Experience of using specialized mixture of enteral nutrition in children with nutritive deficiency in cystic fibrosis

Сystic fibrosis is an autosomal recessive hereditary multisystem disease which is characterized by severe exocrine pancreatic insufficiency, chronic lung disease, and protein-energy malnutrition. Some studies have indicated that the body mass index is an independent factor which adversely affected survival of patients with cystic fibrosis. There is a direct correlation between body mass index, lung function and life expectancy. Objective. To determine the effectiveness and tolerability of the product for children’s dietary nutrition ‘NUTRINIdrink with dietary fibre (neutral taste)’ for children over one year of age for enteral nutrition in cystic fibrosis complicated by protein-energy deficiency.

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P130 PROTEIN ENERGY MALNUTRITION IN OESOPHAGEAL CANCER PATIENTS WITH OVERWEIGHT AND NORMAL BODY MASS INDEX (BMI)

Clinical Nutrition Supplements ◽

10.1016/s1744-1161(09)70180-2 ◽

2009 ◽

Vol 4 (2) ◽

pp. 80

Author(s):

W. Azam ◽

J.A. Catton

Keyword(s):

Body Mass Index ◽

Cancer Patients ◽

Body Mass ◽

Oesophageal Cancer ◽

Protein Energy Malnutrition ◽

Normal Body Mass Index ◽

Normal Body ◽

Protein Energy

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Pressure sores among malnourished necropsied adults - preliminary data

Revista do Hospital das Clínicas ◽

10.1590/s0041-87812000000300002 ◽

2000 ◽

Vol 55 (3) ◽

pp. 79-82 ◽

Cited By ~ 5

Author(s):

Daniel Ferreira da Cunha ◽

Ricardo Boggio Frota ◽

Maysa Silva Arruda ◽

Selma Freire de Carvalho da Cunha ◽

Vicente de Paula Antunes Teixeira

Keyword(s):

Heart Failure ◽

Body Mass Index ◽

Congestive Heart Failure ◽

Body Mass ◽

Water Retention ◽

Protein Energy Malnutrition ◽

Male Gender ◽

Pressure Sores ◽

Peripheral Vascular ◽

Protein Energy

Pressure sores are common among bedridden, elderly, or malnourished patients, and may occur in terminal ill patients because of impaired mobility, fecal or urinary incontinence, and decreased healing capacity. The aim of this study was to compare frequency of pressure sores between malnourished and non-malnourished necropsied adults. METHOD: All (n = 201) adults (age <FONT FACE="Symbol">³</font> 18 years) autopsied between 1986 and 1996 at the Teaching Hospital of Triangulo Mineiro Medical School (Uberaba) were eligible for the study. Gender, race, weight, height and main diagnoses were recorded. Ninety-six cases were excluded because of probable body water retention (congestive heart failure, hepatic insufficiency, nephrotic syndrome) or pressure sores secondary to peripheral vascular ischemia. Body mass index (BMI) was used to define malnourished (BMI < 18.5 kg/m²) and non-malnourished (BMI > 18.5kg/m²) groups. RESULTS: Except for weight (42.5kg; range: 28-57 vs. 60; 36-134.5kg) and BMI (16.9; range: 12.4-18.5 vs. 22.7; range: 18.5-54.6kg/m²), respectively, there were no statistical differences among 43 malnourished and 62 non-malnourished cases in relation to age (54.9 ± 20.4 vs. 52.9 ± 17.9 years), percentage of white persons (74.4 vs. 64.5%), male gender (76.7 vs. 69.3%) and main diagnoses. Five malnourished (11.6%) and 7 (11.5%) non-malnourished cases had pressure sores (p=0.89). CONCLUSION: Pressure sores were equally common findings in necropsied persons with protein-energy malnutrition, as assessed by body mass index.

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Harmful effects of malnutrition and possible sustainable solution

International Journal of Clinical Biochemistry and Research ◽

10.18231/j.ijcbr.2021.056 ◽

2022 ◽

Vol 8 (4) ◽

pp. 260-264

Author(s):

S Ravichandran ◽

Mahrukh Mehraj ◽

Fathima Feroz ◽

R M Madhumitha Sri

Keyword(s):

Immune System ◽

Lean Body Mass ◽

Body Mass ◽

Protein Energy Malnutrition ◽

Food Prices ◽

The Body ◽

Essential Nutrients ◽

Protein Energy ◽

Harmful Effects ◽

Muscle Functions

Malnutrition is a condition that results from eating a diet that does not supply a healthy amount of one or more nutrients. It is a condition characterized by lack of one or more essential nutrients from the diet or a surplus of some nutrients which affect the body negatively. Malnutrition consists of two types: undernutrition and overnutrition. Undernutrition involves the deficiency of macronutrients like protein or calories and micronutrients like iron, iodine and many more. Protein energy malnutrition is caused by the inadequate intake of protein and calories. It is further classified in three types, kwashiorkor, marasmus and marasmic kwashiorkor. Malnutrition mainly affects an individual’s immune system, lean body mass, cardio-respiratory functions, muscle functions. Malnutrition can be caused due to many factors including unavailability of food, poverty, higher food prices and many more. Strategies like biofortification and supplementation are used for the treatment of malnutrition.

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Impact of the body mass index on the prevalence of protein energy wasting (PEW) syndrome and diabetes in patients on maintenance hemodialysis (MHD)

Clinical Nutrition ◽

10.1016/j.clnu.2018.06.1752 ◽

2018 ◽

Vol 37 ◽

pp. S210

Author(s):

M.C. Terroba Larumbe ◽

C. Crespo Soto ◽

M. Gonzalez Sagrado ◽

B. Gomez Giralda ◽

F. Nuñez Ortega ◽

...

Keyword(s):

Body Mass Index ◽

Body Mass ◽

The Body ◽

Maintenance Hemodialysis ◽

Protein Energy Wasting ◽

Protein Energy

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Combination of obesity and malnutrition in a patient with chronic alcoholic pancreatitis (case report)

Herald of Pancreatic Club ◽

10.33149/vkp.2020.01.05 ◽

2020 ◽

Vol 46 (1) ◽

pp. 43-48

Author(s):

N. S. Gavrilina ◽

L. Yu. Ilchenko ◽

I. G. Fedorov ◽

I. G. Nikitin

Keyword(s):

Body Mass Index ◽

Case Report ◽

Body Mass ◽

Pancreatic Insufficiency ◽

Modern Society ◽

Exocrine Pancreatic Insufficiency ◽

Alcoholic Pancreatitis ◽

Chronic Alcoholic Pancreatitis ◽

Chronic Alcoholic ◽

Enzyme Replacement

Eating disorder with its two extreme manifestations — obesity and trophological insufficiency (TI) — is one of the common problems of modern society. TI is often diagnosed in patients with chronic pancreatitis (CP); it occurs due to a limited amount of food intake, malabsorption, diabetes mellitus, and chronic alcoholism. TI severity correlates with severity of malabsorption and depletion of nutrients degree. However, TI verification in patients with CP is difficult due to the lack of uniform diagnostic recommendations. Anthropometric technique, laboratory (determination of the level of lymphocytes, albumin) and instrumental (computed tomography, X-ray absorptiometry, magnetic resonance imaging) diagnostics are usually used. The article presents a case report of combination of such two opposite states as obesity and malnutrition in a patient with CP. The patient was hospitalized with CP exacerbation and alcohol abuse. Examination revealed exocrine pancreatic insufficiency and mild malnutrition. Enzyme replacement therapy and additional oral sip feeding with a positive effect were prescribed. Exocrine pancreatic insufficiency stopped after 10 weeks of treatment, but malnutrition remained and required a longer course of treatment. Relevance of this problem, main difficulties of diagnosis are presented in the article. Anthropometric indices, body mass index, lymphocytes, total protein, albumin need to be measured in all patients. Using only body mass index leads to hypodiagnosis of malnutrition in patients with CP.

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Percutaneous endoscopic gastrostomy in comprehensive preparing the patients with severe body mass defciency for lung transplantation

Transplantologiya The Russian Journal of Transplantation ◽

10.23873/2074-0506-2019-11-1-55-60 ◽

2019 ◽

Vol 11 (1) ◽

pp. 55-60

Author(s):

M. Sh. Khubutiya ◽

A. M. Gasanov ◽

E. A. Tarabrin ◽

T. E. Kallagov ◽

E. I. Pervakova ◽

...

Keyword(s):

Body Mass Index ◽

Cystic Fibrosis ◽

Enteral Nutrition ◽

Lung Transplantation ◽

Body Mass ◽

Percutaneous Endoscopic Gastrostomy ◽

Lung Diseases ◽

Comparison Group ◽

Waiting List ◽

Endoscopic Gastrostomy

Introduction. Currently, lung transplantation is an approved method for treating a wide range of end-stage lung diseases refractory to medical or surgical treatments when patient's life expectancy without transplantation makes no more than two years.The aim was to evaluate the efficacy of continuous nutritional support via percutaneous endoscopic gastrostomy in potential recipients of lung transplantation with a Body Mass Index under 16 kg/m2.Material and methods. The study was based on the analysis of 93 potential recipients with various lung diseases; 27 of them with diagnosed cystic fibrosis. The enteral nutrition results of the patients with cystic fibrosis whose Body Mass Index (BMI) was under 16 kg/m2 were assessed by the increment in BMI and compared between those (15) fed via gastrosomy and those (22) fed per os.Results. As a result of enteral nutrition via the gastrostomy in the daytime and at night, the majority of recipients (73.3% of cases) had the Body Mass Index (BMI) corrected from 0.1 to 4.91 kg/m2 during the first year, the mean BMI increment made 1.87 ± 0.4 kg/m2. After the BMI correction, 11 of the 15 potential recipients were included in the waiting list, and 6 of them (40%) underwent lung transplantation. In the comparison group, the BMI increment was 0.9 ± 0.3 kg/m2, also having reached a significant difference compared to the baseline (p = 0.04). However, the BMI increment in the main group was significantly higher than in the comparison group (p = 0.02).Conclusion. A statistically significant increase in BMI in a group of patients with cystic fibrosis and BMI under 16 kg/m2, has been demonstrated after percutaneous endoscopic gastrostomy, which allows extending the criteria for the inclusion in the waiting list for lung transplantation.

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Cystic Fibrosis

10.1093/med/9780190685157.003.0023 ◽

2018 ◽

Author(s):

Jamey Snell ◽

Thomas J. Mancuso

Keyword(s):

Cystic Fibrosis ◽

Lung Disease ◽

Past History ◽

Pancreatic Insufficiency ◽

Exocrine Pancreatic Insufficiency ◽

Pulmonary Insufficiency ◽

Dependent Diabetes Mellitus ◽

Exocrine Function ◽

Primary Defect ◽

Multisystem Disease

Cystic fibrosis (CF) is an inherited, autosomal recessive, multisystem disease. Dysfunction of the cystic fibrosis transmembrane conductance regulator protein (CFTR) in epithelial cells is the primary defect in CF. Defects in CFTR are the cause for lung disease, exocrine pancreatic insufficiency and failure, male infertility, and liver disease. CF can present with a variety of respiratory and gastrointestinal signs, including meconium ileus in the newborn period, hypernatremic dehydration, pulmonary insufficiency, nasal polyps, and insulin-dependent diabetes mellitus. As affected children grow, dysfunction in CFTR leads to chronic and progressive lung disease, characterized by suppurative infection and the development of bronchiectasis. CFTR dysfunction also affects exocrine function, leading to pancreatic insufficiency, malabsorption, and growth failure. In the past, history and physical exam with sweat chloride testing were the cornerstones of diagnosis. Diagnosis is now made with the newborn screening test for immunoreactive trypsinogen.

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