Now a days it is a known fact that the oxidative stress is in the foreground of type-II diabetes mellitus. It is the main cause of macro and microvascular complications in type II diabetes mellitus. Oxidative stress can be served as a good marker of degree of diabetes in addition is HbA1C. Superoxide (O2.- ) is one of the free radical produced during oxidative stress. Superoxide dismutase (SOD) is an enzyme which quenches superoxide radicals produced due to oxidative stress. Hence it is very obvious that the estimation of SOD should be very sensitive and specific. To attain this aim we compared three different methods.
Key words: SOD, Diabetes, Oxidative stress, Superoxide Dismutase.