Prevalence of hypoalbuminemia among tuberculosis patients receiving anti tuberculosis therapy: A cross sectional study

Background: Reaching a correct diagnosis is a challenge for physicians treating any of the 30% to 50% of pulmonary tuberculosis patients who have negative sputum cultures or who present with no sputum. Flexible bronchoscopy acquires special importance for these cases for whom empirical anti-tuberculosis therapy is the only option left. In our study we aimed to assess the diagnostic yield of flexible bronchoscopy in patients, suspected to have tuberculosis, whose sputum smears were negative. Methodology: In our hospital-based cross-sectional study, 42 patients were enrolled by consecutive sampling. Flexible bronchoscopy and selective bronchial washings were done in all patients. Results: Bronchoscopy lavage smears were positive for M. tuberculosis in 10 (23.8%) patients. Fifteen (35.7%) patients had positive culture. Conclusion: Flexible bronchoscopy has an important role in the diagnosis of patients suspected to have tuberculosis, whose sputum smears are negative or who can not produce sputum.

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Assessment of treatment interruption among pulmonary tuberculosis patients: A cross-sectional study

Journal of Pharmacy And Bioallied Sciences ◽

10.4103/0975-7406.160034 ◽

2015 ◽

Vol 7 (3) ◽

pp. 226 ◽

Cited By ~ 4

Author(s):

Srinivas Martha ◽

SatyaBhgath Gorityala ◽

UdayVenkat Mateti ◽

Venkateswarlu Konuru

Keyword(s):

Pulmonary Tuberculosis ◽

Treatment Interruption ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Tuberculosis Patients

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Effect of psychiatric co-morbidity on adherence to anti tubercular treatment: a cross sectional study from North India

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20210821 ◽

2021 ◽

Vol 8 (3) ◽

pp. 1325

Author(s):

Ravdeep Kaur ◽

Tarundeep Singh ◽

Shubh Mohan Singh ◽

Rajesh Kumar

Keyword(s):

Depressive Disorder ◽

Cross Sectional Study ◽

North India ◽

Directly Observed Therapy ◽

Cross Sectional ◽

Tuberculosis Patients ◽

Short Course ◽

Co Morbidity ◽

Mdr Tb ◽

Tuberculosis Therapy

Background: Study explores relationship between depressive disorder and adherence to DOTS (Directly Observed Therapy Short Course) and whether treatment of depressive disorder according to severity of depressive disorder should be an option to improve adherence to DOTS.Methods: Study included 182 newly diagnosed adult cases of tuberculosis who were on anti- tuberculosis therapy (ATT) as per program guidelines and were in third month under DOTS category I and category II therapy. Patients were screened for depressive and anxiety disorder using PHQ-9 and GAD-7. Modified ACTG baseline questionnaire was used to collect data about adherence and reasons for partial adherence.Results: Overall prevalence of depressive disorder amongst participants was found to be 37.9% and that of partial adherence (missed two or more than two doses) was 12.1%. Partial adherence was mostly seen in the first month, followed by third and second month of DOTS. Twenty- two percent patients with depressive disorder were partially adherent to ATT. Odds ratio suggests higher risk being partially adherent to ATT were greater in the participants who had depressive disorder.Conclusions: This study highlights the benefit of screening patients while diagnosing tuberculosis patients for depressive disorder, to improve disease outcome and reduce likelihood of MDR-TB.

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