scholarly journals Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety

2021 ◽  
Vol 8 ◽  
Author(s):  
Jiandong Zhou ◽  
Sharen Lee ◽  
Wing Tak Wong ◽  
Keith Sai Kit Leung ◽  
Ronald Hang Kin Nam ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Female Gender ◽  
Gastrointestinal Diseases ◽  
Older Age ◽  
Pressure Measurements ◽  
Specific Effects ◽  
Gender And Age ◽  
Bidirectional Relationship ◽  
Maximum Minimum

Background: There is a bidirectional relationship between blood pressure variability (BPV) and anxiety, but few studies have examined the gender- and age-specific effects of visit-to-visit BPV on incident anxiety. We examined the predictive value of BPV for the incidence of anxiety in a family clinic cohort.Methods: Consecutive patients with a first attendance to family medicine clinics in Hong Kong between January 1, 2000, and December 31, 2002, with at least three blood pressure measurements available thereafter were included. The primary endpoint was incident anxiety as identified by ICD-9 coding.Results: This study included 48,023 (50% males) patients with a median follow-up of 224 [interquartile range (IQR): 217–229] months. Females were more likely to develop incident anxiety compared to males (incidence rate: 7 vs. 2%), as were patients of older age. Significant univariate predictors were female gender, older age, preexisting cardiovascular diseases, respiratory diseases, diabetes mellitus, hypertension, and gastrointestinal diseases, various laboratory examinations, and the number of blood pressure measurements. Higher baseline, maximum, minimum, standard deviation (SD), coefficient of variation (CV), and variability score of diastolic blood pressure significantly predicted incident anxiety, as did all systolic blood pressure measures [baseline, latest, maximum, minimum, mean, median, variance, SD, root mean square (RMS), CV, and variability score].Conclusions: The relationships between longer-term visit-to-visit BPV and incident anxiety were identified. Female and older patients with higher blood pressure and higher BPV were at the highest risks of incident anxiety.

scholarly journals Gender- and Age-Specific Associations of Visit-To-Visit Blood Pressure Variability with Incident Generalized Anxiety Disorder

2021 ◽  
Author(s):  
Jiandong Zhou ◽  
Sharen Lee ◽  
Wing Tak Wong ◽  
Keith Sai Kit Leung ◽  
Ronald Hang Kin Lam ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Blood Pressure Variability ◽  
Gastrointestinal Diseases ◽  
Older Age ◽  
Generalized Anxiety ◽  
Pressure Measurements ◽  
Gender And Age ◽  
Maximum Minimum

AbstractBackgroundThere is a bidirectional relationship between blood pressure variability (BPV) and generalized anxiety disorder (GAD), but few studies have examined the gender- and age-specific effects of visit-to-visit BPV on GAD incidence. We examined the predictive value of BPV for the incidence of GAD in a family clinic cohort.MethodsConsecutive patients with a first attendance to family medicine clinics in Hong Kong between January 1st, 2000, and December 31st, 2002, with at least three blood pressure measurements available thereafter were included. The primary endpoint was incident GAD as identified by ICD-9 coding from the local Clinical Data Analysis and Reporting System.ResultsThis study included 48023 (50% males) patients with a median follow-up of 224 (IQR: 217-229) months. Females were more likely to develop GAD compared to males (incidence rate: 7% vs. 2%), as were patients of older age. Significant univariate predictors were female gender, older age, pre-existing cardiovascular diseases, respiratory diseases, diabetes mellitus, hypertension, and gastrointestinal diseases, various laboratory examinations and the number of blood pressure measurements. Higher baseline, maximum, minimum, SD, CV, and variability score of diastolic blood pressure significantly predicted GAD, as did all systolic blood pressure measures (baseline, latest, maximum, minimum, mean, median, variance, SD, RMS, CV, variability score).ConclusionsThe relationships between longer term visit-to-visit BPV and incident GAD were identified. Female and older patients with higher blood pressure and higher BPV were at the highest risks of GAD.

scholarly journals Associations between Five-Year Blood Pressure Variability and Risk of Cardiovascular Events and Mortality

2020 ◽  
Author(s):  
Jiandong Zhou ◽  
Sharen Lee ◽  
Wing Tak Wong ◽  
William KK Wu ◽  
Wai Kit Ming ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Blood Pressure ◽  
Acute Myocardial Infarction ◽  
Diastolic Blood Pressure ◽  
Blood Pressure Variability ◽  
Pressure Measurements ◽  
Time To Death ◽  
All Cause Mortality ◽  
Maximum Minimum

AbstractIntroductionBlood pressure variability, in addition to blood pressure itself, has been used as a predictor for mortality. This study examined the predictive power of baseline/latest/mean/median blood pressure and blood pressure variability measures for all-cause mortality and adverse cardiovascular outcomes.MethodsThe retrospective observational study analyzed patients who presented to family medicine clinics between 1st January, 2000 and 31st December, 2001. Blood pressure measurements were obtained over a five-year period. Standard deviation (SD), root mean square (RMS), coefficient of variation (CV) and a variability score (number of >=5 mmHg blood pressure change) were used as measures of blood pressure variability. The primary outcome was all-cause mortality and the secondary outcomes were heart failure, acute myocardial infarction, and transient ischemic attack (TIA)/stroke, with follow-up until 31 December 2019.ResultsThis study included 37540 patients (n=29597 patients with >=3 blood pressure measurements). A nonlinear inverse U-shaped relationship was observed between baseline/latest/maximum/minimum/mean/median/RMS measures of diastolic blood pressure and time-to-death for all-cause mortality (P<0.001). Higher variance/SD/CV/variability score of both systolic and diastolic blood pressure was significantly associated with increased risks of all-cause mortality and heart failure, acute myocardial infarction and TIA/stroke (P<0.001). Low baseline/latest/maximum/minimum/mean/median/RMS systolic blood pressure was significantly associated with shorter time-to-death for all-cause mortality (P<0.001).ConclusionNonlinear inverse U-shaped relationships were observed between blood pressure and its variability measures and all-cause mortality. Higher blood pressure variability was associated with increased risk of all-cause mortality, heart failure, acute myocardial infarction and TIA/stroke.

The use of successive blood-pressure measurements to estimate blood-pressure variability

1988 ◽  
Vol 11 (5) ◽  
pp. 435-446 ◽  
Author(s):  
Michael S. Glasgow ◽  
Bernard T. Engel ◽  
Burton C. D'Lugoff
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Pressure Measurements

Within-Visit Blood Pressure Variability in an Unselected Adult Population

2021 ◽  
Vol 34 (10) ◽  
pp. 1125-1126
Author(s):  
Xin Chen ◽  
Shao-kun Xu ◽  
Yan Li ◽  
Zhe Hu ◽  
Hong-yu Wang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Standard Deviation ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Coefficient Of Variation ◽  
Blood Pressure Variability ◽  
Adult Population ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Pressure Measurements

Abstract Background To investigate blood pressure variability among 3 successive blood pressure measurements in an unselected nationwide population in China. Methods A total of 77,549 participants were included from measurements in May 2017 in China. Blood pressure was measured 3 times consecutively with a half minute interval. Blood pressure variability was estimated with the standard deviation and coefficient of variation of the systolic and diastolic blood pressure. Results Not all participants showed a decreasing trend with increasing number of measurements. In fact, 14% of the participants showed at least 5 mm Hg increase in systolic blood pressure. The coefficient of variation of systolic and diastolic blood pressure in women was higher than in men [(4.2 ± 3.3)% vs. (4.1 ± 3.3)%, (4.7 ± 4.0)% vs. (4.6 ± 4.1)%; P &lt; 0.05]. The differences were significant (P &lt; 0.01) among different groups of age and blood pressure levels. Multiple linear regression analysis showed that the systolic blood pressure variability indexes were inversely associated with age but positively associated with the level of the first systolic blood pressure reading (P &lt; 0.01). The systolic blood pressure standard deviation and coefficient of variation in females were higher than in males (P &lt; 0.01). Conclusions Not all subjects demonstrate a decreasing trend with increasing number of blood pressure measurements. Within-visit blood pressure variability varies with age, gender, and blood pressure.

ASSA13-14-27 The Impact of Blood Pressure Levels, Gender and Age on Within-Visit Systolic Blood Pressure Variability

Heart ◽  
2013 ◽  
Vol 99 (Suppl 1) ◽  
pp. A66.3-A66
Author(s):  
Su Hai ◽  
Hu Weitong ◽  
Peng Qiang ◽  
Hong Dezhi ◽  
Ma Jianyong ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Pressure Variability ◽  
Gender And Age ◽  
Systolic Blood Pressure Variability ◽  
The Impact

Extension of indications for local application of Dolgit cream for vertebrogenic pain syndromes

1997 ◽  
Vol 78 (3) ◽  
pp. 230-231
Author(s):  
D. V. Kamzeev ◽  
V. F. Bogoyavlensky ◽  
R. M. Gazizov ◽  
V. P. Veselovsky
Keyword(s):  
Risk Factors ◽  
Female Gender ◽  
Gastrointestinal Diseases ◽  
Older Age ◽  
Gastric Bleeding ◽  
Drug Induced ◽  
Pain Syndromes ◽  
Gastrointestinal Pathology ◽  
History Of ◽  
Inflammatory Drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve the pain (algic) syndrome. However, their oral use is limited because of the development of drug-induced gastropathies, including gastric bleeding, gastric or intestinal ulcer perforations. Risk factors for drug-induced gastropathies include older age, female gender, smoking, taking corticosteroids along with NSAIDs, and a history of gastrointestinal pathology (ulcers, gastritis, bleeding). The risk of gastropathy complications is especially high in those who suffer from chronic gastrointestinal diseases.

scholarly journals Short-Term but not Long-Term Blood Pressure Variability Is a Predictor of Adverse Cardiovascular Outcomes in Young Untreated Hypertensives

2020 ◽  
Vol 33 (11) ◽  
pp. 1030-1037
Author(s):  
Francesca Saladini ◽  
Claudio Fania ◽  
Lucio Mos ◽  
Olga Vriz ◽  
Andrea Mazzer ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Ambulatory Monitoring ◽  
Female Gender ◽  
Future Research ◽  
Office Visits ◽  
Short Term ◽  
Prognostic Information ◽  
Predictive Capacity

Abstract Background Whether blood pressure variability (BPV) measured with ambulatory monitoring (short-term BPV) or computed from office visits (long-term BPV) are related to each other and carry similar prognostic information is not well known. We investigated the independent determinants of short-term and long-term BPVs and their predictive capacity for the development of major adverse cardiovascular and renal events (MACEs) in a cohort of young hypertensive participants. Methods Long-term BPV was calculated as visit-to-visit SD and average real variability from office blood pressure (BP) measured during 7 visits, within 1 year. Short-term BPV was calculated as weighted 24-hour SD and coefficient of variation. Hazard ratios (HRs) for risk of MACE were computed from multivariable Cox regressions. Results 1,167 participants were examined; mean age was 33.1 ± 8.5 years. Variables independently associated with 24-hour systolic SD were 24-hour systolic BP, low physical activity, smoking, baseline office pulse pressure, systolic BP dipping, and diastolic white coat effect, while those associated with long-term BPV were mean systolic BP, age, female gender, and baseline office heart rate. During a median follow-up of 17.4 years 75 MACEs occurred. In Cox analysis only short-term BPV resulted a significant predictor of MACE (HR, 1.31 (1.07–1.59); P = 0.0086), while no index of long-term BPV was independently associated with outcome. Conclusions In young hypertensive subjects only short-term BPV resulted a significant predictor of MACE on top of traditional ambulatory BP monitoring parameters. Whether reduction of short-term BPV with therapy may reduce the cardiovascular risk independently from the effects on 24-hour BP is a matter for future research.

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