scholarly journals A Comparative study of endometrial thickness by transvaginal ultrasound and histopathological examination in perimenopausal women in a teaching medical college hospital

Author(s):  
Dr. KP Sowmya ◽  
Varshita KM
Author(s):  
Nicole Sequeira ◽  
Shannon Fernandes

Background: AUB is a commonly encountered complaint in peri- and postmenopausal women visiting OBG OPDs and accounts for about 70% of all gynaecological complaints. Key to management depends on the cause of AUB. Protocol has changed over the years from performing investigations randomly to a condition specific approach. This study aims to evaluate and compare the efficacy of transvaginal sonography and hysteroscopy in perimenopausal women with AUB and note its relation with histopathology.Methods: A prospective study was conducted on 103 women of 40-55 years presenting to the OBG OPD of Father Muller Medical College Hospital, Mangalore. All patients underwent a transvaginal scan to note the endometrial thickness followed by a hysteroscopy and biopsy. Endometrium was sent for histopathology. Findings of these modalities were correlated.Results: The diagnostic value of transvaginal sonography in relation to histopathology had a sensitivity and specificity of 33.33% and 95.95% for atrophic endometrium, 52.5% and 62.9% for proliferative, 29.41% and 79.41% for secretory, and 55.55% and 74.19% for hyperplastic. When compared to histopathology, hysteroscopy had a sensitivity and specificity of 100% and 92.3% for atrophic, 26.19% and 96.96% for proliferative, 27.07% and 98.59% for secretory, and 100% and 64.94% for hyperplastic endometrium. It had a sensitivity of 77.77% and a specificity of 92.92% for endometrial polyps. Agreement between TVS and histopathology based on kappa co-efficient was fair for atrophic endometrium but poor for proliferative, secretory and hyperplastic endometrium. Agreement between hysteroscopy and histopathology was moderate for atrophic endometrium and for endometrial polyps. It was fair for proliferative, secretory and hyperplastic endometrium.Conclusions: TVS seems to be a good initial method for evaluation of AUB. However, a subsequent hysteroscopy with biopsy is advisable to evaluate the cause of AUB.


2011 ◽  
Vol 18 (01) ◽  
pp. 46-50
Author(s):  
QAMAR-UR- NISA ◽  
HABIB ULLAH ◽  
TANWEER AHMED SHAIKH ◽  
Miss Hemlata ◽  
Fatima Memon ◽  
...  

Objective: To audit indications and histopathological diagnosis of hysterectomies performed at Muhammad Medical College hospital, Mirpurkhas. Study Design: Retrospective study. Place and Duration of Study: Department of Obstetrics and Gynaecology and Department of Pathology, Muhammad Medical College Hospital, Mirpurkhas Sindh from January to December 2008. Methodology: Data regarding symptoms and indications of hysterectomies performed during this year were collected from files and patient records. Histopathological reports of those patients were collected from department of pathology. The results were analyzed by percentages. Results: A total of 145 hysterectomies were performed in 2008. Mean age of patients was 45years ranging from 35-60 years and parity ranges from 4 – 10. Most common presenting complaints were excessive menstrual blood loss in 97(67%) patients, followed by some thing coming out of vagina 28(19%). Most common pre-operative diagnosis of fibroid was made in 44 (33%) followed by uterovaginal prolapse in 28(19%) and dysfunctional uterine bleeding (DUB) in 18(12%) of patients. Regarding histopathological diagnosis chronic cervicitis was the most commonly diagnosed pathology in 45 (31%) followed by fibroid in 25(17%) cases. Conclusions: A yearly audit should be conducted in every institute to collect data and to analyze the pattern of indication and lesions found on histopathological examination. 


2012 ◽  
Vol 18 (1) ◽  
pp. 23-29
Author(s):  
Md Mahmudul Huq ◽  
Mohammad Idrish Ali ◽  
SM Nazmul Huque ◽  
KM Nurul Alam ◽  
Md Abdus Sattar ◽  
...  

Objective: In this study 50 patients of neck swelling were studied to compare the findings with clinical diagnosis and histopathological report for its diagnostic reliability.Methods: This cross sectional study was done in ENT Department of Sher-E-Bangla Medical College Hospital, Barisal, Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka from July 2006 to December 2006. Fine needle aspiration cytology, MRI, CT scan, and histopathological examination of postoperative specimen of neck swelling, analyzed data presented by various tables, graphs and figures.Results: In the present series 50 cases of neck swelling were studied. Out of these 50 cases 19 were male and 31 were female. The male, female ratio was 1:1.63. Age range was 4 – 60 years with maximum frequency in the 4th decade with the 3rd and 2nd in the following suit. Most of the patient was poor. Clinical, cytological and histopathological diagnosis was available in all the cases. The three sorts of diagnoses were compared with each other. Histopathologically 12 cases were tubercular lymphadenopathy, 12 cases were nodular goiter, 5 cases were Metastatic carcinoma, 5 were thyroid carcinoma and another 5 cases were lymphoma, Rest were benign, congenital and nonspecific inflammatory conditions. Correct diagnosis was made by FNAC in 45 cases. In the rest 5 cases smear were unsatisfactory in 2 cases and gives inconclusive result, remaining 3 were follicular neoplasmand no definitive result were made which were subsequently diagnosed by histopathological examination as a follicular adenoma in 1 and follicular carcinoma in 2. Sensitivity of FNAC in the diagnosis of neck masses were found 91% for tuberculosis, 100% for metastatic carcinoma and also for salivary gland tumour. In case of nodular goiter sensitivity was 92%. But it is only 60% sensitive in case of thyroid malignancy, as FNAC can not demarcate clearly between follicular adenoma and follicular cell carcinoma. But its accuracy in diagnosing papillary carcinoma of thyroid was 100%.Conclusion: FNAC can reduce substantially the need of open biopsy for histopathological examination. Accuracy of FNAC will be improved with relevant information provided by clinicians.DOI: http://dx.doi.org/10.3329/bjo.v18i1.10410  Bangladesh J Otorhinolaryngol 2012; 18(1): 23-29


1970 ◽  
Vol 20 (1) ◽  
pp. 24-27
Author(s):  
M Razzak Mia ◽  
ARM Saifuddin Ekram ◽  
M Azizul Haque ◽  
M Raisuddin

This study was carried out in medicine and cardiology indoor of Rajshahi Medical College Hospital from November 2004 to October 2005. 100 cases were selected for this study in random manner. Sensitivity of ECG to diagnose LVH was found to be 87.5%, and specificity was only 50%. ECG is relatively insensitive and can't accurately identify the severity of LVH.   doi: 10.3329/taj.v20i1.3085 TAJ 2007; 20(1): 24-27


1970 ◽  
Vol 17 (2) ◽  
pp. 59-61 ◽  
Author(s):  
A Wazib ◽  
MZ Hossain ◽  
R Hasan ◽  
MB Alam

This prospective study was conducted in Dhaka Medical College Hospital during July 2006 to June 2007. 100 patients were included in the study among which forty seven received benzylpenicillin and fifty three was treated with ceftriaxone. The result of this study showed that mortality was similar in both groups but ceftriaxone had better outcome regarding duration of clinical features and hospital-stay. Key words: pyogenic meningitis; benzylpenicillin; ceftriaxone. DOI: 10.3329/jdmc.v17i2.6583J Dhaka Med Coll. 2008; 17(2) : 59-61


2017 ◽  
Vol 6 (2) ◽  
pp. 76-78
Author(s):  
Rooh E Zakaria ◽  
Farhana Dewan ◽  
Md Abdullah Yusuf ◽  
Mamunur Rahman ◽  
Mojammel Hauque

Background: Ovarian tumour causes great morbidity and mortality.Objective: The purpose of the present study was to analyze the different presentation of ovarian tumours to see the frequency and clinic-demographic characteristics of ovarian tumour.Methodology: This cross sectional study was conducted in the Department of Gynaecology & Obstetrics, Shaheed Suhrawardy Medical College, Dhaka during the period from January to June 2013 for a period of six months. Patient admitted in Department of Obstetrics Gynaecology ward in Shaheed Suhrawardy Medical College Hospital with provisional diagnosis of ovarian tumour were selected as study population. Proper permission was taken from the ethical committee of Shaheed Suhrawardy Medical College Hospital for this study. All the patients were informed about the various aspects of the study. Their verbal consents were taken. Women of all ages with ovarian tumour were included in this study. Women with all other tumour except ovarian tumour were excluded from this study. A thorough history variably collected, clinical examination and investigations was carried out. The result of benign and malignant ovarian neoplasms in regard to age parity, physical sign, vaginal examination, laparotomy findings, together with their macroscopic findings are tabulated separately. Histopathological examination was done by senior pathologists of ShSMCH.Result: A total 50 cases of ovarian tumour had been studied of which 26 (52%) were benign and 24(49%) were malignant ovarian tumours which were confirmed by histopathological examination (P>0.05). 28% and 12% patient with benign ovarian tumour were in age group of 18-34 years and 35-45 years and 14% patient with malignant ovarian tumour in age group >45 years (p>0.05). 32% patient with benign ovarian tumours came from poor socio economics condition and 20% from middle class, 28% patient with malignant ovarian tumour came from poor and 16% from middle class family. Out of 50 cases of ovarian tumour , 39 were married and 11 were unmarried. 51% patients did not use any contraceptives and 31% oral contraceptives (P<0.05). No family history was found in 92% patients. 16% patients with benign tumours were unmarried.Conclusion: In conclusion ovarian tumour are mostly benign of which middle age group are most commonly reported.J Shaheed Suhrawardy Med Coll, 2014; 6(2):76-78


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