scholarly journals Is there any connection between method of priming extracorporeal circuit and cerebral oximetry results?

2019 ◽  
Vol 1 (16) ◽  
pp. 22-27
Author(s):  
V. V. Basylev ◽  
M. E. Evdokimov ◽  
M. A. Pantyuhina ◽  
M. V. Kokushkin

Objectives. To compare the influence of different priming techniques on cerebral oximetry results during CPB in adult patients.Methods. This study is a single-center retrospective review of data collected from adult patients who underwent isolated CABG with CPB between January and December, 2016. The patients were divided into two standardized groups with the sole difference between them being the method of priming CPB circuit: the first one was the group where we used our modified retrograde method of priming (n = 45) and the second one was the group with standard priming (n = 45). Hematocrit, hemoglobin, cerebral oxygenation were evaluated at the following points: beginning of the operation, start of CPB, cross clamping, 15, 30, 45 minutes and the end of CPB and the end of operation.Results. In the first group indices of cerebral oximetry were higher comparing to the second group at list of the 45 minutes of CPB (р < 0,001). For the first 15 minutes of CPB hematocrit was also higher in the first group. Priming volume and the need for blood transfusion or ultrafiltration were also smaller in the first group.Conclusion. Modified priming technique allows to maintain higher indices of cerebral oximetry, decreases volume overload and the need for blood transfusion comparing to standard technique.

Perfusion ◽  
2016 ◽  
Vol 32 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Milo Engoren ◽  
Russell R. Brown ◽  
Anna Dubovoy

Purpose: Acute anemia is associated with both cerebral dysfunction and acute kidney injury and is often treated with red blood cell transfusion. We sought to determine if blood transfusion changed the cerebral oximetry entropy, a measure of the complexity or irregularity of the oximetry values, and if this change was associated with subsequent acute kidney injury. Methods: This was a retrospective, case-control study of patients undergoing cardiac surgery with cardiopulmonary bypass at a tertiary care hospital, comparing those who received a red blood cell transfusion to those who did not. Acute kidney injury was defined as a perioperative increase in serum creatinine by ⩾26.4 μmol/L or by ⩾50% increase. Entropy was measured using approximate entropy, sample entropy, forbidden word entropy and basescale4 entropy in 500-point sets. Results: Forty-four transfused patients were matched to 88 randomly selected non-transfused patients. All measures of entropy had small changes in the transfused group, but increased in the non-transfused group (p<0.05, for all comparisons). Thirty-five of 132 patients (27%) suffered acute kidney injury. Based on preoperative factors, patients who suffered kidney injury were similar to those who did not, including baseline cerebral oximetry levels. After analysis with hierarchical logistic regression, the change in basescale4 entropy (odds ratio = 1.609, 95% confidence interval = 1.057–2.450, p = 0.027) and the interaction between basescale entropy and transfusion were significantly associated with subsequent development of acute kidney injury. Conclusions: The transfusion of red blood cells was associated with a smaller rise in entropy values compared to non-transfused patients, suggesting a change in the regulation of cerebral oxygenation, and these changes in cerebral oxygenation are also associated with acute kidney injury.


2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
P Brenner ◽  
S Daebritz ◽  
S Kainzinger ◽  
I Kaczmarek ◽  
R Sodian ◽  
...  

Author(s):  
Emily E. Gaster ◽  
Christie A. Riemer ◽  
Jenna L. Aird ◽  
Brian J. King ◽  
Rokea A. el‐Azhary ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Aura Silva ◽  
Ana Liza Ortiz ◽  
Carlos Venâncio ◽  
Almir P. Souza ◽  
Luísa Maria Ferreira ◽  
...  

Bleeding changes the haemodynamics, compromising organ perfusion. In this study, the effects of bleeding followed by replacement with hydroxyethyl starch 130/0.4 (HES) or lactated Ringer’s (LR) on cerebral oxygenation and electroencephalogram-derived parameters were investigated. Twelve young pigs under propofol-remifentanil anaesthesia were bled 30 mL/kg and, after a 20-minute waiting period, volume replacement was performed with HES (GHES;N=6) or LR (GRL;N=6). Bleeding caused a decrease of more than 50% in mean arterial pressure (P<0.01) and a decrease in cerebral oximetry (P=0.039), bispectral index, and electroencephalogram total power (P=0.04andP<0.01, resp.), while propofol plasma concentrations increased (P<0.01). Both solutions restored the haemodynamics and cerebral oxygenation similarly and were accompanied by an increase in electroencephalogram total power. No differences between groups were found. However, one hour after the end of the volume replacement, the cardiac output (P=0.03) and the cerebral oxygenation (P=0.008) decreased in the GLRand were significantly lower than in GHES(P=0.02). Volume replacement with HES 130/0.4 was capable of maintaining the cardiac output and cerebral oxygenation during a longer period than LR and caused a decrease in the propofol plasma concentrations.


2007 ◽  
Vol 12 (9) ◽  
pp. 1134-1142 ◽  
Author(s):  
Frank Mayer ◽  
Hermann Aebert ◽  
Maximilian Rudert ◽  
Alfred Königsrainer ◽  
Marius Horger ◽  
...  

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