scholarly journals Introducing a Custom-Designed Volume-Pressure Machine for Novel Measurements of Whole Lung Organ Viscoelasticity and Direct Comparisons Between Positive- and Negative-Pressure Ventilation

2020 ◽  
Vol 8 ◽  
Author(s):  
Samaneh Sattari ◽  
Crystal A. Mariano ◽  
Swathi Vittalbabu ◽  
Jalene V. Velazquez ◽  
Jessica Postma ◽  
...  
Keyword(s):  
Negative Pressure ◽  
Negative Pressure Ventilation

Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion

2018 ◽  
Vol 37 (4) ◽  
pp. 520-530 ◽  
Author(s):  
Nader S. Aboelnazar ◽  
Sayed Himmat ◽  
Sanaz Hatami ◽  
Christopher W. White ◽  
Mohamad S. Burhani ◽  
...  
Keyword(s):  
Negative Pressure ◽  
Ex Vivo ◽  
Lung Perfusion ◽  
Lung Edema ◽  
Ex Vivo Lung Perfusion ◽  
Negative Pressure Ventilation

Augmentation of phrenic neural activity by increased rates of lung inflation

1981 ◽  
Vol 50 (1) ◽  
pp. 149-161 ◽  
Author(s):  
A. I. Pack ◽  
R. G. DeLaney ◽  
A. P. Fishman
Keyword(s):  
Tidal Volume ◽  
Volume Change ◽  
Neural Activity ◽  
Negative Pressure ◽  
Spontaneous Breathing ◽  
Moving Average ◽  
Constant Flow ◽  
Lung Inflation ◽  
Negative Pressure Ventilation ◽  
Single Breath

Studies were conducted in anesthetized paralyzed dogs using a cycle-triggered constant-flow ventilator, which ventilated the animal in phase with the recorded phrenic neural activity. Intermittently tests were performed in which the animal was ventilated with a different airflow for a single breath. Increased airflows, within the range generated during spontaneous breathing, caused an increased rate of rise of the moving average phrenic neurogram and a shortening of the duration of the nerve burst. The magnitude of the increase in the rate of rise of the neurogram was related to the level of inspiratory airflow. Tests with brief pulses of airflow showed that an increase in the rate of rise of the phrenic neurogram could be produced without inflating the lung above the resting tidal volume of the animal. Similar results were obtained with negative-pressure ventilation and the effects were abolished by vagotomy. This vagally mediated augmentation of phrenic neural output may accelerate the inspiratory volume change in the lung during spontaneous breathing at hyperpneic levels.

scholarly journals Diagnosis and validation by computational fluid dynamics of poultry house with negative pressure ventilation

2019 ◽  
Vol 23 (10) ◽  
pp. 761-767
Author(s):  
Gisele C. de A. Cunha ◽  
José P. Lopes Neto ◽  
Dermeval A. Furtado ◽  
Valéria P. Borges ◽  
Elias A. Freire ◽  
...  
Keyword(s):  
Thermal Comfort ◽  
Negative Pressure ◽  
Environmental Variables ◽  
Fluid Dynamic ◽  
Air Velocity ◽  
Cfd Simulations ◽  
Heterogeneous Distribution ◽  
Poultry House ◽  
Mean Values ◽  
Negative Pressure Ventilation

ABSTRACT Negative pressure ventilation in poultry houses has been used to enable the correction of their internal microclimates, and studies point to the heterogeneous distribution of air along the aviaries and the inadequacy of the environmental variables to the recommended ranges for thermal comfort of adult birds, especially in the hottest hours of the day. This study aimed to diagnose the facilities of a poultry house in the state of Paraíba, Brazil, regarding the distribution of environmental variables and thermal comfort; develop a computational model and validate it for Computational Fluid Dynamic - CFD simulations. Air temperature (Tair), air relative humidity (RH) and air velocity (Vair) data allowed characterizing the internal environment by comparison with the recommended ranges for each variable and by the temperature-humidity-velocity index (THVI). The poultry house does not provide comfort for the housed adult birds, between 12 and 14 h, with THVI indicating alert and Tair, RH and Vair values outside the recommended ranges; the CFD model for the poultry house was validated with Tair averages collected in the field of 27.75 ± 1.35 ºC and simulated of 27.85 ± 0.55 ºC, mean values of RH collected of 83 ± 12% and simulated of 78 ± 3%, and means of Vair collected of 2.35 ± 1.35 m s-1 and simulated of 2.50 ± 1.50 m s-1.

Negative Pressure Ventilation

CHEST Journal ◽  
1989 ◽  
Vol 95 (1) ◽  
pp. 95-99 ◽  
Author(s):  
Robert D. Levy ◽  
T. Douglas Bradley ◽  
Stephen L. Newman ◽  
Peter T. Macklem ◽  
James G. Martin
Keyword(s):  
Negative Pressure ◽  
Negative Pressure Ventilation

Use of Negative Pressure Ventilation in Pediatric Critical Care

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Cynthia A. Moffitt ◽  
Kathleen Deakins ◽  
Ira Cheifetz ◽  
Jason A. Clayton ◽  
Katherine N. Slain ◽  
...  
Keyword(s):  
Critical Care ◽  
Negative Pressure ◽  
Pediatric Critical Care ◽  
Negative Pressure Ventilation

Negative Pressure Ventilation: New Uses for an Old Technique

1990 ◽  
Vol 1 (2) ◽  
pp. 313-317
Author(s):  
Gloria Sonnesso
Keyword(s):  
Nursing Care ◽  
Negative Pressure ◽  
Respiratory Function ◽  
Upper Airway ◽  
Negative Pressure Ventilation ◽  
Skin Breakdown ◽  
Dependent Patient

Negative pressure ventilation (NPV), a concept that was used in the 1940s through 1950s to support the victims of the polio epidemic, is regaining popularity. It is being used increasingly to intermittently support respiratory function in patients suffering from a variety of diseases. The use of NPV obviates the need for a surgically placed airway (if the patients’ upper airway is intact) and allows the patient to resume many of his or her normal activities. Several types of NPV are available for use and experimentation, and it is strongly recommended that the appropriate type for each patient be chosen. Nursing care of the patient on NPV is essentially the same as that of any chronically ventilator-dependent patient. Issues unique to the patient supported on NPV include: increased potential for aspiration, skin breakdown around the NPV site, and “tank shock.” Nursing plays an important role in identifying patients who may be candidates for NPV. Negative pressure ventilation may allow a formally hospital-bound patient the opportunity to be home with family and friends

scholarly journals Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Max T. Buchko ◽  
Nasim Boroumand ◽  
Jeffrey C. Cheng ◽  
Alim Hirji ◽  
Kieran Halloran ◽  
...  
Keyword(s):  
Negative Pressure ◽  
Ex Vivo ◽  
Lung Perfusion ◽  
Ex Situ ◽  
Positive Pressure ◽  
Ex Vivo Lung Perfusion ◽  
Extended Criteria Donor ◽  
Negative Pressure Ventilation ◽  
Discharge From Hospital ◽  
End Stage

AbstractLung transplantation remains the best treatment option for end-stage lung disease; however, is limited by a shortage of donor grafts. Ex situ lung perfusion, also known as ex vivo lung perfusion, has been shown to allow for the safe evaluation and reconditioning of extended criteria donor lungs, increasing donor utilization. Negative pressure ventilation ex situ lung perfusion has been shown, preclinically, to result in less ventilator-induced lung injury than positive pressure ventilation. Here we demonstrate that, in a single-arm interventional study (ClinicalTrials.gov number NCT03293043) of 12 extended criteria donor human lungs, negative pressure ventilation ex situ lung perfusion allows for preservation and evaluation of donor lungs with all grafts and patients surviving to 30 days and recovered to discharge from hospital. This trial also demonstrates that ex situ lung perfusion is safe and feasible with no patients demonstrating primary graft dysfunction scores grade 3 at 72 h or requiring post-operative extracorporeal membrane oxygenation.

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