STRICTUREPLASTY AS AN ORGAN-SAVING METHOD IN PATIENTS WITH SMALL BOWEL CROHN'S DISEASE (case report)

Crohn's disease (CD) is a complex, chronic recurrent disease with transmural, segmental, granulomatous inflammation in all parts of the gastrointestinal tract with high risk of local and systemic complications. The disease is progressive, despite a wide range of modern conservative and surgical approaches. One of the most common causes of surgery for CD is strictures, which are result of prolonged, non-specific inflammation and later cicatricial changes in the intestinal wall. The occurrence of strictures is a serious clinical problem, due to the lack of effective methods of diagnosis and treatment. In fact, there are two type of surgery – resection of the affected area and organ-saving procedure. At the same time, when performing extensive resections of the small bowel, the patient loses a large area of absorption surface, which often leads to the short bowel syndrome. Recently, the majority of foreign experts prefer organ-saving procedure – strictureplasty. In this paper, we present a case of successful application of this procedure for complicated form of Crohn's disease.

Download Full-text

CROHN’S DISEASE IN CHILDREN: THE CURRENT STATE OF THE PROBLEM

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2021-100-6-78-85 ◽

2021 ◽

Vol 100 (6) ◽

pp. 78-85

Author(s):

A.S. Bekin ◽

◽

E.Yu. Dyakonova ◽

A.N. Surkov ◽

A.P. Fisenko ◽

...

Keyword(s):

Crohn’S Disease ◽

Surgical Treatment ◽

Crohn's Disease ◽

Granulomatous Inflammation ◽

Unknown Etiology ◽

Systemic Complications ◽

Current State ◽

Conservative And Surgical Treatment ◽

Scientific Ideas ◽

Local And Systemic Complications

Crohn's disease (CD) is chronic recurrent bowel disease of unknown etiology, characterized by segmental transmural granulomatous inflammation, mainly with the development of local and systemic complications. Despite the active development of conservative therapy methods, the number of drug-resistant forms of CD and complications of the disease requiring surgical treatment continues to increase. The article reflects modern scientific ideas about the methods of diagnosis, conservative and surgical treatment of CD in children.

Download Full-text

Precise Endoscopic and Pathologic Features in a Crohn's Disease Case with Two Fistula-associated Small Bowel Adenocarcinomas Complicated by an Anal Canal Adenocarcinoma

Internal Medicine ◽

10.2169/internalmedicine.52.9021 ◽

2013 ◽

Vol 52 (4) ◽

pp. 445-449 ◽

Cited By ~ 6

Author(s):

Mitsue Sogawa ◽

Kenji Watanabe ◽

Yutaro Egashira ◽

Kiyoshi Maeda ◽

Kenichi Morimoto ◽

...

Keyword(s):

Crohn’S Disease ◽

Small Bowel ◽

Crohn's Disease ◽

Anal Canal ◽

Pathologic Features ◽

Disease Case

Download Full-text

Small Bowel Adenocarcinoma Complicating Crohn's Disease: Case Series and Review of the Literature

The American Surgeon ◽

10.1177/000313480707301122 ◽

2007 ◽

Vol 73 (11) ◽

pp. 1181-1187 ◽

Cited By ~ 14

Author(s):

Lesly A. Dossett ◽

Lisa M. White ◽

Dereck C. Welch ◽

Alan J. Herline ◽

Roberta L. Muldoon ◽

...

Keyword(s):

Crohn’S Disease ◽

Small Bowel ◽

Crohn's Disease ◽

De Novo ◽

Metastatic Cancer ◽

Case Series ◽

Small Bowel Adenocarcinoma ◽

Review Of The Literature ◽

Disease Case ◽

History Of

Colonic adenocarcinoma frequently complicates inflammatory bowel disease of the colon, but small bowel adenocarcinoma (SBA) is a rare complication of Crohn's disease (CD). We present two patients with SBA in CD and review the literature with regards to CD-related SBA. A 45-year-old male with a 17-year history of ileal CD presented with obstructive symptoms but no radiographic evidence of a mass. After laparoscopic ileocolectomy and repair of incidental ileosigmoid fistula, pathology showed a T3N0 adenocarcinoma within the ileal CD. Two years after his resection he was without evidence of disease. A 59-year-old male with a 15-year history of CD presented with an acute exacerbation. Small bowel follow through demonstrated a long ileal stricture for which he underwent an ileocolic resection. Postoperative pathology confirmed a T3N1 CD-related SBA. He died from metastatic cancer 3 months later. Review of the literature identified 154 cases of SBA complicating CD with several distinguishing features from de novo SBA. Patients with SBA and CD are, as a group, younger and more likely to be male. SBA is rarely diagnosed preoperatively in these patients, and has a poor prognosis due to its advanced stage at diagnosis.

Download Full-text

Aphthous stomatitis as the debut of Crohn’s disease

Experimental and Clinical Gastroenterology ◽

10.31146/1682-8658-ecg-169-9-97-100 ◽

2020 ◽

pp. 97-100

Author(s):

O. V. Gaus ◽

V. A. Akhmedov ◽

A. S. Korshunov

Keyword(s):

Crohn’S Disease ◽

Gastrointestinal Tract ◽

Crohn's Disease ◽

Granulomatous Inflammation ◽

Aphthous Stomatitis ◽

Systemic Complications ◽

Immune Mediated ◽

Transmural Inflammation ◽

Retromolar Region

Crohn’s disease is an immune-mediated disease characterized by non-specific granulomatous transmural inflammation with segmental damage to any part of the gastrointestinal tract with the formation of extraintestinal and systemic complications. Clinical observation of patient I., 23 years old, a student who was sent for consultation to a gastroenterologist in the direction of a dentist, is presented. Active examination of the gastrointestinal tract during the inspection did not show any complaints. He considers himself ill for 6 months, when he first complained of pain in the neck, sore throat, and body temperature rise to 37.4–37.5 °C, mostly in the evening. Were treated by an otolaryngologist and a dentist without significant effect. In this connection, a biopsy of the ulcerative defect of the left retromolar region was performed, revealing noncaseating granulomatous inflammation. A follow-up examination by a gastroenterologist with colonoscopy and biopsy made it possible to establish Crohn’s disease as the true cause of aphthous stomatitis.

Download Full-text