 ◽

2019 ◽

Vol 03 (01) ◽

pp. 64-71

Author(s):

Laxmi Narayan Goit ◽

Shaning Yang

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Case Report ◽

Left Ventricular

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P671Impacts of echocardiography-defined pulmonary hypertension on clinical outcome in patients with multiple myeloma

European Heart Journal ◽

10.1093/eurheartj/ehz747.0277 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

S A Bae ◽

H J Yoon ◽

K H Kim ◽

H Y Kim ◽

H J Park ◽

...

Keyword(s):

Heart Failure ◽

Multiple Myeloma ◽

Congestive Heart Failure ◽

Pulmonary Hypertension ◽

Clinical Outcome ◽

Transthoracic Echocardiography ◽

Acute Decompensated Heart Failure ◽

Management Strategies ◽

Sudden Cardiac Arrest ◽

Left Ventricular

Abstract Background Pulmonary hypertension (PH) is a rarely reported complication of multiple myeloma (MM). PH of MM is usually mild to moderate and can be secondary to a variety of conditions, including left ventricular dysfunction, diastolic dysfunction, chronic heart failure, treatment-related toxicity, thrombophilic condition and precapillary involvement. However, only few reports regarding PH in MM incidence and prognosis exist up to now. Purpose The purpose of this study was to investigate the risk factors of transthoracic echocardiography-defined PH and its impact on clinical outcome in patients with MM. Methods A total of 277 MM patients was included and divided into 2 groups–those non-pulmonary hypertension (PH) or those with PH, based on the results of the transthoracic echocardiography (TTE); PH group (n=143, 60.9±9.2 years, 68 males) versus non-PH group (n=134, 55.9±11.5 years, 72 males). We analyzed propensity score matching and multiple imputation method were used to deal with the missing data in echocardiographic characteristics. Results During the follow-up period (median 618 days), all-cause death occurred in 79 (28.5%) patients and 41 patients (14.8%) died from cardiovascular causes (including acute decompensated heart failure, fatal MI, sudden cardiac arrest). In the Kaplan-Meier survival analysis of crude population and propensity-matched population, cumulative overall survival and cardiovascular death (CVD)-free survival were significantly lower in the PH group than in the non-PH group (p<0.001). In propensity-matched population, estimated pulmonary artery pressure >35mmHg in TTE, congestive heart failure, and DM were significant independent predictors of all-cause death. KM curves in MM stratified by PH Conclusion This study demonstrates that the presence of PH, congestive heart failure, and DM is an independent prognostic factor for all-cause death in MM patients with MM. These results highlight the risk associated cardiovascular disease in MM patients and emphasize that management strategies that prevent deterioration of cardiac function are essential.

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