scholarly journals Normative data on transcranial magnetic stimulation motor evoked potential from the tongue

2020 ◽  
pp. 24-28
Author(s):  
V. B. Voitenkov ◽  
V. N. Komantsev ◽  
A. V. Klimkin ◽  
M. A. Bedova ◽  
E. V. Ekusheva ◽  
...  
Keyword(s):  
Age Differences ◽  
Normative Data ◽  
Evoked Potential ◽  
Clinical Neurophysiology ◽  
Motor Evoked Potential ◽  
Single Pulse ◽  
Middle Line ◽  
Healthy Individuals ◽  
Average Amplitude ◽  
Average Latency

Our aim was to determine parameters of motor evoked potential (MEP) from the tongue in healthy persons.Methods. 25 healthy individuals (average age 22.4 ± 6.2 years, range 18–41 years, 12 females & 13 males) were enrolled. All underwent diagnostic TMS, single-pulse protocol, 90-sm round coil, Neiro-MS-D device. Coil was placed on Fz point, registration was performed by the surface electrode on the middle line of the tongue.Results. MEP was registered in all cases, its average latency was 7.14 ± 0.63 ms, average amplitude — 1.79 ± 1.09 μV. There were no gender & age differences.Conclusion. In healthy people aged 18–41 years MEP from the tongue may be registered in 100% of the cases; its average latency is 7.14 ± 0.63 ms, average amplitude — 1.79 ± 1.09 μV; there are no significant age & gender differences. TMS of the tongue according to this protocol is relatively simple, not time-and efforts-consuming & may be widely implemented in clinical neurophysiology.

scholarly journals AGE DYNAMIC OF THE MOTOR EVOKED POTENTIAL FROM THE TONGUE IN HEALTHY PERSONS

2021 ◽  
pp. 1002-1006
Author(s):  
В. Б. Войтенков ◽  
В. Н. Команцев ◽  
А. В. Климкин ◽  
Е. В. Екушева ◽  
Н. В. Скрипченко ◽  
...  
Keyword(s):  
Gender Differences ◽  
Evoked Potential ◽  
Fibrous Tissue ◽  
Motor Evoked Potential ◽  
Age Difference ◽  
Average Amplitude ◽  
Tongue Muscle ◽  
Age Related ◽  
Average Latency ◽  
Healthy Persons

Целью нашей работы было определение параметров вызванного моторного ответа (ВМО)с мышц языка у здоровых лиц разного возраста при транскраниальной магнитной стимуляции (ТМС). Обследованы 62 здоровых человека 2-75 лет (34 женщины и 28 мужчин), не имеющих неврологических заболеваний и нарушений речи. Всем проводили диагностическую ТМС по одноимпульсному протоколу наложением кольцевого койла на голову в проекции точки Fz по схеме «10-20» для стимуляции прецентральной извилины и поверхностного отводящего электрода с постоянным межэлектродным расстоянием на язык по центральной линии. У всех испытуемых был зарегистрирован ВМО с мышц языка. Средняя латентность ответа составила 7,14±0,63 мс, амплитуда - 1,79±1,09 мВ. Достоверных отличий при сравнении показателей латентности и амплитуды ВМО в зависимости от гендерного фактора получено не было. Между детьми 2-17 лет и более старшими здоровыми лицами (18-55 и 56-75 лет) регистрировали достоверные отличия по показателям амплитуды и латентности ВМО с языка. В трёх возрастных группах показатели латентности составляли 6,21±0,45; 7,05±0,76; 7,27±0,64 мс соответственно, амплитуды - 0,81±0,61; 1,88±1,01; 1,69±0,92 мВ соответственно. Достоверные отличия по показателям амплитуды и латентности ВМО с языка могут отражать происходящие с возрастом изменения - удлинение кортико-лингвальных путей вследствие развития нервной системы, а также увеличение объёма языка и последующие инволюционные изменения нервной и мышечной ткани. Our aim was to determine parameters of motor evoked potential (MEP), elicited by the transcranial magnetic stimulation (TMS) from the tongue in healthy persons of different age. 62 neurologically healthy individuals without any speech problems (age range from 2 years old to 75 years, 34 females & 28 males) were enrolled. All underwent diagnostic TMS, single-pulse protocol, 90-sm round coil, Neiro-MS-D device. Coil was placed on Fz point, registration was performed by the surface electrode on the middle line of the tongue. Results. MEPs were of different appearance, but were registered in all cases, its average latency was 7,14±0,63 ms, average amplitude - 1,79±1,09 mV. There were no gender differences. Significant age difference ( p <0,001) was registered between children (age 2-17 years) and two older groups (18-55 and 56-75 years) both on latency and on amplitude. MEPs latency was in three age groups, respectively, 6,21±0,45; 7,05±0,76, and 7,27±0,64 ms. MEPs amplitudes were 0,81±0,61; 1,88±1,01 and 1,69±0,92 mV, respectively. In healthy people aged 2-75 years MEP from the tongue may be registered in 100 % of the cases; its average latency is 7,14±0,63 ms, average amplitude - 1,79±1,09 mV; there are no significant gender differences, but significant age differences. TMS of the tongue according to this protocol is relatively simple, not time-and efforts-consuming & may be widely implemented in clinical neurophysiology. There are significant differences on MEPs latencies and amplitudes in healthy persons, which may reflect age-related changes - lengthening of the cortico-lingual pathways and tongue muscle maturing in the childhood and then fibrous tissue development and other changes in nervous tissue and tongue muscle, developing with age.

scholarly journals Peculiarities of motor evoked potential in healthy children of different age

2019 ◽  
Vol 19 (4) ◽  
pp. 228-231
Author(s):  
Vladislav B. Voitenkov ◽  
N. V. Skripchenko ◽  
A. V. Klimkin ◽  
A. I. Aksenova
Keyword(s):  
Normative Data ◽  
Evoked Potential ◽  
Motor Evoked Potentials ◽  
Pediatric Population ◽  
Motor Evoked Potential ◽  
Conduction Time ◽  
Healthy Children ◽  
Abductor Hallucis ◽  
Abductor Pollicis Brevis ◽  
Pediatric Disorders

Aim of the work The implementation of the database for reference values of motor evoked potentials (MEP) in healthy children of different ages. Methods 95 healthy children were enrolled. Age ranged from 1 to 204 months. Three subgroups were established: children of 1-12 months (n=31, 18 males, 13 females), 12-144 months (n=27, 14 males, 13 females) and 144-204 (n=37, 20 males, 17 females) months. All children were healthy. Diagnostic transcranial magnetic stimulation (TMS) was performed in all patients. MEP shape, threshold, latency and amplitudes were recorded for hands (m. Abductor pollicis brevis) and legs (m. Abductor Hallucis). Central motor conduction time (CMCT) was calculated. Results. Along with age there was observed the elongation of MEP latency, gain in amplitudes and shape normalization. There were significant differences in the elongation of MEP latency between children aged of 1-12 months and children from two other subgroups (12-144 and 144-204 months). Conclusions. Our normative data can be usedfor comparative studies in the broad spectrum of pediatric disorders. Age restrictions have to be taken in a consideration when performing the TMS in pediatric population.

scholarly journals Posture-Dependent Corticomotor Excitability Differs Between the Transferred Biceps in Individuals With Tetraplegia and the Biceps of Nonimpaired Individuals

2016 ◽  
Vol 31 (4) ◽  
pp. 354-363
Author(s):  
Carrie L. Peterson ◽  
Lynn M. Rogers ◽  
Michael S. Bednar ◽  
Anne M. Bryden ◽  
Michael W. Keith ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Evoked Potential ◽  
Muscle Length ◽  
Motor Evoked Potential ◽  
Biomechanical Model ◽  
Single Pulse ◽  
Elbow Extension ◽  
Corticomotor Excitability ◽  
Potential Amplitude

Background. Following biceps transfer to enable elbow extension in individuals with tetraplegia, motor re-education may be facilitated by greater corticomotor excitability. Arm posture modulates corticomotor excitability of the nonimpaired biceps. If arm posture also modulates excitability of the transferred biceps, posture may aid in motor re-education. Objective. Our objective was to determine whether multi-joint arm posture affects corticomotor excitability of the transferred biceps similar to the nonimpaired biceps. We also aimed to determine whether corticomotor excitability of the transferred biceps is related to elbow extension strength and muscle length. Methods. Corticomotor excitability was assessed in 7 arms of individuals with tetraplegia and biceps transfer using transcranial magnetic stimulation and compared to biceps excitability of nonimpaired individuals. Single-pulse transcranial magnetic stimulation was delivered to the motor cortex with the arm in functional postures at rest. Motor-evoked potential amplitude was recorded via surface electromyography. Elbow moment was recorded during maximum isometric extension trials, and muscle length was estimated using a biomechanical model. Results. Arm posture modulated corticomotor excitability of the transferred biceps differently than the nonimpaired biceps. Elbow extension strength was positively related and muscle length was unrelated, respectively, to motor-evoked potential amplitude across the arms with biceps transfer. Conclusions. Corticomotor excitability of the transferred biceps is modulated by arm posture and may contribute to strength outcomes after tendon transfer. Future work should determine whether modulating corticomotor excitability via posture promotes motor re-education during the rehabilitative period following surgery.

P239 Muscle contraction does not always trigger the appearance of motor evoked potential polyphasia in healthy individuals

2017 ◽  
Vol 128 (9) ◽  
pp. e255
Author(s):  
Stefani Stefani ◽  
Eleftherios Papathanasiou ◽  
Ioanna Kousiappa ◽  
Savvas Papacostas
Keyword(s):  
Muscle Contraction ◽  
Evoked Potential ◽  
Motor Evoked Potential ◽  
Healthy Individuals

scholarly journals Pre-stimulus theta power is correlated with variation of motor evoked potential latency: a single-pulse TMS study

2018 ◽  
Vol 236 (11) ◽  
pp. 3003-3014 ◽  
Author(s):  
Zafer İşcan ◽  
Aaron Schurger ◽  
Marine Vernet ◽  
Jacobo D. Sitt ◽  
Antoni Valero-Cabré
Keyword(s):  
Evoked Potential ◽  
Motor Evoked Potential ◽  
Single Pulse ◽  
Theta Power

scholarly journals TMS over M1 Reveals Expression and Selective Suppression of Conflicting Action Impulses

2014 ◽  
Vol 26 (1) ◽  
pp. 1-15 ◽  
Author(s):  
A. Dilene van Campen ◽  
Max C. Keuken ◽  
Wery P. M. van den Wildenberg ◽  
K. Richard Ridderinkhof
Keyword(s):  
Correct Response ◽  
Motor System ◽  
Evoked Potential ◽  
Motor Evoked Potential ◽  
Silent Period ◽  
Single Pulse ◽  
Incorrect Response ◽  
Stimulus Location ◽  
Response Side ◽  
Selective Suppression

Goal-directed action control comes into play when selecting between competing action alternatives. Response capture reflects the susceptibility of the motor system to incitement by task-irrelevant action impulses; the subsequent selective suppression of incorrect action impulses aims to counteract response capture and facilitate the desired response. The goal of this experiment was to clarify physiological mechanisms of response capture and suppression of action impulses during conflict at the level of the motor system. We administered single-pulse TMS at various intervals preceding speeded choice responses. The correct response side was designated by stimulus color, whereas stimulus location (which could match or conflict with response side) was to be ignored. TMS pulses triggered motor evoked potential and silent period, providing sensitive indices of cortico-spinal excitation and inhibition. Motor evoked potential data showed the typical progressive increase in cortico-spinal motor excitability leading up to the imminent (correct) response, which started earlier on nonconflict than on conflict trials. On conflict trials, the irrelevant stimulus location captured the incorrect response, as expressed by an early and transient rise in excitability. Silent period data showed that, already early during the response process, inhibition of the incorrect response was stronger for conflict than for nonconflict trials. Furthermore, inhibition decreased over time for nonconflict trials facilitating the imminent correct response while maintaining higher levels of inhibition on conflict trials. In conclusion, dynamic patterns of cortico-spinal excitability provide unique physiological evidence for the expression and selective suppression of action impulses captured by competing action alternatives.

scholarly journals Long-term motor deficit in brain tumour surgery with preserved intra-operative motor-evoked potentials

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Davide Giampiccolo ◽  
Cristiano Parisi ◽  
Pietro Meneghelli ◽  
Vincenzo Tramontano ◽  
Federica Basaldella ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Brain Tumour ◽  
Evoked Potential ◽  
Corticospinal Tract ◽  
Motor Evoked Potentials ◽  
Motor Evoked Potential ◽  
Motor Deficit ◽  
Motor Deficits ◽  
Brain Tumour Surgery

Abstract Muscle motor-evoked potentials are commonly monitored during brain tumour surgery in motor areas, as these are assumed to reflect the integrity of descending motor pathways, including the corticospinal tract. However, while the loss of muscle motor-evoked potentials at the end of surgery is associated with long-term motor deficits (muscle motor-evoked potential-related deficits), there is increasing evidence that motor deficit can occur despite no change in muscle motor-evoked potentials (muscle motor-evoked potential-unrelated deficits), particularly after surgery of non-primary regions involved in motor control. In this study, we aimed to investigate the incidence of muscle motor-evoked potential-unrelated deficits and to identify the associated brain regions. We retrospectively reviewed 125 consecutive patients who underwent surgery for peri-Rolandic lesions using intra-operative neurophysiological monitoring. Intraoperative changes in muscle motor-evoked potentials were correlated with motor outcome, assessed by the Medical Research Council scale. We performed voxel–lesion–symptom mapping to identify which resected regions were associated with short- and long-term muscle motor-evoked potential-associated motor deficits. Muscle motor-evoked potentials reductions significantly predicted long-term motor deficits. However, in more than half of the patients who experienced long-term deficits (12/22 patients), no muscle motor-evoked potential reduction was reported during surgery. Lesion analysis showed that muscle motor-evoked potential-related long-term motor deficits were associated with direct or ischaemic damage to the corticospinal tract, whereas muscle motor-evoked potential-unrelated deficits occurred when supplementary motor areas were resected in conjunction with dorsal premotor regions and the anterior cingulate. Our results indicate that long-term motor deficits unrelated to the corticospinal tract can occur more often than currently reported. As these deficits cannot be predicted by muscle motor-evoked potentials, a combination of awake and/or novel asleep techniques other than muscle motor-evoked potentials monitoring should be implemented.

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