scholarly journals Beneficial Effects of Adding Ketamine to Intravenous Patient-Controlled Analgesia with Fentanyl after the Nuss Procedure in Pediatric Patients

2012 ◽  
Vol 53 (2) ◽  
pp. 427 ◽  
Author(s):  
Moon Ho Cha ◽  
Ji Hye Eom ◽  
Yoon Sook Lee ◽  
Woon Young Kim ◽  
Young Cheol Park ◽  
...  
2005 ◽  
Vol 49 (5) ◽  
pp. 624 ◽  
Author(s):  
Ki Ryang Ahn ◽  
Ji Weon Chung ◽  
Jin Hyeong Kwon ◽  
Kyu Sik Kang ◽  
Jung Suk Lee ◽  
...  

2019 ◽  
Vol 24 (1) ◽  
pp. 34-38 ◽  
Author(s):  
Katherine Lemming ◽  
Gary Fang ◽  
Marcia L. Buck

OBJECTIVES Use of lidocaine as part of a multimodal approach to postoperative pain management has increased in adults; however, limited information is available regarding safety and tolerability in pediatrics. This study's primary objective was to evaluate the incidence of adverse effects related to lidocaine infusions in a sample of pediatric patients. METHODS A retrospective analysis was conducted in pediatric patients receiving lidocaine infusion for the management of postoperative analgesia at the University of Virginia Health System. RESULTS A total of 50 patients with 51 infusions were included in the final analysis. The median patient age was 14 years (range, 2–17 years). The most frequent surgeries were spinal fusion (30%), Nuss procedure for pectus excavatum (16%), and nephrectomy (6%). The mean ± SD starting rate was 13.6 ± 6.5 mcg/kg/min. The mean infusion rate during administration was 15.2 ± 6.3 mcg/kg/min, with 14.4 ± 6.2 mcg/kg/min at discontinuation. The mean length of therapy was 30.6 ± 22 hours. A total of 12 infusions (24%) were associated with adverse effects, primarily neurologic ones, including paresthesias in the upper extremities (10%) and visual disturbances (4%). The average time to onset was 16.2 ± 15.2 hours. Seven infusions were discontinued, whereas the remaining infusions resulted in either dose reduction or continuation without further incident. No patients experienced toxicity requiring treatment with lipid emulsion. CONCLUSIONS In this sample, lidocaine was a well-tolerated addition to multimodal postoperative pain management in the pediatric population. Although adverse effects were common, they were mild and resolved with either dose reduction or discontinuation.


1988 ◽  
Vol 69 (3A) ◽  
pp. A772-A772 ◽  
Author(s):  
L. J. Means ◽  
H. M. Allen ◽  
S. J. Lookabill ◽  
G. Krishna

Author(s):  
María Velayos ◽  
Mercedes Alonso ◽  
Carlos Delgado-Miguel ◽  
Karla Estefanía-Fernández ◽  
Antonio J Muñoz-Serrano ◽  
...  

Abstract Introduction In recent years, pain protocols for pectus excavatum (PE) have incorporated cryoanalgesia through thoracoscopic approach. Since 2019, ultrasound-guided percutaneous cryoanalgesia (PCr) has been applied at our institution, either on the same day as the Nuss procedure or 48 hours before surgery. We carried out a preliminary retrospective review of patients with PE in whom PCr prior to surgery was performed at our institution between 2019 and 2021. Materials and Methods Two groups were evaluated: PCr on the same day (PCrSD) and PCr 48 hours before surgery (PCr48). Despite PCr, patients were treated with “patient-controlled analgesia” (PCA) with opioids for at least 24 hours, switching to conventional intravenous analgesia and oral analgesia in the following days. Demographic, clinical-radiological variables, PCA opioid use, pain grade according to the visual analog scale (VAS), and length of stay (LOS) were compared between the groups. A total of 20 patients were included (12 with PCrSD and 8 with PCr48), without significant differences in demographics or clinical-radiological variables. The overall median time of PCr was 65 minutes (55–127), with no differences between the groups. Results PCr48 group presented with significantly lower median number of hours of continuous PCA (24 vs. 32 hours; p = 0.031), lower median number of rescue boluses (11 vs. 18; p = 0.042), lower median VAS in the early postoperative hours (2 vs. 5.5; p = 0.043), and lower median LOS (3.5 vs. 5 days). Conclusion PCr performed 48 hours prior to surgery is more effective in terms of PCA requirements, VAS, and LOS when compared with cryoanalgesia on the same day.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Yu-Kai Huang ◽  
Chieh Chou ◽  
Chung-Liang Li ◽  
Hui-Gin Chiu ◽  
Yu-Tang Chang

Minimally invasive technology or laparoscopic surgery underwent a major breakthrough over the past two decades. The first experience of thoracoscopy in children was reported around 1980 for diagnosis of intrathoracic pathology and neoplasia. Up until the middle of the 1990s, the surgical community in Taiwan was still not well prepared to accept the coming era of minimally invasive surgery. In the beginning, laparoscopy was performed in only a few specialties and only relatively short or simple surgeries were considered. But now, the Taiwan’s experiences over the several different clinical scenarios were dramatically increased. Therefore, we elaborated on the experience about pectus excavatum: Nuss procedure, primary spontaneous hemopneumothorax, thoracoscopic thymectomy, and empyema in Taiwan.


PEDIATRICS ◽  
1972 ◽  
Vol 49 (4) ◽  
pp. 590-595
Author(s):  
Norman Jaffe ◽  
Demetrius Traggis ◽  
Lakshmi Das ◽  
Byung Soo Kim ◽  
Hie Won ◽  
...  

A two dosage therapeutic regimen of L-asparaginase was investigated to determine the differences in the production of abnormal reactions and remission induction in pediatric patients with leukemia. Among 35 patients, 17 were randomized to receive 200 I.U./kg daily for 2 weeks and 18, 5,000 I.U./kg twice weekly for 2 weeks. Of the 17 children on the daily schedule there were nine complete remissions and one improved marrow; among the 18 children in the twice-weekly schedule there were nine complete remissions, two partial remissions, and two improved marrows. The median duration of remission in each group was 9 weeks. Hypocellular marrows were noted in each regimen. Anaphylactoid reactions occurred only in the twice-weekly schedule. In the latter, one patient developed pancreatitis and another hyperglycemia not related to pancreatitis. Greater aberrations in the blood ammonia and serum amylase were noted in the twice-weekly regimen. A high intermittent dose schedule, while permitting less frequent clinic visits, increases the risk of side effects without adding to the beneficial effects of the drug.


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