scholarly journals ANTI-IDIOTYPIC MONOCLONAL ANTIBODIES AGAINST MORPHINE: PRODUCTION, PROPERTIES AND PROSPECTS OF USE

Biomeditsina ◽  
2019 ◽  
pp. 63-68 ◽  
Author(s):  
A. V. Trofimov ◽  
A. Ya. Rak ◽  
A. G. Berzina ◽  
L. I. Ulyanova ◽  
N. V. Gamaleya ◽  
...  
Keyword(s):  
Biological Activity ◽  
Monoclonal Antibodies ◽  
Enzyme Immunoassay ◽  
Cell Line ◽  
In Vitro Model ◽  
T98g Cell ◽  
Human Glioblastoma ◽  
Vitro Model

This paper describes a technique for producing anti-idiotypic monoclonal antibodies (Ab2) against two morphine derivatives. The specificity of the obtained antibodies was investigated using enzyme immunoassay. The biological activity of the antibodies was studied using an in-vitro model of human glioblastoma T98G cell line prolifer ation.

The Human Leukemic HL-60 Cell Line: An in Vitro Model for Cell Death Endpoint Identification

1996 ◽  
Vol 24 (4) ◽  
pp. 581-587
Author(s):  
Cristiana Zanetti ◽  
Arrnalaura Stammati ◽  
Orazio Sapora ◽  
Flavia Zucco
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
In Vitro Model ◽  
Leukemia Cell ◽  
Promyelocytic Leukemia ◽  
Leukemia Cell Line ◽  
Cell Type ◽  
Vitro Model ◽  
Promyelocytic Leukemia Cell Line

The aim of this study was to investigate the endpoints related to cell death, either necrosis or apoptosis, induced by four chemicals in the promyelocytic leukemia cell line, HL-60. Cell morphology, DNA fragmentation, cytofluorimetric analysis and oxygen consumption were used to classify the type of cell death observed. In our analysis, we found that not all the selected parameters reproduced the differences observed in the cell death caused by the four chemicals tested. As cell death is a very complex phenomenon, several factors should be taken into account (cell type, exposure time and chemical concentration), if chemicals are to be classified according to differences in the mechanisms more directly involved in cell death.

scholarly journals Approximation of immune response abilities in salmonid gills using the RTgill-W1 cell line as an in vitro model

2016 ◽  
Vol 53 ◽  
pp. 74
Author(s):  
Claudio Alvarez ◽  
Paula Santana ◽  
Francisco Donoso ◽  
Felipe Ramírez ◽  
Jimena Cortés ◽  
...  
Keyword(s):  
Immune Response ◽  
Cell Line ◽  
In Vitro Model ◽  
Vitro Model

In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies

2018 ◽  
Vol 273 ◽  
pp. 13-20 ◽  
Author(s):  
Hanne Kinnunen Bown ◽  
Catherine Bonn ◽  
Stefan Yohe ◽  
Daniela Bumbaca Yadav ◽  
Thomas W. Patapoff ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
In Vitro Model ◽  
Vitro Model

The murine enterocyte cell line Mode-K is a novel and reliable in vitro model for studies on gluten toxicity

2020 ◽  
Vol 140 ◽  
pp. 111331 ◽  
Author(s):  
Diomira Luongo ◽  
Lucia Treppiccione ◽  
Francesco Maurano ◽  
Mauro Rossi ◽  
Paolo Bergamo
Keyword(s):  
Cell Line ◽  
In Vitro Model ◽  
Vitro Model

scholarly journals Optimization of an oral mucosa in vitro model based on cell line TR146

2020 ◽  
Vol 8 (2) ◽  
pp. 1748459 ◽  
Author(s):  
Grace C. Lin ◽  
Tamara Leitgeb ◽  
Alexandra Vladetic ◽  
Heinz-Peter Friedl ◽  
Nadine Rhodes ◽  
...  
Keyword(s):  
Cell Line ◽  
Oral Mucosa ◽  
In Vitro Model ◽  
Model Based ◽  
Vitro Model

In vitro model of angiogenesis using a human endothelium-derived permanent cell line: Contributions of induced gene expression, G-proteins, and integrins

1992 ◽  
Vol 153 (3) ◽  
pp. 437-449 ◽  
Author(s):  
Jeffrey Bauer ◽  
Michael Margolis ◽  
Clara Schreiner ◽  
Cora-Jean Edgell ◽  
Jane Azizkhan ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Line ◽  
G Proteins ◽  
In Vitro Model ◽  
Permanent Cell Line ◽  
Permanent Cell ◽  
Vitro Model ◽  
Human Endothelium
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